• Title/Summary/Keyword: 변이음

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Current trends in orthodontic patients in Seoul National University Dental Hospital (서울대학교 치과병원 교정과에 내원한 부정교합 환자의 최근 경향)

  • Im, Dong-Hyuk;Kim, Tae-Woo;Nahm, Dong-Seok;Chang, Young-Il
    • The korean journal of orthodontics
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    • v.33 no.1 s.96
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    • pp.63-72
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    • 2003
  • Over the Past decades, the number of Patients seeking orthodontic treatment has increased markedly with socioeconomic development and change of recognition on appearance. The purpose of this study was to provide an epidemiologic data base related to the orthodontic treatment need. We could take an adequate information regarding the characteristics of orthodontic patients, and the changing trends about treatment mordality. Distrubution and treands were Investigated in 676 patients who had been examined and diagnosed at Department of orthodontics, Dental Hospital, Seoul National University from January to June in 1992 and 2002. 1. Sex distribution of patients changed from 1:2.1 to 1:1.5 (male female). 2. In 2002, are distribution had shown $7\~12$ year-old group being the largest$(32.0\%)$ and percentage of $19\~24,\;13\~18,\;over\;25,\;4\~6,\;0\~3$ year-old group were $24.0\%,\;21.6\%,\;14.2\%,\;5.8\%,\;2.4\%$ respctively. Compared with data in 1992, the number of adult patients highly increased. 3. With regard to Angle classification, each percentage of Class I, Class II div 1, Class II div 2, and Class III malocclusion were $25.0\%,\;20.9\%,\;3.4\%,\;and\;48.1\%$ respectively in 2002. 4. Geographic distribution showed that most of the patients visited $(37.0\%)$ lived in northeast of Seoul in 2002. 5. Mandibular prognathism showed the highest percentage in chief complaints. The percentages of crowding and facial asymmetry were $14.2\%\;and\;11.8\%$ in 2002. Patients with facial asymmetry increased significantly. 6. Percentages of patients treated with fixed appliance and orthognathic surgery were $38.0\%\;and\;25.0\%$ in 2002. Patients needed to observe the growth pattern comprised $13.0\%$ with increasing trends. The use of chin cap reduced and the percentage of ortognathic surgery and growth observation increased significantly.

Clinical and Polysomnographic Characteristics of REM Sleep-Dependent Obstructive Sleep Apnea (REM 수면 의존성 폐쇄성 수면무호흡증 환자의 임상적 특성과 수면 변인에 관한 연구)

  • Lee, Yu-Jin;Lee, Soon-Jeong;Kang, Dong-Jin
    • Sleep Medicine and Psychophysiology
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    • v.15 no.2
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    • pp.77-81
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    • 2008
  • Introduction: REM sleep which shows characteristic muscle atonia and increased resistance of upper respiratory track is known to be vulnerable to sleep apnea. Previous studies reported that REM sleep-dependent (or related) obstructive sleep apnea syndrome (REM-dependent OSA) could be one of sleep disordered breathing. The present study aimed to investigate clinical findings and polysomnographic variables of REM-dependent OSA. Methods: Fifty-six patients diagnosed with mild to moderate obstructive sleep apnea by overnight polysomnography (5$53.7{\pm}16.7$ years, 42 males). REM-dependent OSA was defined as AHI-REM/AHI-NREM ratio>2. We compared clinical and polysomnographic findings between REM-dependent OSA and No REM-dependent OSA patients. Results: Among 56 patients, 37.5% (n=21, average age of $52.3{\pm}19.7$ years, 14 males) met the REM-dependent OSA criteria. There were no significant differences in age, sex and body mass index between two groups. After controlling for age, sex, body mass index and periodic leg movements index, REM-dependent OSA patients showed significantly lower AHI, lower number of oxygen desaturation events and higher stage 2 sleep proportion compared to No REM-dependent OSA patients (p=0.010, p=0.006, p=0.031, respectively). After controlling for age, sex, body mass index and periodic legs movements index, AHI-REM was positively correlated with the number of oxygen desaturation events in REM-dependent OSA group (p=0.002). Conclusion: Current results suggested that 37.5% of patients with mild to moderate severity of obstructive sleep apnea could be classified into REM-dependent OSA. REM-dependent OSA was more common in mild severity of OSA, equally prevalent in both sexes and accompanied with sleep architecture changes, i.e. increased proportion of stage 2. In addition, apneic events during REM sleep in REM-dependent OSA were related to oxygen desaturation.

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Effect of the Fatty Acid Synthase Gene for Beef Quantity Traits in Hanwoo Breeding Stock (한우 Fatty Acid Synthase (FASN) 유전자 반수체형의 후대검정우 육량 및 육질에 미치는 영향)

  • Kim, Sang-Wook;Lee, Jun-Heon;Kim, Jin-Ho;Won, You-Seog;Kim, Nae-Soo;Kim, Kwan-Suk
    • Journal of Animal Science and Technology
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    • v.52 no.1
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    • pp.9-16
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    • 2010
  • A previous study has shown that the g.17924G>A polymorphism of fatty acid synthase (FASN) is associated with unsaturated fatty acid composition in the Hanwoo beef, hence this study was conducted to evaluate the effect of single nucleotide polymorphisms (SNPs) within FASN gene on the selection phenotypes of Hanwoo breeding stock. A total of 925 progeny test steers were used to genotype g.11280G>A, g.13125T>C, and g.17924G>A polymorphisms and significant associations were found among g.11280G>A, g.17924G>A, and carcass traits, such as carcass weight, backfat thickness, and beef quantity index. No significant association was found between g.13125T>C and carcass traits. Although the degree of linkage disequilibrium (LD) was not strong among g.11280G>A, g.13125T>C, and g.17924G>A in the LD analysis, four major haplotype classes were formed with the genotypic information within the FASN gene; the frequencies of the halpotypeswere -GCG-[0.378], -ATG-[0.301], -GTA-[0.191], and -ACG-[0.063], respectively. Phenotypic association was performed among these haploptypes, and the haplotype 2 (-ATG-)was significantly associated with higher carcass weight when compared to the other haplotypes, i.e. haplotype 1 (-GCG-) and haplotype 3 (-GTA-). A copy number of the FASN haplotype 3 (-GTA-) had also a significant association with carcass weight of subjects. In conclusion, it was observed that two polymorphisms (g.11280G>A and g.17924G>A) and their haplotypes within the FASN gene are consistently associated with carcass traits. Therefore, it is desirable to use the FASN polymorphisms for pre-selection program as genetic marker with improved carcass yield and beef quality of the Hanwoo sire at the Hanwoo Improvement Center as well as for commercial Hanwoo producers, the FASN genotypic information can be used for a part of selecting Hanwoo dam for superior calf production.

Relationship between Meteorological Factors and Lint Yield of Monoculture Cotton in Mokpo Area (목포지방 기상요인과 단작목화의 생육 및 섬유수량과의 관계)

  • 박희진;김상곤;정동희;권병선;임준택
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.2
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    • pp.142-149
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    • 1995
  • This study was conducted to investigate the relationships between yearly variation of climatic components and yearly variations of productivity in monoculture cotton. In addition, correlation coefficients among yield and yield components were estimated. The data of yield and yield components from the four varieties(Kinggus, Yongdang local. 113-4, 380) were collected from 1978 to 1992 in Mokpo area. The meteorological data gathered at the Mokpo Weather Station for the same period were used to find out the relationships between climatic components and productivity. Yearly variation of the amount of precipitation and number of stormy days in July are large with coefficients of the variations(C.V)84.89 and 97.05%, respectively, while yearly variation, of the average temperature, maximum temperature, minimum temperature from May to Sep. are relatively small. Seed cotton yield before frost in Sep. and Oct. very greatly with C.V. of 68.77, 78.52%, respectively. Number of boll bearing branches and lint percentage show more or less small in C.V. with 11.77 and 19.13%, respectively and flowering date and boll opening date show still less variation. Correlation coefficients between precipitation in May and number of boll bearing branches, duration of sunshine in July and number of bolls per plant, maximum temperature in July and total seed cotton before the frost in Sep., Oct., and Nov. evaporation in Aug. are positively sig-nificant at the 1% level. There are highly significantly positive correlated relationships among yield(total seed cotton) and yield components. Total seed cotton yield(Y) can be predicted by multiple regression equation with independent variables of climatic factors in July such as monthly averages of average temperature($X_1$), maximum temperature($X_2$) and minimum temperature($X_3$), monthly amount of precipitation ($X_4$), evaporation($X_5$), monthly average of relative humidity($X_6$), monthly hours with sunshine($X_7$) and number of rainy days($X_8$). The equation is estimatedas Y =-1080.8515 + 144.7133$X_1$+15.8722$X_2$ + 164.9367$X_3$ + 0.0802$X_4$ + 0.5932$X_5$ + 11.3373$X_6$ + 3.4683$X_7$- 9.0846$X_8$. Also, total seed cotton yield(Y) can be predicted by the same method with climatic components in Aug., Y =2835.2497 + 57.9134$X_1$ - 46.9055$X_2$ - 41.5886X$_3$ + 1.2559$X_5$ - 21.9687$X_6$ - 3.3763$X_7$- 4.1080$X_8$- 17.5586$X_9$. And the error between observed and theoretical yield were less with approached linear regression.

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Nitrogen Responses of Rice Varieties on Grain Yield and Other Agronomic Characters (질소시용수준에 따른 수도품종별 생육 및 수량의 변이)

  • ;Jae-Young Cho;Jong-Hoon Lee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.22 no.2
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    • pp.1-17
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    • 1977
  • Nitrogen responses to yield and other agronomic characters were studied using four rice varieties, Tongil, Jinheung, Milyang 23, and Yushin, at six nitrogen levels, 0, 10, 15, 20, 25 and 30kg/10a, in a silt loam soil at the Crop Experiment Station, Suweon, Korea, in 1976. Grain yields of Milyang 23 and Tongil were much higher than those of Jinheung and Yushin at high nitrogen levels (15-30kg/10a). Optimum nitrogen levels of the rice varieties, Tongil, Milyng 23, Yushin, and Jinheung, estimated by intersecting straight line, were 22, 19, 19, and 12kg/10a, respectively. Morpshological characters, dry matter production before and after heading, and yield components were dicussed in relation to the nitrogen responsivenees of the rice varieties. In addition, relationships between yield, yield components, and other agronomic characters were discussed to obtain some informations for higher rice yield.

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Reproductive Ecology of the Silver Pomfret Pampus argenteus on the West Coast of Korea (한국 서해산 병어, Pampus argenteus의 번식생태)

  • Chung, Ee-Yung;Bae, Joo-Seung;Kang, Hee-Woong;Lee, Hwang-Bok;Lee, Ki-Young
    • Development and Reproduction
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    • v.12 no.2
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    • pp.169-181
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    • 2008
  • Reproductive ecology of the silver pomfret, Pampus argenteus were investigated by histological observations and morphometric data. Samples were collected by the stow net at the coastal area of Jaun-Do, Muan-gun, Korea, from January to December, 2006. P. argenteus is dioecious, the ovary is composed of many ovarian lobules, showing a pair of saccular structure, and the testis is composed of many seminiferous lobules, showing a pair of lobular structure. From February (growing stage) to September (after spawning), monthly changes in the gonadosomatic index, hepatosomatic index, and condition factor in females and males showed similar patterns with the gonad developmental phases. Judging from the results of their indice, it is assumed that spawning in females and males occur from May to July. The reproductive cycle can be classified into five successive stages in females: early growing stage (February to March), late growing stage (March to April), mature stage (March to July), ripe and spent stage (May to July), and recovery and resting stage (July to February); in males, the cycle can be divided into four successive stages: growing stage (February to April), mature stage (March to June), ripe and spent stage (May to July), and recovery and resting stage (July to February). According to the frequency distributions of egg diameters in the breeding season, P. argenteus is presumed to be spring-summer spawning species and polycyclic species to spawn 2 times or more during one spawning season. Number of total eggs in absolute fecundity were proportional to body length and body weight, respectively. Number of total eggs in absolute fecundity per body weight were also proportional to the body length, but if the increase of body weight considerably increased, rather total eggs in relative fecundity decreased with the increase of body weight. Percentage of first sexual maturity of P. argenteus were over 50% in females and males of 12.1 to 15.0 cm in body length, and 100% for fishes over 18.1 cm in length. Therefore, both sexes were regarded to be sexually mature at one year of age.

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Decomposition of 2,4,6-Trinitrotoluene (TNT) by Gamma Ray Irradiation (감마선 조사에 의한 2,4,6-Trinitrotoluene (TNT)의 분해)

  • Lee, Byung-Jin;Lee, Myun-Joo
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.1
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    • pp.1-10
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    • 2005
  • The purpose of this study was to evaluate the potential of a gamma irradiation to decompose 2,4,6-trinitrotoluene(TNT) in an aqueous solution. The decomposition reaction of TNT by gamma irradiation was a pseudo first-order kinetic over the applied initial concentrations($25{\sim}100mg/L$). The dose constant was strongly dependent on the initial TNT concentration. The removal of TNT was more efficient at pH below 3 and at pH above 11 than at neutral pH(pH 5-9). The required irradiation dose to remove over 99% of TNT was 40, 80 and 10 kGy, individually at pH 2, 7 and 13. The dose constant was increased by 1.6 fold and over 15.6 fold at pH 2 and 13, respectively, when compared with that at pH 7 When irradiation dose of 200 kGy was applied, the removal efficiencies of TOC were 91, 46 and 53% at pH 2, 7 and 13, respectively. Ammonia and nitrate were detected as the main nitrogen byproducts of TNT and glyoxalic acid and oxalic acid were detected as organic byproducts. The results showed that a gamma irradiation was an attractive method for the decomposition of TNT in an aqueous solution. However, regarding the application of high energy radiation for the TNT decomposition and mineralization, an application of an acidic pH below 3 to the solution before irradiation should be considered.

Growth Characteristics and Yield of "Baeck Ji 1" a New High Variety of Angelica dahurica (白芷 新品種 "白芷 1號" 의 主要特性 및 收量性)

  • 정상환
    • Korean Journal of Plant Resources
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    • v.10 no.1
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    • pp.100-104
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    • 1997
  • A new baekji(Angelica dahurica Bentham et Hooker) variety, Baekji l, was developed through a pure line selection at the Gyeongbug Provincial RDA during the period of 1990 to 1995. The variety was characterized to have high plant height. Long root length and large root diameter as compared with a check varicty of Bonghwa baekji but emergence date, flowering date and leaf number of Baekji l was similar to that of the check variety, and it was also more tolerant to nematode and heat stress. Peeled root color of Backji l was yellowbrown but number of the lateral root of the variety was greater. The dried-root yield of Baekji l in yield trial, regional adaptation trial and farmer's field trial was always $21\sim31%$ higher than that of the check variety.

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Anger and Alexithymia in Women with Premenstrual Syndrome (월경전기 증후군 여성들에서 분노 및 감정표현불능증)

  • Suh, Shin-Young;Kim, Mi-Young;Lee, Sang-Hyuk;Choi, Tae-Kyou;Kim, Keun-Hyang;Kim, Eun-Kyung;Park, Seon-Eun;Kim, Yong-Woo;Kim, Seo-Young;Yook, Keun-Young
    • Korean Journal of Psychosomatic Medicine
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    • v.14 no.2
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    • pp.108-115
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    • 2006
  • Objectives : Objectives of this study was to explore the relationships between anger, alexithymia and premenstrual syndrome(PMS). Methods The subjects included 125 women with PMS and 58 women with non-PMS assessed by Daily record of Severity of Problems(DRSP) and Shortened Premestrual Assessment Form(SPAE). Anger level was assessed by anger expression scale. The level of alexithymia was assessed by Toronto alexithymia scale. We compared the scores of anger, alexithymia between PMS group and no-PMS group. Results : The mean scores of anger in(p=0.04), anger total(p=0.01) were significantly higher in women with PMS compared to control subjects. and the mean scores of alexithymia(p=0.04) were also significantly higher in women with PMS compared to control subjects. Conclusions : This study showed that the level of anger and alexithymia could be higher in women with PMS compared to control subjects, and that symptoms of PMS could be associated with anger and alexithymia. therefore, It would be better to consider the level of anger and alexithymia in treating and evaluating women with PMS.

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Expression in Eschepichia coli of a Cloned Bacillus thuringiensis subsp. kurstaki HDI In-secticidal Protein Gene. (클로닝된 Bacillus thuringiensis subsp. kurstaki HDI 살충성 단백질 유전자의 대장균에서의 발현)

  • 황성희;차성철;유관희;이형환
    • Microbiology and Biotechnology Letters
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    • v.26 no.6
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    • pp.497-506
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    • 1998
  • The expression in Escherichia coli of a cloned insecticidal protein (ICP) gene from Bacillus thuringiensis var. kurstaki HD1 in pHLN1-80 (+) and pHLN2-80(-) plasmids was investigated through deletions in promoters, transcription start point, and termination region. Six recombinant plasmids were constructed in an attempt to analyze the overexpression of the ICP in relations to its gene structure. The amounts of ICP produced from the recombinants were measured by SDS-PAGE and confirmed by Western blot analysis. One clone was not overexpressed which having only -80 bp (contained BtI promoter) part of the ICP gene promoter (without Plac promoter), the right-oriented ICP gene and the termination region. Removal of 350 bp from upstream region of the Plac of the clone pHLN2-80 (-) resulted in overexpression of the ICP. One clone was not overexpressed in which the clone consisted of -72 bp part of the ICP promoter without the transcription start point and the transcriptional termination region, and having the right-oriented ICP gene sequence. One clone consisting of the inverted ICP gene sequence, the -72 bp ICP gene promoter, and without the termination region caused overexpression. One clone which consisted of the inverted ICP gene, the -72 bp ICP gene promoter and the termination sequence was overexpressed. These results indicated that the Plac promoter, transcription termination region, the inverted ICP gene insertion, and the -80 bp or -72 bp part of the ICP gene promoters were concerned in the overexpression of the ICP gene in the recombinant plasmid, and also the overexpression mechanism might result from the disruption of the transcription-suppressing regions in the promoter regions.

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