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Measurement of Mucin Amounts Using RTO3 in Patients with Chronic Airway Disease (만성 기도질환에서 흰쥐 뮤신에 대한 단 세포군 항체(RTO3)를 이용한 뮤신 측정에 관한 연구)

  • Kim, Do-Jin;Kim, Ki-Up;NamGung, Eun-Kyang;Uh, Soo-Taek;Kim, Young-Hoon;Shin, Chan-Young;Ko, Kwang-Ho;Park, Choon-Sik
    • Tuberculosis and Respiratory Diseases
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    • v.47 no.6
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    • pp.786-796
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    • 1999
  • Background: It has been anticipated that the amount and composition of mucin are changed in patients with chronic airway diseases. We evaluated whether RTO3(mAb against rat tracheal mucins) could quantify the amount of mucin from the airway in the patients with chronic airway diseases. Methods and results; 1) RTO3 was bound to high molecular weight of mucin based on Western blot in sputum and BALF from patients with chronic airway diseases. 2) The goblet cells and submucosal glands in main bronchus from human were observed by PAS stain. And immunohistochemical stain with RTO3 showed immunoreactivity on some goblet cells. 3) The amount of mucin was more increased in patients with chronic airway diseases compared to those in normal subjects. 4) In the exacerbation of asthmatics, mucin amounts were more increased than stable asthmatics. Conclusion: We suggested that secreted mucin in chronic airway diseases can be quantified by ELISA with RTO3.

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A Trend of Back Ground Surface Settlement of Braced Wall Depending on the Joint Dips in Rocks under the Soil Strata (복합지반 굴착 시 암반층 절리경사 각도별 흙막이 벽체 배후 지표침하의 경향)

  • Bae, Sang-Su;Lee, Sang-Duk
    • Journal of the Korean Geotechnical Society
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    • v.32 no.11
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    • pp.83-96
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    • 2016
  • The surface settlement of the back ground of a braced wall due to the ground excavation has the great influence on the safety of the surrounding area. But it is not easy to predict the settlement of the surrounding area due to proud excavation. Estimation of the settlement of the surface ground induced by the deformation of the braced wall is performed by FEM and empirical method (Peck, Clough etc). In this research, surface settlement of the back ground braced wall depending on the joint dips in rocks during excavating the composit ground was measured at the large scale model test (standard: $0.3m{\times}0.3m{\times}0.5m$). The scale of model test was 1/14.5 and the ground was excavated in ten steps. Earth pressure on the braced wall and ground surface settlement on the back ground of a braced wall were investigated. The surface settlement during the excavation depended on the joint dips in rocks on of the ratio of rock layer. Maximum earth pressure and maximum surface settlement were masured at the same excavation step. In accordance with the increase of the rock layer dips and rock layer ratio, the ground surface settlement increased. The maximum ground surface settlement was 17 times larger at 60 degree joint dips in rocks than that of the horizontal ground conditions. And the position of the maximum surface settlement by empirical method was calculated at the point, which was 17%~33% of excavation depth. In accordance with the increase of the rock layer dips and rock layer ratio, the ground maximum surface settlement increased. The ground surface settlement of composite ground is smaller than that of the empirical.

SOM-Based $R^{*}-Tree$ for Similarity Retrieval (자기 조직화 맵 기반 유사 검색 시스템)

  • O, Chang-Yun;Im, Dong-Ju;O, Gun-Seok;Bae, Sang-Hyeon
    • The KIPS Transactions:PartD
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    • v.8D no.5
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    • pp.507-512
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    • 2001
  • Feature-based similarity has become an important research issue in multimedia database systems. The features of multimedia data are useful for discriminating between multimedia objects. the performance of conventional multidimensional data structures tends to deteriorate as the number of dimensions of feature vectors increase. The $R^{*}-Tree$ is the most successful variant of the R-Tree. In this paper, we propose a SOM-based $R^{*}-Tree$ as a new indexing method for high-dimensional feature vectors. The SOM-based $R^{*}-Tree$ combines SOM and $R^{*}-Tree$ to achieve search performance more scalable to high-dimensionalties. Self-Organizingf Maps (SOMs) provide mapping from high-dimensional feature vectors onto a two-dimensional space. The map is called a topological feature map, and preserves the mutual relationships (similarity) in the feature spaces of input data, clustering mutually similar feature vectors in neighboring nodes. Each node of the topological feature map holds a codebook vector. We experimentally compare the retrieval time cost of a SOM-based $R^{*}-Tree$ with of an SOM and $R^{*}-Tree$ using color feature vectors extracted from 40,000 images. The results show that the SOM-based $R^{*}-Tree$ outperform both the SOM and $R^{*}-Tree$ due to reduction of the number of nodes to build $R^{*}-Tree$ and retrieval time cost.

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A Study on the Stability Fatigue according to the Accommodation Change due to the Use of Smartphone (스마트폰의 사용으로 인한 조절 변화에 따른 안정피로도에 대한 연구)

  • Kim, Bong-Hwan;Han, Sun-Hee;Park, Seon-Mi;Bae, Sang-Bin;Woo, Yong-Jun;Song, Gyeong-Jun;Bang, Eun-Min;Seo, Da-Eun
    • Journal of Korean Clinical Health Science
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    • v.8 no.1
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    • pp.1362-1368
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    • 2020
  • Purpose. In this study, The change of the accommodation function due to the use of a smartphone was objectively evaluated using an Auto Refractokeratometer and was to investigate the effect of accommodation response and microfluctuations of accommodation on stable fatigue. Methods. Twenty subjects (20 males, 20 females) who had no abnormalities in ophthalmic disease and strabismus, diplopia, suppression, convergence and ocular movement, and corrected visual acuity and unaided visual acuity of 0.8 or more were performed. The average age of the participants is (21.78 ± 1.78) years old. The refractive power of the eye was measured using an Auto Refractokeratometer (Speedy-i K-model, Righton Mfg Co. Tokyo Japan), and the equivalent spherical power was automatically calculated from the measured refractive power. The accommodation response amount was calculated for the accommodation stimulation amount in 8 steps in 0.5D increments from + 0.50D to -3.00D in the calculated equivalent spherical power. The microfluctuations of accommodation in the high frequency region was calculated according to the change in the amount of the accommodation stimulus. At this time, the spectral power of the microfluctuations of accommodation was analyzed by Fast Fourier Transformation (FFT). Results. After using the smartphone, it was found that the accommodation response to accommodation stimulation decreased and the microfluctuations of accommodation increased. Conclusions. It can be said that the use of a smartphone affects the accommodation response and the microfluctuations of accommodation, thereby causing a accommodative stable fatigue. Therefore, it is thought that the use of a smartphone for a long time may bring about a change in the accommodation function.

An Overview on the Physicochemical Properties and Photocatalytic Pollutant Removal Performances of TiO2-incorporated Cementitious Composites (TiO2 혼입 시멘트 복합체의 물리·화학적 특성 및 광촉매 반응을 이용한 오염물 제거 성능에 대한 개요)

  • Seo, J.H.;Yoon, H.N.;Kim, S.H.;Bae, S.J.;Jang, D.I.;Kil, T.G.;Park, S.M.;Lee, H.K.
    • Composites Research
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    • v.33 no.2
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    • pp.68-75
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    • 2020
  • Recently, the use of TiO2 as a phtocatalyst has been diversely investigated due to its excellent durability performance and high photocatalytic reaction efficiency. Active researches have particularly focused on the development of TiO2-incorporated cementitious composites in order to remove the atmospheric pollutants. Furthermore, the potential utilization of TiO2-incorporated cementitious composites as road accessories such as tunnels, road median separators and soundproof walls in the form of tiles, blocks and structural components has been widely examined. In this regard, a thorough understanding on the material characteristics of TiO2-incorporated cementitious composites should be preceded. The present overview article, therefore, revisits previous studies of TiO2-incorporated cementitious composites and summarizes their various physicochemical properties and atmospheric pollutants removal performance.

Forecasting of Probability of Accident by Analizing the Traffic Accident Data : Main Intersections on Arterial Roads in Busan (교통사고 데이터분석을 통한 교통사고 위험도 산정 : 부산시 주간선도로 주요교차로를 대상으로)

  • Jung, Kun Young;Bae, Sang Hoon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.37 no.1
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    • pp.111-117
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    • 2017
  • The purpose of forecasting the traffic accident is to reduce the traffic accident. Therefore, the goal of this study is to provide severity of the accident by Forecasting of Probability of Accident. In Korea, accident data are distributed to the public via internet that includes numbers of accident and fatality as well. And crude level of accident severity in accordance with weather information for metropolitan city level are available by weekly. However, It can not reflect personal needs at specific origin of the travel for a certain traveller. This study aims to consider 68 major intersections with precipitation data, and eventually introduces link based accident severity. In estimating the accident severity both dynamic data such as drivers' characteristics, driving conditions and static data such as geometry of road, intersection characteristics are considered. Also, we identifies accident severity according to the accident type - 'vehicle to vehicle,' 'vehicle to person.' Finally, the outcomes of this study suggests taylor-made accident severity information for a specific traveller for a certain route.

Incidence of Microbial Growth from the Tip of the Embryo Transfer Catheter after Embryo Transfer in Relation to Clinical Pregnancy Rate following In-vitro Fertilization and Embryo Transfer (체외수정시술시 배아이식 후 배아이식도관 말단부에서의 미세균주 배양율과 임상적 임신율과의 관계)

  • Lee, Kyoung-Jin;Bai, Sang-Wook;Kim, Jeong-Yeon;Kim, Jin-Young;Lee, Byung-Seok;Park, Ki-Hyun;Cho, Dong-Jae;Song, Chan-Ho
    • Clinical and Experimental Reproductive Medicine
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    • v.26 no.3
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    • pp.339-344
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    • 1999
  • Objective: To evaluate incidence of microbial growth from the tip of the embryo transfer catheter after embryo transfer in relation to clinical pregnancy rate following in-vitro fertilization and embryo transfer. Method: This study was performed prospectively at the time of transcervical embryo transfer following conventional in-vitro fertilization and intracytoplasmic sperm injection procedures. Sixty three patients were enrolled in this study. Microbiological cultures were performed on endocervical swabs and embryo transfer catheter tips. Results: Positive microbial growths were observed from endocervical swabs in 45 (71.4%) women and from catheter tips in 30 (47.6%) women. There was no statistically significant difference seen in the mean number of oocytes fertilized or number and grade of embryos transferred between the group of patients without growth and the group of patients with positive microbial growth from catheter tips. The clinical pregnancy rate were 30.3% in the group of patients without growth and 13.3% in the group with positive microbial growth from catheter tips. This difference in clinical pregnancy rates was statistically significant. Conclusion: Our finding is that microbial contamination at embryo transfer may influence implantation rates. The major questions arising from our finding are whether eradication of endocervical micro-organisms is possible and whether their eradication will improve implantation rates.

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Change in the Physicochemical Properties of Dolsan Leaf Mustard under Salting Conditions (절임조건에 따른 돌산갓의 이화학적 특성 변화)

  • Bae, Sang-Ok;Wi, Sung-Dol;Lim, Hyun-Soo;Choi, Myeong-Rak
    • Food Science and Preservation
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    • v.18 no.4
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    • pp.502-507
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    • 2011
  • To investigate the optimal salting conditions, the physicochemical properties of Dolsan leaf mustard were compared under various salting times and using various washing methods and storage temperatures at 10% saline. On the other hand, the cell number of lactic-acid bacteria in Dolsan leaf mustard salted under the optimal conditions was also examined during the 50-day storage. The results of the sensory evaluation of the crispness value of the Dolsan leaf mustard treated with stepwise washing after 8h salting showed the optimal conditions for long-term preservation. The pH of the salted Dolsan leaf mustard decreased with the increase in the lactic-acid bacteria during the storage at $4^{\circ}C$. The cutting energy slowly increased during the storage, but the cutting energy of the salted Dolsan leaf mustard treated with stepwise washing remained at the initial values. The color of the salted Dolsan leaf mustard did not change during 40-day storage, but the mustard turned brown after 50-day storage, for which reason it could not be made into Dolsan leaf mustard kimchi. These results could be recommended as the optimal salting conditions and storage time of salted Dolsan leaf mustard for making kimchi.

Design and Implementation of Service Model for Tailored Residential Space based on 3D Cadastral Information (3차원 지적정보 기반 맞춤형 주거 공간정보 서비스 모델 개발)

  • Bae, Sang Keun;Shin, Yun Ho;Lee, Seong Gyu;Joo, Yong Jin
    • Spatial Information Research
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    • v.23 no.2
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    • pp.49-57
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    • 2015
  • Recently, Through the linkage and opening, the fusion of the spatial information, it is necessary for productive ecosystem to provide a variety of information and to increase the civil use. Depending on the economic growth, demand for quality of life and well-being has been on the increase. Spatial information service contents for the public convenience has emerged to solve the problem such as health, safety, welfare and discomfort of daily life This study aims to implement search services for a tailored residence space through the three-dimensional data modeling on cadastral information. To achieve this goal, we established the requirements for deriving a registered object by investigating recent trend with respect to existing cadastral data model and defined property and relationship. Focusing on Songpa-gu, Jamsil station in Seoul, we implemented search services for a tailored residence space for three-dimensional right analysis in conjunction with residential and commercial complex building. As a result, we derived a way to supply 3D cadastre information through open platforms (VWorld) and to represent efficiently, which is able to improve the quality of spatial information service contents for the public convenience as well as to widen utilization of information.

Analysis of Convergent Factors Related to Job Satisfaction among Hospital Administrative Staff (병원행정직의 직무만족도와 관련된 융복합적 요인 분석)

  • Kim, Seung-Hee;Bae, Sang-Yun
    • Journal of Digital Convergence
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    • v.15 no.4
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    • pp.365-375
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    • 2017
  • This study is executed to investigate convergent factors to Job Satisfaction(JS) among Hospital Administrative Staff(HAS). The survey was administered to 221 staff from 11 general hospitals located in Jeonbuk area from Nov. 1st, 2016 to Jan. 31st, 2017. The structured self-administered questionaries were used. The hierarchical multiple regression analysis shows the following results. The JS of respondents turned out to be significantly higher in following groups: a group without work shift, a group with more employees, a group in which self efficacy is higher, a group in which skill variety in job characteristics is higher, a group in which interpersonal conflict and lack of reward in occupational stress are lower. The results show explanatory power of 61.0%. The results of the study indicate that the efforts, to increase self efficacy, and to manage job characteristics and occupational stress, are required to improve the JS among HAS. The results are expected to be useful for the program and human resource management to related to the JS among HAS. In the following study, the analysis of structural equation modeling about additional factors of the JS among HAS will be needed.