• Title/Summary/Keyword: 바이오 기능성

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Laboratory experiment on the adjustment processes of channel by weir removal (보 철거에 의한 하도 적응과정의 실험적 분석)

  • Kim, Gi Jung;Jang, Chang-Lae
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.401-405
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    • 2016
  • 중소하천에 기능을 상실한 하천 횡단 수리구조물이 많이 설치되어 있으며, 수리구조물 상류와 하류에 흐름 및 유사의 이송에 대한 연속성을 차단하고, 하천 교란의 원인이 되고 있다. 또한 사회적으로 수리구조물의 기능을 개선하거나 철거하여 하천복원의 필요성이 제기되고 있다. 따라서 본 연구에서는 실내실험을 통해 하천횡단 수리구조물에 의하여 형성된 상류의 지형이 하류에 미치는 영향을 분석하였다. 흐름이 하천횡단 수리구조물을 월류하면서 직하류에 세굴이 발생하고, 상류에서 델타를 형성하면서 퇴적되었다. 상류에서는 사주가 형성되었으며, 하류의 지형변화에 영향을 주었다. 하천횡단 수리구조물의 상류에 형성된 델타는 하류로 일정하게 이동하고 있으며, 델타가 구조물에 도달하기 바로 직전에서 수리구조물하류의 세굴이 가장 깊게 나타났다. 수리구조물 철거 후, 상류에 퇴적된 토사는 흐름에 의하여 급격하게 하류로 유실되었다. 천급점은 상류로 이동하며, 두부침식을 일으켰다. 일정한 시간이 지난 후에 상류에서 유입되는 유사에 의하여 침식은 감소되었다. 시간이 지나면서 하류에서 교호사주의 형상을 유지하며, 평형상태를 유지하였다.

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Preparation and Evaluation of Poly(methylmethacrylate-co-trimethoxysilylpropylmethacrylate) Spheres Containing Whitening and Anti-wrinkle Agents (미백 및 주름개선 성분을 함유하는 Poly(methylmethacrylate-co-trimethoxysilylpropylmethacrylate) 구의 제조와 평가)

  • Jung, Taek-Kyu;Lim, Mi-Sun;Kim, Young-Back;Yoon, Kyung-Sup
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.1 s.55
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    • pp.35-44
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    • 2006
  • Recently, encapsulation studies have been tarried out to protect active agents using shell materials such as polymers, lipids, inorganic materials and the other protective materials. We have prepared copolymers of methylmethacrylate (MMA) and trimethoxysilylpropylmethacrylate (TMPMA), and the copolymers as shell materials were used for encapsulating active agents. Poly(MMA-co-TMPMA) spheres were very efficient for encapsulating active agents such as vitamin derivatives (such as retinol, retinyl palmitate, tocopheryl acetate and ascorbyl tetraisopalmitate) and oil soluble licorice extract etc. Mean diameters of poly(MMA-co-TMPMA) core-shell spheres containing active agents varied between about 0.1 to $10{\mu}m$ according to the experimental conditions. The loading amount of encapsulating active agents was 15 to 25% (w/w) and the loading yield was above 90%. The stability of active agents in poly(MMA-co-TMPMA) core-shell spheres prepared with an UV absorbing precursor increased by 25% compared with that of active agents in spheres prepared without an UV absorbing precursor.

Anti-obesity and Anti-diabetic Effects of the Fermented Ethanol Extracts from White Jelly Fungus (Tremella fuciformis Berk) with Lactobacillus rhamnosus BHN-LAB 76 (Lactobacillus rhamnosus BHN-LAB 76로 발효한 흰목이버섯 (Tremella fuciformis Berk) 추출물의 항비만 및 항당뇨 효과)

  • Yoon, Yeo-Cho;Kim, Byung-Hyuk;Kim, Jung-Gyu;Lee, Jun-Hyeong;Park, YeEun;Park, Hye-Suk;Hwang, Hak-Soo;Kwon, Gi-Seok;Lee, Jung-Bok
    • Microbiology and Biotechnology Letters
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    • v.47 no.3
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    • pp.323-331
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    • 2019
  • White jelly fungus (Tremella fuciformis Berk; TF) has been used as a traditional medicine in Asia; it is known to prevent hypertension, aging, cancer, and arteriosclerosis. This study aimed to investigate the anti-diabetic effects of fermented Tremella fuciformis Berk (FTF) ethanol extracts fermented with L. rhamnosus BHN-LAB 76. We show that FTF increases the ${\alpha}$-glucosidase inhibitory activity and suppress the adipogenesis of 3T3-L1 adipocytes. These inhibitory effects of FTF are accompanied by the regulation of the phosphorylation of AMPK, JNK, and Akt. These data demonstrate that FTF not only inhibits adipogenesis by affecting the adipogenic signaling, but also increases the anti-diabetic effects by regulating the insulin signaling pathway. Therefore, we suggest that the FTF can be used for developing functional food and cosmetics materials.

울진 3&4호기 CFMS 화면설계의 인간공학적 검토

  • 정광태;이용희
    • Proceedings of the ESK Conference
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    • 1996.10a
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    • pp.171-178
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    • 1996
  • CFMS(Critical Function Monitoring System)는 원자력발전소의 비상시에 운전원에게 보조장보를 제공하는 지원시스템이다. 본 연구에서는 원자력발전소 울진 3&4호기 CFMS의 화면설계에 대한 인간 공학적 검토를 수행하였다. CFMS에 대한 규제 및 법규를 만족시키는 것과 CFMS 화면설계가 운전원에게 편의성을 제공할 수 있는지에 대한 인간공학적 타당성 평가의 사례를 제시하고자 한다. 본 연구에서는 인간공학적 검토의 공식적인 체계를 설정하기 위하여, CFMS 설계에서 필요한 인간공학 업무를 규정하고 수행절차를 기술하는 인간공학 프로그램 계획 (Human Factors Engineering Program Plan; HFEPP)과 설계평가의 방법과 업무 내용을 기술하는 확인 및 검증 프로그램 계획(Human Factors Engineerign Verification and Validation Plan; HFE V&V Plan)을 개발하였다. CFMS 설계에 대한 인간공학적 확인 및 검증을 위하여 CFMS의 정보 가용성 (information availability)과 화면 적합성 (display suitability)을 확인하였다. 정보 가용성의 확인은 CFMS 설계 요건서에서 정의된 정보를 중심으로 한 필요정보의 목록과 CFMS 화면상에서 제공되는 정보의 목록을 비교함으로써 수행되었다. 화면 적합성의 확인은 검토항목 선정, 검토양식 개발, 전문가 검토, 실험검토 등의 과정을 통하여 수행되었다. 관련 규제 문건으로 부터 규제요건상 만족해야할 최소한의 검토항목을 선정하고 검토양식을 개발하였으며, 인간공학 전문가들의 주관적 평가를 통하 여 수행되었다. 또한 화면의 조작방식에 대한 상세검토를 수행하였다. 검토결과로부터 발견된 문제점들은 HED (Human Engineerign Discrepance) 목록으로 정리하여 설계에 반영하도록 하였다.로 마음의 안정감, 몸의 긴장 이완에 따른 건강 상태 유지, 수업 집중도 향상 등이 나타났다. 위와 같은 종합 적 분석 결과에 따라, 본 연구는 제조 현장의 생산성 향상 및 품질 향상과 연계하여 작업자의 작업 집중도 향상, 작업자의 육체적, 심리적 변화에 따른 생산성 및 품질 향상 변화 정도 등의 산업공학(인간공학) 제 분야의 여러 측면에서 연구 및 적용이 가능하리라 사료된다.l, 시험군:25.90$\pm$7.16mg/d1, 47% 감소)를 나타내었으며, 시험군의 AUC는 대조군에 비해 39% 감소하였고, 혈중 아세트알데히드의 농도는 투여 60분후 시험군(3.96$\pm$0.07nmo1/$m\ell$)이 대조군(6.45$\pm$0,64nmo1/$m\ell$)에 비해 유의성 있는 감소(39%)를 나타내었으며, 시험군의 AUC는 대조군에 비해 48% 감소하였다 한편, 시험관내 에탄올 대사 효소에 대한 바이오짐의 효과를 검색해본 결과 바이오짐(2.0 $\mu\textrm{g}$/assay)에 의해 Aldehyde dehydrogenase(1.5unit/assay)의 활성이 14% 증가되었다. 본 연구의 결과로 볼 때, 비지니스 및 바이오짐은 음주 후 상승된 혈중 에탄을 농도 및 아세트알데히드의 농도를 현저히 감소시키는 효과가 있었다.량 보호 관리, 도시 소공원 개발, 역사 문화 공원 조성, 하천 공간 복원, 공원 시설 기능 개선, 이용 프로그램 개발, 공원 관리 개선, 환경 피해 녹지의 회복, 도시 환경 림 조성, 녹지 기능 증진, 도시 자연 경관 보전, 공원 녹지체계 구성, 공원 녹지 공급 균형, 주변 환경 녹화, 가로 녹화의 17개 시책을 제안하였다. 이러한 정책사업의 원활한 추진을 위해서는 기존의 관주도의 일방적인 공원 녹지 행정이 아닌 시민의 참여를 통

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Development of Probiotic Products and Challenges (프로바이오틱 제품 개발 동향과 과제)

  • Seo, Jae-Gu;Lee, Gwa-Soo;Kim, Jin-Eung;Chung, Myung-Jun
    • KSBB Journal
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    • v.25 no.4
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    • pp.303-310
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    • 2010
  • Probiotics beneficially affect the health of the host via various mechanisms in the intestine. Recent developments in probiotic products have mainly been made to maximize probiotic effects in human. In this regard, probiotic products containing doubly coated or encapsulated cells, multi-species probiotics, or high viable cell number (1010 viable cells/gram or more) have been developed and are already available in the market. Until now, the majority of probiotics contain live cells but little attention has been paid to other alternative products such as heat-killed cell or bacteriocin-containing ones, which could have broad applications due to advantages over live cell-based probiotics, such as safety and stability. In addition, genetically engineered lactic acid bacteria could be of great importance in the field of alimentary health if they are carefully designed for biological safety. Although a number of probiotics are marketed by claiming health benefits, regulations for health claims will be more stringent. Therefore sufficient scientific and clinical evidences supporting the safety and efficacy of the potential probiotic strain will be required by the regulatory authority for a health claim, which thus may have a huge impact on the future probiotic market.

An Improvement of Function Point Models for Software Cost Estimation (소프트웨어 비용산정을 위한 기능점수 모형 개선 연구)

  • Kim, Hyeon-Su
    • The Transactions of the Korea Information Processing Society
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    • v.6 no.9
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    • pp.2403-2413
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    • 1999
  • There is a strong need to develop a software cost estimation model on economic value perspective. The objective of this research is to improve current software cost estimation method on economic value perspective. We reviewed domestic and foreign researches and practices on software cost estimation with function point method, and derived promising alternative models. Pilot simulation was performed with real project data, and the probable best model was chosen. We collected data from 39 Korean companies, and assesed statistical significance of the model with those data. Empirical data shows that more practical model has better prediction accuracy. That is, the number of input and output modules, the number of tables, and the number of algorithms are chosen to be best set of functions. There exists strong correlation between the calculated function points and project effort. And, the revised set of technical complexity factors and evaluation guidelines show practical usefulness. We suggest that the above result be incorporated in a new improved guideline for software cost estimation. By adopting the results of this research to the guideline, we expect that technology innovation will be expedited, and that overall productivity of software industry will be increased.

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Dual Coating Improves the Survival of Probiotic Bifidobacterium Strains during Exposure to Simulated Gastro-Intestinal Conditions (위장관내 조건에서 이중코팅 처리 된 프로바이오틱 비피도박테리움의 생존력 향상)

  • Kang, Joo Yeon;Lee, Do Kyung;Park, Jae Eun;Kim, Min Ji;Lee, Joong-Su;Seo, Jae-Gu;Chung, Myung Jun;Shin, Hea Soon;Ha, Nam Joo
    • Korean Journal of Microbiology
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    • v.49 no.3
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    • pp.275-281
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    • 2013
  • Probiotics have been reported to benefit human health by modulating immunity, lowering cholesterol, improving lactose tolerance, and preventing some cancer. Once ingested, probiotic microorganisms have to survive harsh conditions such as low pH, protease-rich condition, and bile salts during their passage through the gastro-intestinal (GI) tract colonize and proliferate to exert their probiotic effects. The dual coating technology, by which the bacteria are doubly coated with peptides and polysaccharides in consecutive order, was developed to protect the ingested bacteria from the harsh conditions. The aim of the study was to evaluate the viable stability of a doubly coated blend of four species of Bifidobacterium by comparing its bile/acid resistance and heat viability in vitro with that of the non-coated blend. After challenges with acid, bile salts, heat, and viable cell counts (VVCs) of the dual coated and non-coated blend were determined by cultivation on agar plates or flow cytometric measurement after being stain with the BacLigtht kit$^{TM}$. The results showed that the dual coated blend was much higher resistant to the acidic or bile salt condition than the non-coated blend and heat viability was also higher, indicating that the dual coating can improve the survival of probiotic bacteria during their transit through the GI tract after consumption.

Relationship between Exercising Activity, Muscle Mass, Muscular Strength and Cognitive Function in the Elderly (노인의 운동참여, 근육량, 근력 및 인지기능과의 관련성)

  • Choi, Jae-won;Yoo, Ha-Na;Lee, Hyun-Woo;Kang, Sung-Goo;Jung, Hye-Yeon
    • Journal of the Korea Convergence Society
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    • v.9 no.5
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    • pp.219-229
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    • 2018
  • The purpose of this study was to investigate the relationship among Exercising Activity, muscle mass, Muscular strength and cognitive function of 274 elderly people aged 65 years and older living in Seoul and Gyeonggi-do As for the data collection methods, were measured the Exercising Activity, muscle mass and muscular strength and the Korean version of Mini Mental State Examination(MMSE-K) and digit span test were measured. The results are as follows First, there was a statistically significant correlation between Exercising activity, muscle mass, muscular strength, and cognitive function of the elderly. Second, Exercising activity of the elderly showed a positive (+) influence on muscle mass, muscular strength, and cognitive function. Third, the muscle mass of the elderly showed a statistically significant (+) influence on muscular strength and cognitive function. Fourth, the strength of the elderly showed a positive (+) influence on cognitive function.

Development of High Performance Nanocomposites using Functionalized Plant Oil Resins (식물성오일 레진을 이용한 고기능성 나노 복합재료의 개발)

  • Han, Song-Yi;Jung, Young-Hee;Oh, Jeong-Seok;Kaang, Shin-Young;Hong, Chang-Kook
    • Elastomers and Composites
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    • v.47 no.1
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    • pp.2-8
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    • 2012
  • In this study, in order to develop renewable bio-based nanocomposites, multi-functional nanocomposites from soybean resins (AESO, MAESO) and nanoclay were prepared. Photoelectrodes for environmental friendly dye-sensitized solar cell using soybean resin were also prepared. Organo-modified nanoclay was directly dispersed in functionalized soybean resins after mixing with styrene as a comonomer and radical initiator was used to copolymerize the nanocomposites. The observed morphology was a mixture of intercalated/exfoliated structure and the physical properties were improved by adding nanoclay. A nanocomposite using MAESO, which added COOH functional group to the soybean resin, showed better dispersibility than AESO composites. Ultrasonic treatment of the nanocomposites also improved the physical properties. Nanoporous $TiO_2$ photoelectrode was also prepared using soybean resins as a binder, after acid-treatment of $TiO_2$ surface using nitric acid. Dye-sensitized solar cells were prepared after adsorbing dye molecules on it. The $TiO_2$ photoelectrode prepared using soybean binder had high current density because of increased surface area by improved dispersibility. The photoelectrochemical properties and conversion efficiency of the solar cell were significantly improved using the soybean binder.

Supporting Service Continuity in Ubiquitous Network Environment with IMS Extension (IMS 확장을 통한 유비쿼터스 네트워크 환경에서의 서비스 연속성 지원)

  • Yim, Jong-Choul;Bae, Hyun-Joo;Kim, Sang-Ha
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37B no.12
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    • pp.1148-1159
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    • 2012
  • It is of great significance in the NGN - which supports a ubiquitous network environment in which users can use multiple devices and all the devices are connected to networks - to support the terminal mobility as well as service continuity. The IMS architecture, which is considered as session control layer in the NGN, exists to support a wide range of advanced new services in addition to the traditional voice and data connectivity offerings of "old" telecommunications. The recent IMS specification also defines IUT (Inter UE Session Transfer) functionality in order to support service continuity in the NGN. However, service continuity in IMS has a limitation that two terminals involved in session transfer should belong to the same user. In this paper, we proposed a new device discovery mechanism for IMS and extended UEs with a few capabilities to overcome some of IMS's limitations. We also analysed how much overhead of the proposed method in terms of signaling cost will be.