• Journal of the Korea Society of Computer and Information
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• v.17 no.4
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• pp.121-127
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• 2012

Biometric technology has been proposed as a new means to replace conventional PIN or password because it is hard to be lost and has the low possibility of illegal use. However, unlike a PIN or password, there is no way to modify the exposure if it is exposed and used illegally. To solve the problems, we propose to apply OTP using biometric information to mobile devices for more secure and adaptable authentication. In this paper, we propose a secure framework for delivering biometric information as mobile OTP to the server (TTP) and compared this paper with existed methods about security and performance.

• Proceedings of the Korea Contents Association Conference
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• 2015.05a
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• pp.231-232
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• 2015

최근 유전체학, NGS(Next Generation Sequencing) 기술, IT/NT 장비의 발전 등에 따라 방대한 양의 바이오-메디컬 데이터가 생산되고, 이에 따라 빅데이터를 활용한 헬스케어 산업이 급속히 발달하고 있으며, 이와 관련된 빅데이터 기술은 국민의 건강 증대와 건강한 고령 삶을 제공하는 핵심 기술로 급부상하고 있다. 패스웨이는 단백질, 유전자, 세포 등의 생체적 요소 간의 역학관계 혹은 상호작용 등을 네트워크 형식으로 표현한 생물학적 심층지식으로, 바이오-메디컬 빅데이터 분석에 있어서 널리 활용되고 있다. 하지만 패스웨이는 매우 다양한 형태를 갖고 용량이 매우 큰 빅데이터로 이를 분석하는데 많은 시간이 소요된다. 그래서 본 논문에서는 세계적으로 가장 우수하고 방대한 양의 패스웨이를 제공하는 KEGG 패스웨이 데이터베이스로부터 사용자가 관심 갖는 패스웨이만을 자동 수집하고 패스웨이 간 계층구조를 기반으로 네트워크를 구성 후, 해당 패스웨이 네트워크에 대한 클러스터링과 핵심 패스웨이 선정을 통해 패스웨이 간의 역학관계 또는 상호작용을 직관적으로 분석할 수 시스템을 제안했다.

• Journal of the Korea Society of Computer and Information
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• v.20 no.1
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• pp.143-151
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• 2015

Biometric technology has been proposed as a new means to replace conventional PIN or password because it is hard to be lost and has the low possibility of illegal use. However, unlike a PIN, password, and personal information there is no way to modify the exposure if it is exposed and used illegally. Therefore, the existing single modality with single biometrics is critical when it expose. However in this paper, we use a multi-modality and multi-biometrics to authenticate between users and TTP or between users and financial institutions. Thereby, we propose a more reliable method and compared this paper with existed methods about security and performance in this paper.

• Journal of KIISE:Software and Applications
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• v.31 no.3
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• pp.343-352
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• 2004

Recently, the information processing of ever increasing bio-related data is becoming a very important issue. One of the main sources of these bio-data comes with the form of biopathways, which includes molecular transactions and processes that are part of biochemical systems. The information represented by biopathways includes various organic relations among its components. However, most of the current systems to represent biopathways have been initially developed without computer processing in mind, and hence suffer from inconsistencies and ambiguities. In this paper, we propose an improved notation, called UniPath, for clear and systematic representation of biopathways. The proposed system is designed to provide a unified representation of metabolic and regulatory pathways. We also designed and implemented a graphic editor for UniPath to draw biopathwavs map according to the proposed notation. The graphic editor is designed so that biopathway data can be easily transformed into XML format.

• The Journal of the Korea Contents Association
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• v.14 no.11
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• pp.467-475
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• 2014

With the development of genomics, wearable device and IT/NT, a vast amount of bio-medical data are generated recently. Also, healthcare industries based on big-data are booming and big-data technology based on bio-medical data is rising rapidly as a core technology for improving the national health and aged society. A pathway is the biological deep knowledge that represents the relations of dynamics and interaction among proteins, genes and cells by a network. A pathway is wildly being used as an important part of a bio-medical big-data analysis. However, a pathway analysis requires a lot of time and effort because a pathway is very diverse and high volume. Also, multidimensional analysis systems for various pathways are nonexistent even now. In this paper, we proposed a pathway analysis system that collects user interest pathways from KEGG pathway database that supports the most widely used pathways, constructs a network based on a hierarchy structure of pathways and analyzes the relations of dynamics and interaction among pathways by clustering and selecting core pathways from the network. Finally, to verify the superiority of our pathway analysis system, we evaluate the performance of our system in various experiments.

• The Journal of the Korea Contents Association
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• v.12 no.2
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• pp.69-77
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• 2012

In the case of the password-based PKI technology, because it protects by using the password which is easy that user memorizes the private key, he has the problem about the password exposure. In addition, in the system of electronic bidding, the illegal use using the authentic certificate of the others increases. Recently, in order to solve this problem, the research about the PKI technology using the biometrics is actively progressed. If the bio information which the user inputs for the bio authentication is converted to the template, the digest access authentication in which the security is strengthened than the existing authentication technology can be built. Therefore, in this paper, we had designed and developed the system of electronic bidding which it uses the most widely used fingerprint information in the biometrics, it stores the user fingerprint information and certificate in the fingerprint security token and can authenticate the user. In case of using the system of electronic bidding of the public key infrastructure using the fingerprint information proposed in this paper the agent bid problem that it uses the certificate of the others in not only user authentication intensification but also system of electronic bidding can be concluded.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.11a
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• pp.690-692
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• 2022

기존의 질병 관련 연구들은 대부분 유의미하게 변화되는 유전자들을 찾아내고(Differentially Expressed Genes, DEGs), 이들이 연관된 생물학적 패스웨이(biological pathway)를 찾아내는 방향으로 이루어졌다. 더불어 miRNA(microRNA)가 많은 mRNA 의 발현을 조절하며, 실제 면역, 대사 및 세포 사멸을 포함한 여러 필수 생리학적 및 질병에 매우 중요한 역할을 한다고 밝혀지며, 바이오 마커로써의 miRNA 를 찾아내고자 하는 연구가 활발히 진행되기 시작하였다. 하지만 mRNA 나 miRNA 의 독립적인 연구만으로는 명확한 질병과의 연관성이나 기능을 이해하기에는 어려움이 있다. 따라서 본 연구에서는 질병 상태에서 유의미하게 변화되는 miRNA 와 이러한 miRNA 에 의해 조절되는 mRNA 를 함께 고려하여 분석함으로써, 실제 질병의 발병 원인이 되는 생물학적 패스웨이나 메커니즘을 밝히고자 하였다. 또한, miRNA 와 mRNA 의 연관성을 찾기 위해, PPI(protein-protein interaction) 네트워크에 기반을 둔 RWR(Random Walk with Restart Algorithm)를 적용하여, 직접적 연관성뿐 아니라, 유전자 간의 숨겨진 간접적인 패스웨이를 고려하여 분석하기 위한 웹 기반 시스템을 개발하였다. 이 시스템은 mRNA-miRNA 를 함께 고려한 통합 분석을 통해 숨겨진 질병의 메커니즘을 이해하고 치료 방법을 찾아내는 데 크게 공헌할 것이다.

• Proceedings of the Korea Contents Association Conference
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• 2014.11a
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• pp.49-50
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• 2014

바이오인식 기술은 기존의 패스워드나 PIN을 대체할 수 있는 새로운 수단이지만 바이오인식 기술은 한번 도용이 되면 기존의 수단과 달리 수정할 방법이 없으므로 바이오인식 정보를 안전하게 신뢰하는 제3의 장치에 등록하는 방법을 제안한다.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.47 no.5
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• pp.17-24
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• 2010

Recently the study of identifying bio-markers for disease diagnosis and prognosis has been actively performed. In particular, lots of attentions have been paid to the finding of pathway gene-sets differentially expressed in disease patients rather than the finding of individual gene markers. In this paper we propose a novel method to identify disease-related pathway gene-sets based on time-series microarray data. For this purpose, we firstly compute individual gene scores by the using maSigPro (microarray Significant Profiles) and then arrange all the genes in the decreasing order of the corresponding gene scores. The rank of each gene in the entire list is used to evaluate the statistical significance of candidate gene-sets with Wilcoxson rank sum test. For the generation of candidate gene-sets, MSigDB (Molecular Signatures Database) pathway information has been employed. The experiment was conducted with prostate cancer time-series microarray data and the results showed the usefulness of the proposed method by correctly identifying 6 out of 7 biological pathways already known as being actually related to prostate cancer.

• Journal of the Korea Convergence Society
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• v.8 no.2
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• pp.9-14
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• 2017

A fingerprint is unique to each person and can be represented as a digital form. As the fingerprint is the part of human body, fingerprint recognition is much more easy to use and secure rather than using password or resident card for user authentication. In addition, as the newly released smart phones have built-in camera and fingerprint sensors, the demand for biometric authentication is increasing rapidly. But, the drawback is that the fingerprint can be counterfeited easily and if it's exposed to the hacker, it cannot be reused. Thus, the original fingerprint template should be transformed for registration and authentication purposes. Existing transformation functions use passcode to transform the original template to the cancelable form. Additional module is needed to input the passcode, so it requires more cost and lowers the usability. In this paper, we propose biometric authentication scheme that is economic and easy to use. The proposed scheme is consisted of cancelable biometric template creation, registration and user authentication protocols, and can control several security levels by configuring the number of fingerprints and scan times. We also analyzed that our scheme is secure against the brute-force attack and the active attacks.