• Title/Summary/Keyword: 모 표피

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Stevens-Johnson Syndrome : A Case Report (스티븐 존슨 증후군 : 증례보고)

  • Song, Yongho;Lee, Nanyoung;Lee, Sangho;Jih, Myeongkwan;Lim, Yujin;Yoon, Youngmi
    • Journal of the korean academy of Pediatric Dentistry
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    • v.44 no.4
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    • pp.455-460
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    • 2017
  • Stevens-Johnson syndrome (SJS), an extremely severe acute hypersensitivity reaction, causes extensive necrosis on the skin and the mucous membrane. SJS is a disease of unknown cause that can occur in all age groups. It is thought to be caused by drug allergy or induced by bacterial infection. Epidermal surface invasion of less than 10 percent is called SJS, and invasion of more than 30 percent is called toxic epidermal necrolysis. Although it is rare with an incidence of 1 - 2 cases per million people per year, it has effects on tooth development and therefore on children who are in a growth phase. The purpose of this case report is to examine the effect of SJS on tooth development in children. In general, eruption of the upper and lower 1st molars and lower central incisors starts at 6 - 7 years of age. Root development also occurs at this time. In the case reported here, SJS occurred in a 6-year-old patient. Although the patient's SJS was completely cured, he still suffers from aftereffects. Developmental abnormalities in the patient's teeth were observed only in teeth for which root development had been completed at the time. The purpose of this case report is to illustrate how to diagnose such systemic diseases by intra-oral features and to recognize and resolve tooth development problems associated with the disease.

Total Dose Effect on Normal Skin of Hybrid Mice by Conventional Fractionated Irradiation (고식적 분할조사시 방사선의 전조사량이 잡종 마우스의 정상피부에 미치는 병리조직학적 변화)

  • Jung, Kyung-Hee;Kim, Myung-Se;Choi, Won-Hee
    • Journal of Yeungnam Medical Science
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    • v.3 no.1
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    • pp.261-267
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    • 1986
  • Development of supervoltage treatment machine may minimize skin reaction by skin-sparing effect, but skin damage is still one of "the dose limiting factor" in radiation therapy. In spite of these importance, systemic histopathologic studies of skin in similar conditions which used in clinical treatment has not been performed so far. 60mice were irradiated with conventional fraction ($200{\times}5/wk$) and whole abdominal field ($2{\times}3cm$, from symphysis pubis to xyphoid process). Used machine was 250KV, 24mA, orthovoltage x-ray machine. Histopathological changes of acute skin reaction at the level of total irradiation dose were analyzed and the possible mechanism of later chronic changes were investigated. Obtained results are as follows: 1. In 1,000 rad irradiated group, only mild epidermal edema is noted. 2. In 2,000 rad irradiated group, slightly decreased number and size of hair follicles and appendages, dermal edema and scanty infiltration of inflammatory cells are visible. 3. In 3,000 rad irradiated group, marked increased capillary congestion and prominant infiltration of inflammatory cells are observed. 4. In 4,000 rad irradiated group, vascular wall thickening with proliferation of endothelial cells are prominant. Dermal thinning and hyalinization are newly developed. 5. In 5,000 rad irradiated group, complete desquamation of epidermis is not seen, despite of acceleration of all above mentioned changes.

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The Efficacy of Oral Low Molecular Weight Collagen Peptide for Skin Recovery after Fractional Photothermolysis Laser Treatment (Fractional Photothermolysis 치료 후 피부회복 촉진에 미치는 경구용 저분자 콜라겐 펩타이드의 효과)

  • Kim, In Su;Choi, Sun Young;Kim, Byung Gyu;Kim, Jeong Kee;Kim, Eun Joo;Kim, Beom Joon;Kim, Myeung Nam
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.38 no.4
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    • pp.321-326
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    • 2012
  • Recent studies have revealed that collagen peptide plays a protective role on skin by improving the activity of antioxidants and acts as an inducer of skin regeneration. To evaluate the efficacy of low molecular weight collagen peptide for skin recovery after non-ablative 1550 nm fractional photothermolysis laser. 10 volunteers were randomly divided into two groups. Both control and experimental groups received fractional photothermolysis treatment. In the experimental group, 5 subjects received oral collagen peptide 1,000 mg/day for 8 weeks. Before and after the treatment, we measured elastic recovery of skin, transepidermal water loss (TEWL) and erythema index (EI) for each patients. The evaluation of clinical results showed that elastic recovery of skin is higher in the experimental group than the control group (p < 0.05). TEWL have no significancy between two groups and erythema rapidly disappeared in the experimental group. On the quartile grading scale, the mean patient satisfaction 4 weeks after the fractional photothermolysis treatment was 2.0 in experimental group and 1.2 in control group. The low molecular weight collagen peptide appears to be an effective conservative therapy for skin recovery after non-ablative 1550 nm fractional photothermolysis treatment.

Potential for Application of Microhistological Analysis in Diet Plants of Korean Water Deer($Hydropotes$ $inermis$) (한국에 서식하는 고라니($Hydropotes$ $inermis$) 먹이식물의 미세조직분석법 적용 가능성 연구)

  • Kim, Eui-Kyeong;Park, Yung-Chul;Kim, Won-Myeong;Kim, Jong-Kuk
    • Korean Journal of Environment and Ecology
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    • v.26 no.2
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    • pp.192-199
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    • 2012
  • This study was to evaluate the application of microhistological analysis to collect information on food materials of korean water deer from september to October 2006. For microhistological analysis we extracted type-materials of 4 plant species ($Ipomoea$ $batatas$, $Rubus$ $coreanus$, $Glycine$ $max$, and $Pueraria$ $thunbergiana$) from fecal pellets of korean water deer ($Hydropotes$ $inermis$) and then made preparations of the fecal materials for microscopic analysis. The fecal preparations were compared with reference preparation under the microscope. In microscopic analysis of fecal preparations, we could identify the four plant species by the followings: tip shape and morphology of trichomes, epidermal cell, morphological composition and shape of stomatal apparatus, arrangement of long-cell, and distribution of crystals in cells. According to the comparisons of the preparations, the morphology of trichome, epidermal cell and stomata are similar between both preparations of the fecal pellets and the references, respectively. This methodology will contribute to understanding feeding behavior and behavioural ecology by climate change of other hervibores as well as korean water deers.

Grape Pruning Stem Extract (GPSE) Suppresses Allergy and Skin Proliferation Inhibition against UVB Induced Skin Damage (포도전정가지 추출물이 UVB에 유도된 피부 손상에 대한 알레르기와 피부증식 억제효과)

  • Kim, Joung-Hee;Kim, Dae Hwan;Kim, Keuk-Jun
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.329-336
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    • 2017
  • This study examined the effects of polyphenols in grape pruning stem extracts (GPSE) using grape stems discarded after harvest. The inhibitory effects on allergy, proliferation, and apoptosis in UVB-induced HR-1 hairless mice were analyzed. The applicability as a material for functional food and functional cosmetics was evaluated. The contents of the active ingredients of GPSE were analyzed by HPLC. After UVB irradiation on the dermis of HR-1 hairless mice, the number of mast cells was determined by toluidine blue staining to confirm that the skin allergic reaction was caused by GPSE. The results were similar to the normal group in the group applied GPSE, and there was no allergic reaction in the GPSE application group and a significant decreased compared to the sun cream control. PCNA immunohistochemical staining of the epidermal proliferation factor had an inhibitory effect on epidermal epithelial cell proliferation in all concentrations of GPSE and serum base mixture as an average of 42% compared to the control group. The mixture of GPSE and serum base suppressed the apoptosis inhibition rate by 27% on average compared to the control. These results confirmed the inhibitory effects GPSE on the allergic, proliferation, and apoptosis activities by with a serum base on UVB-induced skin damage. GPSE is a functional ingredient with potential skin protection effects, and has a high utilization as an ingredient for functional cosmetics.

Effects of Artificial Acid Mist on Leaf Injury and Surface Wettability of Several Broad-Leaved Species (인공산성연무(人工酸性煙霧)의 처리(處理)가 몇 활엽수종(闊葉樹種)의 엽피해(葉被害)와 엽표면(葉表面)의 친수성(親水性)에 미치는 영향(影響))

  • Kim, Gab Tae;Um, Tae Won
    • Journal of Korean Society of Forest Science
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    • v.85 no.4
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    • pp.577-585
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    • 1996
  • To seek effective methods for evaluating air pollution and acid rain injury, artificial acid mist(pH 2.5, 3.5 and 4.5) and ground water(pH 6.5) were treated on the potted seedlings of Ligustrum obtusifolium, Cercis chinensis, Hibiscus syriacus and Sophora japonica. Leaf chlorophyll contents, characteristics of leaf-injury, wettability-measurement of diameter of water-droplets on the leaf surface-among treatments were investigated. The results were summarized as follows. 1. Chlorophyll contents of Ligustrum obtusifolium and Hibiscus syriacus measured on June 3 were highest in pH 2.5 plot, but those of Cercis chinensis and Sophora japonica were relatively low level. Chlorophyll contents of Ligustrum obtusifolium measured on August 24 was highest in pH 2.5 plot, but those of Cercis chinensis, Hibiscus syriacus and Sophora japonica were highest in the control. 2. Changes of chlorophyll contents with acid mist treatments were differed among tree species. 3. For all the tested species, leaf injury(injured leaf number and rate, and injured leaf area) increased with decreasing pH levels of acid mist. 4. Leaf tissue injury seemed to be related with the wettability of the leaf surface. Measurement of diameter of water-droplets on the leaf surface might be useful criteria for acid rain or acid mist injury for the glabrous leaved species, such as, Cercis chinensis, Sophora japonica, etc.

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The taxonomic implication of leaf anatomy in tribe Sorbarieae (Spiraeoideae: Rosaceae) (쉬땅나무족(Sorbarieae Rydb., 장미과) 잎의 해부학적 형질 및 분류학적 유용성)

  • Song, Jun-Ho;Hong, Suk-Pyo
    • Korean Journal of Plant Taxonomy
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    • v.44 no.2
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    • pp.119-131
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    • 2014
  • A comparative study of leaf anatomy in tribe Sorbarieae (Adenostoma, Chamaebatiaria, Sorbaria, Spiraeanthus) including one related genus Lyonothamnus was carried out using light microscopy. Anatomical characteristics of the leaf blade and midrib were described and taxonomically evaluated. The anatomical characters which described in this study are as follows: thickness of leaf midrib, blade in cross section, cuticle, epidermal cell, stoma, trichome, mesophyll, crystal, main vasculature type. All features were compared and the vascular patterns of midrib were distinguished two types. - Type 1: Trace tripartite (Adenostoma), Type 2: Trace continuous, subtype 2A: flat arc (Chamaebatiaria, Spiraeanthus), subtype 2B: U-shape arc (Lyonothamnus, Sorbaria). In conclusion, some of leaf anatomical characters (e.g., cuticle, epidermal cell, trichome, mesophyll, main vasculature type) can be useful for diagnostic features. Hypostomatic type, dorsiventral mesophyll, Ushape vasculature type would constitute a major characters for genus Sorbaria in Sorbarieae. The detailed anatomical description of studied taxa is provided, and its systematic importance is also briefly discussed.

Esterase Isozymes of Beet Armyworm, Spodoptera exigua(H bner), with Development and Tissues (발육 및 조직에 따른 파밤나방(Spodoptera exigua (H bner)) 에스테라제 동위효소)

  • 강성영;김용균
    • Korean journal of applied entomology
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    • v.37 no.2
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    • pp.179-185
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    • 1998
  • The effect of physiological factors of beet armyworm, Spodoptera exigua (Hubner), on esterase variation was analyzed by comparing electrophoretic esterase isozymes. Each esterase isozyme was also characterized by substrate and inhibitor specificities. A total of 28 esterase isozymes were separated on 10% nondenaturing polycarylamide gel electrophoresis (PAGE). These isozymes were denoted from El to E28 according to cathodal migration distances. There was a variation in esterase isozymes among developmental stages. Larvae and pupae had more isozymes than did adults. Eggs had only eight isozymes. The isozymes of El and E2 were specific only in the first instar larvae. Esterases also showed variation according to different tissues. More kinds of esterase isozymes were found in epidermis and gut tissues than in hemolymph and fat body. Some isozymes were specific in epidermis (from El to E6), gut (E10, El 1, E25, E26, and E27), and hemolymph (E18). Among 10 naphthyl esters, a-naphthyl propionate was the most reactive substrate to the esterase isozymes. The isozymes were classified into cholinesterases (El0 and E24), arylesterases (E4, E9, E17, E19, E21, and E23), and carboxylesterases (the others) on the basis of inhibition by the esterase inhibitors-eserine, dichlorovos, moncrotophos, and paraoxon.

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Changes in Body Temperature of Piglets in a Day (자돈의 일중 체온변화에 관한 연구)

  • Yi, One-Hyeon;Jeong, Wang-Yong;Lee, Sang-Cheol;Lee, Sang-Rak
    • Journal of Animal Environmental Science
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    • v.18 no.2
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    • pp.91-94
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    • 2012
  • This study was conducted to develop an algorithm for determination of abnormal body temperature in piglets through skin and core temperature database at normal condition. 5 piglets (mean BW : 46 kg) were employed for the experiment. They were adapted in the individual metabolism cage set at $22.5{\pm}2.0^{\circ}C$ of room temperature for 2 weeks before the measurement of body temperature. Ear, neck, head and subcutaneous neck temperature (as core temperature) of piglets were measured for every 1 minute during 30 consecutive days through 1mm k-type thermocouple wire and NI-devices (National Instruments Corporation, Austin, Texas, USA). Body temperature data were accumulated and integrated into the 1 day unit. Change of daily mean skin and core body temperatures in piglets were lowest at around 06:00, highest at around 14:00 and gradually decreased until the day after 06:00. Each skin temperatures were varied with the measuring site and largely depended on the room temperature changes. Established database of skin and core body temperature in piglets through this study can be applied to develop an algorithm for monitoring and determining the abnormal condition of animal by using radio frequency identification.

Study of the Function of β-D-fructofuranosidase by Plant Histological Method (식물 조직학적 방법에 의한 β-D-fructofuranosidase의 기능 연구)

  • Donggiun Kim
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.4
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    • pp.587-592
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    • 2023
  • Plant growth is regulated by a variety of factors, including organic matter availability. Organic nutrients are carbohydrate molecules from photosynthetic products produced by tissues associated with carbon and energy fixation called "sources". These compounds flow through plant vascular bundles into non-photosynthetic or growing tissues called "sinks". Among these possible compounds, the disaccharide fructosyl glucose, sucrose, is the most representative. During the transport of sucrose, the pathway from the source to the sinks can include hydrolysis of sucrose into glucose and fructose derivatives or direct transfer of sucrose. Among the enzymes involved in this, β-D-fructofuranosidase is the most important. Soluble neutral β-D-fructofuranosidase, one of several isoenzymes, is located in intracellular protoplasts and helps plant cells metabolize sucrose to produce energy. In order to track the activity of this enzyme during the course of plant growth, histological methods were used for the most effective immunolocalization. As a result, the activity was higher in the phloem and epidermis than in the mesophyll tissue in the leaf. In the growing stem, activity was high in the phloem, epidermis, and cortex. The activity of the root, which is a sink tissue, was high in all parts, but especially the highest in the root tip part. It is thought that this is because it helps unloading of sucrose in sink tissues that require sucrose degradation and plays a role in hydrolysising sucrose.