• Journal of Life Science
• /
• v.27 no.5
• /
• pp.600-610
• /
• 2017

It was common that the classification of itching was classified into four categories according to the neurophysiological mechanisms of pruritoceptive itching, neuropathic itching, neurogenic itching and psychogenic itching. Recently it was classified by clinical criteria. The neurotransmission pathway of itch is divided into histamine-dependent pathway and histamine-independent pathway. Different receptors and neuropeptides act on each itch mediator. Itch mediators such as histamine, BAM8-22, and chloroquine are transmitted through the histamine-dependent pathway. Cowhage spicule, protease, and TSLP (Thymic stromal lymphopoietin) have been reported to be related to the histamine-independent pathway. These itch mediators, receptors, and neuropeptides are the targets of treatment for itching. Although itching and pain are typical noxious stimuli, and in the past, it was argued that two senses were transmitted through one noxious stimulus receptor. It has recently been shown that itching and pain have an independent neurotransmitter system and both neuronal systems inhibit each other. In addition, the mutual antagonism between itching and pain is explained by various mechanisms. Recently, many new mediators and receptors are being studied. The studies on histamine 4 receptor (H4 receptor) have been actively conducted. And the H4 receptors are expressed in immune cells such as T cells. The therapeutic agent for blocking the H4 receptor can inhibit the inflammatory reaction itself, which is important for the itching and chronicization. Understanding the underlying mechanisms of itching and studying new itch mediators will lead to the development of effective therapies, and this is what I think the itching study will go on.

• The Journal of the Convergence on Culture Technology
• /
• v.7 no.2
• /
• pp.275-280
• /
• 2021

This study began with the question of obtaining human resources through the promotion of outstanding resources of the Special Forces Officer and studied the following four promotion strategies: First, it is Facebook's promotional strategy medium. Second, it is a promotional strategy medium of YouTube. Third, it is a promotional strategy medium for blogs. Fourth, it is a public relations strategy medium for Web site. Furthermore, we would like to consider this study through four promotional strategies and cases of acquiring excellent foreign personnel in order to acquire excellent non-commissioned officers. Therefore, it is necessary to obtain excellent resources through promotional activities by utilizing strategic intermediaries for obtaining excellent resources from special forces. Ultimately, this study can provide fundamental implications for recruiting special forces officers for obtaining excellent resources by utilizing strategic intermediaries.

• Microbiology and Biotechnology Letters
• /
• v.35 no.1
• /
• pp.73-80
• /
• 2007

Biofilm media was equipped in two-compartmented wastewater treatment bioreactor which was separated by porcelain septum. DC 2.0 volt of electric potential was charged to anodic (oxidative) biofilm media (ABM) to induce oxidation potential but not to that of carbon (neutral) biofilm media (CBM) that was used for control test. Biofilm structure, biomass variation, Off variation and wastewater treatment efficiency in the bioreactor equipped with ABM (ABM-bioreactor) and CBM (CBM-bioreactor). Time-coursed variation of biofilm structure forming on surface of ABM and CBM was observed by scanning electron microscopy. The biofilm growing on ABM was dispersed on surface and was not completely covered the media but the biofilm growing on CBM was continuously increased and finally covered the media. The ORP of CBM was decreased to 100 mV, which was reciprocally proportional to the biomass growth. However, the ORP of ABM was about 800 mV, which was maintained during operation for about 60 days. The treatment efficiency of COD in the ABM bioreactor was 2 times higher than those in the CBM bioreactor. From these results, we proposed that electrochemical oxidation potential charged to biofilm media may inhibit formation of biofilm extremely condensed and activate bacterial cell metabolism.

• Communications of Mathematical Education
• /
• v.32 no.3
• /
• pp.407-433
• /
• 2018

In order to analyze textbooks from a discursive approach, the purpose of this study is to structuralize an analytic framework based on previous literature review and apply it to analyzing the meanings and their syntheses developed by words and visual mediators appeared in the definition of graph in first-year middle school textbooks. The discursive approach consists of the communicational approach developed by Sfard(2008) and the systemic functional linguistics developed by Halliday(1985/2004). In this study, ideational meta-functions for ideational meanings and interpersonal meta-functions for interpersonal meanings were employed to analyze the meanings produced by words and visual mediators in textbooks, whereas textual meta-functions for textual meanings were used for analyzing the synthesized relationships between words and visual mediators. Results show that first, density in mathematical discourse was very high and subjects in mathematical activities were ambiguous in the ideational meanings of words, and behavior aspect was more emphasized than thinking aspect in the interpersonal meanings of words which request student participations. In the case of ideational meanings of visual mediators, there was a lack of narrative diagrams, whereas there were qualitative differences in the case of offer. Second, there was a need for promoting a wide range of diverse synthetic relationships between words and visual mediators for developing enriched mathematical meanings through the varying uses like specification, explanation, similarity, and complement. These results are so important that they provide a new analytic framework from a discursive approach to textbook analysis because not only words, but also visual mediators are analyzed as tools for producing meanings in mathematics textbooks and their synthetic relationships are also examined.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2023.05a
• /
• pp.350-350
• /
• 2023

SCE-UA(Shuffled Complex Evolution-University Arizona)기법은 최적해 탐색 알고리즘으로 개념적 강우유출 모형(conceptual rainfall runoff model)의 보정을 위한 도구로 개발되었다. SCE-UA기법은 메타휴리스틱 방법의 일종으로 최적해를 구하기 위하여 여러번 목적함수 값을 계산해야 한다. 이 때 목적함수 계산 횟수와 해의 수렴과 관련된 제어 매개변수가 존재하며, 사용자가 적절한 값을 입력해주어야 한다. 이 연구에서는 SCE-UA와 관련된 제어 매개변수의 기능에 대해서 검토하였다. 그리고 집합체 수의 변화에 따라서 검사함수인 Ackley function의 전역해를 얼마나 잘 탐색하는지 검토하였다. 검토 결과 랜덤 시드에 따라서 전역해 탐색 결과가 달라졌으며, 집합체의 수가 증가할수록 목적함수 계산 횟수는 증가하는 경향을 나타내었다. 검사함수의 차원(결정 변수의 수)이 증가하면 전역해의 탐색률이 감소하며, 집합체의 수가 많아지면 전역해를 더 잘 찾는 경향이 나타나지만, 목적함수 계산 횟수는 더 많아지게 되는 것을 확인할 수 있었다. 2차원인 경우 집합체의 수가 7개 이상일 때 탐색 성공률은 90% 이상이 되었지만, 10차원인 경우 집합체의 수가 시험 최대값인 20개일 때의 전역해 탐색률은 37%에 그쳤다. 이 연구의 결과는 SCE-UA 기법의 설정 매개변수에 관한 기본 개념을 이해하고, 사용자가 설정 매개변수 선정 시에 활용할 수 있을 것이다.

• Explosives and Blasting
• /
• v.30 no.2
• /
• pp.43-51
• /
• 2012

The Demolition blasting has been applied for buildings and structures so far. In this study, however, a confined vessel blasting filled with water has been focused. A small amount of explosives were placed in a sealed vessel with water, perfect elastic body, supposed as a relay agent in it, and the blasting aspect was observed. Blasting pressure was standardized by Abel's equation of state. In result, if there was a relay agent in it, the pressure vessel was torn apart with smaller power than its tensile strength. If there was not, it needed 7.1~8.5 times as much power as the previous one, and the blasting pressure had not also affected the demolition and it had gone or vanished until it reached a certain point, In terms of pressure vessel made by steel, the elastic-plastic failure was took a place, and the first yield point happened along the welded area as a form of heating plastic failure we thought.

• Proceedings of the Optical Society of Korea Conference
• /
• 2000.08a
• /
• pp.222-223
• /
• 2000

지금까지 gold-coated 반사체, cusp-shaped 반사체, 복합 포물 반사체(CPC), 난반사 공동체 등 다양한 형태의 반사체가 횡펌핑을 이용한 Nd:YAG 레이저의 개발을 위하여 고안되어졌다. 횡여기되는 Nd:YAG 레이저의 광학적 효율은 반사체의 형태, 다이오드 레이저의 파장, Nd:YAG 결정의 지름, Nd$^3$의 도핑농도에 따라 영향을 받는다.$^{(1)}$ 본 연구에서는 고출력의 횡여기 Nd:YAG 레이저를 개발할 목적으로 광여기 공동으로 사용된 난반사 공동체의 내부지름과 레이저 매질인 Nd:YAG 결정의 흡수계수 등 매개변수를 변화시켜 흡수분포와 출력을 계산하였으며, 이러한 매개변수들이 기울기 효율에 미치는 영향을 수치 해석적으로 연구해 보았다. 광선추적법에서 사용한 매개변수 중에서 다이오드 레이저의 파장은 808 nm이고, 반사율은 90%이며, 여기 다이오드 출력은 1080 W이다. 난반사 공동체$^{(2)}$ 의 반사율은 95.7%이고, 결정의 투과율은 90%이며, 결정의 반지름은 2.5 mm이다. 사용된 여기 구조도는 그림 1과 같다. 여기헤드는 Nd:YAG 결정, 난반사 공동체, 그리고 3개의 360 W급 다이오드 어레이들로 구성되어 있다. (중략)

• 한국벤처창업학회:학술대회논문집
• /
• 2024.04a
• /
• pp.125-133
• /
• 2024

최근 국내에서는 인구감소에 따른 일부 지역소멸이 화두가 되고 있다. 대부분이 농촌지역으로 여러 가지 원인이 있으나, 원인 중의 하나로 농업경영체의 성과 미흡에 따른 소득향상의 어려움이 있기 때문이다. 이를 극복하기 위해 정부와 지자체에서는 다양한 정책을 수립하여 지속해서 지원하고 있지만 큰 성과를 내지 못하고 오히려 농엉경영체의 요구사항만 많아지고 있다. 본 연구의 목적은 경영자역량이 기업성과에 미치는 영향관계를 살펴보고 경영자역량과 기업성과 간에 있어 시장지향성이 매개역할을 하는지에 대해 분석하는데 있다. 본 연구에서는 농업경영체의 경영자역량을 독립면수로 하여 히위변수에 창의적역량, 네트워킹역량, 자기통제역량, 기술적역량을 선정하고 종속변수에는 기업성과를 매개변수로 시장지향성을 선정하고 연구를 진행하였다. 따라서 본 연구는 농업경영체의 경영자역량이 기업성과에 영향을 미칠 수 있고 시장지향성이 매개효과가 있을 것이라는 인과적 경로를 검증하고자 한다. 세계적인 불확실한 경제환경과 빠르게 변화되고 있는 국내 산업의 구조변화는 농업경영체들이 적응함에 있어 어려움이 존재하고 있는 상황에서 농촌에서 기업활동을 하고 있는 농업경영체 경영자역량의 주요 요인들을 설정하여 연구를 진행하였고 경영자들이 기업성과를 달성함에 있어 도움이 될 것이다.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.38 no.8
• /
• pp.677-685
• /
• 2014

A direct carbon fuel cell (DCFC) generates electricity directly by converting the chemical energy in coal. In particular, a DCFC system with a solid oxide electrolyte and molten carbonate anode media has been proposed by SRI. In this system, however, there are conflicting effects of temperature, which enhances the ion conductivity of the solid electrolyte and reactivity at the electrodes while causing a stability problem for the anode media. In this study, the effect of temperature on the stability of a carbon-carbonate mixture was investigated experimentally. TGA analysis was conducted under either nitrogen or carbon dioxide ambient for $Li_2CO_3$, $K_2CO_3$, and their mixtures with carbon black. The composition of the exit gas was also monitored during temperature elevation. A simplified reaction model was suggested by considering the decomposition of carbonates and the catalyzed Boudouard reactions. The suggested model could well explain both the measured weight loss of the mixture and the gas formation from it.

• 건강소식
• /
• v.9 no.11 s.84
• /
• pp.10-13
• /
• 1985

우리나라에 있어서도 여름 한철의 기온은 열대지역 못지않게 높고 덮다. 따라서 이 기간에는 온갖 질병이 얼마든지 발생할 수 있으며 만면 할 수 있다. 다만 여름철이 비교적 짧기 때문에 병원체나 매개체들의 활동과 번식이 제한을 받고 있을 뿐이다.