• KSBB Journal
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• v.8 no.5
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• pp.424-430
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• 1993

The anti-stress effect by the treatment of vitamin C was investigated in this study. The treatment of ascorbic acid in the presence of $Cu^{2+}$ion induced strong time- and dose-dependent degradation of hitamine, and also the addition of histamine accelerated time-dependent decomposition of ascorbic acid in vitro. The treatment of ascorbic acid in $ODS^{od}/_{od}$rats, which cannot synthesize ascorbic acid, significantly decreased the urinary histamine. The protreatment of ascorbic acid, dexamethasone and promethazine inhibited the lethal effect induced by immobilization stress, but that of dimethylsulfoxide did not. The addition of ascorbic and to a culture of spleen cells of $ODS^{od}/_{od}$rats significantly increased the Con A-dependent T lymphocyte proliferation.

• Journal of Digital Contents Society
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• v.11 no.2
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• pp.253-264
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• 2010

This study aimed to 1) analyze television drama text to examines how Korean television dramas represent alcohol drinking; 2) interview the actual drama audience to examine how they perceive drinking and whether or not their perception is influenced by the drama text. The author analyzed 60 drama episodes from 12 prime time shows that reached over 20% rating from 2008 to 2010. The result shows that drinking in dramas are portrayed as a solution to various kinds of personal and business problems, medium of romance, a tool for interpersonal communication that facilitates understanding and positive relationship. Female drinkers are prominent but their drinking is taking place under the patronage of male characters, which lead to the maintenance of patriarchal social relations. Interview findings show that the audience have strong motivation to imitate the glamourous lifestyles of leading characters in dramas. The findings strongly suggest observational learning was taking place, especially in the area where the viewers have no direct experience.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.10
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• pp.1499-1505
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• 2010

In general, magnetic abrasive polishing can be used to effectively produce a mirror-like surface; however, industrial applications of this process involve some unsolved problems. For example, the polishing efficiency is low, and the used abrasives have to be treated. In this study, which is aimed at solving these problems, a novel medium of silicone gel, consisting of ferromagnetic particles and abrasives, is developed, and the effect of this medium is assessed on the basis of Taguchi's experimental method. The workpiece is a tungsten carbide steel and the surface roughness after magnetic abrasive polishing using the silicone gel is evaluated.

• Archives of design research
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• v.18 no.1 s.59
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• pp.145-156
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• 2005

The gate of university can be the first impression of the University itself and most important advertising structure which is more than just a structure that people pass by. It can also be the medium that connects the outside with the inside of the campus. Therefore, many universities are willing to have a unique and symbolic gate of their own. Recently, university representatives have become interested in arranging external areas of the campus. At this respect, studying and researching university gates and surroundings facilities must be realized. We visited 104 different universities gates to research and survey people about what they think of the internal and external individuality of each gate. According to these researches we established a full data base of 24 types of classifications, 5 characteristic forms of each shapes, 8 forms of the symbolic characteristics of university gates and 10 surroundings facilities of the university gates.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.10
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• pp.118-127
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• 2014

DNA data storage refers to any technique for storing massive digital data in base sequence of DNA and has been recognized as the future storage medium recently. This paper presents an information hiding method for DNA data storage that the massive data is hidden in non-coding strand based on DNA steganography. Our method maps the encrypted data to the data base sequence using the numerical mapping table and then hides it in the non-coding strand using the key that consists of the seed and sector length. Therefore, our method can preserve the protein, extract the hidden data without the knowledge of host DNA sequence, and detect the position of mutation error. Experimental results verify that our method has more high data capacity than conventional methods and also detects the positions of mutation errors by the parity bases.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.3
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• pp.804-809
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• 2003

Kagam-bojungikgitang is the water extracts prepared from Ginseng Radix, Astragali Radix. Angelicae gigantis Radix, Astractylodis Rhizoma alba, Aurantii nobilis Pericarpium, Glycyrrhizae Radix, Artemisiae iwayomogii Herba, and Scutellariae Radix. This is a modified prescription of Bojungikgitang, which has been used for the treatment of indigestion, and immunological disease in oriental countries. In this study, the effects of Kagam-bojungikgitang and Bojungikgitang on the production of prostaglandin E₂ (PGE₂) and the expression of cyclooxygenase-2 (COX-2) were examined using RAW 264.7 macrophages activated with lipopolysaccharide (LPS). Both prescriptions dose-dependently reduced the release of PGE2 and expression of COX-2 caused by stimulation of LPS without cytotoxic effect. Kagam-bojungikgitang's inhibitory effects were better than Bojungikgitang in PGE2 production and COX-2 expression. Moreover, Kagam-bojungikgitang also attenuated markedly the production of tumor necrosis factor (TNF)-α, and IL-6 than Bojungikgitang in LPS-stimulated RAW 264.7 macrophages. These results suggest that Kagam-bojungikgitang decreases PGE2 and pro-inflammatory cytokine production in macrophages and these properties may contribute to the anti-inflammatory activity of Kagam-bojungikgitang.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.4
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• pp.469-474
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• 2012

Fagopyrum esculentum(FE) is an important food crop and medicinal plant that is used to improve diabetes, obesity, hypertension, hypercholesterolemia and constipation in Korea, but the underlying mechanisms involved in its anti-allergic activity are not fully understood. We investigated the effects on the release of inflammatory mediator and proximal signal events in $Fc{\varepsilon}RI$-mediated RBL-2H3 cell activation. FE reduced antigen (DNP-HSA)-induced release of histamine, prostaglandin D2 (PGD2) and cysteinyl Leukotriene (cysLT) in IgE-sensitized RBL-2H3 cells. In addition, it inhibited antigen-induced HDC2 and COX-2 and 5-LO mRNA expression in IgE-sensitized RBL-2H3 cells. FE also suppressed antigen-induced $Fc{\varepsilon}RI{\beta}$ and $Fc{\varepsilon}RI{\gamma}$ subunit mRNA expression in these cells. To identify the mechanisms underpinning the inhibition of release of inflammatory mediators such as histamine and PGD2 and cysLT by FE, we examined the proximal signal events of intracellular FceRI signaling molecules. FE suppressed antigen-induced phosphorylation of Lyn, Syk, LAT, $PLC{\gamma}1$, PI3K, Akt and cPLA2. Collectively, the anti-allergic effects of FE in vitro suggest its possible therapeutic application to inflammatory allergic diseases, in which its inhibition of inflammatory mediator and FceRI-dependent signaling events in mast cells may be hugely beneficial.

• Herbal Formula Science
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• v.11 no.1
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• pp.115-128
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• 2003

Bojungikgitang is the water extracts prepared from Ginseng Radix, Astragali Radix, Angelicae gigantis Radix, Astractylodis Rhizoma alba, Aurantii nobilis Pericarpium, Glycyrrhizae Radix, Bupleuri Radix, Cimicifugae Rhizoma, which has been used for the treatment of indigestion, and immunological disease in oriental countries. In this study, the effects of Bojungikgitang on the productions of nitiric oxide (NO) and prostaglandin $E_2\;(PGE_2)$, and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were examined using RAW 264.7 macrophages activated with $interferon-{\gamma}\;(IFN-{\gamma})$ plus lipopolysaccharide (LPS). Bojungikgitang (10-400 ${\mu}$g/ml) per se had no cytotoxic effect in unstimulated macrophages, but this compound dose-dependently reduced the release of NO and $PGE_2$ caused by stimulation of $LPS/IFN-{\gamma}$. The levels of iNOS and COX-2 protein were markedly suppressed by the treatment with Bojungikgitang in a concentration dependent manner. Moreover, Bojungikgitang also attenuated the production of tumor necrosis factor (TNF)-${\alpha}$, interleukin (1L)-1${\beta}$ and IL-6 in LPS-stimulated RAW 264.7 macrophages. These results suggest that Bojungikgitang decreases the NO and $PGE_2$ production in macrophages by inhibiting iNOS and COX-2 expression and these properties may contribute to the anti-inflammatory activity of Bojungikgitang.

• Journal of Korea Multimedia Society
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• v.7 no.7
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• pp.967-975
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• 2004

HTML is unstructured document because of using restricted tag. HTML is difficult to extract data from HTML document. But XML is able to use user definition tag, that is easy to store information. Also XML is easy to extract data from XML document. This is the reason why XML is a standard for data exchange format on the Internet, so XML is fitted to exchange data between heterogeneous DBMSs(DataBase Management System). In this paper, we designed and implemented of XML web agent for data replication between heterogeneous DBMSs. A XML web agent system controls data of DBMS, and generates a XML document from data of DBMS. Also XML web agent is data exchange or replication between heterogeneous DBMS by the medium of XML.

• KOREAN ASSOCIATION OF OCCUPATIONAL HEALTH NURSES
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• v.8 no.2 s.28
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• pp.10-18
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• 2001

우리나라 대기오염의 수준은 지난 90년대 초반 이후 아황산가스와 총부유분진의 농도가 감소하고, 대신 오존과 이산화질소의 농도가 증가하면서 점차 다른 선진국에서 경험하는 대기오염현황을 보이고 있다. 한편 PM10과 PM2.5와 같은 미세분진의 경우 그 측정기간이 짧고 자료가 제한적이지만, 일부 지역에서 증가추세를 보이고 있으며, 그 수준을 비교하였을 때 현재 선진국에서 책정한 미세분진의 규제농도를 훨씬 상회하는 것으로 판단된다. 대기오염으로 인한 건강영향으로는 급성으로 고농도에 수 시간에서 수 일 동안 노출되는 경우 폐기능의 저하, 심박동의 변화, 그리고 신체내 염증물질의 증가 등 인체 기능의 변화가 보고되고 있으며, 기존에 폐장질환이나 심혈관질환을 앓고 있는 사람들의 경우 증세의 악화와 의료이용의 증가 등을 경험하거나 더 나아가 사망에 이르러 수명이 단축되는 것이 보고되고 있다. 급성노출의 경우 미세분진 PM10 10 $\mu$m/m3 당 전체 사망률이 0.5-1$\%$ 가량 증가하는 것으로 보고되며, 만성노출을 조사한 코호트 연구에 근거하는 경우 대기오염에 노출되는 전체 인구에 있어 PM2.5 1 $\mu$m/m3 당 1개월의 수명이 단축되는 것으로 추정되고 있다. 아직 대기오염으로 인한 건강영향의 기전이 전부 밝혀진 것은 아니지만, 일부 연구에서 대기오염물질 중에서 전이금속의 역할이 보고되고 있으며, 대기오염에 노출되면서 기관지, 폐포 및 혈액 등에서 염증매개물질의 분비 및 확산 그리고 심장을 비롯한 각 장기 기능의 변화가 보고되고 있다. 한편 이러한 변화들이 증세와 건강상의 비가역적 변화를 야기하는데 있어 대기오염 수준의 역치는 없는 것으로 판단되고 있다. 이러한 대기오염의 영향에 대한 개인수준의 해결책으로서는 자동차 사용의 절제 및 개인적인 쓰레기 소각의 자제 등 오염원 발생의 감소와 함께 대기오염 수준에 따른 증세 및 투약의 적절한 조절과 신체 활동의 조절을 통하여 오염원을 회피하는 것이 강조되어야 하며, 또한 흡연 특히 실내흡연의 금지와 실내 주방기구 및 난방기구의 관리 등이 구체적으로 제시될 수 있다. 마지막으로 대기오염물질들이 신체에 들어와 산화제로 작용하는 만큼, 식품을 통한 항산화제의 섭취가 일반적인 건강관리 수준에서라도 반드시 강조되어야 할 것이다.