• Tuberculosis and Respiratory Diseases
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• v.59 no.2
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• pp.142-150
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• 2005

Background : Continuous growth stimulation by various factors, as well as chronic oxidative stress, may co-exist in many solid tumors, such as lung cancer. A new family of antioxidant proteins, the peroxiredoxins (Prxs), have been implicated in the regulation of many cellular processes, including cell proliferation, differentiation and apoptosis. However, a real pathophysiological significance of Prx proteins, especially in lung disease, has not been sufficiently defined. Therefore, this study was conducted to investigate the distribution and expression of various Prx isoforms in lung cancer and other pulmonary conditions. Method : Patients diagnosed with lung cancer, and who underwent surgery at the Ajou Medical Center, were enrolled. The expressions of Prxs, Thioredoxin (Trx) and Thioredoxin reductase (TR) were analyzed using proteomic techniques and the subcellular localization of Prx proteins was studied using immunohistochemistry on normal mouse lung tissue. Result : Immunohistochemical staining has shown the isoforms of Prx I, II, III and V are predominantly expressed in bronchial and alveolar lining epithelia, as well as in the alveolar macrophages of the normal mouse lung. The isoforms of Prx I and III, and thioredoxin were also found to be over-expressed in the lung cancer tissues compared to their paired normal lung controls. There was also an increased amount of the oxidized form of Prx I, as well as a putative truncated form of Prx III, in the lung cancer samples when analyzed using 2-dimensional electrophoresis. In addition, a 43 kDa intermediate molecular weight protein band, and other high molecular weight bands of over 20 kDa, recognized by the anti-Prx I antibody, were present in the tissue extracts of lung cancer patients on 1-Dimensional electrophoresis, which require further investigation. Conclusion : The over-expressions of Prx I and III, and Trx in human lung cancer tissue, as well as their possible chaperoning function, may represent an attempt by tumor cells to adjust to their microenvironment in a manner advantageous to their survival and proliferation, while maintaining their malignant potential.

• Journal of Periodontal and Implant Science
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• v.35 no.3
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• pp.649-659
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• 2005

The purpose of this study was to quantify and compare the level of MMP-1 in the healthy or inflamed gingival tissue of patients with or without type 2 diabetic mellitus. We investigated whether mean amount of MMP-1 was changed by chronic periodontitis and type 2 DM. Gingival tissue samples were obtained during periodontal surgery or tooth extraction. According to the patient's systemic condition & clinical criteria of gingiva, each gingival sample was divided into the three group. Group 1(n=8) was clinically healthy gingiva without bleeding and no evidence of bone resorption or periodontal pockets, obtained from systemically healthy 8 patients. Group 2(n=8) was inflamed gingiva from patients with chronic periodontitis. Group 3(n=8) was inflamed gingiva from patients with chronic periodontitis and type 2 diabetes. Tissue samples were prepared and analyzed by Western blotting. The quantitative analysis of MMP-1 was performed using a densitometer and statistically analyzed by ANOVA. MMP-1 was expressed in all samples and an increased MMP-1 level was observed in group 2 compared to group 1 and decreased MMP-1 level was found group 3 compared to group 2, but the differences among 3 groups were not statistically significant. In conclusion, this study demonstrated that MMP-1 levels of inflamed gingiva of systemically healthy patient(group 2) were higher than normal gingiva of systemically health patients and although the severity of gingival inflammation in group 2 and 3 were similar, MMP-1 expression was decreased in diabetic patients than systemically healthy periodontal patients.

• Applied Biological Chemistry
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• v.33 no.4
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• pp.277-281
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• 1990

Injeulmi(Korean glutinous rice cake) was prepared without, 5, 10 and 15% of macerated tea leaves for utilizing unplucked low-graded tea leaves. The effect of firming rate by addition of tea leaf was determined using the Avrami's equation in terms of the texture parameters. Hardness of 5, 10 and 15% addition as compared with no addition was decreased gradually. Overall texture was softened in proportion to Increasing the content of added tea leaf and the addition of 5% and 10% were evaluated as the highest score as an acceptable sensory quality. Avrami exponents and time constant obtained from the Avrami's equation applicable for changes in hardness of without and 10% addition during 7days of storage at $20^{\circ}C$, $90{\sim}95%$ RH indicated 1.062, 15.3 and 0.989, 41.6, respectively, as showing the effect of delay on firming rate.

• Journal of Veterinary Clinics
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• v.31 no.2
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• pp.159-162
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• 2014

A 4-month-old female thoroughbred foal was presented with large mass on mandibular gingiva. The enlarged mass was firm and yellowish pink in color, and occupied the whole mandibular arcade. The filly could not close her mouth with her lips. Radiographs showed radioopaque mass under the mandible. The mass was surgically excised from mandible. Histopathologically, gingival mass was characterized by hyperplastic gingival epithelium, well vascularized collagenous stroma and large area of bony tissues. Based on the gross and histopathologic findings, this case was diagnosed as ossifying epulis in the mandibular gingiva. This is the first report of ossifying epulis in a thoroughbred horse in Korea.

• Information Systems Review
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• v.9 no.1
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• pp.311-341
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• 2007

This paper presents a case study on BSC(Balanced Scorecard) system development of Korea Post as a Korean public firm. BSC models of public or private sector are generally developed in different types due to their different strategic goals. Korea Post as a government firm has dual characteristics of BSC similar to both public and private sector. This firm has the organizational type of public firms, not private firms. To date many government subsidiary organizations have already introduced BSC or are trying to introduce BSC, but have difficulty in developing BSC successfully because of insufficient understanding of BSC. Based on a case study of Korea Post, this study analyzed key success and failure factors and suggested prospects on BSC system development of public firms.

• Convergence Security Journal
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• v.13 no.2
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• pp.85-93
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• 2013

Today, the structure of terrorist organizations in the form of a variety of network complexity are evolving. However, terrorist organization not combining randomly generated network but preferential attachment a network. So, it's research should be preceded a better understanding about the characteristics and type of terror network for a effective counter-terrorism policy of law enforcement. In addition, the appropriate response strategy have to technique establish in an era of smart media. In particular, homegrown terrorist attacks on unspecified people without boundaries of countries and regions unlike the traditional terrorism. Also, homegrown terrorism are violence and criminal activity by new various of religion, politics, philosophy. Besides the extreme members of homegrown terror networks went grow up through the evolutionary process in the age of smart media. Law enforcement agencies must identify the terrorist network at the national level. Therefore, terror networks evolving in the online space, forming a radical homegrown terror organizations have access to the network. Intelligence community track terrorist networks and to block the negative aspects of the smart media outlets should be considered.

• Proceedings of the Ginseng society Conference
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• 1984.09a
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• pp.145-152
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• 1984

Toxohormone-L (THL) elicited fatty acid release from rat epididymal adipose tissue, which is present in cancerous ascites fluids. In this study, the effect of ginseng powder on lipolysis induced by Toxohormane-L, and ACTH was studied. Korean ginseng selectively inhibited Toxohormone-L induced lipolysis, but did not inhibit ACTH-induced lipolysis.

• Journal of Plant Biology
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• v.38 no.1
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• pp.115-119
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• 1995

In order to clarify the relationship between the activity and age of vacular cambium in the rhizome of Botrychium ternatum, the cambia of the 6th and 10th internodes from its shoot apex were compared ultrastructurally and histochemically. The cambium in the 6th internode had two to four radially arranged cells in each row, and the cells are radially flattened and had thiner tangential walls than radial. The cambial cells were ultrastructurally characterlized by the presence of a large vacuole, few storage materials such as starch grains and lipid droplets, and various cell organelles such as mitochondria, endoplasmic reticulums and dictyosomes in cytoplasm. On the other hand, the cells of cambium in the 10th internode showed irregular arangement and somewhat enlargement in radial plane. The cells were filled with numerous storage materials and small vacuoles and had few cell organelles except for mitochondria. In addition, the activity of acid phosphatase appeared in the cambium of the 6th internode but of the 10th. From the above results, it is clear that the vascular cambium of the 6th internode was active and that of the 10th was dormant. Thus we reached a conclusion that the rhizome of '||'&'||'trychium ternatum has determinate cambium.

• Journal of Digital Convergence
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• v.10 no.11
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• pp.225-234
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• 2012

OSS(Open source software) pursues the freedom to have access to open source and offers several advantages, over the proprietary software, to enterprises. Based upon Rogers(1995)' innovation-diffusion process, we assume that attributes of innovations includes five characteristics of innovations: relative advantage, compatibility, complexity, trialability, and observability, and that firms' perceptions of these characteristics predict the rate of adoption of OSS. To test this hypothesis, we presents a survey result from 201 companies and institutions concerning the use of OSS. Statistical analysis shows that adoption is highly correlated with each of those characteristics of innovations, but the regression analysis indicates that only compatibility and observability have effects on the adoption of OSS. This implies that intrinsic value of OSS is important, but unless the appropriate service package for improving IT environment is provided, it is not easy to change the perspective of corporate customers more favorable toward OSS use. As a conclusion, the academic and practical implications are also discussed.

• Journal of Veterinary Clinics
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• v.29 no.5
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• pp.427-430
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• 2012

An infertile, three-year-old primiparous cow was diagnosed preliminarily with pyometra by rectal palpation at 180 days postpartum. Ultrasonography showed that the cranial portion of the right uterine horn was distended with fluid, while the base portion of the horn was missing. A dense band of tissue connected the cranial portion of the uterine horn to the uterine body. However, the left uterine horn was normal. Gross postmortem analysis of the reproductive organs confirmed the ultrasonographic observations. Histopathological observations also showed that dark red-brown mucus filled the thin-walled right uterine horn, where neither caruncles nor uterine glands were observed. Finally, this primiparous Holstein cow was diagnosed with segmental aplasia of the right uterine horn.