• Title/Summary/Keyword: 동형

Search Result 617, Processing Time 0.028 seconds

The Correctness Comparison of MCIH Model and WMLF/GI Model for the Individual Haplotyping Reconstruction (일배체형 재조합을 위한 MCIH 모델과 WMLF/GI 모델의 정확도 비교)

  • Jeong, In-Seon;Kang, Seung-Ho;Lim, Hyeong-Seok
    • The KIPS Transactions:PartB
    • /
    • v.16B no.2
    • /
    • pp.157-161
    • /
    • 2009
  • Minimum Letter Flips(MLF) and Weighted Minimum Letter Flips(WMLF) can perform the haplotype reconstruction more accurately from SNP fragments when they have many errors and gaps by introducing the related genotype information. And it is known that WMLF is more accurate in haplotype reconstruction than those based on the MLF. In the paper, we analyze two models under the conditions that the different rates of homozygous site in the genotype information and the different confidence levels according to the sequencing quality. We compare the performance of the two models using neural network and genetic algorithm. If the rate of homozygous site is high and sequencing quality is good, the results of experiments indicate that WMLF/GI has higher accuracy of haplotype reconstruction than that of the MCIH especially when the error rate and gap rate of SNP fragments are high.

Photo-responsive Smart Polymer Materials (광 응답형 스마트 고분자 소재)

  • Yu, Jong-Su;Lee, Seong-Yun;Na, Hee-Yeong;Ahn, Tae-Jung;Kim, Hyun-Kyoung
    • Elastomers and Composites
    • /
    • v.47 no.4
    • /
    • pp.282-291
    • /
    • 2012
  • Control of shape/volume, mechanical, optical, electrical, and chemical switching of materials by external stimuli such as light, temperature, pH, electric field, and pressure has attracted great attention. Among these materials, photo-responsive materials containing photochromic compounds such as azobenzene, spiropyran, and cinnamic acid groups have been the subject of intense interest in recent years. In this review, we describe the recent progress in the area of azobenzene containing polymer materials that can convert light energy into mechanical energy directly. Especially we focus our attention on light-driven actuators such as artificial muscle, motor, and valve. We summarize the photomechanical effects in liquid crystal elastomer, amorphous polymer, monolayer, and supramolecules containing azobenzene, respectively.

Analysis of abduction and thinking strategies by type of mathematical problem posing (수학 문제 만들기 유형에 따른 가추 유형과 가추에 동원된 사고 전략 분석)

  • Lee, Myoung Hwa;Kim, Sun Hee
    • The Mathematical Education
    • /
    • v.59 no.1
    • /
    • pp.81-99
    • /
    • 2020
  • This study examined the types of abduction and the thinking strategies by the mathematics problems posed by students. Four students who were 2nd graders in middle school participated in problem posing on four tasks that were given, and the problems that they posed were classified into equivalence problem, isomorphic problem, and similar problem. The type of abduction appeared were different depending on the type of problems that students posed. In case of equivalence problem, the given condition of the problems was recognized as object for posing problems and it was the manipulative abduction. In isomorphic problem and similar problem, manipulative abduction, theoretical abduction, and creative abduction were all manifested, and creative abduction was manifested more in similar problem than in isomorphic problem. Thinking strategies employed at abduction were examined in order to find out what rules were presumed by students across problem posing activity. Seven types of thinking strategies were identified as having been used on rule inference by manipulative selective abduction. Three types of knowledge were used on rule inference by theoretical selective abduction. Three types of thinking strategies were used on rule inference by creative abduction.

A study on the improvement of a suspension system adopting a semiactive on-off damper (반능동 단속형 감쇠기를 이용한 현가장치 개선에 관한 연구)

  • 최성배;박윤식
    • Transactions of the Korean Society of Mechanical Engineers
    • /
    • v.12 no.5
    • /
    • pp.959-967
    • /
    • 1988
  • In this paper, 2-DOF vehicle suspension system with a semiactive on-off damper was studied for improving the ride comfort. It is known that a nonlinear hydraulic damper, which generates force proportional to the square of the relative velocity, can describe the actual fluid resisting type damper more properly than the traditional viscous damping model. On the other hand, hydraulic damper adoption in analysis makes the system nonlinear and causes difficulties to get the system response. In this work, time domain direct integration method was used to calculate system displacement and acceleration. first of all, the response of the suspension system experiencing a given road profile was optimized by Lagrangian multiplier method within the range of given damping coefficients. The appropriate on-loaf damping values were obtained by averaging the already calculated optimum damping coefficients from Lagrangian techniques. The criterion to control the on-off mechanism was determined by examining the suspension efficiency. It was found that the best out of practically applicable criteria is following the sign (positive and negative) of the multiplication of relative displacement and velocity. Judging from the theoretical calculations, it was proved that the semiactive on-off damper can increase suspension efficiency as much as 8-11% in object function.

Expression of ATE2 Transcription Factor and the Interaction with AP-1 Factors : BATF, c-Fos, c-Jun (ATF2 전사인자의 발현과 AP-1 전사인자인 BATF, c-Fos, c-Jun과의 이량체 형성)

  • Jang Hye-Young;Kim Jae-Ho
    • Journal of Life Science
    • /
    • v.15 no.6 s.73
    • /
    • pp.928-934
    • /
    • 2005
  • ATF2 is a cellular transcription factor which belongs to the CREB/ATF class and it is leucine zipper protein which generally binds to DNA as dimers. This paper presents the procedure for subcloning the ATF2 gene and the results of experiment used the expressed ATF2. The pET expression vector was used since it produced 6xHis fusion protein for easy purification using affinity column. The Nickel chelating chromatography was used for Purifying the expressed ATE2 from E- codi BL2l. Subsequen시y In vitro binding pull-down assay showed the binding specificity of ATF2 with AP-1 family factors such as BATF, c-Fos, c-Jun and ATF2 itselgf. ATF2 forms homodimer as well as strong heterodimer with BATF. It also forms stable dimer with c-Jun but barely binds with c-Fos.

Shared Governance for the Arts and Culture - US Public Arts Agencies and Cultural Foundations (문화예술활동 지원을 위한 지역과 중앙의 공유 거버넌스 - 미국의 지역예술위원회와 문화재단의 활동을 중심으로)

  • Chang, WoongJo;Lee, Dahyun
    • Review of Culture and Economy
    • /
    • v.21 no.1
    • /
    • pp.63-83
    • /
    • 2018
  • In the US, there are no governing bodies within the federal executive departments dedicated to the arts and cultural affairs. Direct government subsidies for the arts are relatively small compared to other countries with a comparable economy and standard of living. Nevertheless, the US produces artworks, artists, and arts groups, leading the world's arts and culture. Incorporating the concepts of network governance and shared governance, this paper examines the dynamic roles and interrelationships among various for-profit/nonprofit arts organizations, foundations, councils, service organizations, arts advocacy groups, and professional/amateur associations from the federal to local levels that compose the ecology of American arts and culture. Through our evaluation, we conclude that the local/state/federal arts agencies and arts organizations at various levels influence each other via the principle of subsidiarity and isomorphism, creating a unique cultural policy and arts-supporting system that correspond to the political and social structure and environment of the United States.

An Efficient Dynamic Optimization Method for Large Structures with Frequency Constraints (진동수 구속조건을 갖는 대형구조계의 효율적 동특성 최적화방법)

  • B.H. Kim;T.Y. Chung;K.C. Kim
    • Journal of the Society of Naval Architects of Korea
    • /
    • v.31 no.2
    • /
    • pp.91-98
    • /
    • 1994
  • An efficient optimization procedure combining the frequency approximation technique and the component-mode synthesis method is proposed for the structural dynamic optimization of the large structures subject to prescribed natural frequency constraints. Frequency constraints are approximated by using the first-order sensitivities with respect to both design parameters and their reciprocals. The component-mode synthesis method proposed by the authors in Ref.[8] is used for the repetitive detail finite-element analysis and sensitivity analysis. The validity of the proposed optimization procedure is confirmed through the numerical implementation of some examples. The presented approximation technique requires much smaller number of repetitive analysis than that using the sensitivities with respect to design parameters only, and further improvement in the numerical efficiency is achieved by the adoption of the introduced component-mode synthesis.

  • PDF

The 21st Korean National Assembly Election and Changes in the Party System: Intended Design and Unintended Consequences (제21대 국회의원 선거와 정당체제의 변화: 의도된 설계와 의도하지 않은 결과)

  • Yoon, Jisung
    • Korean Journal of Legislative Studies
    • /
    • v.26 no.2
    • /
    • pp.5-33
    • /
    • 2020
  • Ahead of the 21st Korean National Assembly Election, the congressional election law was revised, and the semi-mixed member proportional system was introduced. The purpose of the revision of the election law was to increase the proportionality and representativeness of the election system through the institutional reform in the direction of promoting a multi-party system. This study shows that the effect of the introduction of the semi-mixed proportional system was compared with the election results when the previous proportional representative system was maintained. There was no significant difference from the results. This study reveals that contrary to the intention of institutional design to revitalize the multi-party system, the two large political parties took the most seats after democratization in 1987, resulting in an unintended consequences. In addition, with regard to the recent argument for party realignment, the Busan, Ulsan, and Gyeongnam regions have been dealigned in the Yeongnam regional cleavage, and are undergoing a process of party realignment. It has not yet entered the stage of realignment, but remains in the stage of fluid dealignment.

A study on the path following of an unmanned surface vessel (무인선의 경로추종에 관한 연구)

  • Hansol Park;Namsun Son;Chunseon Pyo;Jae yong Lee
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
    • /
    • 2022.11a
    • /
    • pp.187-187
    • /
    • 2022
  • 최근 선박의 자율운항기술이 활발하게 연구되어 오면서, 경로추종 제어 및 충돌회피 등의 자율운항 기술 연구가 많이 진행되고 있으며 그에 따른 시뮬레이션과 실해역 시험 등도 활발하게 수행되고 있다. 이러한 자율운항기술 중 본 연구에서는 AUV(Autonomous Underwater Vehicle) 진회수 시 모함에 활용되며 쌍동선형을 갖는 쌍동형 무인수상선을 대상으로 경로추종 제어에 대한 실해역 시험을 수행한 내용을 소개한다. 대상선인 쌍동형 무인수상선은 배수량이 약 10ton, 최대속도 10knots를 기준으로 설계된 선형이며 Sail drive 타입의 쌍축 추진기를 탑재하고 있으며 Fig. 1에 나타내었다. 실해역 시험은 경기도 화성시에 위치한 제부마리나 전면 해역에서 여러 속도에 대해 Fig. 2의 경로(빨간색)를 활용하여 수행되었다. 해당 경로는 변침각이 45도까지 이루어져 있다. 경로추종 제어 알고리즘은 목표경유점을 향하기 위해 선수각을 제어하는 부분과 목표속도로 추진하기 위해 속도를 제어하는 부분으로 나뉘어져 있다. 선수각 제어 시 경로와 무인선과의 위치 오차를 줄이는 방향으로 선수각이 향할 수 있도록 알고리즘이 설계되었다. 속도 제어의 경우 RPM 별로 실제 속도를 계측하여 데이터화 한 후, 실제 속도가 명령 속도와 다를 경우 RPM을 가감하여 명령 속도로 추진하기 위해 제어할 수 있도록 하였다. Fig. 2에서 파란색 선은 설계한 알고리즘을 활용하여 경로추종 제어를 한 결과의 궤적을 보여준다.

  • PDF

Privacy model for DTC genetic testing using fully homomorphic encryption (동형암호를 활용한 DTC유전자검사 프라이버시모델)

  • Hye-hyeon Jin;Chae-ry Kang;Seung-hyeon Lee;Gee-hee Yun;Kyoung-jin Kim
    • Convergence Security Journal
    • /
    • v.24 no.2
    • /
    • pp.133-140
    • /
    • 2024
  • The spread of Direct-to-Consumer (DTC) genetic testing, where users request tests directly, has been increasing. With growing demand, certification systems have been implemented to grant testing qualifications to non-medical institutions, and the scope of tests has been expanded. However, unlike cases in less regulated foreign countries, disease-related tests are still excluded from the domestic regulations. The existing de-identification method does not adequately ensure the uniqueness and familial sharing of genomic information, limiting its practical utility. Therefore, this study proposes the application of fully homomorphic encryption in the analysis process to guarantee the usefulness of genomic information while minimizing the risk of leakage. Additionally, to safeguard the individual's right to self-determination, a privacy preservation model based on Opt-out is suggested. This aims to balance genomic information protection with maintainability of usability, ensuring the availability of information in line with the user's preferences.