• The Journal of Korean Association of Computer Education
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• v.14 no.2
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• pp.83-94
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• 2011

In the biomedical domain, the longest matching method is frequently used for recognizing named entity written in the literature. This method uses a dictionary as a resource for named entity recognition. If there exist appropriated dictionary about target domain, the longest matching method has the advantage of being able to recognize the entities of target domain quickly and exactly. However, the longest matching method is difficult to recognize the enumerated named entities, because these entities are frequently expressed as being omitted some words. In order to resolve this problem, we propose the partial matching method using a dictionary. The proposed method makes several candidate entities on the assumption that the ellipses may be included. After that, the method selects the most valid one among candidate entities through the optimization algorithm. We tested the longest and partial matching method about HLA entities: HLA gene, antigen, and allele entities, which are frequently enumerated among biomedical entities. As preparing for named entity recognition, we built two new resource, extended dictionary and tag-based dictionary about HLA entities. And later, we performed the longest and partial matching method using each dictionary. According to our experiment result, the longest matching method was effective in recognizing HLA antigen entities, in which the ellipses are rare, and the partial matching method was effective in recognizing HLA gene and allele entities, in which the ellipses are frequent. Especially, the partial matching method had a high F-score 95.59% about HLA alleles.

• Journal of the Korean Institute of Landscape Architecture
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• v.36 no.6
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• pp.102-114
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• 2009

Urban discourse can be used to create a better living environment through open thinking, understanding and discussion. It raises both physical and social issues surrounding the urban environment. It can encourage the participation of citizen groups and lead the way to develop a community-oriented urban environment through inter-discourse agreement. The urban space of Cheonggye Stream has produced a wide range of urban discourse from 2003 to the present. Discourse regarding the Cheonggye Stream restoration project has been approached by fields including landscape architecture, ecology, urbanism, architecture, politics, and economics, among others. This discourse has reduced a variety of issues and ranges of debate. This study has classified these discussions into related fields and ideological attitudes, analysed their content, and interpreted their meaning. In order to examine the mutual relationships existing among these discourses by different ideological groups, an analytical framework was established byputting classified versions of discourses into a coordinate diagram. The overall topography showing the present status of Korea public awareness regarding the urban environment could therefore be determined. As a result, it was found that the disciplines of landscape architecture took a middle ground between groups with practical and radical ideologies regarding the Cheonggye Stream project and was a mediator for both poles to find a point of contact. However, participatory discourse requires the disciplines of landscape architecture to participate more actively in the discourses on urban environment and take a more active stand corresponding to the zeitgeist and people's sense of public justice.

• Korean Journal of Construction Engineering and Management
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• v.8 no.5
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• pp.161-172
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• 2007

By prosperous condition of construction economy in the early 90s in Korea, the government needed a lot of the qualified professional engineers (PE) to manage the construction site. In order to meet the high demand of P.E., Government has established the admitted engineer systems(AES) in 1995 that give the authority of principal engineers to the admitted engineers who do not take the written examination but have equivalent working experience. Since 2000, professional $engineer^{\circ}{\phi}s$ shortage has been resolved. however, the opposite situation, which is serious over-supply of construction engineers has occurred. Thus, Government announced that would abolish the admitted engineer systems as recognized the existent admitted engineers(about 1,000,000 persons) from 2007. However, Professional Engineers Institution has strongly insisted that Government should not recognize existent admitted engineers. From this point of view, it is critical to make the supply-demand forecast systems as a derivative approach of System Dynamics also, that is useful in comparing the argument between Government and Professional Engineers Institution. This paper describes about principal $engineer^{\circ}{\phi}s$ supply change by admitted engineer system abrogation and suggests the idea to regulate the supply and demand with the improvement of the regal system.

• Journal of Life Science
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• v.27 no.4
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• pp.464-470
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• 2017

Three Korean native cattle (KNC) and seven exotic breeds (Chikso, Hanwoo, Jeju black, Holstein, Japanese black, Charolais, Angus, Hereford, Simmental, and Cross breed) were characterized by using five microsatellite (MS) markers (INRA30, TGLA325, UMN0803, UMN0905, and UMN0929) from the sex chromosome. Genetic diversity was evaluated across the 10 breeds by using the number of alleles per locus, allele frequency, heterozygosity, and polymorphism information content (PIC) to search for locus and/or breed specific alleles, allowing a rapid and cost-effective identification of cattle samples, avoiding mislabeling of commercial beef. It was divided into two main groups from STRUCTURE analysis, one corresponding to KNC and the other to exotic cattle breeds. These results also showed specific genetic differences between KNC and exotic breeds. Nei's standard genetic distance was calculated and used in the construction of a neighbor-joining tree. Results evidenced a correspondence between genetic distance, breeds' history, and their geographic origin, and a clear separation between KNC and exotic breeds. Overall, this study evidenced that DNA markers can discriminate between domestic and imported beef, contributing to the knowledge on cattle breeds' genetic diversity and relationships by using MS markers of the sex chromosome. These markers would be useful for inhibitory effect about false sales and for building an effective tracking system.

• Korean Journal of Ichthyology
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• v.20 no.4
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• pp.248-254
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• 2008

Olive flounder (Paralichthys olivaceus) is one of the most popular farmed fish in Korea. Genetic variability of the fish was investigated by means of microsatellite DNA markers. All of the 8 microsatellite loci were analyzed in this study. For the confirmation of genetic variation during a shift in generation, microsatellite variability was compared within the same hatchery strains but produced in different spawning years. When genetic variability of farmed flounders produced in 2006 and 2007 was compared with that of 2003, a marked reduction of genetic variability was observed in the 2006 and 2007 populations. Mean number of alleles per locus and expected mean heterozygosity decreased from 9.75 and 0.796 (in 2003 population) to 7.78 and 0.785 (in 2006 population), respectively. Moreover, we have observed the distortion of allele frequency. These results show that reduced genetic variability of farmed olive flounder in processed generation has lower numbers of alleles and genetic variability than these of wild fish. Our results suggest that to have a sustainable aquaculture of this species, there is need for scientific broodstock management based on genetic variation and more intensive breeding practices to improve genetic diversity and to avoid detrimental inbreeding effects.

• Journal of Periodontal and Implant Science
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• v.36 no.1
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• pp.113-123
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• 2006

연구배경 IgG에 대한 $Fc{\gamma}$ 수용기는 치주병인균에 대한 숙주 반응에 있어서 중요한 역할을 하는데, 이 중 $Fc{\gamma}RIIIa$는 NK 세포, 대식세포, 단핵구, ${\gamma}{\delta}T$세포에서 발현되며, EC2 도메인에서 158 아미노산 부위의 valine (V)-phenylalanine (F)의 유전자다형성을 보인다. $Fc{\gamma}RIIIb$는 특이적으로 중성구에 발현되는데, extracellular (ECl) Ig-like 도메인 내 4개의 아미노산 치환(substitutions)에 의한 NA1-NA2 유전자다형성을 보인다. 이 연구의 목적은 한국인에서 급진성 치주염 환자와 $Fc{\gamma}III$ 수용기의 유전자다형성과의 관련성을 알아보는 것이다. 연구방법 및 재료 치주적으로 건강한 90명 (대조군, 남자 64명, 여자 26명)과 서울대학교 치과병원 지주과에 내원하여 급진성 치주염으로 진단된 환자 43명 (aggressive periodontitis patients: AgP, 남자 30명, 여자 13명)을 대상으로 하였다. 모든 실험 대상자는 임상 실험에 대해 동의 하였고, 초진 시 전자 탐침(Florida Probe(R) Co. Gainesville, FL)을 이용하여 탐침 시 치주낭 깊이 (PPD), 임상부착수준 (CAL), 치태지수(PI), 탐침 후 출혈지수 (BOP)를 측정하였다. 또한 이들의 정맥혈에서 추출한 DNA를 PCR법, 전기영동법 등을 이용하여 $Fc{\gamma}RIIIa$, $Fc{\gamma}RIIIb$의 대립 유전자의 존재여부를 확인하였다. 이를 바탕으로 $Fc{\gamma}RIII$ 복합 유전형을 확인하여 각 군 간을 비교하였다. 연구 결과 1. $Fc{\gamma}RIIIa$에 대한 유전자다형성 연구 결과 대조군과 급진성 치주염 환자 군(AgP)사이에서는 대립 유전자 분포가 서로 유의성 있는 차이를 나타내었고 (P<0.05), $Fc{\gamma}RIIIb$에서는 유의성 있는 차이를 발견할 수 없었다. (P>0.05) 2. $Fc{\gamma}RIIIa$ 158F 대립형질이 급진성 치주염 환자에서 유의성 있게 많이 발견되어졌다. (P<0.05) 결론 이 연구를 통하여 $Fc{\gamma}RIIIa$ 유전자의 분석이 한국인의 급진성 치주염에 대한 감수성의 위험요소의 표지자로 활용할 수 있을 것으로 사료되며, 향 후 더 많은 환자를 대상으로 히는 추가 연구가 필요하다고 생각된다.

• Sleep Medicine and Psychophysiology
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• v.14 no.1
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• pp.26-32
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• 2007

Objectives: Angiotensin-converting enzyme (ACE) gene polymorphism has been reported to be associated with depression and therapeutic outcome in depression. The purpose of this study was to determine whether ACE gene polymorphism is associated with seasonal variation in mood and behavior in a young Korean college student sample. Methods: 297 young Korean medical students were recruited in this study. All subjects were free of major medical and psychiatric problems. They were genotyped for the ACE gene polymorphism and evaluated the seasonal variation in mood and behavior by the Seasonality Pattern Assessment Questionnaire (SPAQ). Results: Global Seasonality Score (GSS) of SPAQ between three genotypes were not different. However, comparison of the group that showed seasonality of mood and behavior during winter with the group that did not showed seasonality indicated significant difference in genotype distribution ($x^2=6.79$, p=0.034). The D allele non-carrier (ll genotype) frequency was significantly higher in winter seasonality group than non-seasonality group ($x^2=6.59$, p=0.010；odds ratio [OR]=2.27, 95% confidence interval [CI] 1.20-4.28). Conclusion: These results suggest that the ACE gene polymorphism is related to winter-type seasonality in a Korean population.

• Journal of Life Science
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• v.20 no.7
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• pp.1086-1092
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• 2010

To estimate the genetic characteristics and cumulative power of discrimination (CPD) within Korean native commercial chicken, we used a total of 395 genomic DNAs from six breeds population (Korean Native Red chicken: R, Korean Native Yellow chicken: Y, Korean native Commercial Chicken: C, Ogal chicken: S, Hy-Line Brown: H, White Leghorn: W). Genetic diversity indices including mean allele number among loci, unbiased heterozygosity ($h_i$) within locus, effective number of alleles ($N_e$) and polymorphism information content (PIC) as well as the unbiased average heterozygosity (H) among loci in the populations were calculated using the generated allele frequencies by each marker. Frequencies of microsatellites markers were used to estimate heterozygosities and genetic distances. The nearest distance (0.119) was observed between the C and Y strains. The generated unbiased average heterozygosity among loci in each population was integrated to the global formula of CPD and the result demonstrated that the CPD within the six chicken populations was 99.461%.

• (The)Study of the Eastern Classic
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• no.41
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• pp.187-209
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• 2010

This thesis to be studied conversation by writing between the medical staff of Chosun(朝鮮) and Japan in 1763. Both countries the medical staff and intellectuals meet that communication, confrontation and conflict, exchanges and cooperation in 18C. They met greeting and sing in chorus. Chosun keep checking in western medicine of Japan. They are compared to customs of two countries. Also Japanese increase interest in the Hangeul(한글). Confrontation and conflict resulted from history recognition and difference of viewpoint of two countries. Especially Kokugaku(古學) have many influence on this situation. So battle come and go to study of Ogyu Sorai(荻生?徠) and Dajai Jun(太宰純). But this situation includes Mutual misunderstanding. Because of limitation on conversation by writing. Exchanges and cooperation take shape on the medical staff that a process of ginseng(人蔘), medical treatment. And two countries promote goodwill that method of buying books in Japan and medical treatment. In conclusion, intellectuals of Chosun and Japan have some misunderstanding and distrust. but they are communication with Chinese writing that east asian's common language. Also exchange its views and information.

• Korean Journal of Breeding Science
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• v.43 no.3
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• pp.177-179
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• 2011

A new soybean cultivar 'Daewang' was released by Agricultural Research & Extension Services, Gangwon Province in 2008. The Goals of breeding the variety was for large seed size, high yield, lodging tolerance and resistance to diseases such as soybean mosaic virus (SMV) and bacterial pustule. 'Daewang' was derived from the cross of GWS91, which has yellow seed coat, large seed size and late maturity, and 'Seokryang-putkong', which has large seed size and early maturity. The preliminary, advanced and regional yield trials for evaluation and selection were carried out from 2002 to 2007. It has a determinate growth habit with purple flower, yellow seed coat, yellow hilum and large seed weight (33.6 g per 100 seeds). The maturity date of 'Daewang' is 16 days later than the 'Taekwang'. It has a high content of total isoflavone ($1,851{\mu}g/g$). The average yield of 'Daewang' was 2.68 MT/ha in the regional yield trials (RYT) carried out in four locations in Gangwon province from 2004 to 2007 which was 4 percent higher than the check cultivar 'Taekwang'.