• 한국임상수의학회지
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• 제17권2호
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• pp.443-449
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• 2000

A three-year-old male jindo with generalized skin lesions (including seborrhea, hyperk- eratosis, alopecia, papules, and ecchymoses), pruritus lymph node enlargement, and fever was brought to Veterinary Teaching Hospital, College of Veterinary Medicine, Chungbuk National Uni- versity. There were no laboratory findings for parasites and fungi in the hair and skin But, the com- plete blood counts (CBC) showed leukocytosis and severe cosinophilia, It was suspected to be an inflammatory and allergic dermatitis. Thus, prednisoIone (0.5 mg/kg PO, BID for 1 week) and ampi- cillin (10 mg/kg PO, BID for 1 week given. One week later, pruritus and ecchymoses were reduced. These treatments were repeated for 7 day again. Three months later, the dog was presented again due to the relapse and exacerbation of the clinical signs. The signs were as follows; severe pru- ritus, vesicobullous skin lesions, anorexia, emaciation, lameness, and welling of carpal joints that showed inflammatory skin lesion and draining of synovia-like fluid. The values of WBC counts were returned to normal ranges. In contrast, eosinophilia was still observed. Coombs test for patient RBC and serum were negative. Hypoalbuminemia (2.5g/dl) was shown by serum chemistry. The uri- nalysis revealed and presence of leukocytes. Luxation finding of right radial carpal joint by polyarthritis was shown in radiography of affected joints.Lupus eryhematosus(LE) cells also appeared in peripheral blood and synovial fluid of affected joints. Definitely, antinuclear antibody (ANA) of patient serum using feline peripheral blood mononuclear cells was detected by all immu- nofluorescence. Based on these findings such as sedum ANA-Positive. major signs (skin disease, non- erosive polyarthritis with soft tissue swelling. and proteinuria), minor signs (fever), and LE cell-pos- itive, a diagnosis of systemic lupus crythematosus (SLE) was mad\ulcorner in this dog. The dog with SLE was administered with Pre(2.0 mg/kg PO, BID for first 4 week and then QOD) to inhibit the production of autoantibodies and with ampicillin (10 mg/kg PO, BID for first 4 weeks and then QOD) to prevent the secondary infection. The condition of this dog was monitored every 2 weeks by physical examinations, radiography, CBC, serum chemistry and urinalyais. At 8th week of treat- ment, the state of SLE evaluated by physical examinations and laboratory findings was markedly improved except for proteinura.

• 한국약용작물학회지
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• 제23권3호
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• pp.223-230
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• 2015

To study the effect of crop rotation on the control of ginseng root rot, growth characteristics and root rot ratio of 2-year-old ginseng was investigated after the crops of 18 species were cultured for one year in soil contaminated by the pathogen of root rot. Fusarium solani and Cylindrocarpon destructans were detected by 53.2% and 37.7%, respectively, from infected root of 4-year-old ginseng cultivated in soil occurring the injury by continuous cropping. Content of $NO_3$, Na, and $P_2O_5$ were distinctly changed, while content of pH, Ca, and Mg were slightly changed when whole plant of crops cultured for one year were buried in the ground. All of EC, $NO_3$, $P_2O_5$, and K were distinctly increased in soil cultured sudangrass, peanut, soybean, sunnhemp, and pepper. All of EC, $NO_3$, $P_2O_5$, and K among inorganic component showed negative effect on the growth of ginseng when they were excessively applied on soil. The growth of ginseng was promoted in soil cultivated perilla, sweet potato, sudangrass, and welsh onion, while suppressed in Hwanggi (Astragalus mongholicus), Deodeok (Codonopsis lanceolata) Doraji (Platycodon grandiflorum), Gamcho (Glycyrrhiza uralensis), Soybean. All of chicory, lettuce, radish, sunnhemp, and welsh onion had effective on the inhibition of ginseng root rot, while legume such as soybean, Hwanggi, Gamcho, peanut promoted the incidence of root rot. Though there were no significant correlation, $NO_3$ showed positive correlation, and Na showed negative correlation with the incidence of root rot.

• 한국약용작물학회지
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• 제23권3호
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• pp.198-206
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• 2015

This study was conducted to investigate the effects of sowing density, number of seeds sown per hole, and thinning treatment on growth characteristics and disease occurrence in Panax ginseng under direct sowing cultivation in a blue plastic greenhouse. Seedling were grown from 2 or 3 seeds sown, and the healthiest was only retained, while the rest were thinned out at the foliation stage. $NO_3$-N, $P_2O_5$, and organic matter content differed significantly between growth conditions in the plastic greenhouse and in conventional shade in the soil. Disease also tended to be higher in the conventional shade than in the plastic greenhouse. Plant height and stem length showed an increasing trend with increasing sowing density and number of seeds sown per hole. However, these measures noticeably decreased when thinning treatment was conducted. Growth of the subterranean part of ginseng was not markedly influenced by sowing density, the number of seeds sown per hole, or thinning treatment. Root weight, which is an important factor in yield, was significantly affected by the number of seeds sown and thinning treatment. Interestingly, root weight tended to be higher in the thinning treatment plot than the untreated control plot. Damping-off and root rot increased noticeably as the number of seeds sown increased. Disease also tended to be substantially higher in the thinning treatment plot than the untreated control. However, physiological disorder of the plants did not vary with sowing density, the number of seeds sown, or thinning treatment.

• 한국약용작물학회지
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• 제23권5호
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• pp.379-384
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• 2015

Background : Considerable time and effort is required to develop new Panax ginseng varieties. Ginseng breeders have been developing techniques to shorten the breeding cycle to resolve this problem. In this study, we investigated the effects of adding $GA_3$ and alternating temperature (AT, $2^{\circ}C{\rightarrow}-2^{\circ}C{\rightarrow}2^{\circ}C$) on breaking bud dormancy in the varieties (Chungsun and Sunun) of ginseng root. Methods and Results : The $GA_3$ soaking treatment and AT were applied to one year old roots, which greatly accelerated the emergence of new buds. In one year old roots, new buds emerged from the 4th day post transplanting and after breaking dormancy with $GA_3$ and AT treatments. The emergence of new buds was completed within two weeks. The rate of bud emergence for Chungsun was 60% - 98% over 15 - 60 days after the AT and $GA_3$ treatments. The emergence rate of Sunun was 46% - 92%. Normal growth of the ginseng seedling was observed in spite of the early breaking of bud dormancy by combined $GA_3$ and AT treatments. Conclusions : $GA_3$ and AT treatments shortened the dormancy period and facilitated the stable emergence of ginseng seedlings. However, some plants suffered deformities and early sprouting owing to the combined $GA_3$ and AT treatments. Early sprouting was free from dormancy after leaf fall from the of aerial part of the plant.

• 한국약용작물학회지
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• 제24권3호
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• pp.207-213
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• 2016

Background: This study aimed to investigate the flowering and fruits formation characteristics of Korean Panax ginseng varieties. The results will provide basic data for ginseng seed production and breeding program. Methods and Results: The characteristics investigated included flowering date, seed setting rate, seed type and seed production. The ginseng variety Chungsun had the earliest emergency and flowering dates, whereas Sunhyang showed late emergence and flowering dates. The emergence date of Chunpoong was not later than that of the other varieties, but the flowering date was delayed. The seed setting rate was 64.6%, 75.8%, 78.5% and 74.4% for three, four, five and six-year-old varieties, respectively. The ratio of double seed (RD) for Sunhyang and Chungsun were higher than those for the others, whereas the RD for Chunpoong was the lowest. Yunpoong and Sunone had many stems per plant and a high seed production rate. Seed production was 21.7, 67.7, 74.4 and 89.0kg/10 a in three, four, five and six-year-old varieties, respectively. Conclusions: The emergence date ranged from April 15 to 25, and the flowering date was from May 10 to the 19 for the new ginseng varieties. The average seed multiplication of the ginseng varieties was about 8.5 and 21.1 times a year for varieties in which, seed-production occurs once a year for over four years and four times over six years, respectively.

• 한국약용작물학회지
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• 제21권6호
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• pp.444-454
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• 2013

The development of random amplified polymorphic DNA (RAPD) and expressed sequence tag-derived simple sequence repeats (EST-SSRs) provided a useful tool for investigating Korean ginseng genetic diversity. In this study, 18 polymorphic markers (7 RAPD and 11 EST-SSR) selected to assess the genetic diversity in 31 ginseng accessions (11 Korean ginseng cultivars and 20 breeding lines). In RAPD analysis, a total of 53 unique polymorphic bands were obtained from ginseng accessions and number of amplicons ranged from 4 to 11 with a mean of 7.5 bands. Pair-wise genetic similarity coefficient (Nei) among all pairs of ginseng accessions varied from 0.01 to 0.32, with a mean of 0.11. On the basis of the resulting data, the 31 ginseng accessions were grouped into six clusters. As a result of EST-SSR analysis, 11 EST-SSR markers detected polymorphisms among the 31 ginseng accessions and revealed 49 alleles with a mean of 4.45 alleles per primer. The polymorphism information content (PIC) value ranged from 0.06 to 0.31, with an average of 0.198. The 31 ginseng accessions were classified into five groups by cluster analysis based on Nei's genetic distances. Consequently, the results of ginseng-specific RAPD and EST-SSR markers may prove useful for the evaluation of genetic diversity and discrimination of Korean ginseng cultivars and breeding lines.

• 한국약용작물학회지
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• 제25권3호
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• pp.175-182
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• 2017

Background: Ginseng is a perennial crop grown for more than four years in the same place. Therefore, it is highly affected by the soil environment, especially nutrients in the soil. The present study was carried out to investigate to the influence of boron and iron concentrations on the physiological status, growth, and mineral uptake of ginseng to obtain the basic information for diagnosing a physiological disorder in ginseng plants. Methods and Results: The boron and iron concentrations were controlled at 3, 30, 150, 300 and 2, 20, 100, $200mg/{\ell}$, respectively. When treated with $150mg/{\ell}$ of boron, the ginseng plants showed yellowing or necrosis symptoms at the edge or end of their leaves. Compared with the $3mg/{\ell}$ treatment, the root weight decreased by 13 and 24% in the 150 and $300mg/{\ell}$ treatments, respectively. When treated with $20mg/{\ell}$ of iron, the ginseng plants showed yellowing between the veins of the leaves followed by the formation of brown spots. The root weight gradually decreased with increasing iron concentration. Approximately 55% decrease in root weight was observed upon treatment with $200mg/{\ell}$ of iron. Conclusions: The boron toxicity occurs in the leaves of ginseng at the boron concentration of approximately 1,900 mg/kg or more. The iron toxicity occurs at the iron concentration of approximately 120 mg/kg for leaves and 270 mg/kg for roots.

• 대한공간정보학회지
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• 제24권3호
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• pp.59-66
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• 2016

2011년 발생한 서울시 우면산의 토석류는 과거 산간지역 피해와는 달리 도심지역에서 큰 피해가 발생하였다. 따라서 산사태 및 토석류는 산악지역과 도심지역에 관계없이 다양한 지역에서 빠른 속도로 발생하여 엄청난 피해를 유발시키기 때문에 많은 연구자들은 토석류의 영향범위를 예측하고 피해를 최소화하기 위해 노력하고 있다. 토석류의 영향범위 예측을 위한 가장 핵심적인 부분은 복잡한 3차원 지형에서의 토석류 거동 및 퇴적 메커니즘을 이해하여야 한다. 그리고 퇴적 메커니즘을 이해하기 위해서는 토석류의 거동에 따른 에너지량과 침식량이 산정되어야 한다. 하지만 기존에 개발된 토석류 모델들은 토석류의 침식량을 산정하는데 한계가 있었다. 따라서 본 연구에서는 2011년 도심지의 대규모 토석류가 발생한 서울시 우면산 지역을 대상으로 항공사진, 항공 LiDAR 자료로부터 생성된 토석류 피해 전과 후의 DEM을 활용하여 토석류의 피해규모를 산정하였으며, 에너지 이론을 기반으로 하여 침식량을 산정할 수 있는 토석류 거동 해석 모델을 개발하여 비교하였다. 또한 동일지역에 대하여 기존의 토석류 모델(RWM, Debris 2D)도 함께 시뮬레이션 하여 종합적으로 토석류 지역을 비교 분석하였다.

• 식물분류학회지
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• 제41권4호
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• pp.398-414
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• 2011

소백산 국립공원 지역(북위 $36^{\circ}50^{\prime}-37^{\circ}50^{\prime}$, 동경 $128^{\circ}20^{\prime}-128^{\circ}43^{\prime}$)에 자생하는 식물상을 밝히고 주요 식물들의 분포를 파악하였다. 2005년 4월부터 2011년 10월까지 총 27회에 걸친 현지조사를 실시한 결과 소백산 국립공원의 관속식물은 112과 429속 756종 4아종 91변종 18품종의 총 869분류군으로 정리되었다. 이 중 기존의 조사에서는 발견되지 않았으나 본 조사에서 최초로 밝혀진 분류군은 68분류군이었다. 소백산 국립공원에서 자생하는 식물들 중에는 한국 특산식물 25분류군, 산림청 지정 희귀식물 18분류군, 환경부 지정 멸종 위기 야생식물 II급 3분류군, 식물구계학적 특정식물 중 III등급 이상에 해당하는 75분류군 등이 생육하고 있었다. 또한 소백산 국립공원 지역이 한반도 분포의 남한계인 식물로 구실바위취, 갈퀴현호색, 왜방풍, 종둥굴레 등이, 북한계인 식물로 노각나무가 확인되었으며, 귀화식물은 53분류군이 조사되었다.

• 통상정보연구
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• 제15권4호
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• pp.437-454
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• 2013

인터넷의 급속한 발전으로 인해 온라인상에서 다양한 분야에 걸쳐 정보교류가 활발해졌고, 온라인에 관련된 정보뿐만 아니라 전통적인 구전에 의존하던 오프라인에 관련된 정보도 온라인에서 습득하고 있는 추세이다. 갈수록 치열해지는 병원간 경쟁 환경에서 소비자에게 병원에 대한 느끼는 감정은 병원의 평가와 선택에 있어서 중요한 역할을 한다. 어떤 방식으로 온라인 정보전달을 통해서 소비자에게 접근해야 적절한 감정이 유발될 수 있는가는 매우 중요한 문제이다. 즉, 자기 병원에 대한 어떤 점을 e-비즈니스 마케팅을 통해 부각시켜야 병원에 평가나 선택에 유용한 감정이 의료소비자에게 유발될 수 있는가는 중요한 문제라 할 수 있겠다. u-헬스케어 경쟁시대를 맞아 국내 대형병원들은 SNS 미디어를 병원경영과 홍보마케팅에 적극 활용하고 있는 추세다. 본 연구는 마케팅 활용 관점에서 국내 Big 5로 통하는 메이져 병원 중 e-비즈니스 마케팅을 가장 활발하고 이용하고 있는 삼성서울병원, 세브란스 병원, 성모병원의 SNS 채널들의 특징과 기대되는 성과들을 사례 분석을 통해 비교 분석하고, 마케팅 활동 목적과 방향에 따라 각 채널들을 어떻게 독자적, 혹은 통합적으로 활용하여 마케팅 성과를 극대화시킬 수 있을지에 관한 전략적 틀과 시사점을 제시하고자 하였다.