• Journal of Oriental Neuropsychiatry
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• v.21 no.4
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• pp.1-11
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• 2010

Objectives : The purpose of this study was investigated that correlation between Temperament and Character Inventory(TCI) and Beck Depression Inventory (EDI). State-Trait Anxiety Inventory(STAI) in traffic accident patients. Methods: We investigated 30 cases of traffic accident patients. The patients answered that questionnaire about temperament. character and depression. anxiety. TCI and BDI. STAI were used to get to know that answers. Results: Depression is positive correlated with novelty seeking and harm avoidance in temperament. In character. depression is negative correlated with self directedness, and positive correlated with self-transcendence. Anxiety is positive correlated with harm avoidance in temperament. and negative correlated with self directedness. Conclusions : The results of correlation between TCI and BD I. STAI in traffic accident patients were consistent with previous studies in general person.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.6 no.1
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• pp.18-33
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• 1995

The Purpose of this article is to identify the specific characteristics of borderline disorder in adolescence to conceptualize the borderline state as an adolescent process different from borderline personality disorder in adult, and to classify them according to it's unique clinical feature, porcess and outcome. The development of borderline disorder in adolescent, epidemiology, comorbid disorders and differential diagnosis, pre-existing sub-classification systems, and etiology in theories of psychodynamics, biological theories, experimental studies, and follow-up studies are reviewed. The authors conceptualize the adolescent borderline state include all clinical states generated by re-emergence of unresolved rapproachement conflicts in adolescent, and propose that there are four subgroups in adolescent borderline state. (1) Borderline state as an adolescent process. (2) Borderline state associated with psychotic disorders (3) Borderline state as an initial stnge of typical borderline personality disorder (4) Borderline state associated with organic problems. Conceptually, borderline state in adolescence is not a simple continuation of primary failure of separation-individuation but a struggle for mastering unresolved separation-individuation conflicts in adolesance i.e., the second separation-individuation state, and if it fails this time, the struggle might continue into adult life as borderline personality disorder.

• Biomedical Science Letters
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• v.2 no.1
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• pp.21-30
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• 1996

MAP kinases are a family of serine/threonine specific protein kinases becoming activated in response to different proliferative stimuli by phosphorylation at both threonine and tyrosine residue. Present study shows that MAP kinase was purified from P388 murine leukema cells by SP sephadex C-50, phenyl superose and Mono Q column chromatography and identified with anti-ERKl antibody by western blotting. Immnublotting analysis to the crude extract of P388 cell lysate shows 44 kD and other minor bands but partial purified fraction eluted from phenyl supherose column have 44kD and 66 kD isoform. Subcloned GST-fusion protein from N-terminal of $p56^{kk}$ was tested as a substrate for MAP kinase phosphorylation. It was showed that the wild type and mutant forms(S42A) were fully phosporylated by purified MAP kinase fraction as com-pare with the other mutant form(S59A). This finding suggest that those GST-fusion proteins may be used as substrate for the in vitro test of MAP kinase.

• Korean Journal of Biological Psychiatry
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• v.17 no.4
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• pp.203-209
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• 2010

Objectives : Increasing evidence suggests the presence of neurobiological bases for temperamental characteristics in humans. Brain correlates of harm avoidance(HA) have been most extensively studied using functional and structural brain imaging methods due to its potential link with anxiety and depressive disorders. To date, however, we are not aware of any reports that have examined the potential relationship between HA levels and regional cortical thickness. The aim of the current study is to examine the cortical thickness which is associated with HA temperament in healthy young subjects. Methods : Twenty-eight young, healthy individuals(13 men and 15 women, mean age, $29.4{\pm}6.3$ years) were screened for eligibility and administered the Korean version of the Cloninger's Temperament and Character Inventory and underwent high-resolution structural magnetic resonance imaging scanning. Results : HA was associated with cortical thickness in the right superior frontal cortex and in the left parietal cortex, adjusted for age and sex and corrected for multiple comparisons using the permutation testing method. Conclusion : Individual temperamental differences in HA are associated with structural variations in specific areas of the brain. The fact that these brain regions are involved in top-down modulations of subcortical fear reactions adds functional significance to current findings.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.17 no.2
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• pp.124-130
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• 2006

Objectives : The objective of this study was to evaluate the differences in patterns of temperament and character, as assessed by the Junior Temperament and Character Inventory (JTCI), between the children with attention-deficit/hyperactivity disorder (ADHD) and the control group in a community sample. In addition, we examined the potential differences on JTCI profiles according to the ADHD subtypes. Methods : Parents of 185 ADHD subjects (mean age $9.0{\pm}1.7$ years), as diagnosed by the DISC-IV, and 185 age- and gender-matched comparison children have completed the parent's version of the JTCI. Results : The ADHD group scored significantly higher in Novelty Seeking and lower in Persistence than the comparison group on JTCI. However, there were no significant differences in the temperament or character profiles by the ADHD subtypes. Conclusion : The results of this study suggest that the temperamental factors of higher Novelty Seeking and lower Persistence are related to ADHD. The temperament or character profiles in this study do not provide support for the distinctiveness of the ADHD subtypes.

• Korean Journal of Biological Psychiatry
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• v.17 no.3
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• pp.136-144
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• 2010

Objectives : The $2^{nd}$ to $4^{th}$ digit length(2D : 4D) ratio reflects the amount of exposure and sensitivity to the prenatal sex hormone and it is considered to be the most convenient and useful way to understand the influence of sex hormone in the determination of human behavioral traits. This study was carried out to find the correlation between the 2D : 4D ratio and characteristics of temperament and character in Korean university students. We assumed that 2D : 4D ratio would show a strong correlation with temperament which is defined to be an inclination of an automatical emotional response to a stimulus. Methods : Participants were 104 university students who completed 2 self-report measures : Temperament and Character Inventory(TCI), Temperament Test. We examined the 2D : 4D ratio of each subject by measuring the lengths of the $2^{nd}$ and $4^{th}$ fingers using a photocopy measurement. We performed statistical analyses using correlation test and t-test to examine the relationship between 2D : 4D ratio and psychological characteristics. Results : We found out the typical sex difference in 2D : 4D ratio. Women had significantly higher 2D : 4D ratio than men. TCI-Character factor(TCI-C) didn't show any significant correlation with the 2D : 4D ratio. TCI-Tempterament factor(TCI-T) and the item of Temperament Test showed a significant correlation with the 2D : 4D ratio. In correlation analysis of the total group including all women and men, the 2D : 4D ratio showed a significant positive correlation in a subscale(shyness with stranger) of harm avoidance scales in TCI-T. In correlation analysis of women's group, the 2D : 4D ratio showed a significant positive correlation in two subscales( fear of uncertainty) and[shyness to stranger] of harm avoidance scales in TCI-T. In correlation analysis of men's group, the 2D : 4D ratio showed a significant negative correlation with a sanguine temperament item of the Temperament Test. Conclusion : The results suggest that the amount of exposure to sex hormone in the prenatal period seems to have an impact on the determination of temperament and characteristics.

• Journal of Oriental Neuropsychiatry
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• v.23 no.4
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• pp.95-106
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• 2012

Objectives : The purpose of this study is to study the personality traits of Sasang constitutions by comparing the profiles of Temperament and Character Inventory (TCI) and Eysenck Personality Questionnaire (EPQ). Methods : A total of 110 healthy people (20 to 40 years old), except for 2 Taeyangin (TY type), were analyzed; 45 Taeeumin (TE type), 32 Soyangin (SY type), and 31 Soeumin (SE type). A Sasang constitutional medicine specialist diagnosed the Sasang constitution after analyzing the result of a Two Step Questionnaire for Sasang Constitution Diagnosis (TS-QSCD), the external appearance, temperament and symptoms. The dimensions of TCI and EPQ were compared among the different Sasang constitutions, using an analysis of variance, and correlations between TCI and EPQ were analyzed by a Pearson correlation method. Results : Among the four temperament dimensions of TCI, SY type showed a significantly higher score than the SE type in Novelty Seeking. SE type showed significantly higher score than TE and SY type in Harm Avoidance. SY type showed significantly higher score than SE type in Reward Dependence. TE and SY type showed significantly higher score than SE type in Persistence. There were no significant differences in the character dimensions of Self-directness, Cooperativeness and Self-Transcendence. Among the seven dimensions of EPQ, TE and SY type showed significantly higher score than SE type in Extraversion. SE type showed significantly higher score than SY type in Lie. SY type showed significantly higher score than TE and SE type in Impulsiveness. Conclusions : The results demonstrated that there are some significant differences of personality traits among Sasang constitutions. This could help diagnose and understand each Sasang constitution.

• Korean Journal of Psychosomatic Medicine
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• v.15 no.1
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• pp.35-43
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• 2007

Objectives : Recently, many authors investigated the relation of temperament and character to seasonality and the genetic factors in seasonality and personality. In this study, we investigated the relation between personality structure obtained from the psychobiological Temperament and Character Inventory (TCI) and self-reported seasonal variations in mood and behavior measured by the Seasonal Pattern Assessment Questionnaire (SPAQ). Methods : 600 high-school students who live in Seoul of Korea, were participated in this study. Subjects were surveyed with the Korean translation of the SPAQ of Rosenthal, an instrument for investigating mood and behavioral changes with respect to the seasons of the you. Korean version of the TCI of Cloninger was also used for assessment of personality. Results : Female students were significantly higher scores on harm avoidance, reward dependence, and cooperativeness than male students who had significant higher scores on persistence and self·transcendence than the formers. GSS were showed positive correlation with harm avoidance and self-transcendence, and negative correlation with cooperativeness and self-directedness. By employing logistic regressions, the regression coefficients of SAD were significantly negative in SD, and positive in ST. Also, the regression coefficients of S-SAD were significantly negative in CO, and positive in ST. Those with GSS at least 11 were significantly higher mean ST values compared to the remaining individuals, and those with worst in winter were significantly lower mean CO values compared to the remaining individuals. Those who considered the seasonality as a problem at least to a moderate degree were associated with high HA and ST. Conclusion : We add the evidence that the seasonality is related to the temperament and character. Although there have been many reports about the seasonality in relation to the temperament and character in foreign countries, there has been very limited report from Korea before. We hope that this result would be a helpful in the clinical field in Korea.

• Journal of the Korean Society of School Health
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• v.23 no.2
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• pp.181-191
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• 2010

Purpose: The purpose of this study is to analyze the drinking status and to identify the impacts of depression, temperament, characteristic on drinking status in the vocational high school students. Methods: By using stratified sampling, 416 vocational high school students in Gangwon Do were selected and surveyed through self -administered questionnaires. Data were analyzed by SPSS 12.0 using $x^2$-test, t-test, ANOVA, Pearson correlation coefficient and multiple regression. Results: 88% of students had experienced of drinking. Depression was observed 59.1% of students from light to severe depression score. There was a positive correlation among drinking, the school records, novelty seeking, reward dependence and persistence. Also, there was a negative correlation among drinking, economic status, harm avoidance. The significant predictors of drinking were school records, depression, novelty seeking and persistence. Conclusion: These results suggest that vocational high school students who have the factors identified in this study are regarded as having the potential to drink. The results of this study can provide the information for the development of the health promotion program.

• Journal of Korean Academy of Rural Health Nursing
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• v.2 no.1
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• pp.14-23
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• 2007

Purpose: The purpose of this study was to analyze the smoking behaviors and to identify the impact of depression, temperament, and characteristics of smoking experience on rural adolescents. Method: A survey using a self-administered questionnaire was done of 310 rural high school students. Using SPSS 12.0, Pearson correlation coefficients and multiple regression were used to analyze the data. Results: The smoking rate of rural high school students was higher than that of the national rate for this age group. Serious depression was observed in the rural high school students. There was a positive correlation among smoking experience, school records, novelty seeking and a negative correlation between smoking and cooperativeness. The significant predictors of smoking experience were type of school, satisfaction with school, school records, novelty seeking, reward dependence and cooperativeness. These factors accounted for 38.9% of variances in the smoking experience of rural adolescents. Conclusion: These results suggest that adolescents who exhibit factors identified in this study are regarded as having the potential to smoke, and this result proposes the basis for program development for the prevention of smoking and smoking cessation.