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Dopamine Transporter Density of the Basal Ganglia Assessed with I-123 IPT SPECT in Methamphetamine Abusers (Methamphetamine 남용자에서 I-123 IPT를 이용한 기저신경절 도파민운반체 밀도의 평가)

  • Lee, Joo-Ryung;Ahn, Byeong-Cheol;Kewn, Do-Hun;Sung, Young-Ok;Seo, Ji-Hyoung;Bae, Jin-Ho;Jeong, Shin-Young;Lee, Sang-Woo;Yoo, Jeong-Soo;Lee, Jae-Tae;Chi, Dae-Yoon;Lee, Kyu-Bo
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.6
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    • pp.481-488
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    • 2005
  • Purpose: Functional imaging of dopamine transporter (DAT) defines integrity of the dopaminergic system, and DAT is the target site of drugs of abuse such as cocaine and methamphetamine. Functional imaging the DAT may be a sensitive and selective indicator of neurotoxic change by the drug. The aim of the present study is to evaluate the clinical implications of qualitative/quantitative analyses of dopamine transporter imaging in methamphetamine abusers. Materials and Methods: Six detoxified methamphetamine abusers (abuser group) and 4 volunteers (control group) were enrolled in this study. Brain MRI was performed in all of abuser group. Abuser group underwent psychiatric and depression assessment using brief psychiatric rating scale (BPRS) and Hamilton depression rating scale (HAMD), respectively. All of the subjects underwent I-123 IPT SPECT (IPT SPECT). IPT SPECT image was analysed with visual qualitative method and quantitative method using basal ganglia dopamine transporter (DAT) specific/non-specific binding ratio (SBR). Comparison of DAT SBR between abuser and control groups was performed. We also performed correlation tests between psychiatric and depression assessment results and DAT SBR in abuser group. Results: All of abuser group showed normal MRI finding, but had residual psychiatric and depressive symptoms, and psychiatric and depressive symptom scores were exactly correlated (r=1.0, p=0.005) each other. Five of them showed abnormal finding on qualitative visual I-123 IPT SPECT Abuser group had lower basal ganglia DAT SBR than that of control ($2.38{\pm}0.20\;vs\;3.04{\pm}0.27$, p=0.000). Psychiatric and depressive symptoms were negatively well correlated with basal ganglia DAT SBR (r=-0.908, p=0.012, r=-0.924, p=0.009). Conclusion: These results suggest that dopamine transporter imaging using I-123 IPT SPECT may be used to evaluate dopaminergic system of the basal ganglia and the clinical status in methamphetamine abusers.

Algorithms for Computing Inverses in Finite Fields using Special ONBs (특수한 정규기저를 이용한 유한체위에서의 역원 계산 알고리즘에 관한 연구)

  • Kim, Yong-Tae
    • The Journal of the Korea institute of electronic communication sciences
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    • v.9 no.8
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    • pp.867-873
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    • 2014
  • Since the computation of a multiplicative inverse using MONB includes many squarings and thus calculating inverse is expensive, we, in this paper, propose a low cost inverse algorithm requiring $nb(2^nm-1)+w(2^nm-1)-2$ multiplications and $2^n-1$ squarings to compute an inverse in $GF(2^{2^nm})^*$ using special normal basis over $GF(2^{2^n})$, and give some implementation results using the algorithm and, show that the timing results of our implementation is faster than that of Itoh et al.'s method.

Modified Multi-bit Shifting Algorithm in Multiplication Inversion Problems (개선된 역수연산에서의 멀티 쉬프팅 알고리즘)

  • Jang, In-Joo;Yoo, Hyeong-Seon
    • The Journal of Society for e-Business Studies
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    • v.11 no.2
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    • pp.1-11
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    • 2006
  • This paper proposes an efficient inversion algorithm for Galois field GF(2n) by using a modified multi-bit shifting method based on the Montgomery algorithm. It is well known that the efficiency of arithmetic algorithms depends on the basis and many foregoing papers use either polynomial or optimal normal basis. An inversion algorithm, which modifies a multi-bit shifting based on the Montgomery algorithm, is studied. Trinomials and AOPs (all-one polynomials) are tested to calculate the inverse. It is shown that the suggested inversion algorithm reduces the computation time up to 26 % of the forgoing multi-bit shifting algorithm. The modified algorithm can be applied in various applications and is easy to implement.

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A minimizing method of baseline wandering using a difference signal in ECG (심전도 차신호를 이용한 기저선 변동의 최소화 방법)

  • Ju, Jangkyu;Lee, Ki Young
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.1 no.1
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    • pp.7-12
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    • 2008
  • This paper studies a method to minimize the baseline wandering that make hard to extract R-wave in ECG. This method uses a difference signal between ECG and ascending slope tracing waves to minimize the baseline wandering. When the slope of ECG signal maintains the value or falls, the ascending slope tracing wave follows ECG signal directly, and this wave holds that value of ECG signal when the slope begins to rises in a certain time(=hold time). After this hold time, this wave traces ECG signal again. This method has been applied to MIT/BIH database to verify its efficacy and validity in practical applications.

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Dynamic Correction of DES Model Constant for the Advanced Prediction of Supersonic Base Flow (초음속 기저유동의 우수한 예측을 위한 DES 모델상수의 동적 보정)

  • Shin, Jae-Ryul;Choi, Jeong-Yeol
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.38 no.2
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    • pp.99-110
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    • 2010
  • The DES analysis of strong compressibility flow, LES mode is intentionally performed in boundary layer with the conventional empirical constant $C_{DES}$ value of 0.65. In this study, an expression is suggested to determine the $C_{DES}$ value dynamically by using a distribution function of the ratio of turbulence length scale and wall distance which is used in S-A DDES model for RANS mode protection. The application of the dynamic $C_{DES}$ presents better prediction than previous results those used constant but different $C_{DES}$ values.

Image Compression and Edge Detection Based on Wavelet Transforms (웨이블릿 기반의 영상 압축 및 에지 검출)

  • Jung il Hong;Kim Young Soon
    • Journal of Korea Multimedia Society
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    • v.8 no.1
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    • pp.19-26
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    • 2005
  • The basis function of wavelet transform used in this paper is constructed by using lifting scheme, which is different from general wavelet transform. Lifting scheme is a new biorthogonal wavelet con-structing method, that does not use Fourier transform for constructing its basis function. In this paper, an image compression and reconstruction method using the lifting scheme was proposed. And this method improves data visualization by supporting a partial reconstruction and a local reconstruction. Approx- imations at various resolutions allow extracting various sizes of feature from an image or signal with a small amount of original information. An approximation with small size of scaling coefficients gives a brief outline of features at fast. Image compression and edge detection techniques provide good frame- works for data management and visualization in multimedia database.

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Performance of Multiuser Detector Based on Radial Basis Function for DS-CDMA Power Line Communication Systems (DS-CDMA 기반 전력선 통신 시스템을 위한 방사형 기저 함수를 이용하는 다중 사용자 검출기의 성능)

  • Hwang, Yu Min;Kim, Jin Young
    • Journal of Satellite, Information and Communications
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    • v.12 no.1
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    • pp.1-5
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    • 2017
  • In this paper, multiuser detector (MUD) based on radial basis function (RBF) is proposed and simulated for a multicode direct sequence/code division multiple access (DS/CDMA) system in a multipath fading channel. The performance of RBF-based MUD is compared with that of many suboptimal multiuser detectors in terms of bit error probability. From the simulation results, it is confirmed that the RBF-based MUD outperforms decorrelating detector, and achieves near-optimum performance under various environments. The results in this paper can be applied to design of MUD for a multicode DS/CDMA system.

Transparent Conductive Polymer Sheets and Films for Electrostatic Discharge (정전기 방지용 투명 전도성 고분자 쉬트 및 필름)

  • 서광석;김종은;김태영;이보현;진영필;박현근
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.07a
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    • pp.219-219
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    • 2001
  • 최근 정전기 방지 및 전자파 차폐재료로 주목받고 있는 전도성 고분자를 절연체 고분자 표면에 코팅하여 정전기 방지 포장용으로 사용되는 투명 대전방지 고분자 쉬트 및 필름을 개발하였다. 현재 사용하고 있는 정전기 방지 포장용 고분자는 폴리스티렌이나 폴리비닐에 카본블랙을 혼합하거나 또는 계면활성제를 표면 에 코팅하여 사용하였다. 그러나 카본블랙을 섞은 경우는 카본입자가 불순물로 작용하여 제품을 오염시키고 검은색 불투명이기 때문에 포장 후 제품을 확인 할 수 없으며 카본 혼합에 따른 기저수지의 물성 약화 가 문제가 되고 있으며 계면활성제를 혼합하거나 코팅하여 사용하는 경우는 시간이 지남에 따라 전도성이 소멸되며 입자가 표면으로 blooming out되어 제품을 오염시키는 단점을 가지고 있다. 본 기술 개발에 의하여 얻어진 투명 전도성 고분자 쉬트 및 필름은 기저수지가 투명할 경우 550nm에서 투명도를 5% 이하로 감소시키며 전도성 물질로 고분자를 사용하기 때문에 영구적인 전도성을 가지며 기저 고분자의 물성을 그 대로 유지 할 수 있는 장점을 가지고 있다. 본 개발품은 전자 부품 및 반도체 포장용 트레이, 캐리어 소재 및 정전기 방지를 필요로 하는 모든 분야에 사용될 수 있으며 전도성 부여 처리기술을 가지고 있기 때문에 포장, 운반 목적 외에 여러 가지 정전기 방지 처리분야에 적용이 가능하다.

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A Study on Speaker Recognition Algorithm Through Wire/Wireless Telephone (유무선 전화를 통한 화자인식 알고리즘에 관한 연구)

  • 김정호;정희석;강철호;김선희
    • The Journal of the Acoustical Society of Korea
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    • v.22 no.3
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    • pp.182-187
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    • 2003
  • In this thesis, we propose the algorithm to improve the performance of speaker verification that is mapping feature parameters by using RBF neural network. There is a big difference between wire vector region and wireless one which comes from the same speaker. For wire/wireless speakers model production, speaker verification system should distinguish the wire/wireless channel that based on speech recognition system. And the feature vector of untrained channel models is mapped to the feature vector(LPC Cepstrum) of trained channel model by using RBF neural network. As a simulation result, the proposed algorithm makes 0.6%∼10.5% performance improvement compared to conventional method such as cepstral mean subtraction.

A analysis of Thin-Straight Monopole antenna on a conducting box Using the Wire-Grid Method (Wire-Grid 방법을 이용한 도체 상자에 부착된 선형 모노폴 안테나 해석)

  • 이승엽;김경재;이영훈;허선종;박한규
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.18 no.11
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    • pp.1669-1676
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    • 1993
  • In this paper, a thin-straight monopole antenna attached to a conducting box is analyzed using a moment method with the pocklington integral expression for the exact Green's function. A modeling of a conducting box is based on a Wire-Grid method for an efficient calculation procedure. A system of linear equation is obtained using the piecewise sinusoidal basis function. And a Junction basis function is enforcing to represent the physical current on the edge of the conducting box. Especially, the junction basis functions are overlapped for the current continuity preserving on the vertexes. Numerical results are obtained for the current distribution on the unified antenna/conducting box system, input impedance and radiation pattern. The results are compared with the known data.

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