• Journal of Pharmacopuncture
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• v.11 no.1
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• pp.149-162
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• 2008

Objectives : The purpose of this study is to investigate the effects of hot pepper extract and capsaicin on the adipogenesis in 3T3-L1 cells, lipolysis in rat epididymal adipocytes and histological changes in porcine adipose tissue. Methods : Inhibiton of preadipocyte differentiation and/or stimulation of lipolysis play important roles in reducing obesity. 3T3-L1 preadipocytes were differentiated with adipogenic reagents by incubating for 3 days in the absence or presence of hot pepper extract or capsaicin ranging from 0.01 to $1mg/m{\ell}$. The effects of hot pepper extract and capsaicin on adipogenesis were examined by measuring GPDH activity and by Oil Red O staining. Mature adipocytes from rat epididymal fat pad was incubated with hot pepper extract or capsaicin ranging from 0.01 to $1mg/m{\ell}$ for 3 hrs. The effects of hot pepper extract and capsaicin on lipolysis were examined by measuring free glycerol released. Fat tissue from pig skin was injected with hot pepper extract or capsaicinCFP ranging from 0.1 to $10mg/m{\ell}$ to examine the effects of hot pepper extract and capsaicin on histological changes under light microscopy. Results : The following results were obtained from present study on adipogenesis of preadipocytes, lipolysis of adipocytes and histological changes in fat tissue. 1. Hot pepper extract and capsaicin inhibited adipogenic differentiation at the concentration of 0.1 and $0.01mg/m{\ell}$, respectively, indicating that capsaicin was more effective in inhibiting adipogenesis than hot pepper extract. 2. Hot pepper extract and capsaicin decreased the activity of glycerol-3-phosphate dehydrogenase(GPDH) at the concentration of 0.1 and $0.01mg/m{\ell}$, respectively, indicating that capsaicin was more effective in inhibiting adipogenic differentiation than hot pepper extract. 3. Hot pepper extract and capsaicin increased glycerol release at the concentration of $0.1mg/m{\ell}$. There was no difference in lipolytic activity between hot pepper extract and capsaicin at the corresponding concentration. 4. Hot pepper extract and capsaicin caused shrinkage of fat cells, resulting in cell death at the concentration of $1.0mg/m{\ell}$, although capsaicin exerted this action over wide area than hot pepper extract. Conclusions : These results suggest that hot pepper extract and capsaicin efficiently inhibited adipogenesis, increased lipolysis of adipocytes and caused to shrink fat cells. Future studies are needed to make use of hot pepper extract pharmacopuncture for the treatment of obesity.

• Journal of Pharmacopuncture
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• v.11 no.1
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• pp.127-141
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• 2008

Objectives : The purpose of this study is to investigate the effects of Chowiseungcheng-tang extracts on the preadipocytes proliferation in 3T3-L1 cell line, lipolysis of adipocytes in rat's epididymal adipocytes and localized fat accumulation of porcine by extraction methods(alcohol and water). Methods : Diminish preadipocytes proliferation and promote lipolysis of adipocytes do primary role to reduce obesity. So, we used 3T3-L1 mouse embryo fibroblasts(preadipocytes) and rat epididymal adipocytes from Sprague-Dawley rats to investigate the effects of Chowiseungcheng-tang extracts on the preadipocytes proliferation, lipolysis of adipocytes. They were treated with 0.01, 0.1, $1.0mg/m{\ell}$ Chowiseungcheng-tang alcohol and water extracts. And for the purpose of investigating the effects of Chowiseungcheng-tang alcohol and water extracts on the localized fat accumulation, we injected 0.1, 1.0, $10.0mg/m{\ell}$ Chowiseungcheng-tang extracts to porcine fat tissues and observed histological changes of them. Results : Following results were obtained from the preadipocytes proliferation and lipolysis of adipocytes and histological investigation of fat tissues. 1. Chowiseungcheng-tang extracts suppressed preadipocytes proliferation on the high dosage(especially $1.0mg/m{\ell}$), and especially alcohol extracts had better effects. 2. The alcohol extracts of Chowiseungcheng-tang decreased the activity of glycerol-3-phosphate dehydrogenase (GPDH) on the concentrations of 0.1, $1.0mg/m{\ell}$. Alcohol extracts had better effects than water extracts. 3. Chowiseungcheng-tang extracts increased lipolysis of adipocytes on the concentrations of 0.1, $1.0mg/m{\ell}$, and especially on the concentration of $1.0mg/m{\ell}$ alcohol extract of Chowiseungcheng-tang had better effect. 4. The water extract of Chowiseungcheng-tang had significant activity to the destruction of porcine fat cell membranes only on the concentration of $10.0mg/m{\ell}$, but alcohol extracts of Chowiseungcheng-tang had it on all concentrations. Conclusions : The alcohol extracts of Chowiseungcheng-tang had much better effects on the preadipoeytes proliferaton, lipolysis of adipocytes and localized fat accumulation than water extracts.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.31 no.1
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• pp.71-86
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• 2013

This study was carried out to find the changed contents and details of the ponds at Jondeokjeong area in the Changdeok Palace, where was modified during the reign of King Gojong(高宗, 1863~1907), and considered the internal context through the diachronic views about royal garden building in the Joseon Dynasty. The results were as belows. First, this study found that the transformed time of the ponds at Jondeokjeong area was the 21th year of King Gojong(1884) based on the pictures taken in the last half of the 19th century and the records of "Gojongsilrok(高宗實錄: Annals of the King Gojong)". Second, this study also found that the remodeled ponds at Jondeokjeong area by King Gojong were followed the landscape of Geoncheong Palace(乾淸宮) and Hiangwon-pond(香遠池) in Gyeongbok Palace because the remodeled ponds of Jondeokjeong area had the spatial organization similar to Hiangwon-pond. Third, the bridge of remodeled ponds at Jondeokjeong area was utilized as the expedient to expand the function of rear garden, which combines the areas of Yungyungdang(演慶堂) and Jondeokjeong. This was the same method that Konchunggung(乾淸宮) in Gyeongbok Palace had occupied the whole area through the Chui-hiang bridge(醉香橋) which connects to the Hiangwonjeong(香遠亭). Fourth, ponds at Jondeokjeong area and Hiangwonjeong that were created during the year of King Gojong promised the use of Yungyungdang and Konchung Palace, and reflected the statuses of the two building-blocks. Lastly, this study concluded the remodeled Jondeokjeong ponds were not only to create the necessary spaces of the landscape for King Gojong, but also to build the space on the context of Huwonjeongdang(後苑政堂: political structure in rear garden), which has been passed down from their ancestors.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.3
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• pp.374-384
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• 1999

Benthic marine algal flora and community structure of Yongho-dong area in Pusan, Korea were investigated seasonally in intertidal and subtidal zones by a quadrat method along 5 transect lines from July 1996 to April 1997. In this area, a total of 99 species including 3 blue-green, 13 green, 26 brown and 57 red algae was found. Among them, 33 taxa, together with dominant Ulva pertusa and Corallina pilulifera, occurred throughout the year. Enteromorpha spp. and Ulva spp. vertically distributed in upper and middle zone, while Simphyocladia latiuscula, Chondria crassicaulis, Corallina pilulifera and Sargassum sup. in lower zones. Biomass per unit area exhibited a wide range of variation, from 1,241 g/$m^2$(spring) to 1,648 g/$m^2$(summer) in fresh weight. Maximum and minimum species diversity were recorded in spring and autumn, respectively. Results of the UPGAM cluster analysis suggest that the examined 5 sites can be divided into two groups, sites exposed to open sea (transects 1, 2, 3) and comparatively sheltered sites (transects 4, 5) faced with the Pusan Harbor. The former group is represented by large brown algae, Sargassum and Hizikia, while Ulva pertusa and Lomentaria species are mainly found in the latter group. A calcareous alga, Corallina pilulifera occurred dominantly in both groups throughout the year. In conclusion, number of species in this area was remarkably reduced as compared to the previous data. This result may suggest probably more change of algal vegetation in future, considering the physical and chemical pollutions loaded in the coastal marine environment of this area.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.4
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• pp.63-68
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• 2010

Utility-Pipe Conduit is, Housing and city effectively accommodate what they absolutely need power, communications, gas, pipeline, water supply, drainage, energy facilities etc, according to expansion of urban infrastructure are derived, several ways to solve problems in, collection facilities in place are maintained and managed facility. If Utility-Pipe Conduit is damaged, as well as national security, because their impact on society as a whole, by introducing large vulnerability in the fire prevention activities and suppression measures and disaster for our situation by introducing measures, comprehensive analysis of the fire risk, it shall establish fire prevention activities and suppression through analysis of Utility-Pipe Conduit design, institutional issues, the problem of fire protection facilities, fire spread phenomenon etc. Because of Utility-Pipe Conduit is an enclosed place, so incomplete combustion due to lack of oxygen supply that there are problem such dark smoke, carbon monoxide etc, toxic combustion products and heat generation and visual impairment is an issue difficult to enter. As well as fire prevention activities, the fire In light of the particularity of the under ground than above ground fire, so this phenomenon is weak fire fighting that fire to become effective fire fighting tactics, basically it is necessary difficulty softening, non-burn softening and prevent combustion expansion of the cable is installed on the Utility-Pipe Conduit, having to considering the specificity of the response command system and relevant organizations to establish an on-site, Structural identification and other information gathering required to record of Response agencies, keep air conditioning system 24 hours and strengthening Virtual Total Training of Response agen

• Journal of Korea Water Resources Association
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• v.48 no.8
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• pp.605-612
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• 2015

The purpose of this study is to compare and analyze design flood estimation methods which are the basis for determining the size of a flood control structure. The result from a flood frequency analysis which is considered as the best way for estimating design flood was assumed as a true value, and a method of simulating runoff and performing frequency analysis of the maximum discharge data were compared with a design storm method. For a comparative analysis of design flood estimation, seven basins (Namgang reservoir basin, Soyanggang reservoir basin, Andong reservoir basin, Seomjingang reservoir basin, Imha reservoir basin, Chungju reservoir basin, Hapcheon reservoir basin) were selected. For the Seomjingang, Hapcheon, and Imha reservoir basins, the method proposed in this study showed better results, whereas the conventional method showed better results for the Namgang, Soyanggang, and Chungju reservoir basins. The results show that the conventional method (the design storm method) is not the best way for estimating design flood and the proposed method can be used as an alternative for small basins.

• Journal of the Korean earth science society
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• v.36 no.6
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• pp.512-519
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• 2015

Although Quaternary marine terraces and onshore paleo-shoreline records provide clues to our understanding for the mode and nature of neotectonics in the Korean peninsula, it cannot be accomplished without knowledge on both independent information of the past sea level records and tectonic deformation field together with precise results of numerical dating for higher terraces. This study reported cosmogenic radionuclides ($^{10}Be$) dating results conducted in higher terraces in the eastern and western coasts of the Korean peninsula. As a result, the measured concentration ratio of $^9Be/^{10}Be$ and the exposure ages were much younger than expected. It implies that either there is possibility of error in experimental processes or the samples experienced a complex exposure history probably included a burial at some stage. Considering the past climatic conditions around the Korean peninsula and a possible complex exposure history after the emergence of marine terrace, the discovery of a suitable study area and a sampling site are an essential part of successful $^{10}Be$ dating technique.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.1
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• pp.34-40
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• 2004

The purpose of this study was to measure the changes of regional cerebral blood flow (rCBF) and blood pressure (BP) in rats, following the intravenous injection of Schizandrae fructus water extract. The measurement was continually monitored by laser-doppler flowmeter and pressure tranducer in anesthetized adult Sprague-Dawley rats for 2 hours to 2 hours and a half through the data acquisition system composed of MacLab and Macintosh computer. The result of this experiment was as followed. Schizandrae fructus increased the changes of rCBF in rats significantly. The rCBF of Schizandrae fructus did not change by pretreated propranolol, atropine, L-NNA and indomethacin. But the rCBF of Schizandrae fructus was increased by pretreated methylene blue. Schizandrae fructus decreased the changes of BP, significantly. The BP of Schizandrae fructus did not change by pretreated propranolol, atropine, L-NNA and indomethacin. But the BP of Schizandrae fructus was decreased by pretreated methylene blue. There results indicated that Schizandrae fructus can increase the rCBF and decrease the BP, that is related to guanylyl cyclase activity.

• Journal of the Korean Geographical Society
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• v.39 no.3
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• pp.344-359
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• 2004

This geographical study is to identify the reality of Nokdun island which was once settled and farmed by our ancestor, but currently the island is do facto under Russia's control. Various historical documents including old maps, current large scale maps and satellite images besides field work were used for full analysis. According to historical records, up until Chosun Dynasty, Nokdun island in the lower Tuman river was one of the frontier fortified base crossed the river for the northern defense as well as seasonal farming for the farmer of Kyounghung border area. Even though the island was unjustly lost to Russia by the Beijing Treaty in the late Chosun period, the whole area of Nokdun was occupied and farmed by sole Koreans until the deportation by Stalin was forcibly measured. In these days due to the change of Tumn river channel and new deposition by river it became very difficult to find the original shape of Nokdun island. However, through intensive field works based on historical records, the research team found out the existence of the old wet-dry fields, old rural farmhouse remnants, and small and medium size of millstones that are supporting the reality of the island. Especially, the team traced a mud fortress presumedly built in the early Chosun period. We believe it might allow to allocate the exact location of Nokdun island in near future.

• Korean Journal of Ichthyology
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• v.12 no.3
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• pp.215-222
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• 2000

Fish fauna of the coastal waters off Taean, Chungchyungnam-do, Korea, was investigated from May 1996 to July 1999. The specimems collected from the three localities were identified into 73 species belonging to 63 genera and 40 families. Of them the largest group was order Perciformes, comprising 35 species and 16 families, and showed 47.9% in total number of species. Chasmichthys gulosus and C. dolichognathus were commonly found from the st. 1, Sebastes schlegeli and Hexagrammos otakii, from the st. 2 and Cynoglossus joyneri, Acanthopagrus schlegeli, Pagrus majar, Chirolophis wui and Pholis fangi from the st. 3 of sampling localities. Porocottus sp. is described on the basis of 2 specimens collected from the st. 1 of sampling localities. The species was distinguished from all the other members of the genus by the following combination of characters: united dorsal fin, scales on trunk above lateral line, cirri on anterior part of lateral line.