• Tuberculosis and Respiratory Diseases
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• v.49 no.1
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• pp.18-29
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• 2000

호흡기 바이러스 감염은 모든 연령층의 천식에 상당한 영향을 미치는 데 영아에서 RSV는 천명을 야기하고 대부분 일시적이나 재발성 일수도 있다. 어릴 때 바이러스 감염은 면역체계 형성에 영향를 미쳐 알러지와 천식의 위험을 완하할 수있다고 한다. 또한 소아와 성인 천식에서 RV같은 감기 바이러스는 천식의 급성 증상을 유발한다. 호흡기 바이러스 감염에 대한 면역반응이, 기관지로 부터 바이러스 제거 기능외에 기도수축과 호흡기 증상에 관여한다고 한다. 이러한 변화가 일어나는 기전은 호흡기 바이러스가 proinflammatory 사이토카인과 매개체 생성을 유도하는 능력과 연관성이 있는 것 같고 이들이 상하기도 호흡기 증상 및 기도반응 변화에 관여하는 것으로 생각된다. 호흡기 바이러스 감염에 대한 면역반응을 요약하면 바이러스 감염으로 상피세포, 내피세포, 과립백혈구가 활성화되며, 상피세포는 사이토카인, 키모카인, 매개체들을 분비하여 항 면역 반응를 주도하다. 이와 같은 상피세포와 다른 기관지 세포들의 조기 활성화로 내피 세포에 유착분자 표현을 증가시켜 백혈구 동원 증가 및 혈관 투과성을 증가시켜 부종과 분비물을 증가시킨다. 바이러스 또는 바이러스 유발 사이토카인에 의해 활성화된 과립 백혈구, 대식세포, T세포들도 기도염증 증가, 기도폐쇄를 야기하고 기도반응을 증가시킨다. 세포독성 임파구에 의한 바이러스 감염세포의 분해, TGF-$\beta$ IL-10 같은 사이토카인에 의해 부분적으로 염증억제, 기도 remoldeling에 의한 기도구조의 재생등이 바이러스 감염후 기관지 기능의 지속적 변화를 결정한다. 끝으로 천식환자에서 RV 감염의 병인에 관한 기본적 문제는 RV감염이 정상인에서는 경한 증상을 나타내는 데 천식환자에서는 왜 심한 임상증상을 나타내는지 아직 완전히 밝혀지지 않았다. 항 바이러스에 대한 면역반응이 천식환자에서 손상되었는지 또는 천식환자에서 RV감염에 의한 중증의 임상증상은 어떤 다른 세포가 관여하는지? 이들에 대한 답은 기도염증이 천식에서 어떻게 조절되는지 또한 바이러스 감염에 의한 악화된 증상을 어떻게 치료할 것인가에 대한 방향을 제시해줄 것이다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1982.05a
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• pp.12-12
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• 1982

We have recently experienced a case of decannulation difficulty resulted from head and thoracic injury. The patient was 21-year-old male who undergone craniectomy and tracheotomy at other hospital about 7 months ago prior to admission On admission, there was swelling in glottic and subglottic region in indirect laryngoscopy and bronchoscopy with fixation of vocal cords in paramedian position. We tried to reestablish an adequate air way with bougination using Jackson esophageal bougie but there was no effect with it. So we performed vertical incision through cricoid cartilage and tracheal rings and insertion of Teflon tube in stenotic lesion for 9 months and removed it. At present time, the patient has been satisfactory corking training course.

• Journal of Yeungnam Medical Science
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• v.12 no.1
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• pp.75-83
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• 1995

Even though phototherapy is an effective means of treating hyperbilirubinemia, adequate binocular shields are essential to prevent light hazard of retina during phototherapy. The phototherapy to young albino rabbits was performed under various conditions; exposured for 12, 24, and 48 hours, continuity or intermittence of irradiation, and use of shields. Although there was no definite pathologic change in indirect ophthalmoscopic examination, severe damage was seen at electron microscopic level. In all experimental groups, swelling and edema of photoreceptor were seen at right after phototherapy. Futhermore, more severe damage was seen in case of intermittent irradiated group and prolong exposed group. In mydriatic eyes, severity of damage was similiar to non mydriatic eyes, but area of retinal damage was more extensive than non-mydriatic eyes. In control group which was protected by binocular shields during phototherapy, no significant abnormality was found.

• Journal of the Korean Orthopaedic Association
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• v.55 no.4
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• pp.354-358
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• 2020

Lipoma arborescens (LA) is a rare lesion that causes joint effusion and pain. LA usually presents as a unilateral knee lesion, and bilateral lesions are extremely rare. LA among adolescent patients is also extremely rare with the disorder having a much higher incidence among adults. This paper reports a 14-year-old boy who was treated for bilateral knee LA. X-rays revealed the characteristic features of LA in both knees, and arthroscopic synovectomy was performed to resect the lesions. Postoperative recovery progressed smoothly, and the patient was eventually relieved of pain and swelling. LA should be considered when adolescent patients present with bilateral pain and swelling, even though this condition is rare in this age group. Furthermore, surgical synovectomy for a complete resection is an appropriate treatment option.

• The Journal of Korean Obstetrics and Gynecology
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• v.35 no.1
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• pp.1-11
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• 2022

Objectives: Management of the postpartum period is important for the health of mothers, and postpartum edema is one of the management targets. In this study, the relationship between the value measured by the device and the postpartum edema sensation was examined to explain the subjective sensation of the mother as an objective value. Methods: Data from 54 cases provided by 24 mothers within 6 weeks postpartum were used in the study. The degree of postpartum edema sensation was measured using a visual analog scale (VAS), and the effect of VAS changes on the body edema index and weight change before and after childbirth was estimated through linear regression analysis. Results: As a result of the regression analysis, when the edema sensation of the mothers VAS increased by 1 point, the Inbody edema index increased by 0.002 points (p=0.000, R²=0.272), and when the VAS increased by 1 point, the weight gain increased by 0.99 kg compared to before pregnancy (p=0.000, R²=0.243), and when VAS increased by 1 point, weight loss decreased by 0.56 kg compared to just before childbirth (p=0.004, R²=0.136). Conclusions: The results of this study, in which the edema sensation of postpartum mothers was statistically significantly related to the edema index and weight change before and after childbirth, showed that the edema sensation complained by the mother could be used as an evaluation index for postpartum edema management in the future.

• The Journal of Dong Guk Oriental Medicine
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• v.11
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• pp.58-65
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• 2008

Objectives : BHT has been commonly used to treatment of brain disorders in Oriental clinic in Korea. The purpose of this study was to determine the inhibitory effect of modified BHT-C extract on the transient forcal cerebral ischemia in rats. Method : We prepared ischemic rats by the transient middle cerebral artery occlution(MCAO; 90 min occlusion and 144 h reperfusion) in rat brains. BHT-C extract (100 and 200 mg/kg, i.p.) was administered every day after the onset of MCAO until 6 day. Result : BHT-C extract increased survival rate of ischemic rats compared with vehicle-treated rats. BHT-C extract treated rats (100 and 200 mg/kg) were shown a significant reduction in infarct volume compared with vehicle-treated rats. Conclusions : These results suggest that BHT-C extract may contribute to its protective effects in brain ischemia through the reduction of brain infarction.

• Tuberculosis and Respiratory Diseases
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• v.56 no.5
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• pp.532-535
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• 2004

Acute fulminating pulmonary edema was developed in 20 year old female following an acute airway obstruction due to a burglary attack on neck with bare hands. The pathogenesis of pulmonary edema is related to the alveolar and capillary damage induced by the severe negative pressure generated by attempting to inspire against the closed upper airway. This female responded to fluid restriction and oxygen supply. To our knowledge, pulmonary edema caused by man has never been reported in the literature.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.240-240
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• 1994

1. 천연 항염증 물질의 분리 천연 항염증 약물 개발을 목표로 하여 한방과 민간에서 소염, 진통의 목적으로 이용되는 식물들을 대상으로 Carrageenin에 의해 유도된 백서 후족 부종의 억제를 지표로 Screening을 행한 결과, 2종의 식물의 부탄을 엑스가 항염증 활성을 나타내었다. 즉, 호랑가시나무(flex cornuta L. ) 잎 및 쑥부쟁이 (Aster yomena Makinc)의 부탄을 엑스가 Aspirin(300mg/kg)에 필적하는 항염증작용을 나타내었다. 이 식물들의 부탄을 엑스로 부터 각각 2종의 화합물을 분리하였다. 호랑가시나무로 부터는 01eanane type의 monodesmoside와 Pomolic acid bisdesmoside가, 쑥부쟁이로 부터는 Hederagenin bisdesmoside및 구조 미확정의 물질이 각각 분리되었다. 2.천연 항염증 물질의 구조 변환 항염증 약물로 많이 이용되고 있는 시호(Bupleurum falcatum L.)의 유효성분인 Saikosaponin-a의 용해도 개선을 위하여 그 유도체를 합성하였다. 합성된 Saikosaponin-a hemisuccinate의 K염은, 용해도 시험 결과 현저한 용해도 증가를 보였다.

• The Journal of Korean Physical Therapy
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• v.21 no.4
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• pp.103-109
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• 2009

Purpose: Cases of male external genitalia lymphedema are relatively uncommon in the clinical physical therapy field. Of more than two thousand clinical cases treated by the author in the lymphedema treatment center, only 4~5 cases of male external genitalia lymphedema were encountered. The present case report presents the experience and treatment results of male external genitalia lymphedema from urological cancer. Method: This case was a 47-year-old man, who was treated with complex decongestive physical therapy consisting of manual lymph drainage, compression bandage (including the external genitalia), remedial exercise, skin care. Result: The results were relatively good. The clinical experience would suggest that early treatment and education can reduce the external genitalia lymphedema. However, the treatment efficacy remains limited. Therefore, early treatment is vital for more successful outcomes. Conclusion: The relief of symptoms and a decrease in male external genitalia lymphedema may be the best result from long-term conservative management.

• Korean Journal of Veterinary Research
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• v.14 no.2
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• pp.211-214
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• 1974

The authors observed typical skin form of avian staphylocorcosis in 12 day-old-chickens which were kept on the floor. The lesions observed were edematous, necrotic and crusty dermatitis on the wings, the head, the neck and the other parts of the body. Delta hemolytic type Staphylococcus aureus and Herellea were isolated from the lesions of each bird examined.