• Journal of the Society of Cosmetic Scientists of Korea
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• v.36 no.1
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• pp.89-92
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• 2010

In the previous study, we reported the antioxidative activity, antiaging activity, antibacterial activity and moisturizing effect of cream containing Persicaria hydropiper L. extract. In this study, the components of Persicaria hydropiper L. extract were analyzed by TLC and HPLC. Aglycone fractions obtained from the deglycosylation reaction of ethyl acetate fraction among the Persicaria hydropiper L. extract, showed 2 bands and 2 peaks in TLC and HPLC experiments, respectively. Two components were identified as quercetin and kaempferol. TLC chromatogram of ethyl acetate fraction of Persicaria hydropiper L. extract revealed 6 bands and HPLC chromatogram showed 7 peaks, which were identified as quercetin, hyperin, isoquercitrin, quercitrin, kaempferol. In conclusion, with the antioxidative activity, antiaging activity, antibacterial activity and moisturizing effect reported previously, component analysis of Persicaria hydropiper L. extracts could be applicable to new cosmeceuticals.

• Journal of the Korean Applied Science and Technology
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• v.39 no.2
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• pp.303-313
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• 2022

In this study, the extracted oils and commercial oils (Clarisse) were analyzed after GC-MSD fragrance component analysis for each natural essential oil obtained through steam distillation extraction (cypress, seokchangpo, lavender) of a total of three plants grown and grown in Jangheung area. Easy, cinnamon, frankincense) was combined to confirm cytotoxicity, antioxidant, anti-inflammatory, and whitening effects, confirming its potential as a cosmetic material. As a result of the analysis of fragrance components, sabinene was identified as the main component of cypress oil, asarone in seokchangpo oil, and L-Linalool in lavender oil. At a concentration of 100 𝜇L/mL with no cytotoxicity of 6 essential combination oils, NO production was inhibited by 27.76%, DPPH radical scavenging activity was 99.69%, ABTS radical scavenging activity was 94.66%, and tyrosinase inhibitory activity was 55.9%. Possibility of being useful as a raw material for functional cosmetics was presented.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.35 no.4
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• pp.309-315
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• 2009

In our search for the natural cosmetic ingredients, we found that Euryale ferox seed extract exhibited the strong antioxidative activity. Five active compounds were isolated from the ethyl acetate extract through various chromatographic methods and their structures were determined by NMR and MS spectral analysis. These compounds were identified as fucosterol (1), 3-(4-hydroxy-3-methoxybenzyl)-4-[(7'R),5'-dihydroxy-3'-methoxybenzyl]tetrahydrofuran (2), resorcinol (3), pyrogallol (4) and 4-O-methylgallic acid (5).We evaluated the antioxidative, antielastase activities and melanogenesis inhibitory effects of these compounds. The $SC_{50}$ values of compounds 2 ~ 5 for free radical scavenging activity were $17.0\;{\sim}\;100.2\;{\mu}M$ and especially compounds 4 and 5 were 6-fold more effective than ferulic acid as a positive control. And compounds 2 ~ 4 inhibited human neutrophil elastase with $IC_{50}$ values of $18.8\;{\sim}\;78.2\;{\mu}M$ and compound 3 also inhibited melanin synthesis in B16F10 melanoma cells with an $IC_{50}$ value of $492.8\;{\mu}M$. These results suggest that Euryale ferox extract having a lot of various active ingredients may be useful as a natural multi-functioning agent.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.29 no.1
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• pp.27-44
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• 2003

전반적인 피부세포의 생리적 지능 자하로 인한 자연노화와 더불어, 여러 피부 스트레스 요인들이 다양하게 작용하여 발생하는 외인성노화를 방지하거나, 개선할 수 있는 항노화소재로서의 개발 가능성을 알아보기 위해, 예로부터 항염활성이 있다고 알려진 oleanolic acid(OA)를 포함한 ursolic acid(UA), betulin, betulinic acid(BA) 등의 triterpenoids가 어떻게 피부에서의 항노화 활성을 나타내는지를 알아보았다. 시험 결과, OA는 자외선에 의한 각질형성세포에서의 PGE$_2$ 생성과 섬유아세포(NHF)에 의한 matrix metalloproteinase-1(MMP-1) 분비를 억제하였다. 그리고, NHF의 procollagen 생성을 촉진하였으며, 이런 procollagen 생성촉진활성이 in vivo에서도 발현되는 것을 무모생쥐의 실험을 통해서 확인하였다. 또한 OA는 각질세포의 증식과 분화를 촉진하여 표피세포로 하여금 세라마이므와 필라그린 생성을 증가시키도록 하는 작용도 있음을 보여주었다. 더불어 실험한 UA, betulin, BA 들은 비록, betulin, BA의 경우 세포 독성이 다른 물질 들에 비해 높았고, UA가 각질세포의 분화를 오히려 억제하는 양상을 보이기는 했지만, 대부분의 기능은 OA와 유사하였다. 피부세포보호작용과 진피 기질물질에 대한 작용, 그리고, 표피의 장벽기능과 보습기능에 대해 시험한 본 연구는, 식물성분인 triterpenoids가 피부를 위한 항노화소재로서의 개발 가능성이 있음을 확인하는 계기가 되었고, 그 중에서도 OA가 보다 우수한 항노화 소재가 될 수 있음을 시사하고 있다.

• Journal of Digital Convergence
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• v.19 no.4
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• pp.365-371
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• 2021

In order to verify the effect of using functional cosmetic ingredients for skin beauty, the composition and content of some phenolic acid and flavonoids in the hot water and 80% methanol extract of Akebia quinata fruit pericarp and seeds were analyzed, and the skin care antioxidant activity was investigated. The results are as follows. Total polyphenol and flavonoid contents were found to be higher in pericarp extract than seed extract in both hot water and 80% methanol extract. In the analysis of the composition and content of phenolic acid and flavonoids, two kinds of phenolic acids were identified in the hot water extract of pericarp, 6 kinds of phenolic acids were identified in the 80% methanol extract, and one kind of flavonoid. Two types of phenolic acids were identified in the hot water and 80% methanol extract of seeds, respectively. DPPH and ABTS radical scavenging activities tended to increase in proportion to the treatment concentration in both hot water and 80% methanol extracts, and antioxidant activity was found to be high. Therefore, from the above results, it was found that the hot water and 80% methanol extract of Akebia quinata fruit pericarp and seeds contained various kinds of phenolic acid and flavonoids, and the antioxidant activity was also high. It is believed to be of value as a natural antioxidant in skin care cosmetic ingredients.

• Journal of the Korean Applied Science and Technology
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• v.40 no.6
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• pp.1373-1380
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• 2023

This study investigated the effects of coumarin, a flavonoid known for various physiological activities like antiviral, anticancer, and antibacterial properties, on anti-oxidants and anti-inflammatory processes, aiming to explore its application in functional cosmetics. The results are as follows: Cell toxicity experiments using RAW 264.7 cells showed no significant cytotoxicity for coumarin at any concentration, indicating its safety for skin application. Observing coumarin's antioxidant activity through DPPH radical scavenging showed concentration-dependent effectiveness, though not significantly varied with concentration. The inhibition of silica-induced ROS production in cells was concentration-dependent. Both NO production inhibition and histamine release measurements showed concentration-dependent suppression. These findings suggest that Coumarin can be effectively used as a natural ingredient in cosmetic development for its antioxidant and anti-inflammatory properties.

• Journal of Convergence for Information Technology
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• v.10 no.12
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• pp.166-174
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• 2020

Cosmetic functional ingredients are products of emotional convergence technology. Unlike pharmaceuticals, it is very important that cosmetics ingredients contain emotional attractiveness because they are household products that have limitations in their effectiveness. Ginseng has long been used as a major prescription of oriental medicine for human health. Detailed records such as the origin and propagation of ginseng can lead to various cosmetical application of ginseng as an emotional convergence ingredients that utilizes the authenticity and excellence of ginseng as an asset of K-beauty. In the unfortunate reality that the first records of ginseng use depend on ancient Chinese literature, it is very meaningful to describe and leave the records of ginseng used in the field of beauty. This study examined the general historical records needed for the study of the cosmetics application of ginseng and the recent findings of ginsenoside in the area of skin function, and provided basic data that can be applied to new cosmetics development research.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.3 s.47
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• pp.329-343
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• 2004

Recently, our society has prominently raised the desire to well-being life since not only our economical situations are better than before, but environmental pollution become serious. In well-being trends, the natural or nature-related products are also issued on their usages as bio-/raw materials for our living industries, such as cosmetics, household goods, and so on. Especially, various materials which comes from medicinal plants has been discovered their physiological properties and validated their functions. Thus, they have been subjected to several processes, including extraction, isolation and concentration, and popularly introduced to cosmetic industry. In these reasons, a variety of cosmetic Products using natural materials has been developed, which are focused on whitening, wrinkle improvement, and anti-aging. In this report, we present a brief review of the function and classification of natural products interested in until now, and introduce the natural materials for cosmetics having physiological activities on skin, including Fructan, Acrea extract, Portulaca extract, Licorce extract, Dandelion extract, Ulmus extract, SC-glucan, Arbutin, and Sophora extract.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.1
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• pp.11-18
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• 2017

An anti-aging compound ethyl (4-(2,3-dihydro-1H-indene-5-carboxyamido) benzoate) rapidly crystallizes in emulsion systems, and a flavonoid 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone bearing a whitening function causes coloration of cosmetic compounds when mixed with metal oxides. In this study, an electrospray method was used to encapsulate water-insoluble bioactive compounds in polymeric microparticles. Poly (methyl methacrylate) and polycaprolactone were used to encapsulate ethyl (4-(2,3-dihydro-1H-indene-5-carboxyamido) benzoate) and 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone, respectively. It was found that polymer concentration, the structure of electrospray nozzle, and compatibility between polymers and bioactive compounds were important factors in the preparation of the particles. Polycaprolactone particles encapsulating 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone was effective in preventing coloration of a cosmetic compound when mixed with metal oxides.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.3
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• pp.229-235
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• 2015

Skin aging is the phenomena finally expressed on the skin surface and related to the changes in the microstructure of the skin texture. Which is resulted in wrinkle formation and uneven tone of skin and so on. In this study, the synergy effect of Cedrol and a collagen-derived peptide in type III collagen synthesis was evaluated by in vitro test. The physiological skin state of 22 female volunteers was measured after using the cosmetics for 4 weeks. Results showed that Cedrol and a collagen-derived peptide had the excellent synergy effect in type III collagen synthesis. The cosmetics improved skin microrelief, star configurations, skin gloss, skin tone, hydration and elasticity except skin lightening. In conclusion, this study proved that Cedrol and collagen-derived peptide had the synergy effect of type III collagen synthesis in the cell level and cosmetics with those was improved skin aging in human volunteer test.