• Title/Summary/Keyword: 근감소

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Effect of Combined Exercise on Fall Injury Index and Myokine in Older Adults (복합운동이 노인여성의 낙상관련지표 및 Myokine에 미치는 효과)

  • Park, Woo-Young
    • Journal of the Korean Applied Science and Technology
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    • v.36 no.1
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    • pp.189-199
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    • 2019
  • The aim of this study was to investigate the effect of combine exercise on the fall injury related index and myokine in elderly women. Sarcopenia leads to a loss of strength, alter on to a decreased functional status, impaired mobility, a higher risk of falls, and eventually an increased risk of mortality. Aerobic exercise characterized by rhythmic and repetitive movements of large muscles, for sustained periods that depends primarily on the use of oxygen to meet energy demands through aerobic metabolism, and that is structured and intended to generate improvements in cardiopulmonary fitness, body composition, and cardiorespiratory health. Resistance training has performance in the elderly. As combined exercise therapy can be used to enhance muscle functions and cardiopulmonary functions, it is being highlighted as an effective health management methods for the aged. The myokine has been regarded an important factor of exercise how muscle communicate adipose tissue, bone and muscle to exert beneficial effects at the whole body level.

Effect of Pu'er tea extract on C2C12 myoblast differentiation (보이차 열수 추출물의 근아세포 근분화에 미치는 영향)

  • Lee, Hyoseong;Choi, Sunkyung;Lee, Boyeong;Kim, Eunmi;Lee, Woonghee;Han, Hyosang;Kim, Keekwang
    • Journal of Digital Convergence
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    • v.18 no.12
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    • pp.585-594
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    • 2020
  • At present, aging-related degenerative muscle diseases are considered a serious problem. However, the drug effect on the treatment and prevention of sarcopenia has not been investigated. The purpose of this study was to evaluate the value of extract of Pu'er tea as a remedy to alleviate the symptoms of sarcopenia. Pu'er tea extracts showed excellent radical scavenging ability. The expression of Myh3 was promoted and myotube formation also was increased by treatment of Pu'er tea extracts. These results suggest that Pu'er tea is a natural substance that promotes myogenesis, and is valuable as a material for pharmaceutical research on the prevention and treatment of various muscle diseases, including sarcopenia. And It is necessary to confirm specific indicator substances of puer tea and further study on this.

Bond Characteristic Between Lightweight Concrete and GFRP Bar (경량콘크리트와 GFRP 보강근의 부착 특성)

  • Son, Byung-Lak;Kim, Myung-Sik;Kim, Chung-Ho;Jang, Heui-Suk
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.17 no.6
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    • pp.112-121
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    • 2013
  • FRP reinforced lightweight concrete structures can offer corrosion resistance and weight reduction effect simultaneously, so practical use of the structures may be expected afterwards. But to make concrete structures using lightweight concrete and FRP bar, that can resist external forces without internal slip of the FRP bar, it is very important to understand bond characteristic between lightweight concrete and FRP bar. During that time, a lot of studies for bond behaviors of FRP bar in normal concrete were conducted, but studies for bond behavior of FRP bar in lightweight concrete are very limited to date. So, bond characteristic between lightweight concrete and helically deformed GFRP bar was investigated in this study. Three main parameters were considered in experimental investigation: type of rebar, concrete type, and compressive strength of lightweight concrete. As an experimental result, it could be known that bond strength of helically deformed GFRP bar in lightweight concrete was 0.49 times bond strength of steel reinforcement in normal concrete.

Effects of Scapular Dynamic Stabilization Exercise Applying EMG Biofeedback on Upper Trapezius, Pectoralis Major and Serratus Anterior Activities (근전도 바이오피드백을 적용한 어깨뼈 동적 안정화운동이 위등세모근, 큰가슴근 및 앞톱니근 활성에 미치는 영향)

  • Yun, Sam-Won;Kang, Jong-Ho
    • Journal of Convergence for Information Technology
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    • v.7 no.4
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    • pp.159-164
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    • 2017
  • The aim of this study was to investigate the effects of scapular dynamic stabilization exercise(SDex) with electromyography(EMG) biofeedback on the upper trapezius(UT), pectoralis major(PM) and serratus anterior(SA) activities. Fifteen healthy male voluntarily participated in this study. A paired t-test was used for statistical analysis. The study showed, through EMG biofeedback, that EMG activity significantly decreased in the UT, PM and increased in the SA(P<0.05). These results suggest that SDex with EMG biofeedback is effective to selectively strengthen the SA. This article is meaningful in that it is the first article using SDex with EMG biofeedback.

Inhibition of SKTI Synthesis in Agrobacterium rhizogenes-induced Hairy Root Reduces the Number of Nodule in Soybean (Kunitz Trypsin Inhibitor 발현 억제에 의한 콩 뿌리혹 수의 감소)

  • Kim, Sun-Hyung;Lim, Chae-Woo;Park, Ji-Young;Hwang, Cheol-Ho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.54 no.3
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    • pp.299-306
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    • 2009
  • In nitrogen-limited conditions, rhizobia lead to formation of nitrogen-fixing nodules on the roots of leguminous plants. The process of nodulation is autoregulated by pre-existing nodules in the same root system. The altered profile of sap proteins by inoculation with B. japonicum may indicate presence of a signal responsible for autoregulation transferred through stem. The 20 kDa protein enhanced by innoculation significantly decreased in intensity from 2.5 to 7 days after inoculation (DAI). However 6 kDa protein did increase during such a transition period. Western blot analysis showed that both 20 kDa and 6 kDa were cross-reacted with the SKTI antiserum. This suggests that SKTI may be involved in soybean nodulation by specific induction and degradation in stem sap during early stage of nodulation. RNAi technique and Agrobacterium rhizogenes-mediated transformation were applied to investigate the function of SKTI in nodulation. We have found that the number of rhizobium-induced nodule was much less in SKTIi-silenced hairy roots than the non-silenced. Indeed the quantitative RT-PCR showed that the expression level of SKTI gene was reduced over 40% in the transgenic hairy roots compared to the non-transgenic. It appears that the observed early induction of SKTI and degradation into small peptide in a specific time manner may be involved in autoregulation of nodulation in soybean and the specific mechanism of such regulation remains to be investigated.

Effects of maternal exercise on expression of GLUT-4, VAMP-2 in skeletal muscle and plasma insulin and leptin levels in pregnant rats (운동이 F344계 임신쥐에서 골격근의 VAMP-2 및 GLUT-4 단백질 발현과 혈중 인슐린, 렙틴 농도에 미치는 영향)

  • Yoon, Jin-Hwan;Lee, Hee-Hyuk;Kim, Jong-Oh;Oh, Myung-Jin;Park, Seong-Tae;Jee, Young-Seok;Seo, Tae-Beom;NamGung, Uk
    • Journal of Life Science
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    • v.17 no.6 s.86
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    • pp.859-866
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    • 2007
  • The main objective of this study was to investigate the effects of exercise on serum insulin and leptin levels and GLUT-4 and VAMP-2 in skeletal muscles from the pregnant rats. F344 rats were randomly divided into four groups (n = 15 in each group): control group (CG), pregnant group (PG), pregnant running group (PR), and pregnant swimming group (PS). From the 15th day of pregnancy, animals in the running group were forced to run on treadmill for 30 min with a light intensity, while those in the swimming group were forced to swim in swimming pool for 10 min once a day for 6 consecutive days. The present result demonstrated that in pregnant rat group, serum insulin levels significantly in-creased and leptin levels significantly decreased. Skeletal GLUT-4 and VAMP-2 protein expression was significantly decreased in pregnant rats compared to non-pregnant rats. However, matenal running during gestational period alleviated pregnancy-induced changes in plasma insulin and leptin levels, and it significantly enhanced skeletal GLUT-4 and VAMP-2 protein expression. From those results, it can be suggested that running exercise during gestational period may improve glycemic control by up-regulating GLUT-4 and VAMP-2 protein expression.

Correlation Between Pectoralis Minor, Shoulder Mobility and Neck Range of Motion on Rounded Shoulder Posture for Life-Care Increase in Women University Student (여대생의 라이프 케어 증진을 위한 둥근 어깨 자세의 작은가슴근, 어깨가동성과 목 관절가동범위의 상관연구)

  • Seo, Tae-Hwa;Kim, Min-Sun;Jeong, Yeon-Woo
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.5
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    • pp.239-246
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    • 2019
  • This study aims to examine the correlation between pectoralis minor, shoulder mobility, and neck range of motion on rounded shoulder posture for Life-care increase in Women university student. The 80 female adults with rounded shoulder posture were selected for this study. Measurements of shoulder height were obtained by measuring the rounded shoulder posture using a caliper. To measure the length of pectoralis minor, a tape measure was used to measure from the point where the 4th rib and sternum meets to the inferior medial side of coracoid process. Shoulder mobility was measured by holding fists in both hands, then raising one side of the elbow until the palm on that side can be placed on the back, while lowering the other side of the elbow until the back of the hand on that side can be placed on the back. Neck range of motion was used to measure the neck movement including the flexion and the extension, lateral flexion to the right or to the left, and rotation to the right or to the left. The results of this study showed that there are significant negative correlations between pectoralis minor index, shoulder mobility, and neck range of motion in rounded shoulder posture(p<0.05). From these results, in female students with rounded shoulder, the lateral flexion of the neck to the left decreased as the left shoulder mobility increased, the neck extension decreased as the right pectoralis minor shortened, and the rotation of the neck to the left decreased as the left shoulder mobility increased.

Experimental Study for Shear Strength of Fiber-Reinforced-Polymer Reinforced Concrete Beams (GFRP 보강근 콘크리트 보의 전단성능에 대한 실험적 고찰)

  • Park, Jong-Sup;Park, Young-Hwan;You, Young-Jun
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.57-60
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    • 2008
  • Compared with a steel-reinforced section with equal areas of longitudinal reinforcement, a cross section using FRP flexural reinforcement after cracking has a smaller depth to the neutral axis because of the lower axial stiffness. The compression region of the cross section is reduced, and the crack widths are wider. As a result, the shear resistance provided by both aggregate interlock and compressed concrete is smaller. Research on the shear capacity of flexural members without shear reinforcement has indicated that the concrete shear strength is influenced by the stiffness of the flexural reinforcement. In this research, experimental observations were made for the shear strength of FRP reinforced concrete beam and validity of existing predicting equations were examined. Test results showed that shear strength decreased as shear-span increased.

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The role of myokine(interleukin) and exercise for the prevention of scarcopenia and anti-inflammation (근감소 및 염증 예방을 위한 운동과 인터루킨(IL-interleukin)의 역할)

  • Byun, Yong-Hyun;Park, Woo-Young
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.2
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    • pp.509-518
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    • 2018
  • The purpose of this study was myokine product and role with physical activity and literature review. There is accumulating epidemiological evidence that a physically active life plays an independent role in the protection against type 2 diabetes, cardiovascular disease, colon cancer, dementia and even depression. And myokine has been regarded an important factor of exercise training and brain growth factor for the prevention of Alzheimier's disease. During exercise the release of anti-inflammatory myokine from contracting muscle controled the metabolic response, and IL-4, IL-6, IL-7, IL-10, and IL-15 controled muscle hypertrophy, myogenesis and angiogenenesis. IL-6 promoted the lipid metabolism through AMPK activation. IL-1Ra, IL-10 and sTNF-R inhibited $TNF-{\alpha}$ as the pro-inflammatory cytokine. IL-15 increased the releasing volume from contracting muscle, and promoted the anabolic factor of muscle growth. IL-7 and IL-8 activated the angiogenesis through the more activation of C-X-C receptor signal transmission.

근골격계 질환 예방을 위한 시스템적 접근과 추진전략

  • 정은교
    • Bulletin of the Korean Institute for Industrial Safety
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    • v.3 no.1
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    • pp.18-24
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    • 2003
  • 최근 산업사회의 급속한 환경변화는 근로자의 상병구조에서도 나타나 작업이 단순반복화 되며 다양한 작업공구를 반복적으로 사용하게 되어 작업속도와 작업량이 많아지고 운동부족으로 인한 근력의 약화 등에 의해서 근골격계질환이 급속히 증가하고 있다. 이로 인한 근로자의 삶의 질은 물론 결근에 의한 노동력 손실, 제품불량 증가, 산재보상비용 지출증가 등으로 성장을 둔화시키고 사회$.$경제적으로 문제의 심각성을 더해주고 있다. 최근 노동부가 발표한 산업재해통계를 보면 2002년도 산업재해 중 업무상질병자는 5,417명으로 전년대비 136명 감소하였으나, 이중 직업성 근골격계질 환자(신체부담작업 및 요통)는 1,827명으로 전년대비 193명(11.8%) 증가한 것으로 나타났고, 그 발생양상이 집단적이라는 특성을 갖고 있다. 이처럼 직업성 근골격계질환의 업무상 질병에서 차지하는 비율이 증가추세에 있고 대부분의 선진국에서도 과거에는 각종 화학물질에 의한 직업병이 상위를 차지해 오다가 근래에는 동 질환이 업무상질병의 상당부분 이상으로 차지하고 있다. 미국의 경우 1998년 한해동안 253,300건(64.2%) 발생하였고 이 가운데 자동차 관련업종이 가장 많은 비율을 점유하고 있다.(중략)

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