• Title/Summary/Keyword: 구현단계

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A Study on the Automation and Optimization of 9-(4-[$^{18}F$] Fluoro-3-hydroxymethylbutyl) Guanine Synthesis (9-(4-[$^{18}F$] Fluoro-3-hydroxymethylbutyl) guanine 합성의 자동화와 최적화에 관한 연구)

  • An, Jae-Seok;Hong, Sung-Tack;Kang, Se-Hun;Won, Woo-Jae
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.2
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    • pp.72-75
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    • 2011
  • Purpose: The HSV1-tk reporter gene system is the most widely used system because of its advantage is that it is possible to monitor directly without the introduction of a separate reporter gene in case of HSV1-tk suicide gene therapy. This study was performed to automate 9-(4-[$^{18}F$] Fluoro-3-hydroxymethylbutyl) guanine ([$^{18}F$] FHBG) that are widely used as substrate for the HSV1-tk reporter gene in living organisms with positron emission tomography (PET) and find the optimized conditions of synthesis. Materials and Methods: Fully automated synthesis of [$^{18}F$] FHBG was performed using Explora-RN (CTI, USA) module. We have changed of reaction time (3, 5, 10 min) and temperature (110, 120, $130^{\circ}C$) for the optimized conditions of synthesis. Also we experimented to find the optimal concentration of precursor (5, 7, 10 mg). Results: [$^{18}F$] FHBG was purified by HPLC system and collected at around 10-12 min. Synthesis using Explora-RN module showed a $32.0{\pm}1.2%$ yield of radiochemical (decay corrected), the purity was greater than 98%. And the entire synthesis time was less than 48 min. Temperature of the highest synthesis yield was $130^{\circ}C$, reaction time was 5 minutes and concentration of precursor was 10 mg (recommended volume in manual) (n=36). In contrast to radiochemical yield of precursor 10 mg ($32{\pm}1.2%$), yield of 5 and 7 mg precursor was unstable. Conclusion: Automation of [$^{18}F$] FHBG synthesis at Explora-RN module has been completed. In addition, we were able to obtain optimized reaction time, temperature and concentration of precursor. Therefore this study would be provided more rapid synthesis and higher radiochemical yield.

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Insecticidal Activity and Effect on Biological Characteristic of 16 Insecticides Against Phthorimaea Operculella (Lepidoptera: Gelechiidae) (감자뿔나방에 대한 16종 살충제의 살충활성과 생물적 특성에 미치는 영향)

  • An, Jeong-Jin;Park, Jun-Won;Kim, Ju-Il;Kim, Hyun Kyung;Koo, Hyun-Na;Kim, Gil-Hah
    • The Korean Journal of Pesticide Science
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    • v.17 no.4
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    • pp.363-370
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    • 2013
  • Susceptibility of each developmental stage of Phthorimaea operculella (Lepidoptera: Gelechiidae) were investigated using 16 insecticides which are available in the market in Korea. For the eggs and pupae, only spinosad showed a 71.1% inhibition rate for egg hatchability and a 66.7% inhibition rate for emergence. For the 3rd instar larvae, the feeding toxicities were over 90% for fenitrothion ($LC_{50}$ 336.6 ppm), esfenvalerate ($LC_{50}$ 8.6 ppm), ethofenprox ($LC_{50}$ 35.7 ppm), and emamectin benzoate ($LC_{50}$ 0.05 ppm). Furthermore, the contact toxicities were over 90% for esfenvalerate ($LC_{50}$ 0.87 ppm), ethofenprox ($LC_{50}$ 16.5 ppm), emamectin benzoate ($LC_{50}$ 0.53 ppm), and spinosad ($LC_{50}$ 2.48 ppm) at the recommended concentrations. Deltamethrin and spinosad yielded 100% mortality for adult P. operculella 48 h after treatment. The adult female fecundity was inhibited by deltamethrin, esfenvalerate, emamectin benzoate, spinosad and dinotefuran, which were significantly different from the control. The adult longevities (7.3-8.3 days) were reduced by approximately 1-2 days compared with the control (9.3 day). The emamectin benzoate maintained 100% insecticidal activity 14 days after treatment and ethofenprox maintained over 90% activity 7 days after treatment.

Definition and Division in Intelligent Service Facility for Integrating Management (지능화시설의 통합운영관리를 위한 정의 및 구분에 관한 연구)

  • PARK, Jeong-Woo;YIM, Du-Hyun;NAM, Kwang-Woo;KIM, Jin-Young
    • Journal of the Korean Association of Geographic Information Studies
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    • v.19 no.4
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    • pp.52-62
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    • 2016
  • Smart City is urban development for complex problem solving that provides convenience and safety for citizens, and it is a blueprint for future cities. In 2008, the Korean government defined the construction, management, and government support of U-Cities in the legislation, Act on the Construction, Etc. of Ubiquitous Cities (Ubiquitous City Act), which included definitions of terms used in the act. In addition, the Minister of Land, Infrastructure and Transport has established a "ubiquitous city master plan" considering this legislation. The concept of U-Cities is complex, due to the mix of informatization and urban planning. Because of this complexity, the foundation of relevant regulations is inadequate, which is impeding the establishment and implementation of practical plans. Smart City intelligent service facilities are not easy to define and classify, because technology is rapidly changing and includes various devices for gathering and expressing information. The purpose of this study is to complement the legal definition of the intelligent service facility, which is necessary for integrated management and operation. The related laws and regulations on U-City were analyzed using text-mining techniques to identify insufficient legal definitions of intelligent service facilities. Using data gathered from interviews with officials responsible for constructing U-Cities, this study identified problems generated by implementing intelligent service facilities at the field level. This strategy should contribute to improved efficiency management, the foundation for building integrated utilization between departments. Efficiencies include providing a clear concept for establishing five-year renewable plans for U-Cities.

A Study on the Application of RTLS Technology for the Automation of Spray-Applied Fire Resistive Covering Work (뿜칠내화피복 작업 자동화시스템을 위한 RTLS 기술 적용에 관한 연구)

  • Kim, Kyoon-Tai
    • Journal of the Korea Institute of Building Construction
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    • v.9 no.5
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    • pp.79-86
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    • 2009
  • In a steel structure, spray-applied fire resistive materials are crucial in preventing structural strength from being weakened in the event of a fire. The quality control of such materials, however, is difficult for manual workers, who can frequently be in short supply. These skilled workers are also very likely to be exposed to environmental hazards. Problems with construction work such as this, which are specifically the difficulty of achieving quality control and the dangerous nature of the work itself, can be solved to some degree by the introduction of automated equipment. It is, however, very difficult to automate the work process, from operation to the selection of a location for the equipment, as the environment of a construction site has not yet been structured to accommodate automation. This is a fundamental study on the possibility of the automation of spray-applied fire resistive coating work. In this study, the linkability of the cutting-edge RTLS to an automation system is reviewed, and a scenario for the automation of spray-applied fire resistive coating work and system composition is presented. The system suggested in this study is still in a conceptual stage, and as such, there are many restrictions still to be resolved. Despite this fact, automation is expected to have good effectiveness in terms of preventing fire from spreading by maintaining a certain level of strength at a high temperature when a fire occurs, as it maintains the thickness of the fire-resistive coating at a specified level, and secures the integrity of the coating with the steel structure, thereby enhancing the fire-resistive performance. It also expected that if future research is conducted in this area in relation to a cutting-edge monitoring TRS, such as the ubiquitous sensor network (USN) and/or building information model (BIM), it will contribute to raising the level of construction automation in Korea, reducing costs through the systematic and efficient management of construction resources, shortening construction periods, and implementing more precise construction

Marine Geophysical Constraints on the Origin and Evolution of Ulleung Basin and the Seamounts in the East Sea (울릉분지와 동해 해산의 기원과 발달과정에 대한 해양지구물리학적 연구)

  • Kim Jinho;Park Soo-chul;Kang Moo-hee;Kim Kyong-O;Han Hyun-chul
    • Economic and Environmental Geology
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    • v.38 no.6 s.175
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    • pp.643-656
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    • 2005
  • The East Sea, a marginal sea or back-arc basin, consists of Japan Basin, Yamato Basin, and Ulleung Basin and is surrounded by the Pacific Plate and Philippine Sea Plate. Ulleung Basin locates in the southwestern part of the East Sea and shows the depth of 1,500 m in average and 2,500 m in maximum, connecting to the Japan Basin along 2,000 m contour. The slope of the seafloor is greater in the western side of the basin than in the southern and the eastern side. The crustal thickness of the Ulleung Basin from the OBS tends to get thicker toward the north and the west side and the sediment thickness of the Ulleung Basin is getting thicker toward the southeast side and reaches up to 12 km. The crustal type of the Ulleung Basin was variously suggested as like as a rifted continental crust, an extended continental crust, and an incipient oceanic trust. The origin of the crustal formation and the Ulleung Basin, however, is still controversial. Based on the bathymetry and gravtiy anomaly data for this study, the axis of the Ulleung Basin shows that the basin develops along the axis trending NW-SE direction and reveals a general symmetry of the bathymetry. And also the free-air gravity anomalies show a very similar pattern to the bathymetry of the basin. The sediment thickness is relatively thicker in the southeastern side of the basin than in the northwestern side. Although the crustal age of the Ulleung Basin is supposed to be younger than them of the Japan Basin and the Yamato Basin, the free-air gravity anomalies of the Ulleung Basin ranging -40 to 50 mGals are lower than the other basins, which suggests that the densities of crust and sediment of the Ulleng Basin are lower than the Japan Basin and the Yamato Basin.

Investigation of the Signal Characteristics of a Small Gamma Camera System Using NaI(Tl)-Position Sensitive Photomultiplier Tube (NaI(Tl) 섬광결정과 위치민감형 광전자증배관을 이용한 소형 감마카메라의 신호 특성 고찰)

  • Choi, Yong;Kim, Jong-Ho;Kim, Joon-Young;Im, Ki-Chun;Kim, Sang-Eun;Choe, Yearn-Seong;Lee, Kyung-Han;Joo, Koan-Sik;Kim, Byung-Tae
    • The Korean Journal of Nuclear Medicine
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    • v.34 no.1
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    • pp.82-93
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    • 2000
  • Purpose: We characterized the signals obtained from the components of a small gamma camera using Nal(Tl)-position sensitive photomultiplier tube (PSPMT) and optimized the parameters employed in the modules of the system. Materials and Methods: The small gamma camera system consists of a Nal(Tl) crystal ($60{\times}60{\times}6mm^3$) coupled with a Hamamatsu R3941 PSPMT, a resister chain circuit, preamplifiers, nuclear instrument modules (NIMs), an analog to digital converter and a personal computer for control and display. The PSPMT was read out using a resistive charge division circuit which multiplexes the 34 cross wire anode channels into 4 signals (X+, X-, Y+, Y -). Those signals were individually amplified by four preamplifiers and then, shaped and amplified by amplifiers. The signals were discriminated and digitized via triggering signal and used to localize the position of an event by applying the Anger logic. The gamma camera control and image display was performed by a program implemented using a graphic software. Results: The characteristics of signal and the parameters employed in each module of the system were presented. The intrinsic sensitivity of the system was approximately $8{\times}10^3$ counts/sec/${\mu}Ci$. The intrinsic energy resolution of the system was 18% FWHM at 140 keV. The spatial resolution obtained using a line-slit mask and $^{99m}Tc$ point source were, respectively, 2.2 and 2.3 mm FWHM in X and Y directions. Breast phantom containing $2{\sim}7mm$ diameter spheres was successfully imaged with a parallel hole collimator. The image displayed accurate size and activity distribution over the imaging field of view Conclusion: We proposed a simple method for development of a small gamma camera and presented the characteristics of the signals from the system and the optimized parameters used in the modules of the small gamma camera.

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A study on the Standardization of Design Guidelines for Geographic Information Databases (지리정보 DB 설계 지침의 표준화 연구)

  • Lim, Duk-Sung;Moon, Sang-Ho;Si, Jong-Ik;Hong, Bong-Hee
    • Journal of Korea Spatial Information System Society
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    • v.5 no.1 s.9
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    • pp.49-63
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    • 2003
  • Recently, two international standard organizations, ISO and OGC, have done the work of standardization for GIS. Current standardization work for providing interoperability among GIS DB focuses on the design of open interfaces. But, this work has not considered procedures and methods for designing GIS DB. Eventually, GIS DB has its own model. When we share the data by open interface among heterogeneous GIS DB, differences between models result in the loss of information. Our aim in this paper is to revise the design guidelines for geographic information databases in order to make consistent spatial data models, logical structures, and semantic structure of populated geographical databases. In details, we propose standard guidelines which convert ISO abstract schema into relation model, object-relation model, object-centered model, and geometry-centered model. Furthermore, we provide sample models for applying these guidelines in commercial GIS S/Ws. Building GIS DB based on design guidelines proposed in the paper has the following advantages: the interoperability among databases, the standardization of schema definitions, and the catalogue of GIS databases through.

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A Study on the Method of Minimizing the Bit-Rate Overhead of H.264 Video when Encrypting the Region of Interest (관심영역 암호화 시 발생하는 H.264 영상의 비트레이트 오버헤드 최소화 방법 연구)

  • Son, Dongyeol;Kim, Jimin;Ji, Cheongmin;Kim, Kangseok;Kim, Kihyung;Hong, Manpyo
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.28 no.2
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    • pp.311-326
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    • 2018
  • This paper has experimented using News sample video with QCIF ($176{\times}144$) resolution in JM v10.2 code of H.264/AVC-MPEG. The region of interest (ROI) to be encrypted occurred the drift by unnecessarily referring to each frame continuously in accordance with the characteristics of the motion prediction and compensation of the H.264 standard. In order to mitigate the drift, the latest related research method of re-inserting encrypted I-picture into a certain period leads to an increase in the amount of additional computation that becomes the factor increasing the bit-rate overhead of the entire video. Therefore, the reference search range of the block and the frame in the ROI to be encrypted is restricted in the motion prediction and compensation for each frame, and the reference search range in the non-ROI not to be encrypted is not restricted to maintain the normal encoding efficiency. In this way, after encoding the video with restricted reference search range, this article proposes a method of RC4 bit-stream encryption for the ROI such as the face to be able to identify in order to protect personal information in the video. Also, it is compared and analyzed the experimental results after implementing the unencrypted original video, the latest related research method, and the proposed method in the condition of the same environment. In contrast to the latest related research method, the bit-rate overhead of the proposed method is 2.35% higher than that of the original video and 14.93% lower than that of the latest related method, while mitigating temporal drift through the proposed method. These improved results have verified by experiments of this study.

Preparation of EVA/Intumescent/Nano-Clay Composite with Flame Retardant Properties and Cross Laminated Timber (CLT) Application Technology (난연특성을 가지는 EVA/Intumescent/나노클레이 복합재료 제조 및 교호집성재(Cross Laminated Timber) 적용 기술)

  • Choi, Yo-Seok;Park, Ji-Won;Lee, Jung-Hun;Shin, Jae-Ho;Jang, Seong-Wook;Kim, Hyun-Joong
    • Journal of the Korean Wood Science and Technology
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    • v.46 no.1
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    • pp.73-84
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    • 2018
  • Recently, the importance of flame retardation treatment technology has been emphasized due to the increase in urban fire accidents and fire damage incidents caused by building exterior materials. Particularly, in the utilization of wood-based building materials, the flame retarding treatment technology is more importantly evaluated. An Intumescent system is one of the non-halogen flame retardant treatment technologies and is a system that realizes flame retardancy through foaming and carbonization layer formation. To apply the Intumescent system, composite material was prepared by using Ethylene vinyl acetate (EVA) as a matrix. To enhance the flame retardant properties of the Intumescent system, a nano-clay was applied together. Composite materials with Intumescent system and nano - clay technology were processed into sheet - like test specimens, and then a new structure of cross laminated timber with improved flame retardant properties was fabricated. In the evaluation of combustion characteristics of composite materials using Intumescent system, it was confirmed that the maximum heat emission was reduced efficiently. Depending on the structure attached to the surface, the CLT had two stages of combustion. Also, it was confirmed that the maximum calorific value decreased significantly during the deep burning process. These characteristics are expected to have a delayed combustion diffusion effect in the combustion process of CLT. In order to improve the performance, the flame retardation treatment technique for the surface veneer and the optimization technique of the application of the composite material are required. It is expected that it will be possible to develop a CLT structure with improved fire characteristics.

The Analyses of Geographers지 Roles and Demands in Korean GIS Industries (GIS 산업에 있어서 지리학의 역할 및 수요에 대한 분석)

  • Chang Eun-mi
    • Journal of the Korean Geographical Society
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    • v.39 no.4
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    • pp.643-664
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    • 2004
  • This study aims to review what geographers have contributed to GIS industries and national needs. To-be-geographers and geographers are expected to meet the gap between what we have teamed in school and what we have to do after graduation. The characteristics of GIS industry in the 1990 are summarized with approximate evaluation of the contribution of geographers in each stage. Author introduced the requirement for the licenses of geomatics and geospatial engineering experts and the other licenses, which are important to get a job in GIS industry from 2003 to 2004. A set of questionnaire on the user's requirements was given to GIS people in private companies and public GIS research centers and analyzed. Author found that they put an emphasis on hands-on experiences and programming skills. no advantages or geography such as capability or integration and inter-disciplinary collaboration were not appreciated. The prospects for the GIS tend to be positive but the reflectance of the prospect was not accompanied by at the same degree of preference for geography. Most government strategies for the next ten years' GIS focus on new-growth leading industries. SWOT(strength, weakness, opportunity, threat) analysis of geography for GIS industry will give some directions such as telematics, regional marketing strategies with web-based GIS technology, location based service. That means intra-disciplinary study in geography will evoke the potentiality of GIS, compared with interdisciplinary studies.