• Journal of Dental Rehabilitation and Applied Science
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• v.38 no.3
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• pp.150-161
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• 2022

Purpose: To determine the effects of the microgroove-fibronectin complex surface on the expression of various genes related to cellular activity in human gingival fibroblasts. Materials and Methods: Smooth titanium specimens (NE0), acid-treated titanium specimens (E0), microgroove and acid-treated titanium specimens (E60/10), fibronectin-fixed smooth titanium specimens (NE0FN), acid-treated and fibronectin-immobilized titanium specimens (E0FN), and microgroove and acid-treated titanium specimens immobilized with fibronectin (E60/10FN) were prepared. Real-time polymerase chain reaction experiments were conducted on 44 genes related to cell behavior of human gingival fibroblasts. Results: Adhesion and proliferation of human gingival fibroblast on microgroove-fibronectin complex titanium were activated through four types of signaling pathway. Integrin α5, Integrin β1, Integrin β3, Talin-2, which belong to the focal adhesion pathway, AKT1, AKT2, NF-κB, which belong to the PI3K-AKT signaling pathway, MEK2, ERK1, ERK2, which belong to the MAPK signaling pathway, and Cyclin D1, CDK4, CDK6 genes belonging to the cell cycle signaling pathway were upregulated on the microgroove-fibronectin complex titanium surface (E60/10FN). Conclusion: The microgroove-fibronectin complex titanium surface can up-regulate various genes involved in cell behavior.

• Journal of the korean academy of Pediatric Dentistry
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• v.50 no.3
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• pp.318-333
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• 2023

The purpose of this study is to analyze changes in dental trauma in children under the age of 12 during the period of Coronavirus Disease 2019 (COVID-19). March 2020, when COVID-19 was officially declared a pandemic by the World Health Organization, was set as the starting point for COVID-19. From March 2018 to February 2020, subjects in the pre-COVID-19 period were classified as the Pre-COVID-19 group, and from March 2020 to March 2022, subjects in the post-COVID-19 period were classified as the COVID-19 group. Information related to trauma was collected through electronic medical records. The number of trauma patients before and after the outbreak of COVID-19 decreased significantly. During the COVID-19 period, there was no significant difference in the male-female ratio or the distribution order of age groups. In the COVID-19 group of permanent teeth, the ratio of trauma caused by personal mobility was higher than trauma caused by sports. In the COVID-19 group of permanent teeth, the ratio of crown fracture with pulp involvement was significantly higher than the ratio of crown fracture without pulp involvement. Changes in trauma patterns caused by COVID-19 were observed more clearly in school-aged children than in preschool children. In a pandemic situation such as COVID-19, it is expected to be used as a good educational basis for knowing that frequent diagnoses can change due to changes in the environment.

• The Journal of KAIRB
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• v.2 no.1
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• pp.23-31
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• 2020

Purpose: To obtain opinions from Korean Institutional Review Board (IRB) members' self-evaluation on ability to conduct fairness review of clinical trial protocol with presence of conflict of interest and from investigators and IRB members on financial conflict of interest through surveying. Methods: IRB members and researchers in 9 different hospitals were asked to answer survey questions via email. Results: Responders were 115 personnel (IRB Chair/vice 18, medical member 30, non-medical member 28, and researcher 39) from 9 centers. Compared to IRB medical members, IRB chair/vice respondents scored higher with statistically significance on 10 point scale (8.44±1.381 vs. 7.30±1.685, p=0.005) when asked to self-evaluate fairness reviewing a protocol proposed by an investigator from the same department and a protocol from the company that supports the scientific committee of responders. When reviewing a protocol proposed by a hospital director, non-medical members scored statistically significantly higher than medical-members (7.47±1.76 vs. 8.07±2.70, p=0.034). When asked about the limitation of labor fee for principal investigator on phase 3 Human clinical trials of the Investigational new drug, while the responses range was wide, 60% answered that labor cost of principal investigator should be less than 30% of total budget for clinical trials with a budget of 100 million won. 51.3% answered that there is no need to disclose the labor cost of the principal investigator in the consent form. Since every investigator can be influenced unconsciously by conflict of interest, the answer that 'responder agrees that there is need for management' was the most chosen answer (IRB member 61.8%, investigator 64.1%, multiple answers allowed). Conclusion: Considering scores on questions of fairness by IRB members were between 7.23-8.56 on scale of 0 to 10 point when IRB members were asked about reviewing a clinical trial protocol, it cannot be said with absolute certainty that there is no issue regarding fairness in the review process. Therefore, there should be more ways to safeguard fairness for these issues. There is a need that the disclosure amount of honorarium from sponsor should be lower than 100 million Korean won. Considering the results of the survey in which respondents expressed their thoughts, it is likely that more education on the concept of conflict of interest is needed.

• Journal of The Korean Association For Science Education
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• v.38 no.2
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• pp.219-234
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• 2018

In this study, we explored the possibility of automating the process of analyzing elements of scientific argument in the context of a Korean classroom. To gather training data, we collected 990 sentences from science education journals that illustrate the results of coding elements of argumentation according to Toulmin's argumentation structure framework. We extracted 483 sentences as a test data set from the transcription of students' discourse in scientific argumentation activities. The words and morphemes of each argument were analyzed using the Python 'KoNLPy' package and the 'Kkma' module for Korean Natural Language Processing. After constructing the 'argument-morpheme:class' matrix for 1,473 sentences, five machine learning techniques were applied to generate predictive models relating each sentences to the element of argument with which it corresponded. The accuracy of the predictive models was investigated by comparing them with the results of pre-coding by researchers and confirming the degree of agreement. The predictive model generated by the k-nearest neighbor algorithm (KNN) demonstrated the highest degree of agreement [54.04% (${\kappa}=0.22$)] when machine learning was performed with the consideration of morpheme of each sentence. The predictive model generated by the KNN exhibited higher agreement [55.07% (${\kappa}=0.24$)] when the coding results of the previous sentence were added to the prediction process. In addition, the results indicated importance of considering context of discourse by reflecting the codes of previous sentences to the analysis. The results have significance in that, it showed the possibility of automating the analysis of students' argumentation activities in Korean language by applying machine learning.

• Journal of vocational education research
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• v.37 no.3
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• pp.65-83
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• 2018

In this study, we want to analyze the aspect that required in the classroom for the operation of NCS-based curriculum, the interest of specialized subject teachers on implementable teaching and learning methods. As a result, the overall interest in teaching-learning method of specialized subject teachers was similar to that of non-user patterns among four types of interest patterns. In other words, specialized subject teachers want to know more about teaching-learning method for applying NCS-based curriculum, but we are only aware of the general facts at present, and it seems that there is low interest in actual operation. In addition, there was no statistically significant difference in the degree of interest in the teaching-learning method according to general variables(gender, related training experience, career, and curriculum group) of the specialized subject teachers. The specialized subject teachers are not well aware of the influence of the teaching-learning method according to the introduction of NCS-based curriculum, and to that end, there was little interest in collaboration with colleagues.

• Journal of the Korean earth science society
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• v.43 no.3
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• pp.430-445
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• 2022

The purpose of this study was to explore the learning effects in elementary school students who participated in a geological field trip conducted under the theme 'minerals and rocks', focusing on novelty space. A total of 10 sixth-grade students participated in this program held at a public elementary school in Seoul as part of after-school club activities. Students observed mineral and rock samples in a classroom and outdoor learning environment. The authors collected activity papers (texts, drawing), researchers' participation notes, video and audio recordings containing the study participants' activities, and post-interview data To analyze the learning effects in the cognitive domain of students, the observation analysis framework for rock classification of Remmen and Frøyland (2020) and the rock description analysis framework of Oh (2020) were used. Additionally, to explore the learning effects of psychological and geographic areas, students' drawings, texts, discourses, and interview data were inductively analyzed. The results showed that the students demonstrated 'everyday' and 'transitional' observations in the classroom learning environment, while in the outdoor learning environment (school playground, community-based activities), they demonstrated 'transitional' and 'scientific' observations. Moreover, as the scientific observation stage progressed, more types of descriptive words for rocks were used. In terms of psychological and geographic aspects, students showed their selection of places to explore familiar outdoor learning environments, positive perceptions of outdoor learning, and aesthetic appreciation. Finally, this study not only discussed novelty space as a tool for analyzing students' learning effects but also suggested the need for an academic approach considering new learning environments, such as learning through virtual field trips.

• The Journal of Sustainable Design and Educational Environment Research
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• v.22 no.4
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• pp.9-17
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• 2023

This study explores school location, school environment, educational conditions, and appropriate scale of schools in the context of Sejong City's development area and identifies effective school establishment plans based on the analysis of the needs of the educational community. The research questions for this study include, first, what is the change trend in the number of students as a result of the opening of schools in the development area of Sejong City to the present, and what differences are there between Sejong and other new cities? Second, what challenges arise in school location due to the occurrence of oversized schools and undergraduate institutions? Third, what challenges arise in school location that would limit the ability to create a safe school environment? Fourth, what aspects need to be improved in school location decisions to promote proper placement? A survey was conducted among parents and faculty members to collect data. The findings revealed that first, when establishing a school, identifying an appropriate location for the school was the top priority of the respondents. The second was the proximity of the school to dense housing, with a parent drop zone next to the school site. Third, to address the issue of lack of playgrounds and special class and care classes, respondents called for various measures such as securing school sites within a certain area. Finally, integrated operation schools and school facilities are required in preparation for decreasing school-age populations due to low birth rates.

• The Journal of the Korea Contents Association
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• v.16 no.1
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• pp.743-752
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• 2016

This study aims to investigate the overall effects of teaching grammar in the Korean EFL classroom. A meta-analysis of 67 research findings in 30 articles was conducted to synthesize the results of these studies by calculating the mean effect sizes. This study reviewed and analyzed the previous studies in terms of subjects, treatment period, and types of grammar teaching. The results showed that teaching grammar in the classroom had beneficial effects on learners in general (d=.907). It was found to be more effective for middle school and university students than for elementary and high school students (Q=37.065, df=3, p=.000). There was no statistically significant difference in terms of treatment period and types of grammar teaching. Pedagogical implications and suggestions for Korean EFL learners are also discussed.

• Journal of Korean Dental Hygiene Science
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• v.7 no.1
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• pp.17-28
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• 2024

Background: Oral health has a significant impact on systemic health, and the close association between oral and systemic diseases has been continuously reported. To prevent oral diseases, the role of oral hygiene products such as dental floss and interdental brushes, in addition to tooth brushing, is becoming increasingly important. This study aims to analyze the effect of using oral hygiene products on the lifetime prevalence of systemic diseases among Korean adults. Methods: This study utilized data from the 7th Korea National Health and Nutrition Examination Survey (2016-2018). The study population consisted of 13,199 adults aged 19 years and older. The independent variable was the use of oral hygiene products, and the dependent variable was the prevalence of systemic diseases diagnosed by a physician. Demographic variables, health status, and behavioral variables were included as covariates, and multivariable logistic regression analysis was performed. Results: The use of dental floss showed no significant association with the prevalence of systemic diseases. However, those who did not use interdental brushes had a 22% lower likelihood of dyslipidemia (OR 0.777, 95% CI 0.660-0.913). Among participants with periodontal disease, those who did not use dental floss had a significantly higher risk of myocardial infarction (OR 11.488, 95% CI 1.438-91.772). Conversely, those who did not use interdental brushes had lower risks of dyslipidemia, myocardial infarction, and angina, particularly among women and individuals under 65 years of age. Conclusion: This study found a low overall association between the use of oral hygiene products and the prevalence of systemic diseases, but there was a notable association with cardiovascular diseases. To reduce the risk of myocardial infarction, the prevention and treatment of periodontal disease, along with proper oral hygiene management, are crucial. Future prospective studies are needed to clearly establish the causal relationship between oral hygiene and systemic diseases.

• The Journal of Korean Association of Computer Education
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• v.9 no.1
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• pp.11-18
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• 2006

Many web-based learning systems have been developed and used widely. But it is known that web-based courses have higher drop out rate. Prior studies in classroom-based courses have shown there is a high correlation between student satisfaction and retention. This paper examines the developed web based self-regulated learning system and analyze self-regulated learning factors. We have derived key factors and their relationship that affect student satisfaction in web-based learning. The key factors are Self-evaluating, Goal setting & Planning, Seeking information, Seeking social assistance and Reviewing records. We found the key factors will help retention in web-based learning.