• Korean Journal of Psychosomatic Medicine
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• v.9 no.1
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• pp.58-65
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• 2001

Objectives : It is well known that pharmacologic and behavioral therapies of panic disorder show remarkable acute treatment outcome, however the course of panic disorder in clinical settings is often chronic and relapsing. The purpose of this study is to investigate the treatment outcome of panic disorder and the factors related to good treatment outcome by prospective follow-up study after 6 month in clinical settings. Methods : Twenty nine patients were diagnosed to have panic disorder by SCID(Structured Clinical Interview for DSM-III-R), among the patients who had visited the psychiatric out-patients clinic of the Asan Medical Center for the first time. We determined the initial clinical and demoraphic features of each patient and reevaluated them after 6 months, investigating the treatment outcome by anxiety, phobia, impairment scales. We looked into the rate of the patients who showed good treatment outcome and determined the factors that had relation with good treatment outcome among demographic and clinical features. Results : Nineteen out of 29 patients could be followed after 6 months. Among them, 10 patients 52.6%) on the impairment scale and phobia scale each, and 8 patients(42.1 %) on the anxiety scale showed good treatment outcome. 8 patients(42.1 %) showed good treatment outcome on the all three scales. High score in initial phobia scale had significant relation with good treatment outcome. Short duration of illness did not have significant relation with good treatment outcome however there was a trend(p=0.07). Conclusion : About half(42.1 %) of the panic disorder patients showed good treatment outcome on all three scales. Severe initial phobic symptom and short duration of illness were expected to have relation with good treatment outcome.

• The Journal of the Korea Contents Association
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• v.13 no.1
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• pp.342-353
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• 2013

The purpose of this study was to investigate the effects of short-term Maum Meditation and to compare effects according to the length of the training period on mental health of teachers. In this research, 2 types of design were used which were one-group pre-posttest design and descriptive study. In short-term Maum Meditation group, 2 times of surveys were carried out, 75 teachers in the faculty training filled out the structured questionnaire. In Long-term Maum Meditation group, 101 teachers who were attending Maum Meditation above one-year filled out the structured questionnaire. The data were analyzed by SPSS WIN 14.0 program. The results showed that there was a significant difference in mental health including 9 subscales for short-term Maum Meditation group. Also, in long-term Maum Meditation group, there were significant differences in mental health excepting paranoid ideation. It was founded that Maum Meditation is the way for the mental health promotion in short-term and long-term period. So it is necessary to develop program according to training period for not only clinical application but also to strengthen coping ability for stress.

• 월간 기계설비
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• s.323
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• pp.40-43
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• 2017

건설업 등록증 불법 대여와 무등록 건설업자 및 입찰담합 제재가 강화된 건설산업기본법 개정안이 공포됐다. 특히 불법 대여 건설업체와 공모하여 건설공사를 시공한 건축주도 처벌토록 했으며, 등록말소 처분을 받은 자의 건설업 재등록 가능연수를 10년으로 상향하는 등 불법행위 근절에 나섰다. 한편 공공기관이 현장에서 직적시공이 준수되고 있는지를 의무적으로 확인토록 하며 부실업체의 난립과 무분별한 하도급을 방지하기 위한 '직접 시공 제도'의 실효성을 확보한 것이 특징이다.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2001.05a
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• pp.511-512
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• 2001

VNN(viral nervous necrosis)는 종묘단계 및 양성장의 해산어 양식장에서 발생하는 바이러스성 질병으로 외견적으로 척추만곡, 이상유영, 체색흑화와 조직학적으로는 뇌와 망막에 공포 및 괴사를 형성하고, 또한 매우 높은 폐사율을 나타내는 질병으로 보고되어 있다. 이러한 질병은 성공적인 종묘의 생산 및 보급을 위해서 반드시 해결해야 할 사항이다. (중략)

• Korean Journal of Psychosomatic Medicine
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• v.11 no.1
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• pp.15-24
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• 2003

Objectives: The object of this study was to compare perceived stress and quality of life among patients with HIV infection, patients with pulmonary tuberculosis and normal controls. Methods: Stress response inventory(SRI) and Symptom checklist 90-Revised(SCL-90-R) were used to measure perceived stress responses and psychopathology. Smithklein Beecham quality of life scale was used to measure quality of life. Results: Patients with HIV infection scored significantly higher on scores of tension, anger, depression, fatigue and frustration subscale of the SRI than those with pulmonary tuberculosis and normal controls. Scores of the SCL-90-R, somatization, depression, anxiety, hostility, phobic anxiety, paranoid ideation and psychoticism subscale were also significantly higher in patients with HIV infection than those with pulmonary tuberculosis and normal controls. Patients with HIV infection scored significantly lower in quality of life than those with pulmonary tuberculosis. In patients with HIV infection, age had a significantly negative correlation with scores of somatization, obsessive-compulsive, interpersonal sensitivity, phobic anxiety, paranoid ideation and psychoticism subscale of the SCL-90-R. but the level of education had a significantly positive correlation with somatization, obsessive-compulsive, interpersonal sensitivity, phobic anxiety, paranoid ideation and psychoticism subscale of the SCL-90-R. Conclusion: The results suggest that patients with HIV positive were likely to have higher levels of perceived stress response and psychopathology, and lower quality of life than those with pulmonary tuberculosis and normal controls.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.2
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• pp.164-171
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• 2018

Objectives : Depression is a common mental illness and a major cause of suicide. Although serum lipids have been associated with depression and suicide, there has been much debate. In this study, we investigated the relationship between depression, suicide, and serum lipids in patients admitted with depressed mood. Methods : A total of 134 subjects were divided into 86 non-suicide patients and 48 suicide attempters. The serum lipid levels and sub-scores of the Korean Symptom Checklist-95 (KSCL95) were compared. We also investigated the relationship between serum lipids and sub-scores of KSCL95 and investigated whether serum lipids were risk factors for suicide attempts. Results : There was no difference in serum lipids between the two groups. Among the sub-items of KSCL95, obsession was higher in non-suicide group. Triglyceride showed positive correlations with anxiety, phobic anxiety, agoraphobia, schizophrenia, and self-regulation problem. High triglyceride was a risk factor for suicide attempts. Conclusions : Triglyceride is associated with depression, anxiety, and self - regulation, and high serum triglyceride levels may be a risk factor for suicide attempts.

• Korean Journal of Biological Psychiatry
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• v.13 no.3
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• pp.170-177
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• 2006

Objectives : Disturbances of serotonergic system might be related to the possible mechanism of social phobia. This study was to investigate the association of serotonin transporter gene and social phobia. Methods : Sixty nine patients with social phobia(51 male(73.9%), mean age $35.17{\pm}11.89$ years) and seventy four normal controls(54 male(73.0%), mean age $33.46{\pm}9.63$ years) were tested for serotonin transporter gene-linked polymorphic region(5-HTTLPR) polymorphism. Additionally, patients were grouped into 46 generalized(GEN) and 23 nongeneralized(NGEN) subgroups and 5-HTTLPR polymorphism was compared with that of normal controls. The genotypes and allele frequencies of the 5-HTTLPR polymorphism between social phobia and the control group were compared. Genomic DNA was extracted from their blood and 5-HTTLPR polymorphisms were determined by using polymerase chain reaction. Results : Significant association was observed between the S(ss) genotype and social phobia, by functional classification(p=.010). In allele frequency analysis, a significant association was also observed between the short allele and social phobia(p=.030). A significant associations between S genotype and each subgroup were observed(GEN p=.045 ; NGEN p=.033), but there were no differences in allele frequency. And, no differences in genotype and allele distribution between two subgroups were found. Conclusion : The results in our Korean sample suggest that S genotype of 5-HTTLPR may be associated with social phobia and s allele may be an important genetic factor that activates social phobic symptoms. But, further studies including large number of samples are necessary to elucidate these present findings.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.12
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• pp.1123-1128
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• 2009

Noise radiated from medical treatment at dental clinic will affect the patients. On such point of view, We investigated the noise characteristics in case of medical treatment (scaling, tooth eliminating) and non-medical examination (idling) and also evaluated the degree of indoor noise using the evaluation index such as PSIL, NRN and made up a questionnaire about the reactions to noise. As a result of noise evaluation, it shows that the range of noise level is 67.7~78.3 dB(A) and frequency is very high (above 4 k Hz) and respondents are affected by noise (unpleasantness, hesitation to visit dental clinic, shivering with noise, being astonishment). Analysis by PSIL showed that it was no problem to conversation between worker and patient. But it exceeded the noise permit level in working space by NR-curve. To relieve a fear of noise in patients, they are considered to offer the ear protection, choose the low noisevibration equipment and use the masking effect. They are of great advantage to dental clinics to i prove dental service and competitiveness.

• Korean Journal of Biological Psychiatry
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• v.11 no.2
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• pp.165-172
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• 2004

Objective:Although polymorphism of dopamine transporter gene(DAT1) has been considered to be implicated in the pathogenesis of social phobia, previous investigations have been inconsistent and controversial. The authors investigated the relationship between DAT1 polymorphism and social phobia in Koreans. Methods:DAT1 and alleles of fifty subjects who met DSM-IV criterion of social phobia, and those of age- & sex- matched fifty normal controls in Korea were compared. Additionally, patients were grouped into generalized(33) and nongeneralized(17) types and DAT1 polymorphism was compared with that of age- & sex- matched controls. DAT1 with variable number of tandem repeats(VNTR) were determined by using polymerase chain reaction. To compare the distribution of the DAT1 polymorphism between different groups, Fisher's exact test was used. Results:There were no significant differences in either genotypic(p=0.451) or allelic(p=0.452) distributions between the social phobia patients and the controls. There also were no differences in genotypic distribution between subtypes of social phobia patients and the controls. Conclusion:We couldn't find any association between DAT1 polymorphism and social phobia. Further studies including larger number of samples and diverse clinical variables should be conducted to elucidate the present findings.

• Korean Journal of Biological Psychiatry
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• v.16 no.1
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• pp.37-45
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• 2009

Objectives : It is reported that panic disorder is frequently comorbid with other psychiatric illnesses. The aim of this study was to investigate differences of psychiatric comorbidity according to age of onset of panic disorder. Methods : Three hundred-two patients participated in the study. All the patients were evaluated by clinical instruments for the assessment the presence of other comorbid psychiatric disorders and various clinical features; Korean version of Mini International Neuropsychiatric Interview, Self-report questionnaires(Beck Anxiety Inventory, Beck Depression Inventory, Anxiety Sensitivity Index and State-Trait Anxiety Inventory) and clinical rating scale (Hamilton Anxiety Scale, Hamilton Depression Scale and Global Assessment of Functional score). Chi-square test was used to determine the difference between early onset and late onset panic disorder. Results : Forty percent of panic patients were found to have at least one comorbid psychiatric diagnosis. There were no differences among the groups divided by number of comorbidity in sex, agoraphobia comorbidity, duration of panic disorder, except onset age of panic disorder. Early onset group had more comorbidy with social phobia, agoraphobia, PTSD. We also found that Early onset panic disorder patients were more likely to experience derealization, nausea, parethesia than late onset panic disorder patients. Conclusion : The results of our study are in keeping with previous data from other parts of the world. Our finding suggest that earier onset of panic disorder related to more psychiatric comorbidity.