• Proceedings of the KSCN Conference
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• 2004.05a
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• pp.436-437
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• 2004

폐경기성 골다공증의 치료 방법인 에스트로겐 투여에 의한 위험성을 보완하기 위해 한약재 및 식품 등 천연물의 활성성분을 이용한 대체 요법에 대한 연구가 진행되면서, 이소플라본(isoflavone)계 식물성 에스트로겐을 함유한 기능성식품의 개발이 진행되고 있다. 특히 콩과식물 중 isoflavone 함량뿐 아니라 배당체와 결합되지 않은 aglycone 함량이 높은 서목태(쥐눈이콩; 약콩)와 무기질 홉수 중진 효과를 지닌 프럭토즈폴리머(levan; beta-2,6 linked fructose polymer, ∼6,000,000 Da)를 폐경 후 여성들에게 공급하여 골형성 지표와 골흡수 지표의 변화, 혈중 칼슘 농도, 골대사를 살펴보고 골밀도의 변화를 살펴봄으로써 골다공증 예방제로서의 기능성물질의 효능을 살펴보고 신물질의 개발에 기여하고자 하였다.(중략)

• Korean Journal of Ichthyology
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• v.24 no.2
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• pp.131-134
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• 2012

A single specimen of Cyclopteropsis bergi, belonging to Cyclopteridae, Scorpaeniformes, was newly collected from Sokcho, Korea in May 2011. C. bergi is characterized by tip of 1st dorsal fin spines visible, scattered bony tubercles on body, and head without bony tubercles. New Korean name of Cyclopteropsis bergi is proposed as "kko-ma-do-chi".

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.1316-1319
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• 2003

The micromovements and stress distributions of cancellous bone in dental implant system play important roles in evaluating chewing function of an implant system. The micromovements and stress distributions in dental implant system generally depend on the chewing force and bone properties. Three dimensional nonlinear finite element analysis has been employed to investigate this issue quantitatively. Chewing forces and bone properties are classified into several groups and three types of implants involving one classical cylindrical type and two expandable implants are investigated in this paper.

• Journal of Veterinary Clinics
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• v.9 no.2
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• pp.467-472
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• 1992

Seven patients with signs of metabolic bone disease clinically seen at the Veterinary Teaching Hospital of Seoul National University from May 1990 to February 1992 were evaluated retrospectively. 1. Clinical signs include bowed leg, deformity of spine, digestive disturbance, constipation, retarded growth, lameness and hindlimb paralysis. 2. Radiographical sings include generalized skeletal demineralization, decreased radiological contrast between skeleton and soft tissues, thinning of bone cortex and pathological fractures. The diagnosis of nutritional secondary hyperparathyroidism resulting in metabolic bone disease caused by mineral imbalance was made based upon history, clinical signs, physical examination and radiographical signs.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.4
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• pp.193-199
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• 2006

Infectious and inflammatory bone diseases include a wide range of disease process, depending on the patient's age, location of infection, various causative organisms, duration from symtom onset, accompanied fracture or prior surgery, prosthesis insertion, and underlying systemic disease such as diabetes, etc. Bone infection may induce massive destruction of bones and joints, results in functional reduction and disability. The key to successful management is early diagnosis and proper treatment. Various radionuclide imaging methods including three phase bone scan, Ga-67 scan, WBC scan, and combined imaging techniques such as bone/Ga-67 scan, WBC/bone marrow scan add complementary role to the radiologic imaging modalities including plain radiography, CT and MRI. F-18 FDG PET imaging also has recently been introduced in diagnosis of infected prosthesis and chronic active osteomyelitis. Selection of proper nuclear medicine imaging method will improve the diagnostic accuracy of infections and inflammatory bone diseases, based on understading of pathogenesis and radiologic imaging findings.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2003.05a
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• pp.339-340
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• 2003

미꾸리과 Cobitidae 어류는 유우라시아 대륙의 담수역에 널리 분포하는 저서성소형 어류로 형태적으로 매우 다양하여 분류학적으로 많은 논란이 있었으나 최근 이차성징으로 나타나는 수컷 가슴지느러미의 기부에 있는 골질반의 구조와 체측 반문 그리고 지리적 분포범위의 구분 등에 관한 특징은 종 분류에 유용하게 사용되고 있다(김, 1997). Nalbant(1993)는 우리나라의 미꾸리과 어류중 기름종개속 Cobitis에 포함되었던 참종개, 왕종개, 미호종개, 부안종개를 새로운 속 Iksookimia로 기재 발표하여 김(1997)은 이를 국명으로 남방종개라 하고 인접 수역인 탐진강과 서남해로 유입되는 하천에도 이 종이 분포한다고 지적한 바 있다. (중략)

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.9 no.1
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• pp.32-36
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• 1979

The author studied on the side effects of x-ray irradiation to the developing mandible of the gestation and period of grow the stage rats. For experimental observation, 100 rads, 200 rads, and 300 rads of x-ray were irradiated in regular order at the lower abdomen of the 8th day gestated rats. 5 weeks after conception, their offspring were sacrificed and their mandibles were extracted with intact form. All the extracted mandible were examined for their developing modes histological findings. The results were as followed 1) In 100-200 rads irradiated rats offsprings, their mandidles were not revealed any morphological changes except of the irregular pattern of trabeculatum. In accompany with this findings, most of all the fibroblasts and osteoclasts had their nucleus with shrunken and eccetric position. 2) In according to the increasing x-ray irradiation, marked advent of osteoclast and cortical bone resorption were observed. 3) In 300 rads irradiated rats offsprings, there irregular pattern of trabeculae and windening of bone morrow cavity in their alveolar proper.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2006.05a
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• pp.239-242
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• 2006

골다공증은 해면골의 골소주 두께 감소 및 파단에 기인한 전체적인 골질이 저하되는 질병이다. 골다공증을 예방과 조기진단을 하기 위해서는 골밀도를 측정하여야 한다. 보다 나은 이미지를 얻기 위해 Digital X-Ray로 골밀도를 측정하여 영상 처리하기 위한 방법을 제시한다. 먼저 디지털 센서에서 증감지와 렌즈간 거리가 가까워서 증감지의 중심과 주변부의 광 경로차이가 발생하므로 왜곡이 발생하는데 이를 균일화하여야 한다. 그리고 X-Ray장비의 조건에 따라 영상에 많은 차이를 보이므로 영상의 밝기를 보정하는 과정이 필수적이다.

• The Korean Journal of Nuclear Medicine
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• v.35 no.6
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• pp.371-377
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• 2001

Purpose: One or more abnormal vertebrae detected on bone scintigraphy is a common finding in clinical practice, and it could pose a diagnostic dilemma especially in cancer patients. as either metastasis or benign disease may cause scintigraphic abnormality. The purpose of this study was to determine whether additional spine SPECT has a role in differentiating malignant from benign lesions in patients with back pain. Materials and Methods: We reviewed spine SPECT studios obtained over a three-year period in 108 patients. Among them, forty-five patients with abnormal SPECT and clinically followed records were evaluated (20 cancer patients were included). Uptake patterns were classified as follows: 1. Body: diffusely increased uptake, linear increased uptake of end plate, segmental increased uptake, and cold defect, 2. Posterior element: posterior to body (pedicle), posterior to Intervertebral disc space (facet joint), and spinous process. Lesions were correlated with radiological findings and with final diagnosis. Results: Sixty-nine bone lesions were detected on SFECT images, including 18 metastases, 28 degenerative diseases and 21 compression fractures. Cold defect (6) and segmental increased uptake (5) were dominant findings in metastasis; linear increased uptake (12), and facet joint uptake (15) were in degenerative change; and diffuse increased uptake (9), and linear increased uptake (9) were in compression fracture. Conclusion: Cold defect and segmental increased uptake of body were characteristic findings of metastasis, but care should be taken because compression fracture also shows segmental increased uptake in some cases. Degenerative disease was easily diagnosed because of the typical finding of linear increased uptake of end plate and facet joint. Therefore, additional bone SPECT after planar bone scan would be helpful for differentiating metastasis from benign condition in cancer patients.

• The Journal of Korean Academy of Prosthodontics
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• v.48 no.1
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• pp.28-40
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• 2010

Purpose: The aim of this retrospective study was to provide long-term data about the correlation between multifactorial local factors and the survival of implants. Material and methods: During 19 years (1991 to 2009), 2796 implants were placed in 879 patients. From dental charts and radiographs, the following data were collected: patient's age at implant placement, gender, implant system, surface, length, diameter, location of implant placement, bone quality, primary stability, type of prosthesis. The correlations between these data and implant survival were analyzed. Statistical analysis was performed using Kaplan-Meier survival analysis, Chi-square test, odds ratio. Results: 1. Among the 2796 implants, 150 implants failed that resulted in a cumulative survival rate of 94.64%. The cumulative survival rate of smooth surface implants (91.76%) was lower than rough surface implants (96.02%). 2. Anatomic location, implant surface, diameter of smooth surface implant, primary stability, type of prosthesis, patient's age and gender were significantly associated with implant survival (P < .05). 3. No significant difference in implant survival was found in relation to the following factors: implant length, bone quality, diameter of rough surface implants and type of rough surface according to implant manufacturer (P < .05). Conclusions: Local factors such as anatomic location, implant surface, diameter of smooth surface implant, primary stability and type of prosthesis have a significant effect on implant survival.