• Food Science and Preservation
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• v.14 no.6
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• pp.669-675
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• 2007

Quality characteristics of Kwamaegi (semi-dried saury) prepared by treatment of chitosan-ascorbate (CA) and vacuum drying at $40{\sim}60^{\circ}C$(VDK), and the effect of the Kwamaegi on serum lipid profiles and anti-oxidation-related enzyme activity in rats fed high fat diets were investigated. The preparation periods were $4.5{\sim}8.3$ hr in VDK, while naturally dried Kwamaegi (NDK) took 360480 hr. Total microbe contents of VDK and NDK were $0.2{\sim}0.5$ and 8.2 log CFU/g, respectively. There was no significant difference in amino-nitrogen content. Compared with NDK, the acid and peroxide value, and fishy flavor of VDK40 (dried at $40^{\circ}C$) were significantly lower, and the texture, color and overall acceptability were higher. In animal experiments, weight gain, content of LDL-cholesterol and lipid peroxide, activities of total (T) and O type (O) xanthine oxidase, and the O/T ratio (%) were significantly lower in the VDK40 diet group than in the NDK diet group. The content of HDL-cholesterol in the VDK40 diet group was higher than in the NDK diet group. These results suggest that preparing CA-treated Kwamaegi with vacuum-drying at $40^{\circ}C$ can be applied throughout the year, and may shorten preparation time and improve its microbiological safety and nutritional values.

• Journal of Korean Society of Forest Science
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• v.101 no.1
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• pp.69-76
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• 2012

We investigated the effect of mountain ginseng-added high fat diet supplementation on lipid peroxidation and antioxidant protein expressions in rats. Thirty-two male rats were randomly divided into 4 groups; HS (high-fat diet sedentary group, n=8), MG1 (0.5% mountain ginseng-added diet group, n=8), MG2 (1% mountain ginsengadded diet group, n=8) and MG3 (2% mountain ginseng-added diet group, n=8). They have fed the diet for 4 weeks. The blood triglyceride were significantly lower in the MG1 and MG2 groups than that of the HS group. The blood HDL-cholesterol were significantly higher in the MG3 group than that of the HS and MG2 groups. The muscle glycogen contents of the MG2 and MG3 groups were significantly higher than that of HS and MG1 groups. The MDA contents in the MG1, MG2 and MG3 groups tended to lower than the HS group. The GPx protein expression in the gastrocnemius muscle of the MG2 group was significantly increased compared to that of the HS group. The Cu,Zn-SOD protein expression in the gastrocnemius muscle of the MG1 and MG2 groups was significantly increased compared to that of the MG3 group. The Mn-SOD protein expression in the MG1, MG2 and MG3 groups tended to higher than the HS group. From these results, it was suggested that mountain ginseng-added diet may have an crucial role on decreased MDA levels and increased antioxidant function in the skeletal muscle of rat fed a high fat diet.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.571-579
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• 2019

To minimize the damage from chemical accidents, a risk management plan (RMP) has been implemented since 2015. According to this regulation, operators who handle more than the designated quantity of the accident preparedness chemicals should provide emergency response information to the public within the affected areas of accidents. The information, including chemicals, affected areas and evacuation instructions should be provided to the public in advance so that they can evacuate immediately in the event of a chemical accident. Currently, the information notification can be provided in various methods by being registered in the notification system, sent with written documents or delivered directly to the public. To examine the status of the operation method, this study analyzed similar cases overseas, investigated the degree of awareness of providing information through the number of the annual visitor of the Information Provision System, and obtained survey results from some residents. This current operation method are problems because the public, who do not have sufficient information about chemicals, do not understand the emergency information properly or it is difficult to recognize where the residents should find this information because of the convenient operation based on the information provider. In this study, measures were proposed to minimize the damage by making it easier for the public to understand the emergency information and the information communicated appropriately in advance by dividing them into an information providing method and post management.

• Journal of Yeungnam Medical Science
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• v.16 no.1
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• pp.34-42
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• 1999

The effects of hyperglycemia and hyperlipidemia on utilization of muscle glycogen during 45 minute Session of treadmill running(26 m/min, 8% grade) were evaluated using Sprague Dawley rats, and the characteristics of the 4 different type of muscles, I.e., soleus, white and red gastrocnemius, and plantaris, on glycogen utilization were simultaneously investigated. Hyperglycemia was induced by 145-165 mg/dL of oral glucose administration, and hyperlipidemia was induced by combined treatment of intraperitoneal heparine injection of 444 uEq/L and 10 % intralipose oral adminstration. During the hyperglycemic trial, the glycogen utilization of plantaris muscle was decreased by 13 % in 45 minute session of treadmill running compared to the control trial(p<0.05), and the glycogen utilization of white gastrocnemius was also decreased. The sparing tendency of glycogen was observed in soleus and red gastrocnemius by 5-13 % during 30 and 45 minute session of treadmill running in hyperglycemic trial. There was no glycogen sparing effect of hyperlipidemia in soleus, red gastrocnemius and plantaris muscle subjected in this experiment during exercise. However, only a slight sparing tendency of white gastrocnemius muscle was observed. In summary, the glycogen sparing effect of hyperglycemia during exercise was observed in plantaris and white gastrocnemius muscles in rats. However, there was no glycogen sparing effect of hyperlipidemia in the 4 hindlimb muscles. It was observed that the glycogen sparing effect of hyperglycemia is more prominent in fast glycolytic muscle fibers.

• Journal of Life Science
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• v.31 no.5
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• pp.488-495
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• 2021

The aim of this study was to investigate the possible antioxidant effect of Spirodela polyrhiza (SP) on rats fed a high fat and high cholesterol diet supplemented with either 5% (SPA group) or 10% (SPB group) SP for 4 weeks. The hepatic SOD activity of the HF group significantly decreased compared to that of the N group, but that of the SPA and SPB groups significantly increased. The GPx activity of the SPA and SPB groups in the liver was significantly greater than that of the HF group, and the hepatic catalase activity of the SPA and SPB groups significantly increased compared to the HF group. The hepatic superoxide radical content of the mitochondria and microsomes of the HF group significantly increased compared to that of the N group, but the contents were reduced in the group that took SP powder. The hepatic hydrogen peroxide content in the cytosol and mitochondria of the SP powder group was lower than in the HF group. The carbonyl content in the mitochondria and microsomes of the SPA and SPB groups was significantly lower than in the HF group. The TBARS values in the liver significantly decreased in the SPA and SPB groups. Spirodela polyrhiza was thus effective in reducing oxidative stress by regulating the hepatic antioxidant enzymes and the free radicals in rats fed high fat and high cholesterol diets.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2017.05a
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• pp.73-73
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• 2017

환경부는 화학물질로 인한 국민건강 및 환경상의 위해(危害)를 예방하고 화학물질을 적절하게 관리하고, 화학물질로 인하여 발생하는 사고에 신속히 대응함으로써 화학물질로부터 모든 국민의 생명과 재산 및 환경을 보호하기위한 법률인 "화학물질관리법"을 2015년 1월 1일부터 시행하였다. 화학물질관리법에서는 유해화학물질의 취급기준과 유해화학물질 취급시설의 설치 및 관리 기준을 준수토록 하고 있으며, 유해화학물질 취급시설을 설치 및 운영 시에는 사전에 화학사고 발생으로 사업장 주변 지역의 사람이나 환경 등에 미치는 영향을 평가하여 유해화학물질 취급시설의 설치단계에서 안전성을 확보하기 위한 유해화학물질 화학사고 장외영향평가서를 작성 및 제출하도록 하고 있다. 또한 사고대비물질을 규정 수량이상 취급하는 경우 위해관리계획서를 작성하여 지역사회에 고지하도록 하고 있다. 법 시행 이전에 유해화학물질 취급시설을 설치한 사업장은 사업장 규모에 따라 장외영향평가서의 제출 유예기간인 2019년 12월 31일까지 제출하여야 하며, 사고 대비물질의 영업허가를 득해야하는 사업장은 2017년 내 장외영향평가서를 제출하여야 한다. 장외영향평가(off-site risk assessment(ORA)) 제도는 유해화학물질 취급시설의 기본평가정보(공정 정보), 장외평가정보(사고 시나리오 선정 및 위험도 분석), 타 법령과의 관계정보로 구성되어 있다. 장외영향평가의 효율적인 작성을 위하여 현장과 일치된 공정정보(공정개요 및 공정도면 등의 자료)의 확보가 필수적이다. 본 발표에서는 복잡한 장외영향평가 제도로부터 기업의 대응을 위한 장외영향평가 운영 절차와 장외영향평가서의 효율적인 작성을 위한 사전 준비 자료 및 작성 방안을 제시하여, 사업장에서 장외영향평가 제도를 이행하는데 도움을 주고자 한다.

• Journal of Food Hygiene and Safety
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• v.34 no.4
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• pp.388-395
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• 2019

The object of the present study was to examine the effect of selenium-treated Spinacia oleracea L. on antioxidative defense system and oxidative damage in rats fed high-fat and high-cholesterol diets. Experimental rats were divided into six groups which were composed of normal diet group (N), high-fat and high-cholesterol diet group (HF), high-fat and high-cholesterol diet with 5% or 10% non-treated spinach supplemented group (SPA or SPB) and high-fat and high-cholesterol diet with 5% or 10% selenium-treated spinach-supplemented group (SSA or SSB). In the antioxidant enzyme activities of hepatic glutathione peroxidase and superoxide dismutase, activities increased in supplementation of non-treated or selenium-treated spinach groups compared to HF group. However, there was no significant difference in the activity of hepatic catalase among all experimental groups. The microsomal superoxide radical content of the SSB group was significantly reduced compared to the HF group. The mitochondrial carbonyl values of the SSB group were significantly reduced compared to the HF group. Thiobarbituric acid reaction substance (TBARS) values in RBC and liver were also reduced in non-treated or selenium-treated spinach-supplemented groups compared to the HF group. The hepatic TBARS values of the supplementation of selenium-treated spinach groups significantly decreased compared to the supplementation of non-treated spinach groups. These results suggest that selenium-treated spinach may reduce oxidative damage by the activation of antioxidative defense system in rats fed high-fat and high-cholesterol diets.

• Journal of Korean Academy of Rural Health Nursing
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• v.8 no.2
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• pp.65-73
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• 2013

Purpose: The purpose of this study was to identify the relationship between intention to use advance directives and level of death anxiety in community-dwelling elders. Method: The participants were 200 older adults who were aged 60 or over and attended the community welfare centers. The level intention to use advance directive was measured by a questionnaire that was developed by the authors for the study. The measure by Kraus and Ellisond was administered to evaluate the level of death anxiety. Result: The average score for intention to use advance directives was $2.05{\pm}0.88$ and that of death anxiety was $6.2{\pm}2.28$. There were significant differences in the intention to use advance directives according to education levels and individual properties. Although there was no significant relationship between the intention to use advance directives and the level of death anxiety, they were negatively associated. Therefore, older adults who had lower death anxiety would tend to use advance directives. Conclusion: It would be necessary to screening the level of death anxiety to promote use of the advance directives. In addition, education programs for advance directives would be essential to consider about advance directives for their end-of-life especially for the community-dwelling elderly in Korea.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2001.04a
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• pp.90-90
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• 2001

1980년대 중반이후 국내에서는 기존의 로진-알람을 이용한 산성 초지 대신 중성 초지 로의 전환이 가속화 되어왔다. 현재 거의 모든 지종이 중성 초지 조건에서 생산되고 있으며 A ASA(alkenyl succinic anhydride)와 함께 대표적 중성 사이즈제로 널리 쓰이고 있는 A AKD(alkyl ketene climer)를 이용한 중성 사이징이 주류를 이루고 있다. 따라서 본 연구에 서는 국내에서 가장 많이 사용되고 있는 AKD를 이용한 중성 사이정의 효과를 파악하기 위 하여 지료 조성에 따른 AKD의 사이즈 발현 특성을 알아보고자 하였다. 공시펼프로는 미세분이 적은 미고해 NBKP와 신문고지를 실험실에서 탈묵한 DIP를 사 용하였으며, 정착제로는 PAM 및 분자량과 전하밀도가 서로 다른 3종의 Polyamine을 사용 하였다. 충전제로는 현장에서 사용되는 공업용 Clay, Talc와 탄산칼습을 사용하였다. 각기 다른 지료 조성에서 AKD 사이즈도의 발현과 효과를 조사한 결과 다음과 같은 결론을 얻었다. 일반적으로 미세분의 제거, 섬유손상의 억제, 적절한 정착제의 사용, 열처리 등의 조건 들이 갖추어 질 때 AKD의 사이정 효율을 보다 높일 수 있었다. 탄산칼습이나 Talc같은 낮 은 표면 에너지를 가지는 충전물들은 AKD 사이정에 긍정적인 효과를 나타내었다. 정착제 로서의 PAM의 첨가는 DIP에서 Polyamine보다 낮은 사이즈도를 보였으나 NBKP에서는 더 효과적이였다. Polyamine은 소량 투입만으로 일정수준의 사이즈도를 나타낼 수 있는 정착제 로 특히 DIP 사이정에 상당히 효과적이였으나 사용량과 충전물의 첨가에 매우 민감하게 반 응하였다.

• Conservation Science in Museum
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• v.3
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• pp.21-27
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• 2001

In National Central Museum, we recently preserved paper cultural assets, such as ancient maps, books and antique documents etc, to prepare "A Dynamic World of External Relations in Goryeo & Joseon Dynasty". The paper cultural assets generally react sensitively to their environments; temperature, humidity, light and physical force acting. Biological damages, which are caused by microbe, contraction, swelling and damage from insects occurred. Wrinkles on relics, which are made my physical force, stains on relics which are due to moisture, weakening of adhesive strength and damages from insects were found during the recent preservation handling. Therefore we are trying to find out any damage, which could be occurred in paper cultural assets and introduce brief emergency operation to prevent the damages and develop the preservation handling.