• Journal of Ginseng Research
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• v.33 no.3
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• pp.229-233
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• 2009

The centrifugal coating granulating system, a new method of preparing red ginseng extract pills, has been developed. The red ginseng extract was first powdered with 85.5% of edible ethanol and dried for 3 to 4 hours at 50$^{\circ}C$. The powders were fed in chamber of centrifugal coating granulating system and then granulated, sequentially. The centrifugal system operated at 20 to 50$^{\circ}C$ of inlet temperature, 1 to 1,000 g/min of feeding speed, 60 to 70$^{\circ}C$ of atmosphere temperature of intake, 3.0 to 4.0 bar of spray atmosphere pressure, 1,000 to 1,500 rpm of centrifugal plate speed and 25 to 40$^{\circ}C$ of outlet temperature. The product yield was about 85% and preparation time was 7 to 8 hours. Especially, major ginsenoside components of red ginseng were not decomposed after processing of red ginseng extract pill.

• Korean Journal of Plant Resources
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• v.19 no.1
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• pp.133-138
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• 2006

In order to enhance the components of bioactive ginsenosides and the manufacturing process of red ginseng, we developed the simplified method for red ginseng production. The red ginseng extract was prepared from red ginseng produced with the simplified method, and the production rate of extract ($62^{\circ}$ brix) was more than 60%. The ginsenosides of red ginseng were purified and analyzed by HPLC using ELSD. Ginsenoside-$Rg_3,\;Rh_2$ and $Rh_1$, specific artifacts found only in red ginseng, were detected by HPLC. Especially, contents of ginsenoside-$Rg_3$ and Rh1 were detected high than two times in red ginseng produced the simplified method compared to commercial products.

• Journal of Ginseng Research
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• v.32 no.4
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• pp.332-336
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• 2008

Red ginseng is classified according to outer form and the quality of internal tissue, and red ginseng below third grade can't be sold. Also there are many differences in price according to grade. So if inferior Red ginseng is sold, economic loss and claim take place. This research is done conducted to investigate the possibility of the non-destruction internal tissue investigation of red ginseng. It is observed and compared that MR image after getting MR image agrees with real cutting side in 10-13% water content of red ginseng. The MR image can be obtained to see the internal section of red ginseng with equal condition of time, temperature and slice thickness in spin echo pulse sequence. The MR signal of red ginseng is very weak, because it contains low water density. So it takes about 30 minutes with the measurement of single point image (SPI). But the suitable time to distinguish internal tissues is about 9 seconds in TE (Echo Time) 2.23 ms, TR (Repetition Time) 150ms. The image to discriminate internal tissues in 9 seconds can be obtained when slice thickness is 10 mm with changes of 3, 5, 10 mm. The image obtained after 30 minutes' boiling of 55 degrees has clearer image than that of normal temperature. It is thought that MR signal is stronger through active motion of water particles as temperature increases. With this method MR image of red ginseng can be obtained and characteristics of internal tissues can be observed in such a short time.

• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.2
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• pp.256-260
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• 2008

In this study, the composition of saponin and physico-chemical properties of Korean red ginseng extract was analyzed based on various extracting conditions. The total saponin and individual ginsenoside concentration of the red ginseng extract showed a decreasing trend as the extracting temperature and time increased; also, the extracting condition at $75^{\circ}C$ for 24 hours showed the highest concentration. In contrast, the concentration of $Rg_3$ increased as the extracting temperature and time increased within the particular range. It was suggested that a certain part of ginsenosides changes to $Rg_3$ according to extracting conditions; thus, the concentration of $Rg_3$ increased. Physico-chemical properties of Korean red ginseng extract based on the extracting conditions were different compared to those for saponin; so, as the extracting temperature and time increased, brix and color difference increased but pH decreased indicating stabilization of the overall quality of the product. Therefore, the most appropriate extracting condition for both the product quality of Korean red ginseng extract and stable extraction of saponin was $80^{\circ}C$ within 48 hours, minimizing the loss of ginsenosides.

• Journal of Ginseng Research
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• v.13 no.2
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• pp.169-173
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• 1989

Seven year old ginseng was investigated for yield , the relationship between yield and percent missing plant and red ginseng quality. Yield was 2.06 kg/kan (3.3 m2) and percent missing plant was 27.1%. The highest yield plot showed 3.58 kg/kan and potential yield appeared to be 4.5 kg/kan. Yields of 1st, End and 3rd line showed significant negative linear correlation with percent missing plant. Potential yield without missing plant was in decreasing order of 1>2)3>5) 4 and negatively correlated with unit yield decrease per percent missing plant. Potential yield of 1st line was 6.56 kg/tan. Soft X-ray absorbtion characteristics was not different from that of 6 year old ginseng. Red ginseng grade and percent occurence of red ginseng quality factors were not different from those of 6 years old ginseng. The weight of red ginseng per root was much greater than that of 6 years ginseng. In view of yield and quality of fresh and red ginseng the production of red ginseng from 7 years old ginseng appears to be economically feasible.

• Proceedings of the Ginseng society Conference
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• 1984.09a
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• pp.215-223
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• 1984

Panax ginseng has often been suggested as a geriatric restorative. This study is a double blind crossover trial to test whether ginseng can improve function in subjects with the depression and reduced abilities associated with senescence. 49 screened subjects were given 1500 mg Korean Red ginseng and identical placebo each for ten days, with a washout period in between the dosages. Standard tests of mental function, neuromuscular reflexes, responsiveness, mood and well being were used. The subjects were somewhat better at the co-ordination and speed test ('number copying') but tests of concentration and memory ('Concentration', 'Paired Association', 'Digit Span' and 'Object Learning') gave equivocal results. There were small improvements in mood and well being ('Life Satisfaction' and 'General Health Questionnaire') while the subjects indicated increased energy, alertness and less sleep, but also less happiness on the daily analogue scales. The major result was a highly significant improvement in reactivity, speed and co-oridnation at the tapping test, and the visual, auditory and disjunctive reaction timer. These are the most objective and accurate tests used in this trial. It is therefore concluded that ginseng can increase function in senile individuals. This effect is most easily visualisable in objective psychophysical tests, rather than the more subjective memory and concentration tests.

• Proceedings of the Ginseng society Conference
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• 1988.08a
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• pp.87-91
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• 1988

We studied the effects of red ginseng on blood pressure (BP) and the quality of life (QOL) in 19 hypertensive patients treated with antihypertensive agents. Red ginseng was administered at a dosage of three grams a day for three months. Systolic blood pressure was significantly lowered during the administration period of red ginseng. while diastolic blood pressure and hear1 rate remained unchanged. QOL was significantly improved in $89\%$ of the patients. Among the QOL variables. sleep disorder. thirst. fatigue. mood. sexual life and general well-being were improved. Furthermore. an improved coefficient of variation of R-R intervals $(CV_{R-R})$ was observed during the period. A month after the cessation of red ginseng systolic blood pressure returned to the level before the administration and QOL variables detariorated to previous pre-treatment states. These results suggest that red ginsing may lower systolic blood pressure and may improve QOL in patients treated with antihypertensive agents.

• Proceedings of the Ginseng society Conference
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• 2003.05a
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• pp.48-48
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• 2003

• Proceedings of the Ginseng society Conference
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• 2004.05a
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• pp.48-49
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• 2004

• The Korean Ginseng Research and Industry
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• v.4 no.1
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• pp.7-19
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• 2010