• Applied Chemistry for Engineering
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• v.26 no.4
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• pp.470-476
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• 2015

In this study, three dicaffeoylquinic acids (DCQAs) isolated from Gnaphalium affine D. DON. extracts were structurally identified and evaluated for their antioxidant activities, cellular protective effects, and tyrosinase inhibitory activities. The ethyl acetate fraction of G. affine was chromatographed, which yielded 3 DCQA derivatives of 1-3 : 3,5-dicaffoylquinic acid (3,5-DCQA, 1), 4,5-dicaffeoylquinic acid (4,5-DCQA, 2), 1,5-dicaffoylquinic acid (1,5-DCQA, 3). The structure of each compounds was determined using $^1H$ NMR and MS analyses. Compounds of 1-3 showed strong free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activities ($FSC_{50}=3.70$, 5.80, and $5.50{\mu}M$, respectively) compared to those of a commonly used lipophilic antioxidant, (+)-${\alpha}$-tocopherol ($21.90{\mu}M$). Cellular protective effects of 1-3 compounds on the $^1O_2$ sensitized photohemolysis of human erythrocytes were similar to (+)-${\alpha}$-tocopherol. 1-3 compounds also exhibited higher tyrosinase inhibitory effects ($IC_{50}=0.15$, 0.16, and 0.13 mM) compared to arbutin (0.33 mM), known as a skin-whitening agent. These results indicate that three DCQA derivatives may be applied as an antioxidant and a skin whitening agent in food or cosmetic industries.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.670-675
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• 2016

Both melting temperature and enthalpy of MBCA/DMTDA mixtures were measured as a function of DMTDA compositions using DSC. The thermal properties of polyurethane elastomer samples prepared with MBCA, DMTDA, and 40/60 MBCA/DMTDA mixture as curing agents were also observed using TGA. MBCA and DMTDA showed good miscibility over the entire composition range, exhibiting individual DSC melting peaks. Peak temperatures were non-linearly reduced as DMTDA concentrations increased, being approximately $60^{\circ}C$ in the case of the 40/60 MBCA/DMTDA mixture. Furthermore, melting enthalpy of the mixture was calculated as 3.8 J/g, which was only 4.3% compared to 87.3 J/g of MBCA. Based on these results, crystallization of the mixture was considered to occur very slowly, and the fluidic gel-state of the mixture was visually confirmed to be maintained over 5 days at room temperature. Thermal decomposition of polyurethane elastomer prepared with 40/60 MBCA/DMTDA curative started at about $190^{\circ}C$, which is similar to that observed for DMTDA, only except decomposition behavior over higher temperature of $400^{\circ}C$.

• Korean Journal of Food Science and Technology
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• v.47 no.6
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• pp.757-764
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• 2015

Red ginseng was treated by subcritical water extraction (SWE) whose two parameters were the extraction temperature ($105-150^{\circ}C$) and time (5-20 min) under a high pressure. The oBrix value, solid content, color difference, and turbidity of the red ginseng extract increased with increasing extraction time and temperature, while the pH decreased. The total concentration of ginsenosides in the red ginseng extract was maximal at $120^{\circ}C$ and 20 min. The concentrations of ginsenosides Rg3 and Rh1 were maximal at $150^{\circ}C$ and 15 min. The concentrations of Rg3 and Rh1 were respectively 3.5-5 times and 2-2.5 times higher than those treated by conventional extraction methods with hot water, ethanol, and methanol. SWE is a particularly effective method for the selective extraction of less-polar ginsenosides such as Rg3 which is well known to exert strong anticancer effects.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.2 no.1
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• pp.27-33
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• 2009

Generally, implantable microphone has been implanted in the temporal bone for implantable middle ear hearing devices (IMEHDs). In this case, the microphone's membrane can be damaged and can be generated biological noise. In order to overcome the these problems, the location of implanted microphone should be changed. As an alternative, the microphone can be implanted in the external auditory canal. However, the sound emission can be produced because of vibration transducer toward reverse direction from the tympanic membrane to the external auditory canal. In this paper, an amount of the emitted sound is measured using a probe microphone as the changing the position of microphone in the external auditory canal of a physical ear model, which is similar to acoustical and vibratory properties of the human ear. Through the measured value, the location of the microphone was assumed in the external auditory canal. According to the analysis, the microphone input sound can be decreased when microphone position become more distance from the tympanic membrane in the auditory canal. However, the external auditory canal is not appropriated to implantable microphone position, because sound emission is not completely eliminated.

• Journal of Korean Society of Environmental Engineers
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• v.30 no.2
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• pp.175-180
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• 2008

The objective of this study was to investigate biosorption of organic matter on EPS(Extracellular Polymeric Substances) at different SRT(Sludge Retention Time) in a SBR(Sequencing Batch Reactor) process, which was operated with the following operation steps : Fill-React-Settle-Decant-Idle. The hydraulic retention time was set to be 24 hours. The results obtained from this study showed that the organic removal efficiency per unit microbial biomass decreased with increasing SRT, and the corresponding EPS amount also did. The percent removal of organic by biosorption increased with SRT, and it reached to 53.2% at SRT of 30 days. However, the highest biosorption per microbial biomass(48.6 mgCOD/gVSS) was found at SRT of 2 days. The EPS analysis was performed by measuring TSS, TCOD$_{Cr}$, and TKN. The EPS production per unit microbial biomass was observed to be high at a low SRT. Due to the above result, the floc formation was hindered and therefore poor settlement of sludge resulted in decreasing the COD removal efficiency. It was therefore concluded that the consideration of the system design should include the characteristic of EPS as well as other factors such as SRT, MLSS, and organic loading.

• Journal of the Korean earth science society
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• v.30 no.7
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• pp.909-927
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• 2009

Inquiry became an essential methodology in science education. Recently, argumentation becomes more important in inquiry, but inquiry-based teaching in school science would not provide enough opportunities for students to have voluntary and active interactions during inquiry activities. Informal science learning can be an alternative for authentic inquiry. Accordingly, this study aims to find interaction patterns in dialogic inquiry of junior high school students in small groups in the natural history gallery. Inquiry elements and interaction patterns are analyzed with 42 dialogues of 13 small groups. As a result, seven interaction patterns are identified. First, five major interaction patterns were drawn as follows; Sharing questions, asking questions and simple response, asking questions and simple explanation, asking questions-simple explanation-(collecting data)-data based explanation, and asking questions-collecting data-data based explanation. Second, pattern 2, 'asking questions and simple response', is subdivided into three categories; passive and/or evasive response, inaccurate response, and repeated patterns of asking questions-simple response. The results of the study provide different patterns of dialogic interactions in a small group inquiry in informal contexts from formal contexts, and provide foundations to understand middle school students' interactive dialogues of inquiry occurred in the natural history gallery.

• Archives of design research
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• v.18 no.4 s.62
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• pp.185-194
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• 2005

In the perspective of hybrid, design contains confused forms and styles. Thus, the question is what 'decisively affects' on life, happiness and peace of human beings: In the past scientific ecology that tries to solve the problem in the aspect of functional design was important. Now the question is beyond the scientific ecology because human has a different way of environmental adaptation from animals. From this point of view, design is defined as something beyond materialistic standard. Terry Eagleton said, 'Creative ability deviating oneself and transcending is the very standard to measure human beings' A tendency to hybridize one's own section off genre or pursuing dismantlement is found on such creative perspective. In other words, it focuses on making a space of human's cultural behavior by unifying creatively natural environment and architecture space in the organic aspect. Such phenomenon provides a new chance and possibility in environmental design through a new molding experiment according to the development of digital technology. As experiments of environment design using digital technology are actively implemented, ecological and cultural views hybridize to create a new cultural space of various functions and features. Such experiment in environment design highlights the connections of ecological view, recognition of value, and relation-centered ideas, and enables a tool pursuing a new cultural development. This study focuses on the paradigm of such digital hybrid design and purposes to set the system by analyzing the application styles and principles of environment design through theoretical and case studies. In addition, it promotes a new possibility to develop environment design in the history of civilization.

• Radiation Oncology Journal
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• v.13 no.1
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• pp.1-7
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• 1995

Purpose : To evaluate the efficacy of radiotherapy for the low-grade astrocy-tomas and confirm the variables influencing treatment results. Materials and Methods : Forty-six patients with low-grade astrocytoma received radiotherapy after surgical removal (36 patients) or biopsy (10 patients) from 1979 to 1990. Twenty patients had grade I histology and 26 had grade II. External radiotherapy was done by conventional schedule with the total dose of 45 to 60 Gy (median: 54 Gy). The median follow-up period was 5 years. Results : The 2- and 5-year survival rates were $80\%$ and $72\%$, respectively and the 2- and 5-year progression-free survival was $75\%$ and $63\%$, respectively. The survival was influenced significantly by the histologic grade, the histologic type, and performance status. Major complication was not found. Conclusion: In spite of good survival, the local failure was still the major problem. Age and the extent of surgery as well as three favorable factors should be considered in the future treatments.

• International Commerce and Information Review
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• v.19 no.1
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• pp.155-187
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• 2017

In the US, the Sections 301 of the Trade Act of 1974 are still being used to resolve disputes. The U.S' such unilateral retaliations grounded on the Sections 301 of the Trade Act, in fact, violate the WTO agreements and hinder the development of international trade as the trade partner may assume it as a reprisal move impeding the fair settlement of disputes. Here, this study is going to examine the characteristics and functions of the WTO dispute settlement system briefly and compare the countermeasures recognized to be legitimate by the WTO with the U.S' unilateral retaliation. Also, this author will analyse the US-Japan Automobiles (DS6) and EC-Bananas III (DS27) as one of the typical cases resulted from the unilateral retaliation. According to the result, these cases do not conform to WTO-consistency, and it implies that it is absurd to accept the US' unilateral retaliation internationally. In conclusion, presently, it is a global trend to solidify protectionism, and to vitalize trade and resolve trade disputes efficiently, it is needed to prohibit the recourse to unilateral retaliations and also positively apply the WTO dispute settlement system(DSU) defining rules about how to strengthen the multilateral system.

• Journal of Global Scholars of Marketing Science
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• v.7
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• pp.353-374
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• 2001

Price and brand are two major attributes of products that consumer purchases. Price is important because it is often a measure of worth and quality. Some consumers purchase only well-known national brands. However, By reason of the price competition on account of new business condition and depressions, and consumers practical and rational purchasing tendency, consumers tend to purchase private brands(PB hereafter) because as consumers they expect that producers have reasonable and acceptable quality. Accordingly, The study, with intrinsic cue, extrinsic cue, familiarity anything like these cues from the study of Richardson et aI(1994, 1996), intends to present current topics we guide in retailer's promotion strategy for PB. As for investigating how quality evaluation has on effect on the private brands purchasing behavior of discount store grocery items. This study establishes a hypotheses on the basis of the quality evaluation cues of PB and literature review for purchasing behavior and collects materials for consumers about 196, and also analyzes them using a variety of SPSS/PC+package program. Therefore, the findings of this study provide the following managerial implications. 1) Retailer will successful in increasing private brand market share through dramatic improvement in package design, labeling, advertising, and branding strategies. 2) Planned Purchasers have high intention to repurchase PB because they buy them reasonably in accordance with the estimate therefore, they might have word-of-mouth effect for the evaluation of quality and recognition. They need to acknowledge benefits for PB purchases to maintain purchase like that. 3) The main consumers are housewives in their thirties and forties and they something reasonably because they have a lot of family and retailer will work out.