• The Korean Journal of Applied Statistics
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• v.21 no.1
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• pp.1-17
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• 2008

The ordinary least squares regression method of Haseman and Elston(1972) is most widely used in genetic linkage studies for continuous traits of sib pairs. Kruglyak and Lander(1995) suggested a statistic which appears to be a nonparametric counterpart to the Haseman and Elston(1972)'s regression method, but in fact these two methods are quite different. In this paper the relationships between these two methods are described and will be compared by simulation studies. One of the characteristics of the sib-pair linkage study is that the explanatory variable has only three different values and thus dependent variable is heavily replicated in each value of the explanatory variable. We propose a weighted least squares regression method which is more appropriate to this situation and the efficiency of the weighted regression in genetic linkage study was explored with normal and non-normal simulated continuous traits data. Simulation studies demonstrated that the weighted regression is more powerful than other tests.

• Journal of the Korea Society of Computer and Information
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• v.26 no.8
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• pp.157-164
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• 2021

Regression analysis is a well-known statistical technique useful to explain the relationship between response variable and predictor variables. In particular, Researchers are interested in comparing the regression coefficients(intercepts and slopes) of the models in two independent populations. The Chow test, proposed by Gregory Chow, is one of the most commonly used methods for comparing regression models and for testing the presence of a structural break in linear models. In this study, we propose the use of permutation method and compare it with Chow test analysis for testing the equality of two independent linear regression models. Then simulation study is conducted to examine the powers of permutation test and Chow test.

• Journal of the Korea Society of Computer and Information
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• v.25 no.7
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• pp.175-182
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• 2020

Fisher's classical method for combining independent p-values from continuous distributions is widely used but it is known to be inadequate for combining p-values from discrete probability distributions. Instead, the discrete analog of Fisher's classical method is used as an alternative for combining p-values from discrete distributions. In this paper, firstly we obtain p-values from discrete probability distributions associated with multi-sample location test data (Fisher-Pitman test and Kruskall-Wallis test data) by permutation method, and secondly combine the permutaion p-values by the discrete analog of Fisher's classical method. And we finally compare the combined p-values from both the discrete analog of Fisher's classical method and Fisher's classical method.

• The Korean Journal of Applied Statistics
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• v.30 no.6
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• pp.931-941
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• 2017

Typical Nonparametric methods for randomized block design with replications are two methods proposed by Mack (1981) and Mack and Skillings (1980). This method is likely to cause information loss because it uses the average of repeated observations instead of each repeated observation in the processing of each block. In order to compensate for this, we proposed a test method using linear placement statistics, which is a score function applied to the joint placement method proposed by Chung and Kim (2007). Monte Carlo simulation study is adapted to compare the power with previous methods.

• Journal of the Korean Data and Information Science Society
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• v.21 no.6
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• pp.1243-1251
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• 2010

For clinical trials, it is common to compare the placebo and new drug. The method of calculating a sample size for two independent populations are the t-test that is used for parametric methods, and the Wilcoxon rank-sum test that is used in the non-parametric methods. In this paper, we propose a method that is using Kim's (1994) statistic power based on the linear placement statistic, which was proposed by Orban and Wolfe (1982). We also compare the sample size for the proposed method with that for using Wang et al. (2003)'s sample size formula which is based on Wilcoxon rank-sum test, and with that of t-test for parametric methods.

• Journal of the Korean Data and Information Science Society
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• v.28 no.4
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• pp.733-742
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• 2017

There are many areas of applications where Gumbel distribution are employed such as environmental sciences, system reliability and hydrology. The goodness-of-fit test for Gumbel distribution is very important in environmental sciences, system reliability and hydrology data analysis. Therefore, we propose the two test statistics to test goodness-of-fit for the Gumbel distribution based on the generalized Lorenz curve. We compare the new test statistic with the Anderson - Darling test, Cramer - vonMises test, and modified Anderson - Darling test in terms of the power of the test through by Monte Carlo method. As a result, the new test statistics are more powerful than the other test statistics. Also, we propose new graphic method to goodness-of-fit test for the Gumbel distribution based on the generalized Lorenz curve.

• Communications for Statistical Applications and Methods
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• v.4 no.1
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• pp.41-47
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• 1997

본 연구의 목적은 p변량 관측지가 등상관구조를 갖는 경우 주변분산들의 균일성을 검정하는 통계적 절차를 개발하는 것이다. 이를 위하여 2변량의 경우에 적용되는 피트만(Pitman)의 방법을 3변량 이상의 경우로 확장하고 피셔(Fisher)의 임의화 검정을 적용하여 정규분포의 틀에 의존하지 않는 p 값을 산출한다.

• KOREAN POULTRY JOURNAL
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• v.18 no.1 s.195
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• pp.160-162
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• 1986

농수산부는 축산법시행규칙 제6조의 3 제2항 규정에 의거 종축검정방법을 고시하였다.(농수산고시 제85-59호, 85. 11. 18) 이 중 닭 검정요령을 발췌 게재한다.

• Journal of the Korean Data and Information Science Society
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• v.25 no.5
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• pp.971-986
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• 2014

When thousands of hypotheses are tested simultaneously, the probability of rejecting any true hypotheses increases, and large multiplicity problems are generated. To solve these problems, researchers have proposed different approaches to multiple testing methods, considering family-wise error rate (FWER), false discovery rate (FDR) or false nondiscovery rate (FNR) as a type I error and some test statistics. In this article, we discuss Bonferroni (1960), Holm (1979), Benjamini and Hochberg (1995) and Benjamini and Yekutieli (2001) procedures based on T statistics, modified T statistics or local-pooled-error (LPE) statistics. We also consider Sun and Cai (2007) procedure based on Z statistics. These procedures are compared in the simulation and applied to Arabidopsis microarray gene expression data to identify differentially expressed genes.

• The Korean Journal of Applied Statistics
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• v.32 no.1
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• pp.1-13
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• 2019

An adaptive seamless Phase II/III clinical trial design enables a reduction in the sample size (in comparison to a conventional design) that also shortens the clinical development time. It is also very effective in clinical trials since it can have higher statistical power than Phase III alone. In this study, we use extensive simulation studies to compare several multiple hypothesis testing methods that can help select the best doses in a Phase II study along with several methods to combine p-values of the Phase II and Phase III study.