• Journal of Korean Ophthalmic Optics Society
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• v.12 no.4
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• pp.29-35
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• 2007

This study was conducted to measure the central corneal thickness(CTT) changes associated with kinds of wearing contact lens. The CCT was measured using ultrasonic pachymeter in three hundred four subjects in their 20s and 30s. Although the CCT of Group 1 who had never worn any kinds of contact lens had no differences between left and right eye as well as between genders, the CCT tended to become thinner depending on the increment in refractive error. In Group 2 wearing only soft contact lens, the CCT was thinner depending on wearing period, and subjects wearing for more than 10 years had significantly thin CCT comparing with subjects wearing for less than 4 years. There was no significant difference in the CCT between Group 3 wearing only RGP lens and Group 2 for less than 4 years. Furthermore, when comparing the CCT between the Group 2 and Group 4 changing to RGP lens after wearing soft contact lens, there was no statistically significant change in the CCT. However, the CCT was significantly thinner in Group 5 changing to soft contact lens after wearing PMMA(polymethyl methacrylate) hard lens compared with Group 2.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.3
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• pp.7-15
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• 2009

Purpose: To investigate the corneal recovery after discontinuing orthokeratology (OK) lenses wear in children for long-term period. Methods: Among the OK lens wearers who wear over 8 months and showed successful refractive correction, 25 subjects were selected who want to discontinue the OK lenses. Uncorrected visual acuity, refractive correction, corneal curvature (Sim K), central corneal thickness and corneal eccentricity were measured during the OK lens wearing period and after discontinuation for 1 month. Results: Uncorrected visual acuity and corneal shape had remodeled significantly during the OK lens wear and recovered significantly during the first week of discontinuation. Uncorrected visual acuity and refractive correction had achieved full recovery 2 weeks after discontinuation of lens wear and were highly correlated with the changes in corneal thickness. But corneal shape recovered slowly, eccentricity had recovered fully after 1 month and corneal curvature and central thickness had not been achieved full recovery until 1 month after discontinuation. Conclusions: Recovery of after longterm use of OK lens is rapid for refractive change, but slow for corneal curvature and central thickness that to refit the contact lenses, practitioners need patience.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.111-120
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• 2014

Purpose: This study was to investigate changes in the thickness of cornea, curvature of cornea, and aberration depending on the water contents, materials, and refractive power of contact lens. Methods: The differences in the corneal thickness between pre- and post-wearing the lenses were compared using 5 kinds of lenses. The changes in the corneal thickness, the curvatures of the anterior and posterior cornea, and high order aberration (HOA) before and after wearing the lenses were investigated at the center of the cornea, and the different distance and the direction away from the center of the cornea. For the equipments of measurement, ORB ScanII (Bausch & Lomb Inc, ver 3.14) was used to measure the corneal topography and thickness, and Zywave (Bausch & Lomb Inc, ver 5.20) was used to analyze the high order aberration. Results: Five (S1, S2, S3, T1, T2) of the lens was used for this study, excluding the lens T2 lens has four lenses and the thickness of the corneal shape, but the impact is minimal. In the case of the hydrogel soft contact lenses (T2 lens) with low oxygen permeability, the corneal thickness showed distinct increasing patterns. The high order aberration and coma aberration were most changed in the silicon hydrogel toric lens, while the depth of anterior was most changed in the hydrogel toric lens. Conclusion: Among the 5 kinds of contact lenses with different water contents, materials, and refractive power used for this study, the corneal shape change was small for the lenses with an oxygen permeability (Dk) of more than 28, and the largest for the lenses with a very low oxygen permeability.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.1
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• pp.41-50
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• 2011

Purpose: The present study was conducted to compare the centration of RGP lens on cornea when lens was fitted based on keratometric astigmatisms measured by keratometer and the lens centration when fitted by corneal topography. Methods: Thirty eight eyes of 19 male and female in their twenties were applied RGP lens with 9.9 mm of diameter by the keratometric astigmatisms classified by the measurement with a keratometer. Then, lens centrations were estimated using high speed camera and compared with the lens centration when fitted by total keratometric astigmatism using corneal topography. The relationship of the steepest location of cornea and lens centration was further compared. Results: With the rule astigmatism, lens centration was not changed even with the difference in central and total keratometric astigmatisms. When the relationship of the steepest part of cornea measured by corneal topography and lens centration was analyzed, the lens centration in vertical direction was exactly correlated with the steepest part of cornea in 52.3% of subjects. In the case of non-correlation, the steepest part of cornea was mostly upper part of cornea, however, lens centration was located on lower part of cornea. The lens centration in horizontal direction was exactly correlated with the steepest region of cornea in 65.6% of subjects. In non-correlated case, the difference in cornea curvatures between the steepest and the flattest parts was smaller than 0.05 mm in 76.9% of subjects. Conclusions: From these results, we conclude that corneal topographic patterns may more contribute the centration of RGP lens on cornea than the difference in central and total keratometric astigmatisms.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.4
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• pp.65-73
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• 2008

Purpose: The purpose of this study is to investigate the effect of age in the response to long-term overnight orthokeratology (OK) lens wearing. Methods: Among volunteers, ninety-five healthy subjects who had no eye diseases and could wear OK contact lens at least for 8 hours every day were divided into three groups children, youngsters and young adults. Unaided logMAR visual acuity, refractive error, apical corneal radius, corneal asphericity and central corneal thickness were measured with different period; before and after one day, one week, two weeks, one month, three months and six months of OK lens wear. Paired student t-test, ANOVA analysis and Pearson correlation were used with a critical p value of 0.05 for statistical analysis. Results: All groups showed statistically significant (p<0.001) improvement in unaided visual acuity, a trend for flattening in the apical corneal radius, decrease in central corneal thickness and less prolate after OK lens wear. The child group showed significantly rapid change (p<0.001) in visual acuity, and apical corneal radius showed that they reached the targeted refractive change earlier compared with youngster and adult groups. The visual effect of OK lens was significantly related with the change in central corneal thickness after long-term OK lens wear, especially in child and youngster group, and central corneal thickness were highly correlated with the targeted refractive change. Conclusions: Visual acuity change is statistically correlated with the central corneal thickness change, which is highly correlated with targeted refractive change in the long-term orthokeratology and younger lens wearers showed a rapid response to OK lens wear, suggesting a reduced epithelial response with increasing age. The results found this study extends our understanding and development in the long-term orthokeratology.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.151-156
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• 2015

Purpose: This study has been compared the degree of corneal edema arising from the material of the lens after wearing the recommended wearing time for the contact lens. Methods: For the study, 43 adults of 77 eyes who did not use drugs and have not any disease participated. Three types of lenses including narafilcon A, HEMA, and silicone hydrogel material regular replaceable lenses were used. Central corneal thickness was measured before and after 8 hours from wearing lenses using Pentacam. The degree of corneal edema was determined by the difference before and after wearing. Results: The average corneal edema of narafilcon A, HEMA material lens, and silicone hydrogel material regular replaceable lens were $2.36{\pm}6.15{\mu}m(Mean{\pm}SD)$, $23.61{\pm}10.71{\mu}m$, $18.25{\pm}8.64{\mu}m$, respectively. The central corneal thickness after wearing narafilcon A was not statistically significant with the central corneal thickness before wearing the lens. Central corneal thickness before and after wearing HEMA material lens and silicone hydrogel material regular replaceable lens were statistically significant. Conclusions: The amount of corneal edema induced by silicone hydrogel material regular replaceable lens was no statistically significant difference to the amount of corneal edema induced by HEMA material lens, but there was significant difference to narafilcon A. Therefore, it is judged to be careful not to exceed the recommended wearing time depending on the composition of the contact lens material.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.4
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• pp.439-444
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• 2011

Purpose: To represent the shape of toric corea in the elliptical function for the determination of curvature distribution and lacrimal thickness between cornea and contact lens when the lens is fitted. Methods: Topography measurements of corneal curvature and curvature equation derived from the assumed elliptical function were evaluated using the Excel program which included the necessary equation derived. Results: Mathematical expressions for the cornea whose ribbon shaped-topography image, in which the center does not coincide with the corneal apex, can be determined. Conclusions: For the application where the higher accuracy on the cornea is not required, such as higher order aberration, the cornea cal be expressed in the simple elliptical function.

• Journal of Korean Ophthalmic Optics Society
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• v.9 no.2
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• pp.281-290
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• 2004

The purpose of this study is to investigate the correlation between the central corneal thickness and peripheral one, and the changing aspect of corneal thickness by the refractive error through the measure of central corneal thickness and peripheral one in myopic eyes. For this study, the central thickness and the peripheral one of the 198 eyes of 99 normal subjects was measured by Orbscan Topography System(Orbtex, Inc. USA). The latter was measured in each 2mm point distance of superior, inferior, nasal and temporal from the center of left & right eye. And the revealed results was analyzed according to sex, age, left & right eyes, and refractive error of the subjects. The mean central corneal thickness of the whole subjects was shown as $530.12{\pm}43.18{\mu}m$, and the mean peripheral ones were as follows : superior(SCT) $591.91{\pm}36.88{\mu}m$, inferior(ICT) $561.04{\pm}41.82{\mu}m$, nasal(NCT) $584.23{\pm}41.97{\mu}m$ and temporal(TCT) $567.35{\pm}43.25{\mu}m$. From this, we can see that the mean central corneal thickness and the peripheral ones show significantly difference, but there is no statistically Significant difference in the corneal thickness according to refractive error, age, sex, and left & right.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.1
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• pp.27-35
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• 2012

Purpose: The present study was conducted to compare any difference caused by pigmentation in the centrations and movement patterns on the cornea between circle and soft contact lens with identical material and parameters during lens wearing. Methods: Soft and circle contact lenses with identical material and parameters were applied to twenty eyes with normal tear volume for 3 hrs a day during a total of 5 days and then their lens centrations, the moving distances and rotations by repeat blinking were compared. Results: The lens centration beyond the fitting criteria was shown in initial wears of both soft contact lens and circle contact lens. However, the centration of soft contact lens was changed to the pupil center for being suitable to the fitting criteria with longer wearing time. On the other hand, the decentration of circle contact lens in the horizontal direction was still presented even with longer wearing time. The moving distances of soft contact lens and circle contact lens decreased with the expand of lens wearing but were not significantly different between total wearing period and daily wearing time. The rotation of circle contact lens by repeat blinking was significantly different from that of soft contact lens even when the wearing period was extended. Conclusions: We revealed that the lens centration and movement of circle contact lens on cornea were different from those of regular soft contact lens resulting in bigger difference with the expand of wearing period in the study.

• Journal of The Korean Ophthalmological Society
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• v.59 no.11
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• pp.1049-1055
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• 2018

Purpose: To investigate the factors associated with glaucoma in patients with pseudoexfoliation syndrome by comparing features of the anterior segments and ocular biometry according to the presence or absence of open-angle glaucoma in pseudoexfoliation syndrome. Methods: We analyzed 96 patients (115 eyes) diagnosed as having pseudoexfoliation syndrome in this study. The patients were divided into two groups of simple pseudoexfoliation syndrome (64 patients, 76 eyes) and pseudoexfoliation glaucoma (32 patients, 39 eyes). We compared the age, sex, underlying disease, location of pseudoexfoliative material, iris change, degree of nuclear cataract, pupil dilatation, corneal endothelial cell counts, central corneal thickness, anterior chamber depth, axial length, corneal curvature, and intraocular pressure (IOP). Results: There were no significant differences between the two groups in terms of age (p = 0.694), sex (p = 0.161), diabetes (p = 0.440), hypertension (p = 0.238), pseudoexfoliative material observed in anterior capsule (p = 0.700), pupillary margin (p = 0.210), iris depigmentation (p = 0.526), pupillary ruff loss (p = 0.708), degree of nuclear cataract (p = 0.617), pupil dilatation (p = 0.526), central corneal thickness (p = 0.097), anterior chamber depth (p = 0.283), axial length (p = 0.095), or horizontal and vertical corneal curvature (p = 0.066 and 0.306, respectively). In pseudoexfoliation glaucoma, significantly higher IOP (p = 0.026), a high frequency of membrane formation (p = 0.047), and decreased corneal endothelial cell counts (p = 0.048) were observed. Conclusions: Pseudoexfoliation syndrome with open-angle glaucoma was shown to be associated with high IOP, decreased corneal endothelial cell counts, and a high frequency of membrane formation. Therefore, when such changes are observed in pseudoexfoliation syndrome patients, a higher risk of open-angle glaucoma should be recognized, and careful attentionis required accordingly.