• The Korean Journal of Physiology and Pharmacology
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• 제11권1호
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• pp.21-30
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• 2007

The present study was designed to establish comparatively the inhibitory effects of cilnidipine(CNP), nifedipine(NIF), and $\omega$-conotoxin GVIA(CTX) on the release of CA evoked by cholinergic stimulation and membrane depolarization from the isolated perfused model of the rat adrenal medulla. CNP(3 ${\mu}M$), NIF(3 ${\mu}M$), and CTX(3 ${\mu}M$) perfused into an adrenal vein for 60 min produced greatly inhibition in CA secretory responses evoked by ACh($5.32{\times}10^{-3}M$), DMPP($10^{-4}M$ for 2 min), McN-A-343($10^{-4}M$ for 2 min), high $K^+(5.6{\times}10^{-2}M)$, Bay-K-8644($10^{-5}M$), and cyclopiazonic acid($10^{-5}M$), respectively. For the CA release evoked by ACh and Bay-K-8644, the following rank order of potency was obtained: CNP>NIF>CTX. The rank order for the CA release evoked by McN-A-343 and cyclopiazonic acid was CNP>NIF>CTX. Also, the rank orders for high $K^+$ and for DMPP were NIF>CTX>CNP and NIF>CNP>CTX, respectively. Taken together, these results demonstrate that all voltage-dependent $Ca^{2+}$ channels(VDCCs) blockers of cilnidipine, nifedipine, and $\omega$-conotoxin GVIA inhibit greatly the CA release evoked by stimulation of cholinergic(both nicotinic and muscarinic) receptors and the membrane depolarization without affecting the basal release from the isolated perfused rat adrenal gland. It seems likely that the inhibitory effects of cilnidipine, nifedipine, and $\omega$-conotoxin GVIA are mediated by the blockade of both L- and N-type, L-type only, and N-type only VDCCs located on the rat adrenomedullary chromaffin cells, respectively, which are relevant to $Ca^{2+}$ mobilization. It is also suggested that N-type VDCCs play an important role in the rat adrenomedullary CA secretion, in addition to L-type VDCCs.

• 대한수학회논문집
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• 제33권3호
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• pp.1039-1048
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• 2018

In this paper we study the dynamics of a general ${\omega}-periodic$ model. Necessary and sufficient conditions for the global stability of zero steady state of the model are given. The conditions under which there exists a unique periodic solutions to the model are determined. We also show that the unique periodic solution is the global attractor of all other positive solutions. Some applications to mathematical models for cancer and tumor growth are given.

• 한국전산구조공학회논문집
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• 제30권1호
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• pp.47-53
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• 2017

1차원 등엔트로피 모델과 통합된 경계층 적분법은 초음속 노즐의 설계과정에서 내열재 표면의 열전달을 예측하는데 효과적으로 사용되고 있지만 노즐 목과 같이 2차원 효과와 경계층과 노즐 코어유동의 상호작용이 발생하는 지점에서는 경계층 외부유동 해석의 부정확성으로 해석의 정확도가 감소한다. 따라서 본 연구에서는 경계층 적분법을 이용한 열전달 예측의 정확도를 향상시키기 위해 CFD를 이용하여 2차원 효과와 노즐 코어유동의 상호작용이 고려된 경계층 외부유동 조건을 도출하고 이를 경계조건으로 하는 해석기법을 개발하였다. 오일러 모델과 SST $k-{\omega}$ 모델을 CFD로 해석하여 경계조건으로 적용했으며 계산방법을 검증하기 위해 선행문헌의 실험노즐에 대해 해석을 수행하였다. 계산 결과 CFD를 통해 경계층 외부유동 조건을 도출한 해석에서 노즐 열전달의 정확도가 향상되는 것을 확인하였으며 특히 노즐 목 후방과 팽창부에서의 차이가 크게 나타났다. SST $k-{\omega}$모델로 도출된 계산결과는 1차원 등엔트로피 모델과 비교 시 팽창부에서 실험결과와의 오차가 16% 감소하였다. 본 연구에서 개발된 해석기법은 향후 로켓노즐의 내열설계에 유용하게 사용될 것으로 평가된다.

• 한국진공학회지
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• 제6권S1호
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• pp.43-46
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• 1997

High resolution x-ray diffraction and two dimensional triple axis mapping were used to characterize a group of GaN layers of about 1.1$\mu$m grown by direct current plasma molecular beam epitaxy technique on 6H-SiC(0001). A FWHM of 11.9 arcmins for an $\omega$ scan and 1.2 arcmins for an $\omega$/2$\theta$ scan were observed. A careful study of the rocking curves showed there were some large mosaics in the GaN layer and a tilt of $0.029^{\circ}$ between the GaN layer and the SIC substrate was detected. The two dimensional triple axis mapping showed that the GaN mosaica were disoriented in the (0001) plane but rather uniformed in direction perpendicular to the plane. A mosaics were disoriented in the (0001) plane but rather uniformed in direction perpendicular to the plane. A mosaic model was deduced to explain the phenomenon and the dislocation density was estimated to be about~$10^9\;\textrm{cm}^{-2}$ acc ding to the model.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2011년도 제37회 추계학술대회논문집
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• pp.321-324
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• 2011

지상연소시험용 소형 액체로켓엔진 초음속 노즐의 성능해석을 위하여 노즐내 유동특성 및 플룸 구조를 $k-{\omega}$ SST모델을 사용한 Reynolds-averaged Navier-Stokes 방정식으로 해석하였다. 해석기법의 검증을 위하여 2차원 축소-확대 노즐 초음속 유동의 해석값과 실험치를 비교하고, 검증된 기법으로 2차원 축대칭 노즐의 성능해석을 수행하였다. 그 결과 노즐 내부에 유동박리 및 역류현상의 발생이 확인되었으며, 이 해석결과는 소형 액체로켓엔진 노즐 최적설계에의 기초자료로 제시되었다.

• Asian Journal of Atmospheric Environment
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• 제11권3호
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• pp.153-164
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• 2017

Odor dispersion around a cubic building from rooftop odor emissions was investigated using computational fluid dynamics (CFD). The Shear Stress Transport (here after SST) $k-{\omega}$ model in FLUENT CFD code was used to simulate the flow and odor dispersion around a cubic building. The CFD simulations were performed for three different configurations of cubic buildings comprised of one building, two buildings or three buildings. Five test emission rates were assumed as 1000 OU/s, 2000 OU/s, 3000 OU/s, 4000 OU/s and 5000 OU/s, respectively. Experimental data from wind tunnels obtained by previous studies are used to validate the numerical result of an isolated cubic building. The simulated flow and concentration results of neutral stability condition were compared with the wind tunnel experiments. The profile of streamline velocity and concentration simulation results show a reasonable level of agreement with wind tunnel data. In case of a two-building configuration, the result of emission rate 1000 OU/s illustrates the same plume behavior as a one-building configuration. However, the plume tends to the cover rooftop surface and windward facet of a downstream building as the emission rate increases. In case of a three-building configuration, low emission rates (<4000 OU/s) form a similar plume zone to that of a two-building configuration. However, the addition of a third building, with an emission rate of 5000 OU/s, creates a much greater odorous plume zone on the surface of second building in comparison with a two-building configuration.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 1998년도 추계 학술대회논문집
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• pp.90-95
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• 1998

The two-dimensional incompressible and compressible Navier-Stokes codes are developed for the computation of the viscous turbulent flow over high-lift airfoils. Incompressible code using pseudo-compressibility and dual-time stepping method involves a conventional upwind differencing scheme for the convective terms and LU-SGS scheme for time integration. Compressible code also adopts an FDS scheme and LU-SGS scheme. Several two-equation turbulence models (the standard $k-{\varepsilon}$ model, the $k-{\omega}$ model. and $k-{\omega}$ SST model) are evaluated by computing the flow over single and multi-element airfoils. The compressible and incompressible codes are validated by computing the flow around the transonic RAE2822 airfoil and the NACA4412 airfoil, respectively. Both the results show a good agreement with experimental surface pressure coefficients and velocity profiles in the boundary layers. Also, the GA(W)-1 single airfoil and the NLR7301 airfoil with a flap are computed using the two-equation turbulence models. The grid systems around two- and three-element airfoil are efficiently generated using Chimera grid scheme, one of the overlapping grid generation methods.

• 대한기계학회논문집B
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• 제25권10호
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• pp.1384-1391
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• 2001

Three-dimensional flow analysis is implemented to investigate the flow through transonic axial-flow compressor rotor(NASA R67) and to evaluate the performances of Abid's low-Reynolds-number k-$\omega$ and Baldwin-Lomax turbulence models. A finite volume method is used fur spatial discretization. The equations are solved implicitly in time by the use of approximate factorization. The upwind difference scheme is used for inviscid terms and viscous terms are approximated with central difference. The flux-difference-splitting method of Roe is used to obtain fluxes at the cell faces. Numerical analysis is performed near peak efficiency and near stall. The results are compared with the experimental data for NASA R67 rotor. Blade-to-Blade Mach number distributions are compared to confirm the accuracy of the code. From the results, it is concluded that Abid'k-$\omega$ model is better for the calculation of flow rate and efficiency than Baldwin-Lomax model. But, the predictions for Mach number and shock structure are almost the same.

• Journal of the Korean Wood Science and Technology
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• 제12권2호
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• pp.27-34
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• 1984

In order to investigate the acidic chlorinated compounds in pulp bleaching spent liquor, the lignin model compounds, coniferyl alcohol(mp $74^{\circ}C$), ${\omega}$-(2-methoxyphenoxy)-acetoguaiacone(mp $93^{\circ}C$) and dehydrodiisoeugenol(mp $133^{\circ}C$), were synthesized and chlorinated by chlorine in glacial acetic acid. From the chlorinated products, the following chlorine-containing aromatic compounds were identified by TLC. In coniferyl alcohol the chlorine-substituted compounds at 4-, 5-and 4,5-position of aromatic nucleus were identified and in ${\beta}$-0-4 type the compounds substituted chlorine for alkyl group and/or hydrogen at land 1,4-position of aromatic nucleus expected to be formed by electrophilic displacement from ${\omega}$-(2-methoxyphenoxy)-acetoguaiacone were not identified but the chlorine-substituted compounds at 4-, 5-, 6- and 5,6-position of aromatic nucleus were identified.

• 한국산업융합학회 논문집
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• 제2권2호
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• pp.91-102
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• 1999

The paper describes a robust adaptive control algorithm for induction motor drive without speed sensor at low speed range. The control algorithm use only current sensors in a space vector pulse width modulation within loop control with rotor speed estimation and voltage source inverter. On-line rotor speed estimation is based on utilizing parallel model reference adaptive control system. MRAC of the modified flux model for flux and rotor speed estimator uses dual-adaptation mechanism, ${\omega}_r$ and ${\omega}_e$ scheme. The estimated flux components in the model can be compensated from the effects of offset errors on pure integrals. It can be compensated to the parameter variations and torque fluctuation with speed estimation in less then 10 rad/sec. In a simulation, the proposed induction motor control algorithm without speed sensor at very low speed range are shown to operate very well in spite of variable rotor time constant and fluctuating load without change the controller parameters. The suggested control strategy and estimation method have been validated by simulation study, and it proposed the designed system for the implementation using TI320C31 DSP/ASIC controller.