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검색결과 130건 처리시간 0.023초

Development of a Spirulina Extract/Alginate-Imbedded PCL Nanofibrous Cosmetic Patch

  • Byeon, Seon Yeong;Cho, Myung Kwon;Shim, Kyou Hee;Kim, Hye Jin;Song, Hyeon Gi;Shin, Hwa Sung
    • Journal of Microbiology and Biotechnology
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    • 제27권9호
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    • pp.1657-1663
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    • 2017
  • Cosmetic patches have recently been developed as skin products for personal care owing to rapid advances in the technology of delivery of active ingredients, moisture, and adhesiveness to skin. Alginate and Spirulina are typical marine resources used in cosmetic products. This research involved the development of a Spirulina extract-impregnated alginate nanofiber cosmetic patch supported by a polycaprolactone (PCL) nanofiber cover (Spi/Alg-PCL NF patch). In addition to the ability of alginate to affect moisture and adhesiveness to skin, the impregnation of Spirulina extract strengthened those abilities as well as its own bioactive effectiveness. All fabrication processing steps were undertaken in aqueous solution. The three components (alginate, Spirulina extract, and PCL) had no detected cytotoxicity in human keratinocyte cell-based examination. In addition, wetting the pre-dried patch on the skin resulted in the Spirulina extract being released within 30 min. The results indicate the excellence of the Spi/Alg-PCL NF patch as a skin-care cosmetic device.

먹거리를 활용한 유아 수학교육 프로그램이 만 4세 유아의 수학능력에 미치는 효과 (The Effects of Mathematics Education Program Utilizing Food on 4-Year-Old Children's Mathematical Ability)

  • 오미라;민하영;조우미
    • 한국보육지원학회지
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    • 제15권3호
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    • pp.115-133
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    • 2019
  • Objective: The purpose of the study was to develop a mathematics education program utilizing food to improve the mathematical abilities of 4-year-olds and to analyze the effects of this program on 4-years-olds' mathematical concepts (number and operation, algebra, geometry, measurement, data analysis, and probability). Methods: The study selected 30 4-year-olds from two daycare centers located in K city. The experimental group (N=15) participated in the mathematics education program utilizing food, 10 times for five weeks, while the comparative group (N=15) participated in the seasonal mathematics education program based on the Nuri Curriculum. The activities of this intervention program were designed to cover all domains of Mathematical Exploratory areas in the Nuri Curriculum. For data processing and analysis, pre-test and post-test score differences between the two groups were analyzed through MANCOVA. Results: The experimental group had significantly higher scores on five mathematical concepts compared with the control group. A mathematics education program utilizing food had the positive effect of improving 4-year-olds' mathematical ability. Conclusion/Implications: Mathematic education programs utilizing food are recommended as necessary pedagogical data to develop the mathematical abilities of children in education centers, families, or relating to parenting education.

2018 심방세동 카테터 절제술 대한민국 진료지침: Part II

  • 유희태;정동섭;박희남;박형섭;김주연;김준;이정명;김기훈;윤남식;노승영;오용석;조영진;심재민
    • International Journal of Arrhythmia
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    • 제19권3호
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    • pp.235-284
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    • 2018
  • In this part the writing group will cover strategies, techniques, and endpoints of atrial fibrillation (AF) ablation. Prior to all, electrical isolation of the pulmonary veins is recommended during all AF ablation procedures. In addition, techniques to be used for ablation of persistent and long-standing persistent AF, adjunctive ablation strategies, nonablative strategies to improve outcomes of AF ablation, and endpoints for ablation of paroxysmal, persistent, and long-standing persistent AF will be reviewed. Currently many technologies and tools are employed for AF ablation procedures. Radiofrequency energy, cryoablation, and other energy sources and tools are in various stages of development and/or clinical investigation. Finally, anticoagulation strategies pre-, during, and postcatheter ablation of AF and technical aspects of ablation to maximize safety are discussed in this section.

A Remote Sensing Scene Classification Model Based on EfficientNetV2L Deep Neural Networks

  • Aljabri, Atif A.;Alshanqiti, Abdullah;Alkhodre, Ahmad B.;Alzahem, Ayyub;Hagag, Ahmed
    • International Journal of Computer Science & Network Security
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    • 제22권10호
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    • pp.406-412
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    • 2022
  • Scene classification of very high-resolution (VHR) imagery can attribute semantics to land cover in a variety of domains. Real-world application requirements have not been addressed by conventional techniques for remote sensing image classification. Recent research has demonstrated that deep convolutional neural networks (CNNs) are effective at extracting features due to their strong feature extraction capabilities. In order to improve classification performance, these approaches rely primarily on semantic information. Since the abstract and global semantic information makes it difficult for the network to correctly classify scene images with similar structures and high interclass similarity, it achieves a low classification accuracy. We propose a VHR remote sensing image classification model that uses extracts the global feature from the original VHR image using an EfficientNet-V2L CNN pre-trained to detect similar classes. The image is then classified using a multilayer perceptron (MLP). This method was evaluated using two benchmark remote sensing datasets: the 21-class UC Merced, and the 38-class PatternNet. As compared to other state-of-the-art models, the proposed model significantly improves performance.

동적 및 정적 물체 회피를 위한 정밀 도로지도 기반 지역 경로 계획 (High-Definition Map-based Local Path Planning for Dynamic and Static Obstacle Avoidance)

  • 정의곤;송원호;명현
    • 로봇학회논문지
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    • 제16권2호
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    • pp.112-121
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    • 2021
  • Unlike a typical small-sized robot navigating in a free space, an autonomous vehicle has to travel in a designated road which has lanes to follow and traffic rules to obey. High-Definition (HD) maps, which include road markings, traffic signs, and traffic lights with high location accuracy, can help an autonomous vehicle avoid the need to detect such challenging road surroundings. With space constraints and a pre-built HD map, a new type of path planning algorithm can be conceived as a substitute for conventional grid-based path planning algorithms, which require substantial planning time to cover large-scale free space. In this paper, we propose an obstacle-avoiding, cost-based planning algorithm in a continuous space that aims to pursue a globally-planned path with the help of HD map information. Experimentally, the proposed algorithm is shown to outperform other state-of-the-art path planning algorithms in terms of computation complexity in a typical urban road setting, thereby achieving real-time performance and safe avoidance of obstacles.

대한민국 수용자 의료처우의 실질적 개선 (Substantial Improvement of Medical Care for Detainees in Republic of Korea)

  • 홍사민
    • 보건행정학회지
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    • 제33권3호
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    • pp.370-375
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    • 2023
  • The responsibility to ensure the health rights of detainees, particularly their medical rights, fundamentally lies with the state in all nations. However, in the correctional facilities of the Republic of Korea, these rights are currently not adequately safeguarded. Numerous detainees express dissatisfaction with the medical services provided and show a preference for voluntary external treatment. However, barriers such as prolonged application processes for external treatment and the requirement for detainees to cover their medical expenses present significant challenges. Therefore, the National Human Rights Commission of Korea has advocated for an increased medical budget in correctional facilities and a bolstered professional medical workforce to improve the medical care of detainees. Recommendations for improvements include: (1) establishing dedicated correctional hospitals for detainees, (2) setting up specialized correctional wards, (3) collaborating with military hospitals, (4) launching mobile medical buses for diverse specialties, (5) enhancing collaboration with public and private medical institutions, (6) increasing compensation for partnering external medical institutions, (7) improving the working conditions of medical officers, (8) safeguarding the defense rights of medical staff, (9) improving the working conditions of public health doctors from the Ministry of Justice in correctional facilities, and (10) pre-assigning public health specialists and military doctors to correctional facilities. By implementing these measures, it is anticipated that the quality of medical services in the Republic of Korea's correctional facilities will improve, reducing the demand for external treatments among detainees and ensuring their health and medical rights are realistically upheld.

Studies on seismic performance of the new section steel beam-wall connection joint

  • Weicheng Su;Jian Liu;Changjiang Liu;Chiyu Luo;Weihua Ye;Yaojun Deng
    • Structural Engineering and Mechanics
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    • 제88권5호
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    • pp.501-519
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    • 2023
  • This paper introduces a new hybrid structural connection joint that combines shear walls with section steel beams, fundamentally resolving the construction complexity issue of requiring pre-embedded connectors in the connection between shear walls and steel beams. Initially, a quasi-static loading scheme with load-deformation dual control was employed to conduct low-cycle repeated loading experiments on five new connection joints. Data was acquired using displacement and strain gauges to compare the energy dissipation coefficients of each specimen. The destruction process of the new connection joints was meticulously observed and recorded, delineating it into three stages. Hysteresis curves and skeleton curves of the joint specimens were plotted based on experimental results, summarizing the energy dissipation performance of the joints. It's noteworthy that the addition of shear walls led to an approximate 17% increase in the energy dissipation coefficient. The energy dissipation coefficients of dog-bone-shaped connection joints with shear walls and cover plates reached 2.043 and 2.059, respectively, exhibiting the most comprehensive hysteresis curves. Additionally, the impact of laminated steel plates covering composite concrete floors on the stiffness of semi-rigid joint ends under excessive stretching should not be disregarded. A comparison with finite element analysis results yielded an error of merely 2.2%, offering substantial evidence for the wide-ranging application prospects of this innovative joint in seismic performance.

선박 선체에 대한 수리작업 공정분석에 관한 연구 (A Study on Repair Process Analysis of Ship Hul Part)

  • 전창수
    • 한국산업융합학회 논문집
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    • 제26권6_3호
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    • pp.1305-1314
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    • 2023
  • The global ship repair and modification market is expected to grow up to approximately $ 30 billion by 2025. Korea's shipbuilding industry is leading the world grounded on its international competitiveness in design and production technology. The reality, however, is that the ship repair and modification industry is centered on Gyeongnam, and there are only two to three ship repair workplaces that can repair large ships. Therefore, domestic ship repair companies target small and medium-sized ships mainly. This is because there are few workplaces equipped with a large dock in which large ships like LNG ships can be inspected regularly or repaired, complaints are severe for environmental problems, and related environmental regulations are so strict that it is very hard to obtain government approval for the extension of ship repair and modification workplaces or the opening of new shipbuilding sites. Besides, on account of the workers' high wages, few experts related, and higher ship repair price compared to that of Southeast Asia, most of the volume of repairing large ships including domestic LNG ships is being lost to Southeast Asian or Chinese markets. In this study, the work process and pre-work preparation process for ship hull (winch, windlass, hatch cover, ramp door, cargo gear, anchor chain) repair were analyzed and presented to foster domestic ship repair experts and revitalize related industries.

비탄성 지진 해석을 통한 박스 터널의 손상 상태 및 손상 지수 규명 (Identification of damage states and damge indices of single box tunnel from inelastic seismic analysis)

  • 박두희;이태형;김한섭;박정선
    • 한국터널지하공간학회 논문집
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    • 제18권2호
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    • pp.119-128
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    • 2016
  • 성능기반 설계에서 구조물의 안정성은 손상 상태와 이를 수치화한 손상 지수에 의해 평가한다. 지상 구조물에 대해서는 이들이 비교적 명확하게 정의되어 있으나 지중 구조물에 대한 연구 수행 사례는 매우 제한적이다. 본 연구에서는 국내 지하철 시스템에 널리 사용되는 박스형 개착식 터널에 작용하는 지진하중에 의한 손상 상태와 손상 지수를 일련의 비탄성 프레임 해석을 통하여 규명하였다. 터널의 3 단계 손상 상태는 구조물에 발생한 소성 힌지의 수에 의해 정의하였다. 손상 지수는 터널 구조 부재의 탄성 모멘트와 항복 모멘트의 비로 정의하여 탄성 해석만으로도 비탄성 거동과 파괴 메커니즘의 모사가 가능하도록 하였다. 또한 손상 지수를 자유장 전단 변형률의 함수로도 제시하였다. 전단 변형률은 1 차원 지반응답해석으로 쉽게 계산할 수 있으므로 이를 이용하여 간편하게 박스형 터널의 초기 내진 안정성 평가가 가능할 것으로 판단된다. 보다 일반적이고 보편적인 적용성 확보를 위해서는 추후 포괄적인 해석을 수행하여 다양한 형태의 터널과 지반에서의 전단 변형률 분포와 불확실성에 대한 연구가 진행되어야 할 것이다. 본 연구에서 제시된 터널 내진설계를 위한 손상 상태, 손상 지수, 그리고 전단파 속도 및 전단변형률 간의 상호관계 플래트폼은 새로운 아이디어를 담고 있으며 추후 설계에 널리 활용될 수 있을 것으로 판단된다.

지반보강용 주입재의 성능향상을 위한 초음파 에너지의 활용 (Application of ultrasonic energy to enhance capability of soil improving material)

  • 문준호;;정강복;김영욱
    • 한국터널지하공간학회 논문집
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    • 제19권4호
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    • pp.567-576
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    • 2017
  • 본 연구에서는 지반보강용 시멘트-페이스트에 초음파를 조사하여 온도변화, 점도, 일축압축강도, 육안관측 시험을 통해 초음파가 시멘트-페이스트에 어떠한 물리적 특성을 변화시키는지에 대하여 고찰하였다. 실험에 사용된 w/c는 50~100%까지 다양하게 진행하였으며, 그라우트재의 온도변화는 ${\pm}2^{\circ}C$내에서 범위를 벗어나지 않도록 조절하여 실험을 진행하였다. 실험결과 온도변화는 초음파 조사시간에 비례하여 일정하게 증가하였고, 초음파를 조사한 지반보강용 시멘트-페이스트 점도는 최대 40%까지 감소하는 것으로 나타났다. 일축압축강도는 평균 30% 증가하였으며 육안관측시험에서도 초음파를 조사한 시멘트-페이스트의 단면이 공극이 많이 감소하는 양상을 보였다.