Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Development of a Spirulina Extract/Alginate-Imbedded PCL Nanofibrous Cosmetic Patch

  • Byeon, Seon Yeong (Department of Biological Engineering, Inha University) ;
  • Cho, Myung Kwon (Department of Biological Engineering, Inha University) ;
  • Shim, Kyou Hee (Department of Biological Engineering, Inha University) ;
  • Kim, Hye Jin (Department of Biological Engineering, Inha University) ;
  • Song, Hyeon Gi (Department of Biological Engineering, Inha University) ;
  • Shin, Hwa Sung (Department of Biological Engineering, Inha University)
  • Received : 2017.01.10
  • Accepted : 2017.07.10
  • Published : 2017.09.28
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Abstract

Cosmetic patches have recently been developed as skin products for personal care owing to rapid advances in the technology of delivery of active ingredients, moisture, and adhesiveness to skin. Alginate and Spirulina are typical marine resources used in cosmetic products. This research involved the development of a Spirulina extract-impregnated alginate nanofiber cosmetic patch supported by a polycaprolactone (PCL) nanofiber cover (Spi/Alg-PCL NF patch). In addition to the ability of alginate to affect moisture and adhesiveness to skin, the impregnation of Spirulina extract strengthened those abilities as well as its own bioactive effectiveness. All fabrication processing steps were undertaken in aqueous solution. The three components (alginate, Spirulina extract, and PCL) had no detected cytotoxicity in human keratinocyte cell-based examination. In addition, wetting the pre-dried patch on the skin resulted in the Spirulina extract being released within 30 min. The results indicate the excellence of the Spi/Alg-PCL NF patch as a skin-care cosmetic device.

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