• Fisheries and Aquatic Sciences
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• 제15권1호
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• pp.15-19
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• 2012

A new cyclic peptide (six-membered amino acid), gamakamide-E (L-Leu-L-Met (SO)-L-Me-Phe-L-Leu-D-Lys-L-Phe), was isolated as a strongly bitter tasting compound from cultured oysters, Crassostrea gigas. The molecular formula of $C_{43}H_{61}N_7O_8S$ was deduced from high resolution fast atom bombardment mass spectrometry (HR FAB-MS) ($[M+H]^+$ m/z 836.4356 ${\Delta}$= -2.4 mmu). Its unique structure including a hydantoin structure was firstly elucidated by nuclear magnetic resonance (NMR) analysis. Stereochemistries of constituent amino acids were determined by chiral high performanced liquid chromatography analysis of natural and synthesized peptides.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2002년도 춘계학술대회 논문집
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• pp.257-260
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• 2002

The impressions for odors are subjective and have individual differences. In this study, the Impressions of odors were investigated by covariance structure analysis. 46 subjects (men in their twenty) recorded their reactions to ten odorants by grading them on a seven-point scale in terms of twelve adjective pairs. Their reactions were quantified by using factor analysis and covariance structure analysis. The factors were extracted as "preference", "arousal" and "persistency". The subjects were classified into three groups according to the most suitable causal models (structural equation models). Each group had different causal relationship and different impression structure for odors. It was suggested that there is a possibility to evaluate the subjective impression of odor using covariance structure analysis.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 추계학술대회 논문집 학회본부 C
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• pp.735-736
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• 1998

Reduction of hot carrier degradation in MOS devices has been one of the most serious concerns for MOS-ULSIs. In this paper, three types of LDD structure for suppression of hot carrier degradation, such as spacer-induced degradation and decrease of performance due to increase of series resistance will be investigated. LDD-nMOSFETs used in this study had three different drain structure. (1) conventional ${\underline{S}}urface$ type ${\underline{L}}DD$(SL), (2) ${\underline{B}}uried$ type ${\underline{L}}DD$(BL), (3) ${\underline{S}}urface$urface ${\underline{I}}mplantation$ type LDD(SI). As a result, the surface implantation type LDD structure showed that improved hot carrier lifetime to comparison with conventional surface and buried type LDD structure.

• 한국결정학회지
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• 제6권2호
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• pp.80-87
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• 1995

Tetrapropionyloxycalix[4]arene(C40H40O8)의 결정 및 분자를 X-선 회절법으로 연구하였다. 이 결정은 단사정계이고 공간군은 P21/n이다. 단위세포 길이는 a=13.921(3), b=13.552(2), c=19.840(5)Å이며, β=110.38(2)°, Z=4이다. 회절반점들의 세기는 흑연단색화 장치가 있는 Enraf-Nonius CAD-4 Diffractometer로 얻었으며, Mo-Kα X-선(λ=0.7107Å)을 사용하였다. 분자구조는 직접법으로 풀었으며 최소자승법으로 정밀화하였다. 최종 신뢰도 R값은 2514개의 회절반점에 대하여 0.06이었다. 본 Calixarene은 partial cone conformation을 이루고 있어 세 개의 phenyl group들과 나머지 한 개의 phenyl group사이에 서로 다른 배향을 가지고 있다. 세 개의 phenyl group들은 macrocycle로 된 cavity 바깥쪽을 향하여 배열되어 있다.

• 대한수학회지
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• 제45권3호
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• pp.597-609
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• 2008

In this paper, we will consider certain amalgamated free product structure in crossed product algebras. Let M be a von Neumann algebra acting on a Hilbert space Hand G, a group and let ${\alpha}$ : G${\rightarrow}$ AutM be an action of G on M, where AutM is the group of all automorphisms on M. Then the crossed product $\mathbb{M}=M{\times}{\alpha}$ G of M and G with respect to ${\alpha}$ is a von Neumann algebra acting on $H{\bigotimes}{\iota}^2(G)$, generated by M and $(u_g)_g{\in}G$, where $u_g$ is the unitary representation of g on ${\iota}^2(G)$. We show that $M{\times}{\alpha}(G_1\;*\;G_2)=(M\;{\times}{\alpha}\;G_1)\;*_M\;(M\;{\times}{\alpha}\;G_2)$. We compute moments and cumulants of operators in $\mathbb{M}$. By doing that, we can verify that there is a close relation between Group Freeness and Amalgamated Freeness under the crossed product. As an application, we can show that if $F_N$ is the free group with N-generators, then the crossed product algebra $L_M(F_n){\equiv}M\;{\times}{\alpha}\;F_n$ satisfies that $$L_M(F_n)=L_M(F_{{\kappa}1})\;*_M\;L_M(F_{{\kappa}2})$$, whenerver $n={\kappa}_1+{\kappa}_2\;for\;n,\;{\kappa}_1,\;{\kappa}_2{\in}\mathbb{N}$.

• Applied Biological Chemistry
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• 제35권5호
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• pp.382-388
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• 1992

N-치환 phenyl-5-chloro-1,3-dimethylpyrazole-4-carboxamide 45종을 합성, Rhizoctonia solani에 대한 50% 균사생육저해율$(EC_{50})$을 검정한 후 구조활성상관관계를 규명하기 위해 화합물의 소수성 파라메타인 log k', 치환기의 소수성 파라메타 ${\pi}$, 전자적 파라메타인 Hammett 치환상수 ${\sigma}$ 및 입체적 파라메타인 STERIMOL 상수 L을 사용하여 다중회귀식을 도출하였다(식(8)). 이 식에 의해 83%의 생리활성변화가 유의성있게 해석되었으며 활성에 영향을 미치는 가장 중요한 인자는 화합물의 체내흡수 및 작용점으로의 이행에 관여하는 log k'으로 밝혀졌고 그 밖에 phenyl고리의 2번위치와 3번위치 치환기의 장축을 표현하는 입체적 파라메타인 $L_3$과 $L_4$등도 활성을 지배하는 인자로 확인되었다.

• 대한수학회지
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• 제34권4호
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• pp.859-869
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• 1997

It is shown that for $A_{k, m}$ a k-homogeneous $C^*$-algebra over $S^{2n - 1} \times S^1$ such that no non-trivial matrix algebra can be factored out of $A_{k, m}$ and $A_{k, m} \otimes M_l(C)$ has a non-trivial bundle structure for any positive integer l, we construct an $A_{k, m^-} C(S^{2n - 1} \times S^1) \otimes M_k(C)$-equivalence bimodule to show that every k-homogeneous $C^*$-algebra over $S^{2n - 1} \times S^1)$. Moreover, we prove that the tensor product of the k-homogeneous $C^*$-algebra $A_{k, m}$ with a UHF-algebra of type $p^\infty$ has the tribial bundle structure if and only if the set of prime factors of k is a subset of the set of prime factors of pp.

• Parasites, Hosts and Diseases
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• 제62권3호
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• pp.330-341
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• 2024

The Trichinella spiralis novel cystatin (TsCstN) inhibits cathepsin L (CatL) activity and inflammation of macrophages during lipopolysaccharide (LPS) induction. To identify the protease inhibitory region, this study applied an in silico modeling approach to simulate truncation sites of TsCstN (Ts01), which created four truncated forms, including TsCstN^∆1-39 (Ts02), TsCstN^∆1-71 (Ts03), TsCstN^{∆1-20, ∆73-117} (Ts04), and TsCstN^{∆1-20, ∆42-117} (Ts05). The superimposition of these truncates modeled with AlphaFold Colab indicated that their structures were more akin to Ts01 than those modeled with I-TASSER. Moreover, Ts04 exhibited the closest resemblance to the structure of Ts01. The recombinant Ts01 (rTs01) and truncated proteins (rTs02, rTs03, and rTs04) were successfully expressed in a prokaryotic expression system while Ts05 was synthesized, with sizes of approximately 14, 12, 8, 10, and 2.5 kDa, respectively. When determining the inhibition of CatL activity, both rTs01 and rTs04 effectively reduced CatL activity in vitro. Thus, the combination of the α1 and L1 regions may be sufficient to inhibit CatL. This study provides comprehensive insights into TsCstN, particularly regarding its protein function and inhibitory domains against CatL.

• 한국자기공명학회논문지
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• 제12권2호
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• pp.65-73
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• 2008

HP1298 (Swiss-Prot ID ; P65108) is an 72-residue protein from Helicobacter pylori strain 26695. The function of HP1298 was identified as Translation initiation factor IF-l based on sequence homology, and HP1298 is included in IF-l family. Here, we report the sequence-specific backbone resonance assignments of HP1298. About 97% of all the $^{1}HN$, $^{15}N$, $^{13}C{\alpha}$, $^{13}C{\beta}$, and $^{13}CO$ resonances could be assigned unambiguously. We could predict the secondary structure of HP1298, by analyzing the deviation of the $^{13}C{\alpha}$ and $^{13}C{\beta}$ shemical shifts from their respective random coil values. Secondary structure prediction shows that HP1298 consists of six $\beta$-strands. This study is a prerequisite for determining the solution structure of HP1298 and investigating the structure-function relationship of HP1298. Assigned chemical shift can be used for the study on interaction between HP1298 and other Helicobacter pylori proteins.

• 한국정보과학회논문지:데이타베이스
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• 제33권1호
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• pp.12-31
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• 2006

n-gram 기반 역색인 구조는 언어 중립적이고 에러 허용적인 장점들로 인해 일부 아시아권 언어에 대한 정보 검색이나 단백질과 DNA의 sequence의 근사 문자열 매칭에 유용하게 사용되고 있다. 그러나, n-gram 기반의 역색인 구조는 색인의 크기가 크고 질의 처리 시간이 오래 걸린다는 단점들을 가지고 있다. 이에 본 논문에서는 n-gram 기반 역색인의 장점을 그대로 유지하면서 색인의 크기를 줄이고 질의 처리 성능을 향상시킨 2단계 n-gram 역색인(간단히 n-gram/2L 역색인이라 부른다)을 제안한다. n-gram/2L 역색인은 n-gram 기반 역색인에 존재하던 위치 정보의 중복을 제거한다. 이를 위해 문서로부터 길이 m의 m-subsequence들을 추출하고, 그 m-subsequence들로부터 n-gram을 추출하여 2단계로 역색인을 구성한다. 이러한 2단계 구성 방법은 이론적으로 의미 있는 다치 종속성이 존재하는 릴레이션을 정규화하여 중복을 제거하는 것과 동일하며, 이를 본문에서 정형적으로 증명한다. n-gram/2L 역색인은 데이타의 크기가 커질 수록 n-gram 역색인에 비해 색인 크기가 줄어들며 질의 처리 성능이 향상되고, 질의 문자열의 길이가 길어져도 질의 처리 시간이 거의 증가하지 않는 좋은 특성을 가진다. 1GByte 크기의 데이타에 대한 실험을 통하여, n-gram/2L 역색인은 n-gram 기반 역색인에 비해 최대 1.9${\~}$2.7배 더 작은 크기를 가지면서, 동시에 질의 처리 성능은 3${\~}$18 범위의 길이를 가지는 질의들에 대해 최대 13.1배 향상됨을 보였다.