• Title/Summary/Keyword: $k_La$

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Effects of Longanae Arillus Water Extract on Inflammatory Response and Cytokines in Mouse Macrophage Cells (용안육(龍眼肉) 물추출물이 대식세포의 염증반응과 Cytokine에 미치는 영향)

  • Kim, Mi-Rim;Lim, Eun-Mee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.27 no.2
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    • pp.1-11
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    • 2014
  • Objectives: The purpose of this study was to investigate the effects of Longanae Arillus water extract (LA) on the production of inflammatory mediators in RAW 264.7 cell. LA is used for forgetfulness, insomnia, palpitation symptoms in korean medicine. Methods: In order to evaluate cytotoxicity of LA, cell viability was measured. To investigate anti-inflammatory effects of LA in the lipopolysacharide (LPS)-induced RAW 264.7 cell, the concentration of nitric oxide (NO) and cytokines were measured. And when p-value is below 0.05, it is judged to have the significant difference statistically. Results: 1. LA showed no cytotoxicity. 2. LA inhibited significantly the production on NO at the concentration of 50 and $200{\mu}g/ml$. 3. LA inhibited significantly the production on interleukin (IL)-$1{\beta}$ at the concentration of 25, 50, 100 and $200{\mu}g/ml$. 4. LA inhibited significantly the production on tumor necrosis factor (TNF)-${\alpha}$ at the concentration of 50, 100 and $200{\mu}g/ml$. 5. LA inhibited significantly the production on lipopolysaccharide-induced chemokine (LIX) at the concentration of 25, 100 and $200{\mu}g/ml$. 6. LA inhibited significantly the production on regulated on activation normal T cell expressed and secreted (RANTES) at the concentration of $200{\mu}g/ml$. Conclusions: These results suggest that LA has anti-inflammatory effect.

Freshness of 'Fuji' Apples Packed Anti-fogging Agents Film (결로 방지 필름으로 포장한 '후지' 사과의 신선도)

  • Park, Hyung-Woo;Ryu, Na-Hee
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.19 no.1
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    • pp.29-33
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    • 2013
  • This study investigated the effect of films treated with anti-fogging (LA) agent on the freshness extension of 'Fuji' Apples. Preference, weight loss, total ascorbic acid, sugar content, acidity, change of gas composition in package were evaluated during storage at $15^{\circ}C$. After 150 days of storage, the weight loss of apples in control (L), LA was 1.0 to 1.1%. Total ascorbic acid content of apples in control after 150 days was 2.09 mg/100g F.W, that of apple in LA was 2.47 mg/100g F.W. The titratable acidity of apple in LA was lower than that in control, while soluble solids content of LA was higher than that in control after 150 days. Ethylene gas adsorbability in control package was 192.2 ppm and that in LA was 195.7 ppm. It was verified that LA treated with anti-fogging agent are few different compare to control, but commerdity on the display in market was considered higher than that of non-treated anti-fogging agent.

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Electical Transport Properties of La$_{1.6}$Ca$_{1.4}$Mn$_2$O$_{7.07}$ System (La$_{1.6}$Ca$_{1.4}$Mn$_2$O$_{7.07}$의 전기전도특성)

  • 정우환
    • Journal of the Korean Ceramic Society
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    • v.36 no.8
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    • pp.843-847
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    • 1999
  • The dc resistivity dc magnetization and thermopower of layered perovskite La1.6Ca1.4Mn2O7.07 have been studied. The ceramic sample of La1.6Ca1.4Mn2O7.07 undergoes the metal-insulator transition at 120K while a first-order phase transition from a ferromagnetic phase to a paramagnetic phae is observed at 260 K=TC This behavior is quite different from that of the well-known double exchange ferromagnets such as La1-xCaxMnO3 This phenomenon could be understood by considering the effects of the anisotropic double exchange interaction caused by two dimensional Mn-O-Mn networks in this materials. The dc magnetization between 120K and 250K is nearly constant and decreases rapidly with increasing temperature above 250K The measurements of dc resistivity and thermopower indicate that Zener polaron hopping conduction takes place above 260 K.

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The Effects of $La_2O_3$ on PTC characteristics of $BaTiO_3$ Ceramics ($BaTiO_3$ 세라믹스의 PTC특성에 미치는 $La_2O_3$의 영향)

  • Kim, H.K.;Yuk, J.H.;Park, K.S.;Jung, S.Y.;Kim, J.S.;Lee, D.C.
    • Proceedings of the KIEE Conference
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    • 1993.07b
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    • pp.1116-1118
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    • 1993
  • $({Ba}_{1-x}La_x)TiO_3,\;x=0{\sim}0.005$ specimens were fabricated by solid stste reaction method, and their PTC characteristics were examined. The gain growth is inhibited by La substitution, and it is confirmed that the specimens are crystallized at $900^{\circ}C$ from DTA analysis. The 0.003mol La substituded specimens show lowest resistivity and best PTC effects. Furthermore, the electrode sintered-specimens exhibite better PTC effects than no sintered-specimens.

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Optimization of Bioreactor Operation by Mass Transfer Coefficient (물질전달계수를 이용한 생물 반응기 운전 최적화)

  • Kim, Hyung-Soon
    • Journal of the Korean Society of Industry Convergence
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    • v.4 no.3
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    • pp.243-251
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    • 2001
  • The effects of various operating parameters(agitation speed, impeller type, antiform agents, impeller spacing etc.) on air-liquid mass transfer was characterized by volumetric mass transfer coefficient($k_La$). Also, the dual-impeller agitated systems are compared with single-impeller agitated systems with a special focus on its applications for bioreactors, $k_La$ was take over a range of 200~450 rpm of agitation speed, and 0.5~2.5 vvm of air flow rates, for four single impeller and impeller combinations consisting of four impeller types, namely rushton, pitched blade, scaba, intermig were tested. The rushton impeller showed the best $k_La$ as compared with other single impellers. The dual impeller system are found to be superior as compared to single impeller in all aspects, The best combination of the dual impeller was a intermig of axial flow type as an upper impeller and a rushton of radial flow type as a lower part. Also, the control of the DO level with the variation of agitation speed was more efficient than that with an increase in air flow rate. The addition of antiform dropped the $k_La$ very large up to 1g/L regardless the type. PPG was less effect on $k_La$ than other antiforms. The impeller spacing and presence of solute are found very effective on $k_La$. When the $NaNO_3$is presented as solute, the $k_La$ increased approximately 50% then control.

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Micro Emulsion Synthesis of LaCoO3 Nanoparticles and their Electrochemical Catalytic Activity

  • Islam, Mobinul;Jeong, Min-Gi;Ghani, Faizan;Jung, Hun-Gi
    • Journal of Electrochemical Science and Technology
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    • v.6 no.4
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    • pp.121-130
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    • 2015
  • The micro emulsion method has been successfully used for preparing perovskite LaCoO3 with uniform, fine-shaped nanoparticles showing high activity as electro catalysts in oxygen reduction reactions (ORRs). They are, therefore, promising candidates for the air-cathode in metal-air rechargeable batteries. Since the activity of a catalyst is highly dependent on its specific surface area, nanoparticles of the perovskite catalyst are desirable for catalyzing both oxygen reduction and evolution reactions. Herein, LaCoO3 powder was also prepared by sol-gel method for comparison, with a broad particle distribution and high agglomeration. The electro catalytic properties of LaCoO3 and LaCoO3-carbon Super P mixture layers toward the ORR were studied comparatively using the rotating disk electrode technique in 0.1 M KOH electrolyte to elucidate the effect of carbon Super P. Koutecky-Levich theory was applied to acquire the overall electron transfer number (n) during the ORR, calculated to be ~3.74 for the LaCoO3-Super P mixture, quite close to the theoretical value (4.0), and ~2.7 for carbon-free LaCoO3. A synergistic effect toward the ORR is observed when carbon is present in the LaCoO3 layer. Carbon is assumed to be more than an additive, enhancing the electronic conductivity of the oxide catalyst. It is suggested that ORRs, catalyzed by the LaCoO3-Super P mixture, are dominated by a 2+2-electron transfer pathway to form the final, hydroxyl ion product.

Dependence of LaAlO3/SrTiO3 Interfacial Conductivity on the Thickness of LaAlO3 Layer Investigated by Current-voltage Characteristics (LaAlO3 두께에 따른 LaAlO3/SrTiO3 계면에서의 전류-전압 특성을 이용한 전도성 변화 연구)

  • Moon, Seon-Young;Baek, Seung-Hyub;Kang, Chong-Yun;Choi, Ji-Won;Choi, Heon-Jin;Kim, Jin-Sang;Jang, Ho-Won
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.25 no.8
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    • pp.616-619
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    • 2012
  • Oxides possess several interesting properties, such as ferroelectricity, magnetism, superconductivity, and multiferroic behavior, which can effectively be used oxide electronics based on epitaxially grown heterostructures. The microscopic properties of oxide interfaces may have a strong impact on the electrical transport properties of these heterostructures. It was recently demonstrated that high electrical conductivity and mobility can be achieved in the system of an ultrathin $LaAlO_3$ film deposited on a $TiO_2$-terminated $SrTiO_3$ substrate, which was a remarkable result because the conducting layer was at the interface between two insulators. In this study, we observe that the current-voltage characteristics exhibit $LaAlO_3$ thickness dependence of electrical conductivity in $TiO_2$-terminated $SrTiO_3$. We find that the $LaAlO_3$ layers with a thickness of up 3 unit cells, result in highly insulating interfaces, whereas those with thickness of 4 unit cells and above result in conducting interfaces.

Microstructure and dielectric properties in the La2O3-doped BaTiO3 system (La2O3 첨가에 따른 BaTiO3의 미세구조 및 유전특성)

  • Choi, Woo-Jin;Moon, Kyoung-Seok
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.30 no.3
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    • pp.103-109
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    • 2020
  • The effect of La2O3 addition on the crystalline phase, microstructure, and dielectric properties of BaTiO3 has been studied as a function of the amounts of La2O3. 0.3 mol% TiO2-excess BaTiO3 powder was synthesized by solid-state reaction, and then the powder compacts with various amounts of La2O3 were sintered at 1250℃ for 2 hours. Room temperature XRD showed changes in the lattice parameters and a decrease of tetragonality (c/a) as the amounts of La2O3 increased. It can be explained that the phase transition from tetragonal to cubic phase occurred because La3+ replaced Ba2+ site, which increased the instability of the tetragonal phase. As La2O3 was added over 0.1 mol%, the critical driving force for growth (Δgc) increased over maximum driving force (Δgmax). As the result, the grain size decreased with La2O3 addition. Dielectric constant decreased as the amounts of La2O3 increased, which was analyzed with crystal structure and microstructure.

Globotriaosylceramide (Gb3) content in HeLa cells is correlated to Shiga toxin-induced cytotoxicity and Gb3 synthase expression

  • Shin, In-Sun;Ishii, Satoshi;Shin, Jong-Seo;Sung, Kyong-Il;Park, Byung-Sung;Jang, Hyun-Yong;Kim, Byong-Wan
    • BMB Reports
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    • v.42 no.5
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    • pp.310-314
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    • 2009
  • Globotriaosylceramide (Gb3) and globotetraosylceramide (Gb4) are the proposed functional receptors for Shiga toxin (Stx). To elucidate the effect of Gb3 content on Stx-induced cytotoxicity in HeLa cells, we cloned HeLa cells and determined the correlation between glycolipids content and Stx-induced cytotoxicity. The 29 HeLa cell clone (HLCC) lines used showed a wide range of sensitivity to Stx, compared to Gb3-rich cells which were more sensitive, showing as little as 20% viability to 100 pg/ml Stx. In contrast, Gb3-deficient cells proved resistant as they were more than 80% viable to 100 ng/ml Stx. Gb3 content in the HLCC lines corresponded with Stxs-induced cytotoxicity as well as Gb3 synthase expression, but no correlation with Gb4 content was noted. These data show that Gb3 content, which is regulated by the expression of Gb3 synthase, determines the sensitivity of HeLa cells toward Stx.