• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.6
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• pp.659-670
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• 2017

Oxidative stress and inflammation are key factors responsible for progression of liver injury. A variety of functions of oyster hydrolysate (OH) are affected by their antioxidant and anti-inflammatory activities. However, little is known regarding the effects of OH on a liver injury model. This study was performed to evaluate the effects of OH on acute liver injury induced by lipopolysaccharide/D-galactosamine (LPS/D-GalN) in mice. Experimental groups were divided into six groups as follows (each group, n=10): control (saline), LPS/D-GalN, LPS/D-GalN+OH (100 mg/kg), LPS/D-GalN+OH (200 mg/kg), LPS/D-GalN+OH (400 mg/kg), and LPS/D-GalN+silymarin (25 mg/kg, positive control). The experimental acute liver injury model was induced with LPS ($1{\mu}g/kg$) and D-GalN (400 mg/kg). We first analyzed antioxidant and anti-inflammatory activities in OH. OH showed high DPPH and ABTS radical scavenging activities and reduced ROS generation in Chang cells in a dose-dependent manner. In addition, OH showed anti-inflammatory activities, such as inhibition of cyclooxygenase-2 and 5-lipooxygenase. Treatment with OH down-regulated tumor necrosis factor $(TNF)-{\alpha}$, interleukin (IL)-6, and $IL-1{\alpha}$ expression levels in LPS-stimulated RAW264.7 cells. OH significantly reduced LPS/D-GalN-induced increases in the concentrations of alanine transaminase and aspartate aminotransferase in serum. In the LPS/D-GalN group, liver tissues exhibited apoptosis of hepatocytes with hemorrhages. These pathological alterations were ameliorated by OH treatment. Consistently, hepatic catalase activity was low in the LPS/D-GalN group compared to the control group, and catalase activity was significantly restored by OH treatment (P<0.05). Furthermore, OH markedly reduced the LPS/D-GalN-induced increase in $TNF-{\alpha}$, $IL-1{\beta}$, and IL-6 levels in liver tissue. Taken together, these results show that OH has hepatoprotective effects on LPS/D-GalN-induced acute liver injury via inhibition of oxidative stress and inflammation, suggesting that OH could be used as a health functional food and potential therapeutic agent for acute liver injury.

• Communications of the Korean Mathematical Society
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• v.20 no.4
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• pp.703-708
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• 2005

Let ${\varphi}(z)\;=\;({\varphi}_1(Z),{\cdots},{\varphi}_n(Z))$ be a holomorphic self­map of $\mathbb{D}^n$, where $\mathbb{D}^n$ is the unit polydisk of $\mathbb{C}^n$. The sufficient and necessary conditions for a composition operator to be bounded and compact from the Hardy space $H^2(\mathbb{D}^n)$ into $\alpha$-Bloch space $\beta^{\alpha}(\mathbb{D}^n)$ on the polydisk are given.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.5
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• pp.430-433
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• 2017

This paper presents a S/C/X-band LNA MMIC with resistive feedback structure in 0.25 um GaN HEMT process. The GaN devices have advantages as a high output power device having high breakdown voltage, energy band gap and stability at high temperature. Since the receiver using the GaN device with high linearity can be implemented without a limiter, the noise figure of the receiver can be improved and the size of receiver module can be reduced. The proposed GaN LNA MMIC based on 0.25 um GaN HEMT device is achieved the gain of > 15 dB, the noise figure of < 3 dB, the input return loss of > 13 dB, and the output return loss of > 8 dB in the S/C/X-band. The current consumption of GaN LNA MMIC is 70 mA with the drain voltage 20 V and the gate voltage -3 V.

• Journal of Information Display
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• v.10 no.1
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• pp.6-15
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• 2009

In this paper, a new approach is proposed for the efficient generation of computer-generated holograms (CGHs) using the spatially redundant data on a 3D object and the novel look-up table (N-LUT) method. First, the pre-calculated N-point principle fringe patterns (PFPs) were calculated using the 1-point PFP of the N-LUT. Second, spatially redundant data on a 3D object were extracted and re-grouped into the N-point redundancy map using the run-length encoding (RLE) method. Then CGH patterns were generated using the spatial redundancy map and the N-LUT method. Finally, the generated hologram patterns were reconstructed. In this approach, the object points that were involved in the calculation of the CGH patterns were dramatically reduced, due to which the computational speed was increased. Some experiments with a test 3D object were carried out and the results were compared with those of conventional methods.

• Journal for History of Mathematics
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• v.24 no.4
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• pp.1-6
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• 2011

We investigate a method to find the least common multiples of numbers in the mathematics book GuIlJib(구일집(九一集), 1724) written by the greatest mathematician Hong Jung Ha(홍정하(洪正夏), 1684~?) in Chosun dynasty and then show his achievement on Number Theory. He first noticed that for the greatest common divisor d and the least common multiple l of two natural numbers a, b, l = $a\frac{b}{d}$ = $b\frac{a}{d}$ and $\frac{a}{d}$, $\frac{b}{d}$ are relatively prime and then obtained that for natural numbers $a_1,\;a_2,{\ldots},a_n$, their greatest common divisor D and least common multiple L, $\frac{ai}{D}$($1{\leq}i{\leq}n$) are relatively prime and there are relatively prime numbers $c_i(1{\leq}i{\leq}n)$ with L = $a_ic_i(1{\leq}i{\leq}n)$. The result is one of the most prominent mathematical results Number Theory in Chosun dynasty. The purpose of this paper is to show a process for Hong Jung Ha to capture and reveal a mathematical structure in the theory.

• Journal of Aquaculture
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• v.17 no.4
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• pp.275-281
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• 2004

The present study was conducted to evaluate dietary requirements for essential fatty acids (EFAs) such as linoleic acid (LA, l8:2n-6), -lenolenic acid (LNA, 18:3n-3), or docosahexaenoic acid (DHA, 22:6n-3), eicosapentaenoic acid (EPA, 20:5n-3) and arachidonic acid (ARA, 20:4n-6) in juvenile eel Anguilla japonica cultured in a recirculating system for 16 weeks. The experimental diets contained 50% crude protein, 10% crude lipid and 3800 kcal/kg energy.Brown fish meal and blood meal were used as the main protein sources, while coconut oil, com oil and linseed oil were used as the lipid source to yield target fatty acids ratios. At the end of the trial, the effects of essential fatty acids supplementation on weight gain (WG), specific growth rate (SGR), feeding efficiency (FE), proximate composition andwhole body fatty acids contents were examined. WG, SGR, and FEof eels fed diet D2, D3, was significantly higher (P<0.05) than those of fish fed the other diets. Whole body HUFA concentration of eels fed D 1 was significantly lower (P<0.05) than those fed the other diets. HUFA/SFA (saturated fatty acids) ratio of whole body in eels fed diets D2, D3 and D6 were significantly higher than that of eels fed diet D1 (P<0.05).DHA/EPA ratio of whole body in eels fed diet D7was significantly higher than those fed the other diets; and eels fed diet D5 showed the lowest DHA/EPA ratio among all the dietary treatments (P<0.05).Based on the experimental results, we concluded that LNA (n-3) and LA (n-6) were necessary for optimum growth of juvenile eel, and the dietary requirement of LNA and LA were 0.35∼0.5% and 0.5∼0.65%, respectively.

• The Pure and Applied Mathematics
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• v.20 no.4
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• pp.243-249
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• 2013

Let A be an algebra and D a derivation of A. Then D is called algebraic nil if for any $x{\in}A$ there is a positive integer n = n(x) such that $D^{n(x)}(P(x))=0$, for all $P{\in}\mathbb{C}[X]$ (by convention $D^{n(x)}({\alpha})=0$, for all ${\alpha}{\in}\mathbb{C}$). In this paper, we show that any algebraic nil derivation (possibly unbounded) on a commutative complex algebra A maps into N(A), where N(A) denotes the set of all nilpotent elements of A. As an application, we deduce that any nilpotent derivation on a commutative complex algebra A maps into N(A), Finally, we deduce two noncommutative versions of algebraic nil derivations inclusion range.

• The korean journal of orthodontics
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• v.25 no.3 s.50
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• pp.333-339
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• 1995

The hormonally active vitamin D metabolite, 1,25-dihydroxy vitamin $D_3[1.25-(OH)_2D_3]$ is one of the several humoral factors that may regulate osteoblast differentiation. The purpose of this study was to evaluate the effects of $1,25-(OH)_2D_3$ on the PDL cells. Human PDL cells were prepared from the first premolar tooth extracted for the orthodontic treatment and they were incubated in the environment of $37^{\circ}C,\;5\%\;CO_2\;and\;95\%$ humidity. $[{^3}H]$-thymidine incorporation as a measure of proliferation potential and alkaline phosphatase activity were evaluated at 10nM, 100nM $1,25-(OH)_2D_3$. The observed results were as follows. 1. $1,25-(OH)_2D_3$ was significantly enhanced $[{^3}H]$-thymidine incorporation at 100nM, But did not affect by 10nM. 2. $1,25-(OH)_2D_3$ was significantly increased alkaline phosphatase activity at 1 day and 6 days in a dose-dependent manner.

• Imaging Science in Dentistry
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• v.31 no.1
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• pp.1-7
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• 2001

Purpose : To evaluate the usefulness of the reconstructed 3-dimensional image on the personal computer in comparison with that of the CT workstation by quantitative comparison and analysis. Materials and Methods : The spiral CT data obtained from 27 persons were transferred from the CT workstation to a personal computer, and they were reconstructed as 3-dimensional image on the personal computer using V-works 2.0/sup TM/. One observer obtained the 14 measurements on the reconstructed 3-dimensional image on both the CT workstation and the personal computer. Paired Nest was used to evaluate the intraobserver difference and the mean value of the each measurement on the CT workstation and the personal computer. Pearson correlation analysis and % incongruence were also performed. Results: I-Gn, N-Gn, N-A, N-Ns, B-A, and G-Op did not show any statistically significant difference (p>0.05), B-O, B-N, Eu-Eu, Zy-Zy, Biw, D-D, Orbrd R, and L had statistically significant difference (p<0.05), but the mean values of the differences of all measurements were below 2 mm, except for D-D. The value of correlation coefficient y was greater than 0.95 at I-Gn, N-Gn, N-A, N-Ns, B-A, B-N, G-Op, Eu-Eu, Zy-Zy, and Biw, and it was 0.75 at B-O, 0.78 at D-D, and 0.82 at both Orbrd Rand L. The % incongruence was below 4% at I-Gn, N-Gn, N-A, N-Ns, B-A, B-N, G-Op, Eu-Eu, Zy-Zy, and Biw, and 7.18%, 10.78%, 4.97%, 5.89% at B-O, D-D, Orbrd Rand L respectively. Conclusion : It can be considered that the utilization of the personal computer has great usefulness in reconstruction of the 3-dimensional image when it comes to the economics, accessibility and convenience, except for thin bones and the landmarks which are difficult to be located.

• The Journal of Korean Association of Computer Education
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• v.17 no.2
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• pp.115-124
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• 2014

Hypercube and star graph are widely known as interconnection network. The embedding of an interconnection network is a mapping of a network G into other network H. The possibility of embedding interconnection network G into H with a low cost, has an advantage of efficient algorithms usage in network H, which was developed in network G. In this paper, we provide an embedding algorithm between HCN and HON. HCN(n,n) can be embedded into HON($C_{n+1},C_{n+1}$) with dilation 3 and HON($C_d,C_d$) can be embedded into HCN(2d-1,2d-1) with dilation O(d). Also, star graph can be embedded to half pancake's value of dilation 11, expansion 1, and average dilation 8. Thus, the result means that various algorithms designed for HCN and Star graph can be efficiently executed on HON and half pancake, respectively.