• Journal of The Korean Astronomical Society
• /
• v.15 no.1
• /
• pp.19-36
• /
• 1982

For ${\sim}240$ nearby stars their age and mass were determined and kinematic parameters determined for 362 stars, applying Woolley's three-dimensional potential. Metallicity and kinematic parameters of these stars were correlated with their age, suggesting the slow collapse ($t{\gtrsim}a$ few billion years) of the Galaxy and the initial rapid enrichment in metal abundance (${\Delta}Z{\approx}1/3Z_1$(present) for ${\sim}4{\times}10^8$ yrs). The late slow enrichment rate is given by $d(Z/Z_{\odot})/dt=5.9{\sim}7.0{\pm}3.4$ per Gyr.

• Journal of Life Science
• /
• v.18 no.11
• /
• pp.1499-1506
• /
• 2008

To examine antitumor activity of the edible plant Zanthoxylum schinifolium, the cytotoxic effect of various organic solvent extracts of its stems on human acute leukemia Jurkat T cells was investigated. Among these extracts such as methanol extract (SS-7), methylene chloride extract (SS-8), ethyl acetate extract (SS-9), n-butanol extract (SS-10), and residual fraction (SL-11), SS-8 exhibited the most cytotoxic activity against Jurkat T cells. The methylene chloride extract (SS-8) possessed the apoptogenic activity capable of inducing sub-G1 peak along with apoptotic DNA fragmentation in Jurkat T cells. Western blot analysis revealed that SS-8 induced apoptosis via mitochondrial cytochrome c release into cytoplasm, subsequent activation of caspase-9 and caspase-3, and cleavage of PARP, which could be blocked by overexpression of Bcl-xL. Jurkat T cell clone I2.1 $FADD^{-/-}$) and Jurkat T cell clone I9.2 (caspase-$8^{-/-}$ were as sensitive as was the wild-type Jurkat T cell clone A3 to the cytotoxic effect of SS-8, suggesting no contribution of Fas/FasL system to the SS-8-mediated apoptosis. The GC-MS analysis of SS-8 showed that it was composed of 16 ingredients including 9,12-octadecanoic acid (18.62%), 2,4-dihydro-5-methyl-4- (1-methylethylidene)- 2-(4-nitrophenyl)-3H- pyrazol-3-one (14.97%), hexadecanoic acid (14.23%), (z,z)-6,9-pentadecadien- 1-ol (13.73%), 5,6-dimethoxy-2-methyl benzofuran (10.95%), and 4-methoxy-2-methylcinnamic acid (5.38%). These results demonstrate that the methylene chloride extract of the stems of Z. schinifolium can induce apoptotic cell death in Jurkat T cells via intrinsic mitochondria-dependent caspase cascade regulated by Bcl-xL without involvement of the Fas/FasL system.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.56 no.2
• /
• pp.172-182
• /
• 2020

In order to offer specific information needed to assist in operation of a ship with same type rudder through evaluating the maneuverability of training ship A-Ra with flapped rudder, sea trials based full scale for turning test, zig-zag test with rudder angle 10° and 20°, and spiral test at service condition were carried out on starboard and port sides around Jeju Island according to the standards of maneuverability of IMO. As a result, the angular velocity of port turn was higher than that of starboard turn. Therefore, the size of turning circle was longer on the starboard side. In addition, variation of the transfer due to various factors was more stable than those of the others. In the Z-test results, the mean of 1st and 2nd overshoot angles were 9.8°, 6.3° and 15.3°, 9.2° respectively when the port and starboard was 10°; the 1st overshoot angle were 18°, 13.7° when using 20°. Her maneuverability index T' and K' can be easily determined by using a computer with the data obtained from Z-test where K' and T' are dimensionless constants representing turning ability and responsiveness to the helm, respectively. In the Z-test under flap rudder angle 10°, the obtained K' value covered the range of 2.37-2.87 and T' was 1.74-3.45. Under the flap rudder angle 20°, K' and T' value showed 1.43-1.63, 1.0-1.73, respectively. In the spiral test, the loop width was unstable at +0.3° and -0.5°-0.9° around the midship of flap rudder. As a result, course stability was comparatively good. From the sea trial results, training ship ARA met the present criterion in the standards of maneuverability of IMO.

• Journal of the Korean Mathematical Society
• /
• v.44 no.5
• /
• pp.1139-1162
• /
• 2007

We examine the main linear coding theory problem and study the structure of optimal linear codes over the ring ${\mathbb{Z}}_m$. We derive bounds on the maximum Hamming weight of these codes. We give bounds on the best linear codes over ${\mathbb{Z}}_8$ and ${\mathbb{Z}}_9$ of lengths up to 6. We determine the minimum distances of optimal linear codes over ${\mathbb{Z}}_4$ for lengths up to 7. Some examples of optimal codes are given.

• Journal of Sericultural and Entomological Science
• /
• v.51 no.2
• /
• pp.185-190
• /
• 2013

The superworm, as known the larva of Zophobas morio, has been officially imported from 2011 and bred commercially in Korea. But it is named as the corrected scientific name, Zophobas atratus by junior synonym throughout traditional taxonomy in this study and newly designated Korean name as 'a-me-ri-ca-wang-geo-jeo-ri' in terms of resource management. Z. atratus was compared with wild native tenebrionids, Promethis valgipes and a commercial reared Tenebrio molitor on the basis of DNA barcode analysis. As the results, the average genetic divergence was 21.4% between Z. atratus and P. valgipes, and 20.9% between Z. atratus and T. molitor. These large divergences imply these tenebrionids species can be easily identified by DNA barcodes. The results of genetic divergences within species also suggest that Korean populations of Z. atratus, having the same haplotype, might be introduced from the same area of foreign country. On the other hand, a population of T. molitor was separated into two distinct intra-specific groups with DNA barcoding gaps ranged from 1.17- 2.19%. We suppose that domestic breeding entities of T. molitor might be introduced and mixed from two different local groups. Through this study, we expect that classification for two tenebrionid introduced from foreign countries can be used for the management of insect resources in Korea.

• Bulletin of the Korean Chemical Society
• /
• v.16 no.9
• /
• pp.839-844
• /
• 1995

The kinetics and mechanism of the reactions of phenyl benzoates with benzylamines and pyrrolidine are investigated in acetonitrile. The variations of ρX (ρXY>0) and ρZ (ρYZ<0) with respect to the substituent in the substrate (σY) indicate that the reactions proceed through a tetrahedral intermediate, T±, with its breakdown in the rate determining step. The large magnitudes of ρZ, ρXY and ρYZ as well as the effects of secondary kinetic isotope effects involving deuterated nucleophiles are also in line with the proposed mechanism.

• Korean Journal of Ichthyology
• /
• v.22 no.4
• /
• pp.238-248
• /
• 2010

We performed field investigations at six stations in Buk Stream of Goseong-gun, Gangwon-do, Korea, from May to September 2009 to understand the stream's fish fauna and community structure. In the survey, 31 species belonging to 20 families were collected. Dominant species by number was Zacoo koreanus (30.0%), and subdominant species were Pungitius kaibarae (9.4%) and Rhynchocypris steindachneri (9.3%). In biomass, the dominant species was Tribolodon hakonensis (35.5%), and subdominant species were Z. koreanus (22.5%) and Cobitis pacifica (7.5%). Eight Korean endemic fish species and two endangered species (P. kaibarae and Pungitius sinensis) were collected. In addition, four anadromous fish species (T. hakonensis, Oncorhynchus masou masou, O. keta, Gasterosteus aculeatus) and two amphidromus fish species (Plecoglossus altivelis altivelis and Gymnogobius urotaenia) were observed. Interestingly, we verified the existence of several fish species in Buk Stream where they have not lived before. Those species were previously reported to live only in rivers that run into the western and southern sea of Korea. Five of those species (Zacoo koreanus, Z. platypus, Silurus microdorsalis, Liobagrus andersoni and Coreoperca herzi) were reported in Buk Stream in the 1980s. The other species (Pungtungia herzi, Pseudorasbora parva, Squalidus multimaculatus, Misgurnus mizolepis, Koreocobitis rotundicaudata, Silurus asotus and Odontobutis interrupta) have been introduced since the 1990s.

• Geomechanics and Engineering
• /
• v.29 no.1
• /
• pp.25-40
• /
• 2022

In this study, 3D coupled-consolidation numerical parametric study was conducted to predict the deformation mechanism of a 20 storey building sitting on (4×4) piled raft (with length of piles, L_p=30 m) to adjacent 6 m diameter (D) tunnelling in stiff clay. The influences of different tunnel locations relative to piles (i.e., z_t/L_p) were investigated in this parametric study. In first case, the tunnel was excavated near the pile shafts with depth of tunnel axis (z_t) of 9 m (i.e., z_t/L_p). In second and third cases, tunnels were driven at z_t of 30 m and 42 m (i.e., z_t/L_p = 1.0 and 1.4), respectively. An advanced hypoplastic clay model (which is capable of taking small-strain stiffness in account) was adopted to capture soil behaviour. The computed results revealed that tunnelling activity adjacent to a building resting on piled raft caused significant settlement, differential settlement, lateral deflection, angular distortion in the building. In addition, substantial bending moment, shear forces and changes in axial load distribution along pile length were induced. The findings from the parametric study revealed that the building and pile responses significantly influenced by tunnel location relative to pile.

• Journal of Life Science
• /
• v.19 no.11
• /
• pp.1529-1537
• /
• 2009

To elucidate further the antitumor effects of a natural L-arginine analogue, L-canavanine, the mechanism underlying apoptogenic activity of L-canavanine and its modulation by protein tyrosine kinase $p56^{lck}$ was investigated in human Jurkat T cells. When the cells were treated with 1.25 to 2.5 mM L-canavanine for 36 h, several apoptotic events including mitochondrial membrane potential (${\Delta\Psi}m$) loss, activation of caspase-9, -3, -8, and -7, poly (ADP-ribose) polymerase (PARP) degradation, and DNA fragmentation were induced without alteration in the levels of Fas or FasL. These apoptotic changes were more significant in $p56^{lck}$-deficient Jurkat clone JCaM1.6 than in $p56^{lck}$-positive Jurkat clone E6.1. The L-canavanine-induced apoptosis observed in $p56^{lck}$-deficient JCaM1.6 cells was significantly reduced by introducing $p56^{lck}$ gene into JCaM1.6 cells by stable transfection. Treatment of JCaM1.6/lck cells with L-canavanine caused a transient 1.6-fold increase in the kinase activity of $p56^{lck}$. Both FADD-positive wild-type Jurkat T cell clone A3 and FADD-deficient Jurkat T cell clone I2.1 exhibited a similar susceptibility to the cytotoxicity of L-canavanine, excluding involvement of Fas/FasL system in triggering L-canavanine-induced apoptosis. The L-canavanine-induced apoptotic sub-$G_1$ peak and activation of caspase-3, -8, and -7 were abrogated by pan-caspase inhibitor (z-VAD-fmk), whereas L-canavanine-induced activation of caspase-9 was not affected. These results demonstrated that L-canavanine caused apoptosis of Jurkat T cells via the loss of ${\Delta\Psi}m$, and the activation of caspase-9, -3, -8, and -7, leading to PARP degradation, and that the $p56^{lck}$ kinase attenuated the ${\Delta\Psi}m$ loss and activation of caspases, and thus contributed as a negative regulator to L-canavanine-induced apoptosis.

• Progress in Superconductivity and Cryogenics
• /
• v.15 no.2
• /
• pp.16-19
• /
• 2013

The magneto-resistivity and electric field-current density (E-J) curves were investigated up to a magnetic field 9 T in the optimally doped $BaFe_{1.8}Co_{0.2}As_2$ single crystal with a superconducting temperature ($T_c$) of 24.6 K. The E-J Scaling behaviors below and above vortex glass transition temperature ($T_g$) were found, confirming the existence of the vortex glass phase transition. The critical exponents for the diverging spatial and time correlations at $T_g$, were obtained as v = $1.1{\pm}0.1$ and z = $4.5{\pm}0.3$, respectively. The obtained critical exponents are in good agreement with the predicted values of v ~ 1 - 2 and z > 4 within the 3D vortex glass theory.