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Diagnosis and Treatment of Brown Tumor (Brown 종양의 진단 및 치료)

  • Cho, Yong Jin;Cho, Yung Min;Na, Seung Min;Jung, Sung-Taek
    • Journal of the Korean Orthopaedic Association
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    • v.55 no.1
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    • pp.54-61
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    • 2020
  • Purpose: Brown tumor is a tumor-like disease that can occur as a linked disease of hyperparathyroidism which can causes osteoporosis, osteitis fibrosa cystica, pathologic fractures. Brown tumor has been reported as a case report, but there is no comprehensive report on the exact diagnosis and principle of management for osseous lesion. The purpose of this study is to report the treatment and results of osseous lesions through 5 cases. Materials and Methods: From February 2004 to May 2015, five cases of Brown tumor were diagnosed in Chosun University Hospital and Chonnam National University Hospital orthopedic department. Medical records and radiographs were reviewed retrospectively. Parathyroid tumors were surgically removed, and surgical treatment and observation were performed for orthopedic osseous lesions. Results: The mean length of the long axis of the symptomatic osseous lesion was 6.2 cm (4.5-9.0 cm). An average of 7.6 (range, 3 to 14) of high uptake osseous lesion showed in whole body bone scan. The absolute value, T-score and Z-score of the vertebrae and proximal femur were adequate for diagnosis of osteoporosis using dual energy X-ray absorptiometry bone mineral density at diagnosis and recovered to normal at the last follow-up. In laboratory tests, serum concentrations of total calcium, ionized calcium, inorganic phosphorus, serum alkaline phosphatase, and parathyroid hormone were helpful to diagnosis and normalized upon successful removal of parathyroid adenoma or cancer. Conclusion: For accurate diagnosis of Brown tumor, it should be accompanied by systemic examination as well as clinical symptoms, laboratory tests and radiologic examination for osseous lesions. And a good prognosis can be expected if the hyperparathyroidism is treated together with the comprehensive treatment of osseous lesions.

Heavy concrete shielding properties for carbon therapy

  • Jin-Long Wang;Jiade J Lu;Da-Jun Ding;Wen-Hua Jiang;Ya-Dong Li;Rui Qiu;Hui Zhang;Xiao-Zhong Wang;Huo-Sheng Ruan;Yan-Bing Teng;Xiao-Guang Wu;Yun Zheng;Zi-Hao Zhao;Kai-Zhong Liao;Huan-Cheng Mai;Xiao-Dong Wang;Ke Peng;Wei Wang;Zhan Tang;Zhao-Yan Yu;Zhen Wu;Hong-Hu Song;Shuo-Yang Wei;Sen-Lin Mao;Jun Xu;Jing Tao;Min-Qiang Zhang;Xi-Qiang Xue;Ming Wang
    • Nuclear Engineering and Technology
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    • v.55 no.6
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    • pp.2335-2347
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    • 2023
  • As medical facilities are usually built at urban areas, special concrete aggregates and evaluation methods are needed to optimize the design of concrete walls by balancing density, thickness, material composition, cost, and other factors. Carbon treatment rooms require a high radiation shielding requirement, as the neutron yield from carbon therapy is much higher than the neutron yield of protons. In this case study, the maximum carbon energy is 430 MeV/u and the maximum current is 0.27 nA from a hybrid particle therapy system. Hospital or facility construction should consider this requirement to design a special heavy concrete. In this work, magnetite is adopted as the major aggregate. Density is determined mainly by the major aggregate content of magnetite, and a heavy concrete test block was constructed for structural tests. The compressive strength is 35.7 MPa. The density ranges from 3.65 g/cm3 to 4.14 g/cm3, and the iron mass content ranges from 53.78% to 60.38% from the 12 cored sample measurements. It was found that there is a linear relationship between density and iron content, and mixing impurities should be the major reason leading to the nonuniform element and density distribution. The effect of this nonuniformity on radiation shielding properties for a carbon treatment room is investigated by three groups of Monte Carlo simulations. Higher density dominates to reduce shielding thickness. However, a higher content of high-Z elements will weaken the shielding strength, especially at a lower dose rate threshold and vice versa. The weakened side effect of a high iron content on the shielding property is obvious at 2.5 µSv=h. Therefore, we should not blindly pursue high Z content in engineering. If the thickness is constrained to 2 m, then the density can be reduced to 3.3 g/cm3, which will save cost by reducing the magnetite composition with 50.44% iron content. If a higher density of 3.9 g/cm3 with 57.65% iron content is selected for construction, then the thickness of the wall can be reduced to 174.2 cm, which will save space for equipment installation.

The Crystal and Molecular Structure of Acetone 4-Benzylthiosemicarbazone (Acetone 4-Benzylthiosemicarbazone의 결정 및 분자구조)

  • Park Young Ja;Ahn Choong Tai
    • Journal of the Korean Chemical Society
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    • v.29 no.2
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    • pp.73-79
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    • 1985
  • The crystal and molecular structure of acetone 4-benzylthiosemicarbazone, $C_{11}H_{15}N_3S$, has been determined by the single crystal X-ray diffraction methods. The crystals are monoclinic, space group $P2_1/c$ with unit cell dimensions, a = 10.249(7), b = 11.403(9), c = 10.149(7)TEX>${\AA}$, ${\beta}$ = 90.9$(1)^0$ and z = 4. The intensities were collected on an automatic four-circle diffractometer with graphite-monochromated Mo-$K_{\alpha}$ radiation. The structure was solved by direct methods and refined by full matrix least-squares methods. The final R was 0.045 for 1554 observed reflections. S-C(8)-N(2)-N(3)-C(9)-C(10) atoms make a zigzag planar chain. There are no unusual bond lengths and angles. There are two independent hydrogen bonds in the crystal structure. One is N-H${\cdots}$S intermolecular hydrogen bond with the length of 3.555${\AA}$ and makes dimer-like units. The other is N-H${\cdots}$N intramolecular hydrogen bond with the length of 2.568${\AA}$. The structure was compared with those of other thiosemicarbazone derivatives.

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3D Modeling from 2D Stereo Image using 2-Step Hybrid Method (2단계 하이브리드 방법을 이용한 2D 스테레오 영상의 3D 모델링)

  • No, Yun-Hyang;Go, Byeong-Cheol;Byeon, Hye-Ran;Yu, Ji-Sang
    • Journal of KIISE:Software and Applications
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    • v.28 no.7
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    • pp.501-510
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    • 2001
  • Generally, it is essential to estimate exact disparity for the 3D modeling from stereo images. Because existing methods calculate disparities from a whole image, they require too much cimputational time and bring about the mismatching problem. In this article, using the characteristic that the disparity vectors in stereo images are distributed not equally in a whole image but only exist about the background and obhect, we do a wavelet transformation on stereo images and estimate coarse disparity fields from the reduced lowpass field using area-based method at first-step. From these coarse disparity vectors, we generate disparity histogram and then separate object from background area using it. Afterwards, we restore only object area to the original image and estimate dense and accurate disparity by our two-step pixel-based method which does not use pixel brightness but use second gradient. We also extract feature points from the separated object area and estimate depth information by applying disparity vectors and camera parameters. Finally, we generate 3D model using both feature points and their z coordinates. By using our proposed, we can considerably reduce the computation time and estimate the precise disparity through the additional pixel-based method using LOG filter. Furthermore, our proposed foreground/background method can solve the mismatching problem of existing Delaunay triangulation and generate accurate 3D model.

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Ecological Characteristics and Change for fifteen Years$(1990$\sim2004)$ of Plant Community Structure of the Pinus densiflora S. et Z. Forest in Namsan, Seoul (서울시 남산소나무림 생태적 특성 및 15년간(1990$\sim$2004년) 식생구조 변화분석)

  • Lee Kyong-Jae;Kim Jeong-Ho;Han Bong-Ho
    • Korean Journal of Environment and Ecology
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    • v.19 no.3
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    • pp.312-326
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    • 2005
  • The purpose of this study is to provide data for conservation and ecological management of Pinus densiflora forest by analyzing ecological characteristics and the change of Pin us densiflora community structure for fifteen years in Namsan(Mt.). The actual vegetation of Pinus densiflora forest was divided into total six types and fifteen detail types. According to the results of TWINSPAN analysis of Pinus densiflora forest, there were fourty-four plots(unit: 400 m') and it was classified into five community types. The dominant species were Pinus densiflora in canopy layer, Styrax japonica in the understory layer and Stephanandra incisa with Rhododendron mucronujatum in the shrub layer. The index of shannon's diversity was from 1.5980 to 1.1485 per $400m^2$and the range of species number was from seventeen to twenty-two. As a result of the change of Pin us densinora forest structure, the importance percentage(1.p.) of Pinus densi. nora$(I.P.:\;77.9\%\rightarrow50.6\%) was decreased, Styraxjaponica$(I.P.:\;5.3\%\rightarrow22.6\%), Prunus sargen $(I.P.:\;1.5\%\rightarrow9.2\%) and Stephanandra incisa$(I.P.:\;3.5\%\rightarrow7.7\%) were increased for fifteen years. Based on standard of $2,000m^2$unit area, shannon's diversity changed 1.1719 into 0.8829 and species number changed thirty-four into twenty-one.

Annual Equilibrium Moisture Content of Wood in Korea (한국(韓國)의 목재평형함수율(木材平衡含水率))

  • Jo, Jae-Myeong;Kang, Sun-Goo;Shim, Chong-Supp;Jung, Hee-Suk
    • Journal of the Korean Wood Science and Technology
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    • v.10 no.3
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    • pp.109-117
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    • 1982
  • In order to investigate the annual mean equilibrium moisture content (EMC), the equilibrium moisture content investigated were the desorbed - and adsorbed equilibrium moisture content with two end-matched samples for red pine (Pinus densiflora S. et Z.), Douglas fir (Pseadotsuga menziesii Franco), oak (Quercus mongolica Fischer) and red lauan (Shorea spp.) in instrument screen at forest experiment station located in Seoul, Chuncheon, Daejeon, Kyungju, Jinju and Gwangju area for four years (1970. 1 - 1973. 12). The results summarized were as follows. 1. The annual mean desorbed equilibrium moisture content of red pine, Douglar fir, oak and red lauan were 14.8, 13.7, 14.0 and 14.2 percent respectively and higher than the annual mean adsorbed equilibrium moisture content of those species. 2. The annual mean desorbed - and adsorbed equilibrium moisture content in central areas (Seoul, Chuncheon, Daejeon) were higher than those in southern areas (Kyungju, Jinju, Gwangju). 3. On the whole, the monthly mean desorbed - and adsorbed equilibrium moisture content were lowest in April and highest in August though difference of month in areas. 4. Average and range of annual national equilibrium moisture content was 12.3 ~ 14.2 ~ 15.7 percent for desorbed equilibrium moisture content and 11.3 ~ 13.2 ~ 14.7 percent for adsorbed equilibrium moisture content and 12.0 ~ 14.1 ~ 16.4 percent for calculated equilibrium moisture content based on tempera.

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Parthenogenetic Activation of Porcine Oocytes and Isolation of Embryonic Stem Cells-like Derived from Parthenogenetic Blastocysts

  • Xu, X.M.;Hua, J.L.;Jia, W.W.;Huang, W.;Yang, C.R.;Dou, Z.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.10
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    • pp.1510-1516
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    • 2007
  • These experiments were carried out to optimize the parameters of electrical activation, methods of parthenogenetic activation and embryo culture in vitro and meanwhile to isolate embryonic stem cells-like (ESCs) derived from porcine parthenogenetic blastocysts (pPBs). These results showed that, as the electric field strength increased from 1.0 to 2.7 kV/cm, the cleavage rate of parthenogenetic embryos increased gradually but the rate of oocyte lysis was significantly increased when using 2.7 kV/cm field strength. The rate of cleavage in 2.2 and 2.7 kV/cm groups was significantly increased in comparison with that of the 1.0 kV/cm group. A voltage field strength of 2.2 kV/cm DC was used to investigate blastocyst development following activation with a single pulse of 30 or $60-{\mu}sec$ pulse duration. The optimum pulse duration was 30-${\mu}sec$, with a blastocyst rate of 20.7%. Multiple pulses were inferior to a single pulse for blastocyst yield (8.0% vs. 29.9) (p<0.05). For porcine oocyte parthenogenetic activation methods, the rates of cleavage (79.0% vs. 59.8%) and blastocysts (19.4% vs. 3.4%) were significantly increased in electrical activation in contrast to chemical activation with ionomycin/6-DMAP (p<0.05). Rates of cleavage and blastocyst formation in NCSU-23 and PZM-3 embryo media were higher than those of G1.3/G2.3 serial culture media, but there was no significant difference among the three groups. The total cell number of blastocysts in PZM-3 embryo culture media containing $5{\mu}g/ml$ insulin was significantly higher than that of the control (no insulin) ($44.3{\pm}9.1$ vs. $33.9{\pm}11.7$). For isolation of PESCs-like, the rates of porcine blastocysts attached to feeder layers and ICM colony formation in Method B (nude embryo culture) were better than those in Method A (intact embryo culture).

Effects of Fermented Potato Pulp on Performance, Nutrient Digestibility, Carcass Traits and Plasma Parameters of Growing-finishing Pigs

  • Li, P.F.;Xue, L.F.;Zhang, R.F.;Piao, Xiangshu;Zeng, Z.K.;Zhan, J.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.10
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    • pp.1456-1463
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    • 2011
  • A total of 629 Duroc${\times}$Landrace${\times}$Large White crossbred pigs were utilized in three experiments (Exp. 1, 222 pigs weighing $25.6{\pm}2.0\;kg$ BW; Exp. 2, 216 pigs weighing 5$6.2{\pm}4.3\;kg$ BW; Exp. 3, 191 pigs weighing $86.4{\pm}4.6\;kg$ BW) conducted to determine the effects of fermented potato pulp on performance, nutrient digestibility, carcass traits and plasma parameters in growingfinishing pigs. Each experiment lasted 28 d. The pigs were assigned to one of two corn-soybean meal-based diets containing 0 or 5% fermented potato pulp. The inclusion of fermented potato pulp increased weight gain (p<0.05) in experiments 1 and 2 and increased feed intake (p<0.05) in experiment 2. Feed conversion was improved (p<0.05) in experiment 2 and showed a tendency to improve (p<0.10) in experiments 1 and 3 when pigs were fed fermented potato pulp. Fermented potato pulp increased (p<0.05) dry matter digestibility in experiments 1 and 3 and energy digestibility in experiment 2. Feeding fermented potato pulp decreased plasma urea nitrogen (p<0.05) and alanine aminotransferase (p<0.05) in experiments 1 and 2, while plasma aspartate aminotransferase was decreased (p<0.05) in experiment 3. Dietary fermented potato pulp did not affect the carcass characteristics of finishing pigs. Feeding fermented potato pulp reduced (p<0.05) fecal ammonia concentration in all three experiments. In conclusion, feeding growing-finishing pigs diets containing 5% fermented potato pulp improved weight gain and feed conversion without any detrimental effects on carcass traits. The improvements in pig performance appeared to be mediated by improvements in nutrient digestibility.

Species Identification of Wooden Elements Used for Daewungjeon Hall in the Bukjijangsa Temple, Daegu, Korea (대구 북지장사 대웅전 목부재의 수종 식별)

  • Yeon, Jung-A;Park, Won-Kyu
    • Journal of the Korean Wood Science and Technology
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    • v.41 no.3
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    • pp.201-210
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    • 2013
  • The purpose of this study was to examine the species of 117 wooden elements which were used in the Daewungjeon Hall (National Treasure No. 805, constructed in A. D. 1659) of Bukjijangsa Temple, Daegu, Korea. Pillars were identified as 5 red pines (hard pines; most likely, Pinus densiflora S. et Z.), 2 Cerris section of subgenus Lepidobalanus (deciduous oaks) and 3 Tsuga spp. Hwalju columns were 3 Abies spp. and 1 red pine. Head-penetrating ties were 8 red pines and 1 Cerris sp.; Pyeongbang, 3 red pines and 6 Cerris spp. Purlins were identified as 17 red pines, 16 Cerris spp. and 1 Tsuga sp. Angle rafters were 3 red pines and 1 Cerris sp., and end angle rafters, 2 red pines, 1 Zelkova serrata and 1 exotic hard pine. All of brackets (31 woods), jangyeo (4) and deot-chunyeo (2) were identified as red pines. As a whole, red pines (70.1%) and Cerris (22.2%) were major species used in the Daewungjeon Hall of Bukjijangsa Temple. Tsuga, Abies and exotic hard pines seem imported woods used for recent repairs.

A Study on the Exposure to PC Pornography and the Post-Exposure Reactions of Middle School Boys (남자중학생의 컴퓨터음란물 접촉실태와 접촉반응에 대한 조사연구)

  • Kim, Y.-H.;Lee, H.-Z.;Jung, H.-M.
    • The Journal of Korean Academic Society of Nursing Education
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    • v.6 no.1
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    • pp.7-22
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    • 2000
  • The purpose of this study was to identified the level of the exposure to the PC Pornography and what's their post-exposure reactions to the PC pornography. The subjects were 423 middle school boys in Pusan. The survey was executed from July 12 through October 30, 1999. The collected data were analyzed by SPSS WIN using the %, mean, ANOVA. The results of this study were as follows: 1. 79.4%(336 boys) were exposed to the PC pornography. 46.3%(196 boys) answered that they experienced the published pornography prior to the PC pornography. 2. 78.5%(333 boys) answered that they had their PC in their homes. This ratio revealed the higher level of possession. 67.6% said that their PC were set in their own rooms. 57.9% of the subject answered they experienced the Internet Communications. 68.6% of the subject said that they tried PC communications once or twice in a week. 38.5% of the subject expressed that they used their own PC for 1-2 hours in a day. Most of them(82.7%) enjoyed the PC games or entertainment programs. 81.3% of the subject answered that their school performance didn't show the progress after the use of their own PC. 78.3% of the subject answered that they acquired information. 45.2% of the subject answered that they made their friend through the Internet communications. 78.7% of the subject answered that the time of family dialogue decreased. 70.7% of the subject answered that the time of their TV watching decreased. 3. As for their post-exposure reactions the subject who were exposed to the PC Pornography showed the point 2.93 in the item 'pleasure'. The point of 'sexual impulses' was 2.81. But the point of 'anxiety' was 2.75, the point of 'dislike or disgust' was 2.62, the point of 'guilty' was 2.59. 4. According to the frequency, the motivation and the companionship on the exposure to PC Pornography, their post-exposure reaction scores showed differences significantly. Finally, the post-exposure reaction had relation to the frequency, the motivation, the companionship and the place (F=3.28 ~ 8.40, p=.012 ~ .000).

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