• Investigative Magnetic Resonance Imaging
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• v.25 no.2
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• pp.118-128
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• 2021

Purpose: To investigate the value of MR textural analysis, including use of diffusion-weighted imaging (DWI) to differentiate malignant from benign soft-tissue tumors on 3T MRI. Materials and Methods: We enrolled 69 patients (25 men, 44 women, ages 18 to 84 years) with pathologically confirmed soft-tissue tumors (29 benign, 40 malignant) who underwent pre-treatment 3T-MRI. We calculated MR texture, including mean, standard deviation (SD), skewness, kurtosis, mean of positive pixels (MPP), and entropy, according to different spatial-scale factors (SSF, 0, 2, 4, 6) on axial T1- and T2-weighted images (T1WI, T2WI), contrast-enhanced T1WI (CE-T1WI), high b-value DWI (800 sec/mm²), and apparent diffusion coefficient (ADC) map. We used the Mann-Whitney U test, logistic regression, and area under the receiver operating characteristic curve (AUC) for statistical analysis. Results: Malignant soft-tissue tumors had significantly lower mean values of DWI, ADC, T2WI and CE-T1WI, MPP of ADC, and CE-T1WI, but significantly higher kurtosis of DWI, T1WI, and CE-T1WI, and entropy of DWI, ADC, and T2WI than did benign tumors (P < 0.050). In multivariate logistic regression, the mean ADC value (SSF, 6) and kurtosis of CE-T1WI (SSF, 4) were independently associated with malignancy (P ≤ 0.009). A multivariate model of MR features worked well for diagnosis of malignant soft-tissue tumors (AUC, 0.909). Conclusion: Accurate diagnosis could be obtained using MR textural analysis with DWI and CE-T1WI in differentiating benign from malignant soft-tissue tumors.

• Journal of Korean Society of Water and Wastewater
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• v.19 no.6
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• pp.819-826
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• 2005

To guarantee the disinfection ability in clearwell, a value of CT is considered where C[mg/l] is disinfectant residual at the exit of clearwell and T[min] means $T_{10}$, the contact time when 10% of tracer is out of clearwell after introducing the tracer at the inlet. To meet a CT value required, increasing the C value is not recommended because high C value can increase potential of producing disinfection by product like THMs. Increasing the hydraulic efficiency surrogated by $T_{10}$ is thus an option widely recommended. Right now, it is widely adopted estimating $T_{10}$ considering LW ratio only due to the suggestions of previous researches. The authors think however there are other factors to consider including shape, flow rate, configuration of inlet and outlet, and the existence of intra basin. This study is initiated to closely look at the effects of two factor on hydraulic efficiency. The factors are shape and inlet flow velocity, i.e., inflow. For that, computational fluid dynamics (CFD) model is developed and pilot test is also carried out. The results show that at a L/W ratio, disinfection ability is overestimated with larger length in shape and higher inlet flow velocity. This suggests that in determining $T_{10}$, the shapes of clearwell and inlet flow velocity should also be considered as well as L/W ratio.

• Journal of the Korean Society of Radiology
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• v.83 no.6
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• pp.1312-1326
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• 2022

Purpose To investigate the added value of right down decubitus (RDD) CT when determining adjacent organ invasion in cases of advanced gastric cancer (AGC). Materials and Methods A total of 728 patients with pathologically confirmed T4a (pT4a), surgically confirmed T4b (sT4b), or pathologically confirmed T4b (pT4b) AGCs who underwent dedicated stomach-protocol CT, including imaging of the left posterior oblique (LPO) and RDD positions, were included in this study. Two radiologists scored the T stage of AGCs using a 5-point scale on LPO CT with and without RDD CT at 2-week intervals and recorded the presence of "sliding sign" in the tumors and adjacent organs and compared its incidence of appearance. Results A total of 564 patients (77.4%) were diagnosed with pT4a, whereas 65 (8.9%) and 99 (13.6%) patients were diagnosed with pT4b and sT4b, respectively. When RDD CT was performed additionally, both reviewers deemed that the area under the curve (AUC) for differentiating T4b from T4a increased (p < 0.001). According to both reviewers, the AUC for differentiating T4b with pancreatic invasion from T4a increased in the subgroup analysis (p < 0.050). Interobserver agreement improved from fair to moderate (weighted kappa value, 0.296-0.444). Conclusion RDD CT provides additional value compared to LPO CT images alone for determining adjacent organ invasion in patients with AGC due to their increased AUC values and improved interobserver agreement.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.20
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• pp.8725-8734
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• 2014

The transforming growth factor-${\beta}1$ (TGF-${\beta}1$) gene 29 T/C polymorphism is thought to be associated with breast cancer risk. However, reports are largely conflicting and underpowered. We therefore conducted a meta-analysis of all available case-control studies relating the TGF-${\beta}1$ 29T/C polymorphism to the risk of developing breast cancer by including a total of 31 articles involving 24,021 cases and 31,820 controls. Pooled ORs were generated for the allele contrasts, with additive genetic, dominant genetic and recessive genetic models. Subgroup analysis was also performed by ethnicity for the TGF-${\beta}1$ 29T/C polymorphism. No association was found in the overall analysis (C vs T: OR=1.028, 95% CI=0.949-1.114, p-value 0.500; CC vs TC: OR= 1.022, 95% CI=0.963-1.085, p-value 0.478; CC vs TT: OR= 1.054, 95% CI=0.898-1.236, p-value 0.522; CC vs TT+ TC: OR= 1.031, 95% CI=0.946-1.124, p-value 0.482; TT vs CC+TC: OR= 0.945, 95% CI=0.827-1.080, p-value 0.403). Similarly, in the subgroup analysis by ethnicity, no association was found in Caucasian (C vs T: OR= 1.041, 95% CI=0.932-1.162, p-value 0.475; CC vs TC: OR= 1.031, 95% CI=0.951-1.118, p-value 0.464; CC vs TT: OR= 1.081, 95% CI=0.865-1.351, p-value 0.493; CC vs TT+TC: OR= 1.047, 95% CI=0.929-1.180, p-value 0.453; TT vs CC+TC: OR= 0.929, 95% CI=0.775-1.114, p-value 0.429;) and Asian populations (C vs T: OR= 1.004, 95% CI=0.908-1.111, p-value 0.931; CC vs TC: OR= 0.991, 95% CI=0.896-1.097, p-value 0.865; CC vs TT: OR= 1.015, 95% CI=0.848-1.214, p-value 0.871; CC vs TT+TC: OR= 1.000, 95% CI=0.909-1.101, p-value 0.994; TT vs CC+TC: OR= 0.967, 95% CI=0.808-1.159, p-value 0.720;). No evidence of publication bias was detected during the analysis. No significant association with breast cancer risk was demonstrated overall or on subgroup (Caucasian and Asian) analysis. It can be concluded that TGF-${\beta}1$ 29T/C polymorphism does not play a role in breast cancer susceptibility in overall or ethnicity-specific manner.

• Journal of The Korean Society of Grassland and Forage Science
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• v.29 no.3
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• pp.217-226
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• 2009

This study was carried out to investigate the effects of collection time on the physical characteristics, Nutritive value, digestibility and palatability in rice straw. Collection time of rice straw after the rice harvest was allocated into nine treatments: T1 (10 days), T2 (25 days), T3 (40 days), T4 (55 days), T5 (70 days), T6 (85 days), T7 (100 days), T8 (115 days) and T9 (130 days). The results are summarized as follow: Plant length, leaf length and green degree were decreased with prolonging collection time. Mold distribution and dry matter loss were increased with prolonging collection time. Crude protein and crude fat were decreased with prolonging collection time, crude fiber were increased with prolonging collection time. But crude ash showed multifarious. In situ dry matter digestibility was decreased with prolonging collection time. Palatability of Hanwoo, Holstein and deer was decreased with prolonging collection time. The results of this study indicate that good rice straw collection time would be recommendable during the from 10 days to 40 days after rice straw harvest.

• Journal of applied mathematics & informatics
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• v.29 no.5_6
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• pp.1541-1547
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• 2011

In this paper, using B.Ricceri's three critical points theorem, we prove the existence of at least three classical solutions for the problem $$\{u^{(4)}(t)={\lambda}f(t,\;u(t)),\;t{\in}(0,\;1),\\u(0)=u(1)=u^{\prime}(0)=u^{\prime}(1)=0,$$ under appropriate hypotheses.

• Bulletin of the Korean Mathematical Society
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• v.47 no.2
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• pp.411-422
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• 2010

By using the fixed point index theory, we investigate the existence of at least two positive solutions for p-Laplace equation with sign-changing nonlinear terms $(\varphi_p(u'))'+a(t)f(t,u(t),u'(t))=0$, subject to some boundary conditions. As an application, we also give an example to illustrate our results.

• Food Science of Animal Resources
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• v.38 no.6
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• pp.1203-1215
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• 2018

The antioxidant effects of Allium hookeri root (AHR) were investigated by evaluating lipid and protein oxidation in meatballs during refrigerated storage at $4{\pm}1^{\circ}C$. AHR was mixed at concentrations of 0.5% (w/w, T2) and 1% (w/w, T3) with minced longissimus dorsi muscle. Meatballs containing AHR (T2 and T3) were compared to those containing 0.05% (w/w) ascorbic acid (T1) as a reference and without antioxidant as a control. The 2-thiobarbituric acid reactive substances (TBARS) value, disulfide bond formation, carbonyl contents, and volatile basic nitrogen (VBN) value of T2 were lower than those of the control during storage (p<0.05). The pH values of T2 and T3 were higher than that of the control (p<0.05). Texture profile analysis of T2 revealed a lower value compared to the control (p<0.05). Therefore, the VBN value, TBARS value, disulfide bond formation, and carbonyl content in meatball containing AHR were lower than those of the control meatball. These results indicate that AHR improves the quality of meat products and functions as an antioxidant.

• Journal of the Korean Society of Food Culture
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• v.25 no.1
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• pp.36-46
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• 2010

The purpose of this study was to investigate the effects of servicescapes in Korean restaurants on customers' experiential value, pleasure feeling and customer satisfaction. Based on a total of 550 samples obtained from empirical research, this study reviewed the reliability and fitness of research model using the Amos program. The relationships hypothesized in the model were tested simultaneously by using a structural equation model (SEM). The proposed model provided an adequate fit to the data, $\chi^2=406.097$ (df 130), p<.001, GFI .915, AGFI .889, RMR .042, NFI .955, CFI .969, RMSEA .062. SEM results showed that the servicescape showed a positive significant effect on customers' experiential value ($\beta=.808$, t=15.171, p<.001), and customers' experiential value had a positive significant effect on pleasure feeling ($\beta=.756$, t=10.616, p<.001). Also, customer's experiential value ($\beta=.391$, t=8.579, p<.001) and pleasure feeling ($\beta=.573$, t=13.091, p<.001) had a positive significant effects on customer satisfaction. Analysis of mediating roles showed that, the effect of servicescapes in Korean restaurants on customers' pleasure feeling was perfectly mediated by the customers' experiential value. Limitations of this study and future research directions are also discussed.

• Culinary science and hospitality research
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• v.18 no.5
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• pp.1-15
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• 2012

This study analyzed the influence of the quality of medicinal food on perceived values, repurchase intention and recommendation intention. The objective of this study is to suggest the efficient operating direction for specialized medicinal food restaurants to grow as an axis of the food service industry by showing the future direction of medicinal food and establishing marketing strategies to maintain/secure customers. From June 15th to July 2nd, 2009, the survey was conducted for the customers of medicinal food restaurants, located in Seoul and Gyeonggi-do. After distributing 250 copies of questionnaire, 195 of them were collected and total 192 were used for the analysis after excluding three copies due to lack of showing sincerity. The analysis results of this study can be summarized as follows. First, the quality of medicinal food was found to have a significant influence on 'functional value(t=5.519)' while having no influence on 'social value.' Second, the 'nutritional quality' of medicinal food was analyzed as having a significant influence on 'social value(t=10.954)' and 'functional value'(t=8.237).' Third, the 'medicinal quality' of medicinal food was analyzed as having no significant influence on 'social value(t=1.191)' and 'functional value(t=0.022).' Fourth, it was found that 'social value' had a significant influence on repurchase intention(t=9.743) and recommendation intention(t=9.154). Fifth, the functional value was analyzed as having a significant influence on repurchase intention(t=7.895) and recommendation intention(t=8.143). The results of the empirical analysis shown in this study properly support the theoretical standard system to achieve successful performance and useful information necessary for systematic operation of specialized medicinal food restaurants.