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Ebstein`s anomaly ; St. Jude Medical valve replacement using partial artificial annulus formation - A Case Report - (Ebstein 기형에 인공판윤을 이용한 금속형 St. Jude Medical 인공판막 대치술)

  • Lee, Jong-Guk;Jo, Jae-Min
    • Journal of Chest Surgery
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    • v.25 no.8
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    • pp.826-831
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    • 1992
  • Ebstein`s anomaly is characterized by a downward displacement of a malformed tricuspid valve, The ideal surgical management of Ebstein`s anomaly is not yet established. Recently we experience one case of Ebstein`s anomaly, which was treated sussessfully by partial artificial annulus formation, and tricuspid valve replacement with St. Jude Medical valve. We have achieved excellent results with mechanical valve replacement and partial artificial annulus formation using wessex pericardial patch. On follow up for 4 years, the patient is well and in functional class I.

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Building safe communities: A dynamic simulation study

  • Cho, Sung-Sook;Gillespie David F.;Robards Karen Joseph
    • Korean System Dynamics Review
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    • v.7 no.1
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    • pp.213-228
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    • 2006
  • This paper reports the results of a study designed to understand and facilitate disaster mitigation for communities located in low frequency/high magnitude earthquake zones. The study is based on a small town located near the New Madrid Fault Zone and is therefore at significant earthquake risk. A system dynamics model describes the variables and policies governing the distribution of building safety over time. Data from this town is used to establish a 25-year baseline. Simulations are run to demonstrate the consequences of different building policies.

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Immune Responses of BALB/c Mice Administrated via Oral Route to a Combined Salmonella Typhimurium Ghost Vaccine (복합 살모넬라 타이피무리움 고스트 백신의 마우스 구강 투여에 의한 면역 응답)

  • Kim, Pan Gil;Ha, Yeon Jo;Lee, Su Man;Kim, Sam Woong;Gal, Sang Wan
    • Journal of Life Science
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    • v.25 no.11
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    • pp.1197-1203
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    • 2015
  • Salmonella Typhimurium (ST) JOL389 and χ3339 are strong virulent strains against mouse. ST χ8554 is derived by deletion of the asd gene from ST χ3339. Plasmid pMMP184 carrying a ghost cassette was transformed into ST χ8554, and ST χ8554 ghost cells were prepared and administrated via the oral route to BALB/c mice. Change in the amount of total IgG was not elicited to boosting of single ST χ8554 ghost cells, but the content was increased from 6 weeks after the 3rd administration. However, when the ST JOL389 ghost cells is administered together with ST χ8554 ghost cells, the content of total IgG was increased in 2 weeks post primary administration. It was found that the content of total IgG of the group mixed with ST JOL389 ghost cells showed an increased value of 8 times or more at 10 weeks when compared with the group of ST χ8554 ghost cells. The content of IgG1, IgG2a, and sIgA in both groups increased from 4 weeks postprimary administration. As a challenge test of virulent ST χ3339, χ8554 (pMMP184) and χ8554 (pMMP184)/JOL389 ghost cell groups showed protection of 50% or more when compared to the control group. These results suggest that the preparation of combined ghost cells from a strong virulent ST increases immunity more than a single strain.

Species Composition of Benthic Macroinvertebrates and Water Evaluation Using Their Species in the Songji River in Korea (한국 송지천에서 저서성대형무척추동물의 종조성과 이를 이용한 수질 평가)

  • Lee, Byeong Ryong;Huh, Man Kyu
    • Journal of Life Science
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    • v.29 no.5
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    • pp.580-587
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    • 2019
  • Benthic macroinvertebrates were analyzed in March, June, September, and December 2018 to evaluate water quality in the Songji River in Sacheon-ci, Korea. The identified benthic macroinvertebrates included 447 individuals belonging to 20 species, 18 families, 12 orders, 5 classes, and 3 phyla. Various ecological parameters were estimated for evaluation of the river status. The total ecological score of benthic macroinvertebrate community (TESB) varied from 17 (Station D) to 41 (Station A). The saprobic index and ecological score of benthic macroinvertebrate community (ESB) for the evaluation of river status revealed a water quality evaluation at Station A of II (oligosaprobic), indicating some satisfactory water protection. The benthic macroinvertebrate index (BMI) varied from 25.207 (Site C) to 39.348 (Station A). The evaluation of the river status at Stations C and D was polysaprobic, and sensitive taxa were absent. The mean Shannon-Weaver index (H') of diversity varied from 1.288 (Station D) to 2.250 (Station A). The classification of saprobity based on H' was ${\beta}$-mesosaprobic at Station A and ${\alpha}$-mesosaprobic at the other stations. The value of geometric density was varied from 1.229 (Station A) to 2.071 (Station D), with a mean of 1.582. An artificial load is being added to this river. One of load is the rectal river construction which flows straight through the river physics. Thus, the environment of living organisms deteriorates due to insufficient water. In order to secure the quality of the Songji River and a good environmental habitat, several low-height stepped-beam structures are required.

A RADIOGRAPHIC STUDY OF MENTAL FORAMEN IN INTRAORAL RADIOGRAPHS (구내방사선사진상의 이공에 관한 연구)

  • Sohn Jeong-Ick;Choi Karp-Shik
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.25 no.2
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    • pp.501-511
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    • 1995
  • The purpose of this study was to evaluate the position and shape of mental foramen in periapical radiographs. For this study, periapical radiographs of premolar areas were obtained from the 200 adults. Accordingly, the positional and shape changes of mental foramen were evaluated. The authors obtained radiographs according to changes in radiation beam direction in periapical radiographs of premolar areas, and then evaluated the positional and shape changes of mental foramen. The following results were obtained: 1. Shapes of mental foramen were observed elliptical(34.3%), round or oval(28.0%), unidentified(25.5%) and diffuse(12.2%) type in descending order of frequency. 2. Horizontal positions of mental foramen were most frequently observed at the 2nd premolar area(55.3%), the area between the 1st premolar and 2nd premolar(39.6%), the area between the 2nd premolar and 1st molar(3.4%), the 1st premolar area(1.0%), the area between the canine and 1st premolar(0.7%) in descending order of frequency. 3. Vertical positions of mental foramen were most frequently observed at the inferior to apex(67.1%), and at apex(24.8%), overlap with apex(6.4%), superior to apex(1.7%) in descending order of frequency. 4. Shapes of mental foramen were more obviously observed at the upward 10° positioned periapical radiographs. And according to the changes of horizontal and vertical position, they were observed similar to normally positioned periapical radiographs.

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The Evaluation of Drug Utilization Review on Potentially Inappropriate Medications for Elderly Patients in a Tertiary Hospital (Drug Utilization Review 시행 전후 3차 의료기관에서의 노인주의약품 외래처방 현황 분석)

  • Cho, Yeo Hyang;Kim, Kwang Joon
    • Korean Journal of Clinical Pharmacy
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    • v.29 no.1
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    • pp.25-32
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    • 2019
  • Objective: South Korea made a list of potentially inappropriate medications (PIMs) for elderly patients in 2015 and has prompted medical professionals to prescribe proper medication by using the drug utilization review (DUR) system. It has been three years since the system was introduced, but related studies have rarely been conducted. This study aimed to evaluate the effect of the DUR system on the prescription of PIMs for elderly patients. Methods: The data on the prescription of PIMs for elderly patients (${\geq}65$ years) who received medical treatment between March 1st and May 31st in 2015 (before introduction of the DUR system) and who received medical treatment between March 1st and May 31st in 2018 (after introduction of the DUR system) were retrospectively collected from electronic medical records. Results: The prescriptions of PIMs decreased from 3,716 (7.7%) to 3,857 (6.9%) (p < 0.001). The prescription of escitalopram and paroxetine, among selective serotonin reuptake inhibitors, increased significantly, and that of short-acting benzodiazepines also increased significantly from 454 (0.93%) to 624 (1.2%). Conclusion: Prescription of PIMs for elderly patients significantly decreased (p < 0.001) after the DUR system was introduced. Further expanded studies of PIMs need to be conducted for the safety of elderly patients.

Variant angina diagnosed on pre-hospital 12-lead electrocardiogram: A case report (병원 전 12-Lead ECG 측정을 통해 진단된 이형성 협심증 1례)

  • Kim, Ji-Won;Ki, Eunyoung
    • The Korean Journal of Emergency Medical Services
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    • v.25 no.1
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    • pp.243-249
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    • 2021
  • A decrease in coronary blood flow leads to an imbalance between the supply of oxygen to the myocardium and its demand, and reversible or irreversible damage to the myocardium could occur depending on the severity of the resultant ischemia and the duration of the imbalance. This imbalance results in a cascade of ischemic reactions in the following order: metabolic abnormalities, diastolic dysfunction, systolic dysfunction, and electrocardiogram changes. Variant angina is caused by the closure of the coronary artery due to reversible coronary artery spasm, resulting in myocardial ischemia and subsequent chest pain as a clinical symptom. Variant angina may be observed as ST segment elevation in electrocardiogram measured when present in chest pain. However, 12-lead electrocardiogram performed after the patient's chest pain resolves does not help in the diagnosis. Since the duration of chest pain appears to be <15 minutes, it is important to perform the 12-lead electrocardiogram when clinical symptoms are present. If nitroglycerin is administered without performing 12-lead electrocardiogram by 119 pre-hospital paramedics, the chest pain would be resolved, making it impossible to identify changes in the ST segment. Before administration of nitroglycerin, changes in the ST segment must be recorded by performing 12-lead electrocardiogram.

Direction Finding and Tracking using Single-Ring Circular Array Antenna and Space Division Table (단원형배열안테나와 공간분할테이블을 이용한 방향탐지 및 추적)

  • Park, Hyeongyu;Woo, Daewoong;Kim, Jaesik;Park, Jinsung
    • Journal of the Korea Institute of Military Science and Technology
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    • v.25 no.2
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    • pp.117-124
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    • 2022
  • Single-ring circular array antennas can be applied to direction finding systems in order to use nose-section in other purposes, and the interferometry is a proper direction finding method to those systems. We usually make the interferometer baseline long enough to achieve good angular accuracy. However, an interferometer with baseline longer than a half-wavelength has the ambiguity problem. In this paper, we present a novel method for solving the ambiguity problem in interferometry systems. This technique is based on the amplitude comparison method and the space division table, and it can place a target within the angular region in which the ambiguity problem does not occur by roughly estimating direction-of-arrival. The Monte Carlo simulation results show that proposed method can effectively remove the ambiguity problem in the system.