• Journal of the Korean Society of Food Science and Nutrition
• /
• v.37 no.1
• /
• pp.1-7
• /
• 2008

The antioxidative, antimutagenic and cytotoxic activities of ethanol extract from Cornus officianalis have been studied. The antioxidant activity of the ethanol extract was measured by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The inhibition effects on the mutagenicity in Salmonella Typhimurium TA100 were evaluated by Ames test and cancer cell inhibitory effects in Hep3B cell and HeLa cell were tested by MTT assay. Cornus officianalis had an important free radical-scavenging activity towards the DPPH radical. At a concentration of 500 ppm, the DPPH radical-scavenging activity of Cornus officianalis was similar to that of L-ascorbic acid. None of the extracts produced a mutagenic effect on S. Typhimurium TA100. The ethanol extract from Cornus officianalis showed about 77% of inhibition at 500 ppm on the mutagenicity induced by 4-nitroquinoline-1-oxide. The extract from Cornus officianalis showed strong cytotoxicity against Hep3B and HeLa cells, with inhibition of 83 and 78% at a dose of $700{\mu}g$/plate, respectively. Moreover, the ethanol extracts had 34.33 mg H.E/g of polyphenols and 5.67 mg Q.E/g of flavonoids, respectively. Therefore, the present study showed antioxidative, antimutagenic and anticancer potential of the ethanol extract from Cornus officianalis.

• Journal of Korean Society of Forest Science
• /
• v.104 no.4
• /
• pp.519-526
• /
• 2015

This study was investigated to analyze stand structure in Daegu Dodong T.orientalis Forest for conservation Thuja orientalis forest. Results of cluster analysis, it was classified to Quercus variabilis group(A), Quercus variabilis-Quercus mongolica group(B), Pinus densiflora group(C), Thuja orientalis group(D). Charaters of location environments for D group were analyzed that altitude 99.3 m, slope $59^{\circ}$, rock exposure 68.3%, BHA $21.8m^2/ha$ and North West aspects. The MRPP-test, It classified groups, appropriately. Importance value of D group was T. orientalis 85.42, Q. variabilis 1.28, P.densiflora 1.30, Fraxinus rhynchophylla 3.56 etc. DBH classes of D group were expressed inverted-J-shaped curve. H' was resulted in 0.600~0.834, H'max 1.317~1.466, J' 0.456~0.594, D' 0.405~0.544. Indecator species Analysis were conducted that woody plants were 4 taxa, Herbal plants 9 taxa.

• Journal of Ginseng Research
• /
• v.42 no.4
• /
• pp.485-495
• /
• 2018

Background: The geographical origin of Panax ginseng Meyer, a valuable medicinal plant, is important to both ginseng producers and consumers in the context of economic profit and human health benefits. We, therefore, aimed to discriminate between the cultivation regions of ginseng using the stable isotope ratios of C, N, O, and S, which are abundant bioelements in living organisms. Methods: Six Korean ginseng cultivars (3-yr-old roots) were collected from five different regions in Korea. The C, N, O, and S stable isotope ratios in ginseng roots were measured by isotope ratio mass spectrometry, and then these isotope ratio profiles were statistically analyzed using chemometrics. Results: The various isotope ratios found in P. ginseng roots were significantly influenced by region, cultivar, and the interactions between these two factors ($p{\leq}0.001$). The variation in ${\delta}^{15}N$ and ${\delta}^{13}C$ in ginseng roots was significant for discriminating between different ginseng cultivation regions, and ${\delta}^{18}O$ and ${\delta}^{34}S$ were also affected by both altitude and proximity to coastal areas. Chemometric model results tested in this study provided discrimination between the majority of different cultivation regions. Based on the external validation, this chemometric model also showed good model performance ($R^2=0.853$ and $Q^2=0.738$). Conclusion: Our case study elucidates the variation of C, N, O, and S stable isotope ratios in ginseng root depending on cultivation region. Hence, the analysis of stable isotope ratios is a suitable tool for discrimination between the regional origins of ginseng samples from Korea, with potential application to other countries.

• Bulletin of the Korean Chemical Society
• /
• v.31 no.6
• /
• pp.1519-1526
• /
• 2010

The behavior of peptide or protein solutes in saline aqueous solution is a fundamental topic in physical chemistry. Addition of ions can strongly alter the thermodynamic and physical properties of peptide molecules in solution. In order to study the effects of added ionic salts on protein conformation and dynamics, we have used the molecular dynamics (MD) simulations to investigate the behavior of Staphylococcus aureus Hfq protein under two different ionic concentrations: 0.1 M NaCl and 1.0 M NaCl in presence and absence of RNA (a hepta-oligoribonucleotide AU5G). Hfq, a global regulator of gene expression is highly conserved and abundant RNA-binding protein. It is already reported that in vivo the increase of ionic strength results in a drastic reduction of Hfq affinity for $Q{\beta}$ RNA and reduces the tendency of aggregation of Escherichia coli host factor hexamers. Our results revealed the crucial role of 0.1 M NaCl Hfq system on the bases with strong hydrogen bonding interactions and by stabilizing the aromatic stacking of Tyr42 residue of the adjacent subunits/monomers with the adenine and uridine nucleobases. An increase in RNA pore diameter and weakened compactness of the Hfq-RNA complex was clearly observed in 1.0 M NaCl Hfq system with bound RNA. Aggregation of monomers in Hfq and the interaction of Hfq with RNA are greatly affected due to the presence of high ionic strength. Higher the ionic concentration, weaker is the aggregation and interaction. Our results were compatible with the experimental data and this is the first theoretical report for the experimental study done in 1980 by Uhlenbeck group for the present system.

• Journal of the Korea Concrete Institute
• /
• v.24 no.2
• /
• pp.137-145
• /
• 2012

Strength model for blasted furnace slag mortar blended with sodium was investigated in this study. The main parameters of AAS (alkali activated slag) mortar were dosage of alkali activator, water to binder ratio (W/B), and aggregate to binder ratio (A/B). For evaluating the property related to the dosage of alkali activator, sodium carbonate ($Na_2CO_3$) of 4~8% was added to 4% dosage of sodium hydroxide (NaOH). W/B and A/B was varied 0.45~0.60 and 2.05~2.85, respectively. An alkali quality coefficient combining the amounts of main compositions of source materials and sodium oxide ($Na_2O$) in sodium hydroxide and sodium carbonate is proposed to assess the compressive strength of alkali activated mortars. Test results clearly showed that the compressive strength development of alkali-activated mortars were significantly dependent on the proposed alkali quality coefficient. Compressive strength development of AAS mortars were also estimated using the formula specified in the previous study, which was calibrated using the collected database. Predictions from the simplified equations showed good agreements with the test results.

• Journal of the Korean Data and Information Science Society
• /
• v.27 no.5
• /
• pp.1375-1387
• /
• 2016

The purpose of this study was to evaluate the effect of exercise on cognitive function in the elderly through a systematic literature review and meta-analysis. For the study purpose, 14 studies were selected through a systematic process of using several databases and 11 studies were used to estimate the effect size of exercise on cognitive function. Meta-analysis was performed using a random effects model, and the effect size on cognitive function was calculated. The effect size for cognitive function of exercise intervention was Hedges' g=1.05 (95% CI: 0.61~1.50), indicating a large effect size. For heterogeneity, moderator analysis was performed using intervention, number of times per week, intervention duration, and cognitive function measurement. Cognitive function measurement was statistically significant, the other moderators did not significant difference. Results support that exercise has significant positive effects on cognitive function in elderly in korea. It also provided a basis that can be applied to exercise intervention design for cognitive function.

• The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
• /
• v.5 no.4
• /
• pp.3-17
• /
• 1994

The error probability of QPSK and DPSK signals with diversity reception technique in m-distribution fading plus impulsive noise environments has been derived and the error probability is evaluated and compared with that in Gaussian noise environment. The error performance degrades as impulsive noise becomes strong and degree of degradation of signal performance in QDPSK signal is larger than that in QPSK signal. The diversity reception technique can improve the error performance not only in fading plus Gaussian noise environment but in fading plus impulsive noise environment. When diversity reception technique is used, the improvement of error performance attains about 10dB to 15dB in terms of CNR as compared with that in non diversity reception. Among diversity techniques the maximal ratio combining is must effective. When diversity reception and coding techniques are used together in impulsive noise plus Rayleigh fading environments, the improvement of error performance attains about 12dB to 15dB in terms of CNR as compared with that of only diversity reception technique case and the improvement of error perform- ance in RS coding attains about 2dB in terms of CNR as compared with that of BCH coding case.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.18 no.7
• /
• pp.1557-1564
• /
• 2014

In this paper, we propose a signal detection technique based on the parallel orthogonal matching pursuit (POMP) is proposed for generalized shift space keying (GSSK) systems, which is a modified version of the orthogonal matching pursuit (OMP) that is widely used as a greedy algorithm for sparse signal recovery. The signal recovery problem in the GSSK systems is similar to that in the compressed sensing (CS). In the proposed POMP technique, multiple indexes which have the maximum correlation between the received signal and the channel matrix are selected at the first iteration, while a single index is selected in the OMP algorithm. Finally, the index yielding the minimum residual between the received signal and the M recovered signals is selected as an estimate of the original transmitted signal. POMP with Quantization (POMP-Q) is also proposed, which combines the POMP technique with the signal quantization at each iteration. The proposed POMP technique induces the computational complexity M times, compared with the OMP, but the performance of the signal recovery significantly outperform the conventional OMP algorithm.

• The KIPS Transactions:PartB
• /
• v.14B no.5
• /
• pp.329-336
• /
• 2007

In this paper we propose both the construction of image DB including information on the shooting location and direction of the captured outdoor images and the efficient retrieval method from the DB. Furthermore, for the automatic extraction of the location and direction information, we suggest to have the Digital Camera equipped with an expandable GPS modulo which has a function to calculate the location and direction and also to utilize GPS IFD tags in the EXIF. Then that will make it possible for us to retrieve quickly and precisely the target image with its geography and other objects on the ground included. In the previous retrieval method based only on the location, we eel some extra useless images due to the fact that all the images in the ROI(Region Of Interest) are searched on one condition, radius. However, with the proposed method in this paper, we can not only retrieve all the images selectively within the ROI but also achieve nearly 100% of precision when we search for the target images within DOI(Direction Of Interest) with another condition, direction, added. Applying this method to an image retrieval system, we can classify or retrieve natural images based on the location and direction information, which, in turn, will be vitally useful to diverse industrial fields such as disaster alarm system, fire and disaster prevention system, traffic information system, and so forth.

• Korean Journal of Biological Psychiatry
• /
• v.13 no.4
• /
• pp.260-266
• /
• 2006

Objectives : Synapsin III near VCFS region on chromosome 22q affects. It could be an interesting candidate gene for schizophrenia. D22S280 is a highly polymorphic genetic marker residing in synapsin III. We examined association of D22S280 marker on synapsin III with Korean patients with schizophrenia. Methods : The subjects were 46 male Korean patients with schizophrenia and 60 male normal controls. Using polymerase chain reaction, gel electrophoresis, ABI 310 genetic analyzer, and GeneScan Collection 3.1 software, we confirmed genotypes of D22S280 marker. We examined Hardy-Weinberg equilibrium and case-control association using SAS/Genetic 9.1.3. Results : Genotypes of both schizophrenia and control groups were in Hardy-Weinberg equilibrium. We could not find any significant statistical differences in allele-wise(${\chi}^2$=10.4, df=6, p=0.098) and genotype-wise (${\chi}^2$=22.1 df=19, p=0.258) analyses of D22S280 marker between schizophrenia and normal controls. Individual allele analyses with df=1 showed significant differences in A1(p=0.025) and A7(p=0.034) allele, which were not significant following Bonferroni corrections(A1:p=0.177, A7:p=0.235). Conclusion : We couldn't find any association between schizophrenia and the synapsin III gene. Given the small number of subjects studied, further investigations are needed.