• Title/Summary/Keyword: $D^*$criterion

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Review of Economic Evaluation Studies for Drug Reimbursement Decision (의약품 보험급여 결정을 위한 경제성평가 연구의 평가)

  • Choi Sang-Eun;Sullivan Sean D.
    • Health Policy and Management
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    • v.15 no.4
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    • pp.1-25
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    • 2005
  • Legislation on pharmaceutical reimbursement decision using economic evaluation results was made in Korea in fm, but has yet to be fully implemented. We evaluated the quality of Korean economic evaluation studies of pharmaceuticals to understand gaps between legislation and implementation. From this evaluation, we propose policy options that might strengthen the research Infrastructure In order to support such studies. We reviewed 23 published studies for drugs conducted between 1996 and 2004. Evaluation criteria included methodological characteristics, healthcare system characteristics, population characteristics, and applicability of results. Large variation in study quality was observed, particularly with study design, outcome data, treatment patterns and interpretation. Korean clinical data used was mostly from observational studies of 1-2 hospitals. Foreign data was extracted from clinical trials that did not Include Asian population and their selection criterion was not clarified. With respect to treatment patterns, medical records and hospital bills were used without adjustment regarding area, hospital type, and others. And next frequent situation relied on expert opinion from academic physicians in specialty practice. preference measures, when used, were not elicited from the Korean population. $78.3\%$ of studies did not clarify the funding source. If the Korean economic evaluation policy is to provide meaningful data for decision makers, the quality of cost-effectiveness studies will need to improve dramatically. This may involve access to or creation of better data, more diverse funding, unproved training of researchers and evaluators, and partnerships with technology manufacturers.

Process Design for Large-Scale Ring-Rolling of Ti-6Al-4V Alloy (Ti-6Al-4V 합금의 대형 링 압연공정설계)

  • Yeom, J.T.;Kim, J.H.;Lee, D.G.;Park, N.K.;Choi, S.S.;Lee, C.S.
    • Transactions of Materials Processing
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    • v.16 no.3 s.93
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    • pp.172-177
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    • 2007
  • The process design for large-scale ring rolling of Ti-6Al-4V alloy was performed by calculation method, processing map approach and FEM simulation. The ring rolling design includes geometry design and optimization of process variables. The calculation method was used to make geometry design such as initial billet and blank sizes, and final rolled ring shape. A commercial FEM code, SHAPE-RR was used to simulate the effect of process variables in ring rolling on the distribution of the internal state variables such as strain, strain rate and temperature. In order to predict the forming defects during ring rolling and the formation of over-heating above $\beta$-transus temperature due to deformation heating, the process-map approach based on Ziegler's instability criterion was used with FEM simulation. Finally, an optimum process design to obtain sound Ti-6Al-4V rings without forming defects was suggested through combined approach of Ziegler's instability map and FEM simulation results.

Joint Relay Selection and Power Allocation for Two-way Relay Channels with Asymmetric Traffic Requirements

  • Lou, Sijia;Yang, Longxiang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.7 no.8
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    • pp.1955-1971
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    • 2013
  • This paper studies relay selection and power allocation for amplify-and-forward (AF) based two-way relay networks (TWRN) with asymmetric traffic requirements (ATR). A joint relay selection and power allocation algorithm is proposed to decrease the outage probability of TWRN with ATR. In this algorithm, two sources exchange information with the help of the relay during two time slots. We first calculate the optimal power allocation parameters based on instantaneous channel state information (CSI), and then derive a tight lower bound of outage probability. Furthermore, we propose a simplified relay selection criterion, which can be easily calculated as harmonic mean of instantaneous channel gains, according to the outage probability expressions. Simulation results verified the theoretical analyses we presented. It is shown that the outage probability of our algorithm improves 3-4dB comparing with that of other existing algorithms, and the lower bound is tight comparing with actual value for the entire signal-to-noise ratio (SNR) region.

Channel Estimation Using Virtual Pilot Signal for MIMO-OFDM Systems (MIMO-OFDM 시스템을 위한 가상 기준 신호를 이용한 채널 추정 기법)

  • Seo, Heejin;Park, Sunho;Kim, Jinhong;Shim, Byonghyo
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.27 no.1
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    • pp.27-32
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    • 2016
  • In this paper, we proposed a soft decision-directed channel estimation based on MMSE estimation for MIMO-OFDM system. While the conventional method employs only pilot signals for channel estimation, the proposed algorithm performs channel estimation using pilot and reliable data signals. We also proposed selection criterion among reliable data signal for channel estimation. From numerical simulations, we show that the proposed channel estimator achieves 1 dB performance gain over conventional channel estimators.

Parallel computation for debonding process of externally FRP plated concrete

  • Xu, Tao;Zhang, Yongbin;Liang, Z.Z.;Tang, Chun-An;Zhao, Jian
    • Structural Engineering and Mechanics
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    • v.38 no.6
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    • pp.803-823
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    • 2011
  • In this paper, the three dimensional Parallel Realistic Failure Process Analysis ($RFPA^{3D}$-Parallel) code based on micromechanical model is employed to investigate the bonding behavior in FRP sheet bonded to concrete in single shear test. In the model, the heterogeneity of brittle disordered material at a meso-scale was taken into consideration in order to realistically demonstrate the mechanical characteristics of FRP-to-concrete. Modified Mohr-coulomb strength criterion with tension cut-off, where a stressed element can damage in shear or in tension, was adopted and a stiffness degradation approach was used to simulate the initiation, propagation and growth of microcracks in the model. In addition, a Master-Slave parallel operation control technique was adopted to implement the parallel computation of a large numerical model. Parallel computational results of debonding of FRP-concrete visually reproduce the spatial and temporal debonding failure progression of microcracks in FRP sheet bonded to concrete, which agrees well with the existing testing results in laboratory. The numerical approach in this study provides a useful tool for enhancing our understanding of cracking and debonding failure process and mechanism of FRP-concrete and our ability to predict mechanical performance and reliability of these FRP sheet bonded to concrete structures.

Standard Criterion of VUS for ROC Surface (ROC 곡면에서 VUS의 판단기준)

  • Hong, C.S.;Jung, E.S.;Jung, D.G.
    • The Korean Journal of Applied Statistics
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    • v.26 no.6
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    • pp.977-985
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    • 2013
  • Many situations are classified into more than two categories in real world. In this work, we consider ROC surface and VUS, which are graphical representation methods for classification models with three categories. The standard criteria of AUC for the probability of default based on Basel II is extended to the VUS for ROC surface; therefore, the standardized criteria of VUS for the classification model is proposed. The ranges of AUC, K-S and mean difference statistics corresponding to VUS values for each class of the standard criteria are obtained. The standard criteria of VUS for ROC surface can be established by exploring the relationships of these statistics.

Quantitative Analysis on Voltage Schemes for Reliable Operations of a Floating Gate Type Double Gate Nonvolatile Memory Cell

  • Cho, Seong-Jae;Park, Il-Han;Kim, Tae-Hun;Lee, Jung-Hoon;Lee, Jong-Duk;Shin, Hyung-Cheol;Park, Byung-Gook
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.5 no.3
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    • pp.195-203
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    • 2005
  • Recently, a novel multi-bit nonvolatile memory based on double gate (DG) MOSFET is proposed to overcome the short channel effects and to increase the memory density. We need more complex voltage schemes for DG MOSFET devices. In view of peripheral circuits driving memory cells, one should consider various voltage sources used for several operations. It is one of the key issues to minimize the number of voltage sources. This criterion needs more caution in considering a DG nonvolatile memory cell that inevitably requires more number of events for voltage sources. Therefore figuring out the permissible range of operating bias should be preceded for reliable operation. We found that reliable operation largely depends on the depletion conditions of the silicon channel according to charge amount stored in the floating gates and the negative control gate voltages applied for read operation. We used Silvaco Atlas, a 2D numerical simulation tool as the device simulator.

A Study on Feature-Based Multi-Resolution Modelling - Part I: Effective Zones of Features (특징형상기반 다중해상도 모델링에 관한 연구 - Part I: 특징형상의 유효영역)

  • Lee K.Y.;Lee S.H.
    • Korean Journal of Computational Design and Engineering
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    • v.10 no.6
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    • pp.432-443
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    • 2005
  • Recent three-dimensional feature-based CAD systems based on solid or non-manifold modelling functionality have been widely used for product design in manufacturing companies. When product models associated with features are used in various downstream applications such as analysis, however, simplified and abstracted models at various levels of detail (LODs) are frequently more desirable and useful than the full detailed model. To provide multi-resolution models, the features need to be rearranged according to a criterion that measures the significance of the feature. However, if the features are rearranged, the resulting shape is possibly different from the original because union and subtraction Boolean operations are not commutative. To solve this problem, in this paper, the new concept of the effective zone of a feature is defined and identified using Boolean algebra. By introducing the effective zone, an arbitrary rearrangement of features becomes possible and arbitrary LOD criteria may be selected to suit various applications. Besides, because the effective zone of a feature is independent of the data structure of the model, the multi-resolution modelling algorithm based on the effective zone can be implemented on any 3D CAD system based on conventional solid representations as well as non-manifold topological (NMT) representations.

The Study of Direction Finding Algorithms for Coherent Multiple Signals in Uniform Circular Array (등각원형배열을 고려한 코히어런트 다중신호 방향탐지 기법 연구)

  • Park, Cheol-Sun;Lee, Ho-Joo;Jang, Won
    • Journal of the Korea Institute of Military Science and Technology
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    • v.12 no.1
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    • pp.97-105
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    • 2009
  • In this paper, the performance of AP(Alternating Projection) and EM(Expectation Maximization) algorithms is investigated in terms of detection of multiple signals, resolvability of coherent signals and the efficiency of sensor array processing. The basic idea of these algorithms is utilization of relaxation technique of successive 1D maximization to solve a direction finding problem by maximizing the multidimensional likelihood function. It means that the function is maximized over only for a single parameter while the other parameters are fixed at each step of the iteration. According to simulation results, the algorithms showed good performance for both incoherent and coherent multiple signals. Moreover, some advantages are identified for direction finding with very small samples and fast convergence. The performance of AP algorithm is compared with that of EM using multiple criteria such as the number of sensor, SNR, the number of samples, and convergence speed over uniform circular array. It is resulted AP algorithm is superior to EM overally except for one criterion, convergence speed. Especially, for EM algorithm there is no performance difference between incoherent and coherent case. In conclusion, AP and EM are viable and practical alternatives, which can be applied to a direction under due to the resolvability of multi-path signals, reliable performance and no troublesome eigen-decomposition of the sample-covariance matrix.

Video Error Concealment using Neighboring Motion Vectors (주변의 움직임 벡터를 사용한 비디오 에러 은닉 기법)

  • 임유두;이병욱
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.3C
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    • pp.257-263
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    • 2003
  • Error control and concealment in video communication is becoming increasingly important because transmission errors can cause single or multiple loss of macroblocks in video delivery over unreliable channels such as wireless networks and the internet. This paper describes a temporal error concealment by postprocessing. Lost image blocks are overlapped block motion compensated (OBMC) using median of motion vectors from adjacent blocks at the decoder. The results show a significant improvement over zero motion error concealment and other temporal concealment methods such as Motion Vector Rational Interpolation or Side Match Criterion OBMC by 1.4 to 3.5㏈ gain in PSNR. We present experimental results showing improvements in PSNR and computational complexity.