• Title/Summary/Keyword: $CV_{12}$

Search Result 601, Processing Time 0.025 seconds

Antioxidative and Anti-inflammatory Effects of Aurantii Fructus Immaturus Pharmacopuncture (지각 약침액의 항산화 및 항염증 효과에 관한 연구)

  • Kim, Sung-Jin;Park, Sang-Kyun
    • Korean Journal of Acupuncture
    • /
    • v.27 no.2
    • /
    • pp.13-24
    • /
    • 2010
  • Objectives : Ulcerative colitis is a chronic relapsing inflammatory disease in the gastrointestinal tract. We investigated whether Aurantii fructus immaturus (AFI) pharmacopuncture has antioxidative and anti-inflammatory effects. Methods : in vitro experiments, 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging activity, superoxide dismutase (SOD) activity, prevention on $H_2O_2$-induced cell death in RAW264.7 cell line, DNA fragmentation, and cyclooxygenase-2 mRNA expression induced by lipopolysaccharide (LPS), were analyzed to investigate antioxidative and anti-inflammatory effect of AFI pharmacopuncture. in vivo experiment, a murine model of dextran sulfate sodium (DSS)-induced colitis was used to examine the effect of AFI pharmacopuncture on CV12 at different doses of 5 ${\mu}l$, 0.5 ${\mu}l$, 0.05 ${\mu}l$ for 10 days. Body weight, colon length and macroscopic features were investigated. Results : AFI pharmacopuncture showed DPPH free radical scavenging and SOD active effects in a dose-dependent manner. AFI pharmacopuncture showed a protective effect against $H_2O_2$-induced cell injury and also attenuated LPS-induced COX-2 mRNA expression. In a DSS- induced colitis murine model, however, AFI pharmacopuncture at CV12 had no anti-inflammatory effects. Conclusions : The present results suggest that AFI pharmacopuncture extract may have anti- inflammatory and antioxidative effects in vivo test, but further research on the underlying mechanism is required.

A Case Report of Add-On Traditional Korean Medical Treatments in a Patient with Uncontrolled Type 2 Diabetes Mellitus with Conventional Oral Hypoglycemic Agents (기존의 경구용 혈당강하제로 혈당조절이 불량한 제2형 당뇨병 환자에 대한 한양방 병용 치료 1례)

  • Lee, Hye-Yoon;Jung, Eun-sun;Yun, Youngju;Lee, Sang Yeoup
    • The Journal of Internal Korean Medicine
    • /
    • v.42 no.4
    • /
    • pp.718-726
    • /
    • 2021
  • This study presents a case of add-on traditional Korean medical treatments in a 77-year-old male patient with uncontrolled type 2 diabetes mellitus with conventional oral hypoglycemic agents. Chief complaints were uncontrolled glucose level and weight loss. The patient was treated with electroacupuncture (on ST36, CV4, and CV12), herbal medication, and lifestyle advice. The conventional oral hypoglycemic medications were maintained. After 12 weeks, the glycated hemoglobin A1c (HbA1c) decreased from 11.0% to 8.4%. There were significant abnormalities in the liver function and renal function tests, but no adverse event was reported. Further studies are needed to confirm the findings of this case.

The Literature Study on Etiological Cause, Pathogenesis, Acupuncture and Moxibustion Treatment of Hemafecia (변혈(便血)의 병인병기(病因病耭)와 침구치료(鍼灸治療)에 대한 문헌적 고찰)

  • An, Geun-Hyeong;Lee, Hyun
    • Journal of Haehwa Medicine
    • /
    • v.16 no.1
    • /
    • pp.17-29
    • /
    • 2007
  • Objectives : The purpose of this study is to search acupuncture & moxibustion treatment on hemafecia. Methods : We search thirty-seven oriental medical literatures related to hemafecia and arrange the articles according to the etiological cause, pathogenesis, acupuncture & moxibustion treatment. Results : 1. Hemafecia is mainly caused by intrinsic factors such as inadequate diet, habitual drinking, indiscreet sex and others. 2. Hemafecia is mainly due to the intestinal febrile state, but sometimes due to the infirmity of whole body energy including digestive system. 3. Governor Vessel Meridian, Bladder Meridian, Spleen Meridian and Stomach Meridian are frequently used for acupuncture & moxibustion treatment on hemafecia. 4. B57, GV1 are most frequently used for acupuncture & moxibustion treatment on hemafecia. 5. CV12, CV6, S36 are most frequently used for moxibustion treatment on hemafecia. 6. Acupuncture points are mainly distributed throughout the low back, lower abdomen and lower limb.

  • PDF

Real-time Voltammetric Assay of Cadmium Ions in Plant Tissue and Fish Brain Core

  • Ly, Suw-Young
    • Bulletin of the Korean Chemical Society
    • /
    • v.27 no.10
    • /
    • pp.1613-1617
    • /
    • 2006
  • Optimum analytical conditions for cyclic voltammetry (CV) and square wave (SW) stripping voltammetry were determined using mercury-mixed carbon nanotube paste electrode (PE). The results approached the microgram working ranges of SW: 10.0-80.0 $ugL^{-1}$ and CV: 100-700 $ugL^{-1}$ Cd (II); working conditions of 300-Hz frequency, 100 mV amplitude, 1.6 V accumulation potential, 400 sec accumulation time, and 40 mV increment potential. First, analysis was performed through direct assay of cadmium ions deep into the fishs brain core and plant tissue in real time with a preconcentration time of 400 sec. The relative standard deviation of 10.0 $mgL^{-1}$ Cd (II) observed was 0.064 (n = 12) at optimum conditions. The low detection limit (S/N) was set at 0.6 $ugL^{-1}$ ($5.33{\times}10^{-9}$ M). The methods can be used in direct analysis in vivo or in real-time monitoring of plant tissue.

Studies on the Utilization of $F_1$ Hybrids using Cytoplasmic Sterility in Burley(Nicotiana tabacum L. Cv Burley) Tobacco. (Burly(Nicotiana Tabacum L.Cv Burley)종의 세포질적 웅성불임계통을 이용한 $F_1$ 잡종 이용)

  • 한철수;조천준;김용연;이규상
    • Journal of the Korean Society of Tobacco Science
    • /
    • v.2 no.1
    • /
    • pp.28-37
    • /
    • 1980
  • This experiment was carried out to evaluate the utilization of F, hybrids using cytoplasmic male sterility in Burley tobacco. Four cytoplasmic male sterile lines and their male-fertile counterparts and 21 Fi hybrids and their parents were evaluated for their agronomic performance in replicated field trials. Some F1 hybrids were comparable to Burley 21, the only Burley cultivar in Korea. Among 21 F1 hybrids, MS L8$\times$Burley 49 and three other hybrids showed 2-11% and 1-5% higher yield and price per kg than Burley 21, respectively.

  • PDF

DIGITAL INFRARED THERMAL IMAGING IN OSTEOPOROSIS

  • Lee, Kyung-Sub;Kim, Yong-Suk
    • Journal of Oriental Medical Thermology
    • /
    • v.1 no.1
    • /
    • pp.1-6
    • /
    • 2002
  • This study examined the relationship between bone mineral density and DITI in the diagnosis of osteoporosis. An analysis was performed on the thermographic findings of 20 patients without osteoporosis, 20 with osteopenia and 20 with osteoporosis at the Kangnam Korean Hospital, KyungHee University, Seoul, Korea, from June 1998 to February 1999. The osteoporosis was measured by LUNAR PIXI and the body temperature was assessed by DITI. Thermogrphic measurements were performed on 4 areas(acupuncture point: CV12, CV4, BL23 and BL26). All data were coded for computer analysis and significances were tested by Duncan test. There was no significant difference in age among the three groups of patients. DITI revealed the significant hypothermia (p<0.001) on the osteoporosis patients compared with osteopenia and normal bone density patients. It is believed that DITI may be a favorable alternative to the diagnosis of osteoporosis.

  • PDF

Effect of Amino Acids on Callus Induction from Bentgrass (아미노산이 Bentgrass 캘러스 유도에 미치는 영향)

  • Ming Liang Chai
    • Asian Journal of Turfgrass Science
    • /
    • v.12 no.4
    • /
    • pp.189-194
    • /
    • 1998
  • The effect of proline, glutamine, aspartic acid and their combinations on callus induction and embriogenic callus formation from 3 creeping bentgrass (Agrostis palustris) cv. Regent, Mariner, Cato and 1 colonial bentgrass (Agrostis tenuis) cv. Tiger was estimated in both light and dark condition. The addition of amino acids to the growth medium did not have a significant stimulatory effect on the induction of embryogenic callus, instead, they were inhibitory, particularly at higher concentration (40 mM). But supplement of amino acids at lower concentrations (5 or 10mM) to basal medium was beneficial in inhibiting the formation of hairy outgrowth on the surface of embryogenic callus.

  • PDF

High Efficiency of Plant Regeneration from Seed-Derived Callus of Zoysiagrass cv. Zenith (Zoysiagrass japonica의 효율적인 재분화체계에 관한 연구)

  • Ming Liang Chai
    • Asian Journal of Turfgrass Science
    • /
    • v.12 no.4
    • /
    • pp.195-202
    • /
    • 1998
  • The development of a protocol for high efficiency of embryogenic callus separation, maintenance and plant regeneration from the seeds of zoysiagrass cv. Zenith was studied. Embryogenic callus ratio is absolutely determined by genotype, but by adding high concentration of copper into medium, changing light condition and maintaining callus on initial induction medium for 8∼10 weeks, embryogenic callus can be easily distinguished and its growth can be promoted. There were significant differences among selected callus lines (each from one seed) according to their growth rates and regeneration percentages. Callus pre-treatment with activated charcoal inhibited callus growth, increased the level of precocious germination during culture and promoted shoot cluster formation after transfer to regeneration medium. For long-term callus maintenance, N6AA medium was better than MS medium, because the former inhibited non-embryogenic callus formation and kept vigor of embryogenic callus. The best callus lines Z-(5) has been successfully used for transformation and somaclonal variation selection in our laboratory.

  • PDF

Effect of Acupuncture and Moxibustion Treatment in a Patient with Parkinson's Disease - A Case Study (침구치료로 호전된 파킨슨 환자 치험 1례)

  • Han, In-sik;Sun, Seung-ho
    • The Journal of Internal Korean Medicine
    • /
    • v.39 no.2
    • /
    • pp.286-291
    • /
    • 2018
  • Objective: This clinical study aims to report the effect of acupuncture and moxibustion treatment in a patient with Parkinson's disease. Methods: The patient was treated with acupuncture totally eight times, which was applied at LU8, LR4, HT3, LR2, GV20, and GB20 and moxibustion at CV12, CV4. The effect of treatment was evaluated using the Unified Parkinson's Disease Rating Scale (UPDRS). Results: After treatment the patient's UPDRS scores improved from 78 to 29 points after 28 days, and the patient's symptoms of tremor also improved. Conclusions: The Korean medicine treatment of acupuncture might be effective for Parkinson's disease.

Degree of Heterosis in Diallel Crosses of Burley and Chinese Sun-cured Tobacco (Nicotiana tabacum L.) (버어리종 연초와 중국 양건종의 이면교잡에 의한 양적형질의 잡종강세정도)

  • 이호림;조천준;류점호
    • Journal of the Korean Society of Tobacco Science
    • /
    • v.23 no.2
    • /
    • pp.95-102
    • /
    • 2001
  • This study was conducted to obtain the basic information for breeding of burley(N. tabacum cv. burley) and sun-cured tobacco(N. tabacum cv. sun-cured) variety. Two burley(Burley 21, KB 108), and T.I. 1068 and three sun-cured varieties(Yeonbyeon 3, Jaheungyeon and Jaraehong) were diallel crossed and 15 combinations of F$_1$generations were made in 1998, respectively. Six parental varieties, 15 F$_1$s were grown under the complete randomized block design with 3 replications at Chonju Experiment Station, Korea Ginseng & Tobacco Research Institute in 2000. The data of 12 quantitative characters were measured for degree of heterosis. The results obtained are as follows. Heterosis of F$_1$generation was positive in weight per leaf, plant height, stem diameter, yield, leaf length and total alkaloid content. Cross combinations between either Burley 21 or KB 108 and sun-cured varieties showed comparatively high heterosis in each characters.

  • PDF