• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3569-3573
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• 2016

Purpose: The aim of this study was to compare C-11 choline and F-18 FDG PET/CT, gadoxetic-enhanced 3-T MRI and contrast-enhanced CT for diagnosis of hepatocellular carcinoma (HCC). Materials and Methods: Twelve chronic hepatitis B patients suspected of having HCC by abdominal ultrasonography received all diagnostic modalities performed within a one-week timeslot. PET/CT results were analyzed visually by two independent nuclear medicine physicians and quantitatively by tumor to background ratio (T/B). Nine patients then had histopathological confirmation. Results: Six patients had well differentiated HCC, while two and one patient(s) were noted with moderately and poorly differentiated HCC, respectively. All were detected by both CT and MRI with an average tumor size of $5.7{\pm}3.8cm$. Five patients had positive C-11 choline and F-18 FDG uptake. Of the remaining four patients, three with well differentiated HCC showed negative F-FDG uptake (one of which showed negative results by both tracers) and one patient with moderately differentiated HCC demonstrated no C-11 choline uptake despite intense F-18 FDG avidity. The overall HCC detection rates with C-11 choline and F-18 FDG were 78% and 67%, respectively, while the sensitivity of F-18 FDG for non-well differentiated HCC was 100%, compared with 83% of C-11 choline. The average T/B of C-11 choline in well-differentiated HCC patients was higher than in moderately and poorly differentiated cases (p=0.5) and vice versa with statistical significance for T/B of F-18 FDG (p = 0.02). Conclusions: Our results suggested better detection rate in C-11 choline for well differentiated HCC than F-18 FDG PET. However, the overall detection rate of PET/CT with both tracers could not compare with contrast-enhanced CT and MRI.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2002년도 추계학술대회 논문집
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• pp.335-340
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• 2002

In recent years, the study of metal matrix composite has increased specially, aluminum alloy, research and development are briskly progress to find new metal matrix composite. this study is following the this purpose; This study is used metal matrix composite that was produced by matrix, AC4CH. and reinforcement $A_{18}B_4O_{33}$ metal matrix composite to add $Al_2O_3,\;TiO_2$ for strengthen of binding together among the Whisker. Each Metal matrix composite is produced using the squeeze casting method. Fracture tounghness test was in accordance with the provisions of ASTM E399; Specimen was produced half-size CT specimen W=25mm, B=12.5mm, Cross head speed 0.05mm/min in room temperature. The plane strain fracture toughness $K_{IC}$ is $8.7MPa-m^{0.5}$ for $Al_{18}B_4O_{33}$/AC4CH., $9.28MPa-m^{0.5}$ for $Al_{18}B_4O_{33}$/AC4CH added $TiO_2$. and $Al_2O_3$ but AC4CH alloy was violated the critical stipulated by ASTM standard for a valid measurement of $K_{IC}$. In case of, it was performed $I_{IC}$ test instead of $K_{IC}$ based on ASTM E 1820

• Nuclear Medicine and Molecular Imaging
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• 제42권4호
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• pp.333-336
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• 2008

A 52-year-old woman with a history of general weakness, fatigue, weight loss, elevated serum levels of liver transaminase enzyme for three months underwent an F-18 FDG PET/CT scan to evaluate a cause of the hepatosplenomegaly found on abdominal ultrasonography. Initial PET/CT revealed markedly enlarged liver and spleen with intense FDG uptake. Otherwise, there were no areas of abnormal FDG uptake in whole body image. Histological evaluation by a hepatic needle biopsy demonstrated diffuse large B cell type lymphoma and final diagnosis for this patient was hepatosplenic B-cell lymphoma. She received five cycles of CHOP chemotherapy, and second PET/CT scan was followed after then. Follow-up PET-CT revealed normal sized liver with disappearance of abnormal FDG uptake. Hepatosplenic B-cell lymphoma is relatively rare and mostly presents as single or multiple nodules.1,2 Diffuse type hepatosplenic lymphoma is extremely rare and poorly recognized entity.3 The diagnosis is very difficult and complicated by the presence of misleading symptoms.4 In this rare hepatosplenic B-cell lymphoma case, F-18 FDG PET/CT scan provided a initial diagnostic clue of hepatosplenic lymphoma and an accurate chemotherapy response.

• 한국정보통신학회논문지
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• 제17권10호
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• pp.2273-2280
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• 2013

본 논문에서는 차세대 항공 감시시스템에 대하여 소개하고, 지상국 수신기 전단부 저잡음 증폭기 설계에 관하여 연구하였다. 국제 표준 문서와 기존 제품의 성능을 고려하여 수신감도, 신뢰성 등이 경쟁력 있게 전체 시스템을 링크 버짓 하였으며, 이에 적합한 저잡음 증폭기를 얻기 위해 이득, 이득 평탄도, 반사손실 등을 최적이 되도록 설계 규격을 결정하였다. 설계시 저전력, 저잡음, 고이득 특성에 적합한 바이어스 회로를 구성하였으며, 최적 설계 후 실시한 모의실험 결과로 이득은 16.24dB, 잡음지수는 0.36dB, 입출력 반사손실은 각각 -18dB와 -28dB, 주파수 안정도는 1.11을 얻었고, 제작 후 측정 결과는 이득 17dB, 잡음지수 0.51dB, 이득 평탄도 0.23dB, 입출력 반사손실은 각각 -18.28dB, -24.50dB로 전체 시스템 구성에 적합한 결과를 얻었다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2008년도 하계종합학술대회
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• pp.539-540
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• 2008

This paper presents an ultra-wideband (UWB) CMOS low noise amplifier (LNA) topology that operates in 3.1-10.6GHz band. The common gate structure provides wideband input matching and flattens the passband gain. The proposed UWB amplifier is implemented in 0.18 um CMOS technology for lower band operation mode. Simulation shows a minimum NF of 2.35 dB, a power gain of $18.3{\sim}20\;dB$, better than -10 dB of input and output matching, while consuming 16.4 mW.

• 한국미생물·생명공학회지
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• 제37권1호
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• pp.1-9
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• 2009

식물성장촉진물질인 auxin을 비롯한 식물병원성진균을 방제하는 siderophore 그리고 식물병원성 진균의 세포벽을 분해하는 cellulase를 동시에 생산하는 생물방제균주 B. subtilis AH18의 토양내 monitoring을 위하여 각 생산물질에 관여하는 유전자를 기초로 primer(sid, aec, cel)를 제작하였다. Single PCR 및 multiplex PCR을 수행하여 800-bp(sid), 1000-bp(air), 1600-bp(cel)의 DNA fragment를 확인하였으며, 각각의 fragment는 siderophore의 생합성 key enzyme인 2,3-dihydro-2,3-dihydroxy benzoate dehydrogenase[EC : 1. 3. 1, 28]gene (sid-794bp)이며, auxin efflux carrier gene (aec - 1052 bp), 그리고 cellulase gene(cel - 1582 bp)임을 확인하고, NCBI Genbank에 등록하였다(Genbank accession sid: No. EF408238, aec: No. EF408239, cel: No. EF070194). 또한 B. subtilis AH18을 처리한 일반 경작지 토양에서 multiplex PCR을 통하여 3종의 유전자에서 증폭된 triple band를 확인하였으며, 고추를 실제 토양을 이용해 Pot에 이식 후 고추의 rhizosphere와 non-rhizosphere에서 B. subtilis AH18의 존재를 확인할 수 있다. 뿐만아니라 본 균주를 고추가 이식된 Pot의 토양에 처리 후 monitoring시 민감도는 $1.8\times10^5$ cfu/g이었고, monitoring 가능한 기간은 3주이상 확인 할 수 있었다.

• 한국동물학회지
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• 제31권2호
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• pp.142-146
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• 1988

PAH화합물의 하나인 benzo(a)pyrene의 쥐 태반 microsomes에 의한 대사활성화를 조사하였다. B(a)P대사물은 C18- $\mu$ Bondapak칼럼을 사용하여 고압액체크로마토그래피로 분석하였다. 그 결과 B(a)P를 투여한 쥐의 태반 microsomes에 의한 주 대사산물은 발암성이 강한 7,8-diol B(a)P였으며, 또한 적은량의 4,5-diol B(a)P와 quinone류가 검출되었다. 3-methyl-cholanthrene을 투여한 경우 hydroxy B(a)P 와 quinone화합물이 주 대사산물이었으며 Phenobarbital을 전처리했을 경우 7,8-diol B(a)P이 주 대사산물인 것으로 나타났다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.785-790
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• 2013

Background: Persistent infection of one or more of about 15 high-risk human papillomaviruses (HR-HPVs), most commonly HPV types 16/18, has a significant role in cervical cancer initiation and progression. There are limited data available from north-east India about HPV prevalence though this region has high incidence rates of cervical cancer. The aim of this study was to investigate the HPV genotypes prevalent in cervical cancer patients of north-east India. Materials and Methods: We analyzed 107 cervical cancer patient samples. Nested multiplex PCR assays were employed for detection of 13 high risk and 5 low risk HPV types. Results: HPV was confirmed in 105 samples. The presence of 6 'carcinogenic' HPV types, HPV-16 (88%), -18 (15%), -31(4%),-45 (3%), -59 (4%), -58(1%), and one non carcinogenic, HPV-6/11 (6%), was recorded. Among various demographic and clinical factors only tumour stage showed a statistically significant association with HPV type infection (P=0.019). Conclusions: We suggest that the most prevalent genotype is HPV-16 followed by HPV-18 in cervical carcinoma patients of the north-eastern region of India. Advanced tumour stage may be associated with increased possibility of harbouring multiple HPV genotypes.

• Journal of Species Research
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• 제7권2호
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• pp.135-150
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• 2018

Eleven bacterial strains 17SD2_15, 17Sr1_23, 17SD2_13, 17Sr1_31, 17gy_18, 16B15D, 16B02D, 16B04G, 16B01D, 17U4-2 and 17J28-10 assigned to the phylum Proteobacteria were isolated from soil samples collected from Seoul Women's University, in South Korea. The Belnapia species, strain 17SD2_15 was cocci-shaped and pink-colored. The Methylobacterium species, strain 17Sr1_23, 17SD2_13, 17Sr1_31, and 16B15D were short rod-shaped and pink-colored. The Microvirga species, strain 17gy_18, and 16B02D were short rod-shaped and pink-colored. The Oxalicibacterium species, strain 16B04G was short rod-shaped and pink-colored. The Sphingomonas species, strain 16B01D was short rod-shaped and yellow-colored. The Variovorax species, strain 17U4-2 was cocci-shaped and yellow-colored. The Paracoccus species, 17J28-10 was cocci-shaped and orange-colored. Phylogenetic analysis based on 16S rRNA gene sequence showed that strains 17SD2_15, 17Sr1_23, 17SD2_13, 17Sr1_31, 17gy_18, 16B15D, 16B02D, 16B04G, 16B01D, 17U4-2 and 17J28-10 were most closely related to Belnapia soli (with 99.9% similarity), Methylobacterium gregans (99.1%), Methylobacterium isbiliense (99.6%), Methylobacterium oxalidis (99.9%), Microvirga aerilata (98.7%), Methylobacterium aerolatum (99.0%), Microvirga vignae (100.0%), Noviherbaspirillum canariense (100.0%), Sphingomonas desiccabilis (100.0%), Variovorax humicola (99.6%), and Paracoccus acridae (99.1%), respectively. This is the first report of these eleven species in Korea.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1998년도 추계종합학술대회 논문집
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• pp.675-678
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• 1998

In this paper, power amplifiers for PCS phone were designed with the GEC Marconi H40 HEMT libray. The 1st stage was carefully designed in order to obtain k〉1 using a parallel resistor, and its S21 gain of 18.3dB and input reflection coefficient of -4dB were obtained. And S21 gain of 18dB and input reflection coefficient of -7dB were obtained from the 2nd stage. Finally, total S21 gain of 38dB, input reflection coefficient of -16dB, power gain of 35.2dB, output power of 28.7dBm and PAE(power added efficiency) of 29% were obtained from the designed MMIC power amplifiers. The chip size is $1.729$\times$0.94\textrm{mm}^2.$