• Bulletin of the Korean Chemical Society
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• v.24 no.5
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• pp.579-582
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• 2003

Norfloxacin, that inhibits the action of topoisomerase Ⅱ, binds to wide variety of DNA. The binding mode of this drug to double- and super-coiled DNA (ds- and scDNA) is compared in this study by various spectroscopic methods, including absorption, fluorescence, and circular dichroism(CD) spectroscopy. Hypochromism in the absorption band, negative and positive induced CD bands (respectively in 240-260 nm and 270-300 nm region) are apparent for the norfloxacin that bound to both the dsDNA and scDNA. A decrease in fluorescence is also noticed in the presence of both DNAs. Since the spectroscopic characteristics are the same for both complexes, it is imperative that the binding mode of the norfloxacin is similar in ds- and scDNA. In the presence of $Mg^{2+}$, which is a cofactor in the topoisomerase Ⅱ action, the fluorescence intensity of the scDNA-norfloxacin complex increased and the resulting fluorescence intensity and shape was identical to that in the absence of scDNA. Therefore, the addition of an excess amount of $Mg^{2+}$ may result in the extrusion of norfloxacin from scDNA.

• Geomechanics and Engineering
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• v.18 no.5
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• pp.481-492
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• 2019

Due to the underground openings, the tangentially concentrated stress of the tunnel remains larger at excavation boundary and decreases toward the interior of the surrounding rock with a certain gradient. In order to study the effect of different gradient stress on rockburst, the true-triaxial gradient and hydraulic-pneumatic combined test apparatus were carried out to simulate the rockburst processes. Under the different gradient stress conditions, the rock-like specimen (gypsum) was tested independently through three principal stress directions loading--fast unloading of single surface--top gradient and hydraulic-pneumatic combined loading, which systematically analyzed the macro-mesoscopic damage phenomena, force characteristics and acoustic emission (AE) signals of the specimen during rockburst. The experimental results indicated that the rockburst test under the gradient and hydraulic-pneumatic combined loading conditions could perfectly reflect the rockburst processes and their stress characteristics; Relatively high stress loading could cause specimen failure, but could not determine its mode. The rockburst under the action of gradient stress suggested that the failure mode of specimen mainly depended on the stress gradient. When the stress gradient was lower, progressive and static spalling failure occured and the rockburst grades were relatively slight. On the other hand, shear fractures occurred in rockbursts accounted for increasingly large proportion as the stress gradient increased and the rockburst occurred more intensely and suddenly, the progressive failure process became unconspicuous, and the rockburst grades were moderate or even stronger.

• Geomechanics and Engineering
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• v.24 no.2
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• pp.157-166
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• 2021

This paper aims at the temperature and slenderness ratio effects on physical and mechanical properties of Beishan granite. A series of uniaxial compression tests with various slenderness ratios and temperatures were carried out, and the acoustic emission signal was also collected. As the temperature increases, the fracture aperture of intercrystalline cracks gradually increases, and obvious transcrystalline cracks occurs when T > 600℃. The failure patterns change from tensile failure mode to ductile failure mode with the increasing temperature. The elastic modulus decreases with the temperature and increases with slenderness ratio, then tends to be a constant value when T = 1000℃. However, the peak strain has the opposite evolution as the elastic modulus under the effects of temperature and slenderness ratio. The uniaxial compression strength (UCS) changes a little for the low-temperature specimens of T < 400℃, but a significant decrease happens when T = 400℃ and 800℃ due to phase transitions of mineral. The evolution denotes that the critical brittle-ductile transition temperature increases with slenderness ratio, and the critical slenderness ratio corresponding to the characteristic mechanical behavior tends to be smaller with the increasing temperature. Additionally, the AE quantity also increases with temperature in an exponential function.

• Composites Research
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• v.16 no.5
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• pp.45-53
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• 2003

The experimental and numerical investigations on the failure characteristics of the secondary bonded composite single-lap joints were performed. The initiations and growths of cracks were observed using CCD camera and acoustic emission sensor during the tension tests of the joint specimens. The structural behaviors of the specimens were predicted by the geometric nonlinear two-dimensional finite element analysis. The three types of observed initial cracks were included in each finite element models and the strain energy release rates of each specimen models were calculated by VCCT(Virtual Crack Closure Technique) technique. The tension tests showed that the initial cracks occurred in the 60∼90% of final failure loads and the major failure modes of the specimens were adhesive failure and the delamination between the 1st and 2nd ply of laminate. The specimens with the thicker bondline had earlier crack initiation loads but higher crack propagation resistance and eventually better loading capability. The delaminations were mostly observed in the thicker bondline specimens. The mode I values of calculated strain energy release rates were higher than the mode II values in the all specimen models considering the three types of initial cracks. The mode I and total strain energy release rates were calculated as higher values in the order of initial crack in the edge interface, comer interface and delamination between the plies of laminate.

• Korean Journal of Optics and Photonics
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• v.15 no.5
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• pp.415-422
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• 2004

We propose and present a new multiplexed bend loss type single-mode fiber-optic sensor system for displacement measurement in order to measure the displacement of several mm of civil engineering structures such as bridges and buildings. We make a bend loss type fiber-optic sensor for measuring displacements using the signal difference between two reflection signals due to various bend losses generating at a pair of optical connectors by using the optical time domain reflectometer. And we fabricate a multiplexed bend loss type fiber-optic sensor detecting linear displacements of 4 measuring positions of an object by setting these new 4 fiber-optic sensors on a single mode fiber simultaneously. We find that the multiplexed fiber-optics displacement sensor has linearity of 0.9942, maximum displacement of 6 mm, and accuracy of 6% for 4 measuring points.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.30 no.3
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• pp.100-108
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• 2019

Objectives: Adolescence involves a number of developmental processes, as well as unique psychological characteristics and behaviors. An increased rate of internet and game addictions, school violence, and suicide may either represent aspects of adolescence or a psychopathological phenomenon. There is an urgent need to develop software programs that can prevent and resolve adolescent behavioral problems. We applied the mentalization theory to interpret and find solutions for problems faced by adolescent characters in literature. Methods: In Joan Rowling's novel "Casual Vacancy," Sukhvinder is a girl with problems representative of those encountered by modern adolescents; she is a victim of bullying and engages in self-mutilation. We targeted her problematic behaviors as representative of a prementalized state. Results: Born into an upper-class English family with Pakistani origins, Sukhvinder, unlike her siblings, fails her parents' expectations. Whenever she faces a psychological crisis, she regresses into the teleological mode (the most primitive pre-mentalization stage) and regains her sense of self by cutting herself. After her friend's suicide, however, she begins to communicate with her parents and moves toward mentalization. Conclusion: By analyzing Sukhvinder's behavior, we assessed patterns of attachment, empathy, and mentalization, and identified corrective approaches for problematic behaviors. We believe that the presented interpretation may serve as a foundation for the development of models for understanding adolescent deviant behaviors.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.1
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• pp.184-192
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• 2022

Valve internal leakage is caused by damage to the internal parts of the valve, resulting in accidents and shutdowns of the piping system. This study investigated the possibility of a real-time leak detection method using the acoustic emission (AE) signal generated from the piping system during the internal leakage of a butterfly valve. Datasets of raw time-domain AE signals were collected and postprocessed for each operation mode of the valve in a systematic manner to develop a data-driven model for the detection and classification of internal leakage, by applying machine learning algorithms. The aim of this study was to determine whether it is possible to treat leak detection as a classification problem by applying two classification algorithms: support vector machine (SVM) and convolutional neural network (CNN). The results showed different performances for the algorithms and datasets used. The SVM-based binary classification models, based on feature extraction of data, achieved an overall accuracy of 83% to 90%, while in the case of a multiple classification model, the accuracy was reduced to 66%. By contrast, the CNN-based classification model achieved an accuracy of 99.85%, which is superior to those of any other models based on the SVM algorithm. The results revealed that the SVM classification model requires effective feature extraction of the AE signals to improve the accuracy of multi-class classification. Moreover, the CNN-based classification can be a promising approach to detect both leakage and valve opening as long as the performance of the processor does not degrade.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2008.05a
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• pp.225-228
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• 2008

In this paper, we presented our implementation of a counter mode AES based on Virtex4 FPGA. Our design exploits three advanced features: composite field arithmetic SubByte, efficient MixColumn transformation, and On-the-Fly Key-Scheduling for fully pipelined architecture. By pipelining the composite field implementation of the S-box, the area cost is reduced to average 17 percent. By designing the On-the-Fly key scheduling, we implemented an efficient key-expander module which is specialized for a pipelined architecture.

• Proceedings of the KIEE Conference
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• 2004.07c
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• pp.2046-2048
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• 2004

In this paper, we have proposed a novel omnidirectional power divider/combiner configuration. By using the even- and odd- mode analysis. we analyse the proposed power divider/combiner circuit. In order to show the validity of the presented power divider/combiner circuit. We have designed and implemented the proposed circuit of the center frequency of 2.3GHz.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.94.1-94.1
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• 2013

Whistler mode chorus waves, which are observed outside the plasmasphere of the Earth's magnetosphere, play a major role in accelerating and scattering energetic electrons in the radiation belts. In this study we developed a predicting scheme of the global distribution of chorus by using the Time History of Events and Macroscale Interactions during Substorms (THEMIS) satellite data. First, we determined global spatial distributions of chorus activity, and identified fit functions that best represent chorus intensities in specific L-MLT zones. Second, we determined the specific dependence of average chorus intensity on preceding solar wind conditions (e.g., solar wind speed, IMF Bz, energy coupling degree) as well as preceding geomagnetic states (as represented by AE, for example). Finally, we combined these two results to develop the predicting functions for the global distribution and intensity of chorus. Implementing these results in the radiation belt models should improve the local acceleration effect by chorus waves.