• 제목/요약/키워드: $A{\beta}42$

검색결과 805건 처리시간 0.029초

A comparison of single-epoch black hole masses at z>0.5

  • Karouzos, M.;Woo, Jong-Hak;Matsuoka, Kenta;Onken, Christopher;Kollmeier, Juna;Park, Dawoo;Nagao, Tohru
    • 천문학회보
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    • 제40권1호
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    • pp.42.1-42.1
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    • 2015
  • Accurately estimating black hole (BH) masses at high redshifts is imperative in the current and future era of large-area extragalactic spectroscopic surveys. We present an extension of existing comparisons between rest-frame UV and optical virial BH mass estimators to intermediate redshifts, lower luminosities, and lower BH masses, comparable to the local $H{\beta}$ reverberation-mapping sample. We use data from the AGES survey and also newly acquired near-infrared spectra from the FMOS instrument on Subaru telescope for 89 broad-lined active galaxies at redshifts between 0.5 and 1.6. We focus on the MgII, CIV, and CIII broad emission lines and compare them to both $H{\alpha}$ and $H{\beta}$, using two different prescriptions to describe their emission profile width. We confirm that MgII shows a tight correlation with $H{\alpha}$, with a scatter of ~0.25 dex. The CIV and CIII estimators can be considered viable virial mass estimators, despite large scatter values. We combine our dataset with previous high redshift and high luminosity CIV and CIII measurements from the literature and we calculate a scatter of $\sim0.4$ dex and an offset to the 1:1 relation consistent with 0 for the combined sample. This updated comparison spans a total of 4 decades in BH mass, a much wider range than any previous individual study.

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방사선사 조직의 조직유효성에 영향을 미치는 변수에 관한 연구 (A Study on the Variables Affecting on the Organizational Effectiveness of Radiological Technologist)

  • 김선화;김정훈;박은태
    • 대한방사선기술학회지:방사선기술과학
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    • 제42권3호
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    • pp.231-238
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    • 2019
  • Medical institutions are abundant in human resources and have a unique structure with diverse professions and various organizational cultures coexist. This organizational culture influences organizational effectiveness and influences the effectiveness of the organization as a factor of leadership and organizational culture. Leadership is an important factor in linking employee behavior to organizational commitment to achieve job satisfaction. The purpose of this study was to analyze the effect of organizational effectiveness on organizational culture, leadership perception, and job stress in a special organization called radiologist. As a result, organizational culture and transformational leadership showed high correlation with 0.627. Among the organizational effectiveness variables, organizational commitment showed the highest influence with transformational leadership(${\beta}=0.284$, p<0.001), and job satisfaction was also the highest with transformational leadership (${\beta}=0.440$, p<0.001). The results showed that the expectation of transformational leadership affects organizational commitment and job satisfaction. In order to expect a positive change in the effectiveness of the organization, the radiologist culture requires an organizational culture that can fully demonstrate autonomy and creativity, and transformational leadership is required for this.

기업 사이버교육 학습자들의 내적통제소재, 상호작용, 만족도, 학습지속의향 간의 구조적관계 (The Structural Relationship among Internal Locus of Control, Interaction, Satisfaction and Learning Persistence in Corporate e-Learning)

  • 주영주;심우진;김은경;박수영
    • 지식경영연구
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    • 제10권4호
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    • pp.31-42
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    • 2009
  • With the rapid development of information technology, e-learning is growing in corporate. However, there are still problems in learning, such as low learning persistence rate. Learning outcomes are complex phenomenon influenced by a multitude of factors, it is need to considering the direct and indirect causal relationship among various factors. Therefore, the purpose of this study was to develop the causal model that explains the learning outcomes (satisfaction learning persistence) in corporate e-learning. This study was also intended to examine the causal relationship between the interaction and learning persistence through satisfaction mediators. For this, online survey was conducted with a sample of 270 learners who enrolled in cyber training course at A company. The major findings of this study are as follows: First, internality (internal locus of control, ${\beta}=.154$), interaction (${\beta}=.489$), satisfaction (${\beta}=.304$) have direct effect on learning persistence. Second, the interaction has direct effect on the satisfaction (${\beta}=.320$). Third, the satisfaction has direct effect on the learning persistence, and mediating the interaction and learning persistence. This result will contribute to build a learning strategy to improve learning outcomes.

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간호대학생의 성격강점이 지각된 스트레스에 미치는 영향 (The Influence of Nursing Students' Character Strength on Perceived Stress)

  • 유미옥
    • 한국산학기술학회논문지
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    • 제18권2호
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    • pp.168-176
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    • 2017
  • 본 연구는 간호대학생의 성격강점이 지각된 스트레스에 미치는 영향을 파악하기 위한 서술적 조사연구이다. 자료 수집은 A지역의 간호학과 학생 174명을 대상으로 하였으며, 수집된 자료는 SPSS WIN 21.0 프로그램을 이용하여 분석하였다. 본 연구의 결과 대상자의 성격강점은 $3.46{\pm}.34$점(5점 척도) 이었고, 지각된 스트레스는 $2.84{\pm}.42$점(5점 척도)이었으며, 성격강점 중 가장 점수가 높은 하위영역은 인간애로 $3.65{\pm}.49$점이었다. 간호대학생의 지각된 스트레스는 성격강점과 부적 상관 관계(r=-.50, p<.001)를 보이는 것으로 나타났고, 지각된 스트레스는 성격강점의 하위영역 모두에 부적 상관관계를 보였다. 또한 간호 대학생의 지각된 스트레스에 영향을 미치는 요인은 일반적 특성의 매우 어려운 가정형편(${\beta}=.146$, p=.026)과 성격 강점의 하위요인 중 용기(${\beta}=-.250$, p=.006)와 초월성(${\beta}=-.275$, p=.013)으로 나타났으며, 세 요인은 지각된 스트레스를 39.5% 설명하는 것으로 나타났다. 따라서 간호학과의 교수진이나 상담 직원들은 이와 같은 결과를 통해 간호학과 학업을 힘들어 하는 학생들에게 성격강점을 확인시켜주고 스트레스를 경감시킬 수 있는 중재 방안을 모색해야 할 것이다.

지황 (地黃)의 성분연구 (Phytochemical Studies on Rehmanniae Radix)

  • 이소영;연민혜;김주선;이제현;강삼식
    • 생약학회지
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    • 제42권2호
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    • pp.127-137
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    • 2011
  • Twenty-four compounds were isolated from the 70% ethanolic extract of Rehmanniae Radix (Scrophulariaceae) cultivated in Ubo-myeon, Gunwi-gun, Gyeongbuk province, Korea and their structures were identified as four iridoids [6-O-(4''-O-${\alpha}$-L-rhamnopyranosyl) vanilloyl ajugol (17), ajugol (18), aucubin (19), and catalpol (20)], three phenethyl alcohol glycosides [decaffeoyl acteoside (15), isoacteoside (16), and acteoside (21)], five sugar derivatives [ethyl ${\beta}$-D-fructofuranoside (7), eleutheroside C (14), mannitol (22), raffinose (23), and stachyose (24)], two terpenoids [remophilanetriol (4) and glutinolic acid (11)], a lignan, paulownin (2), and eight others [${\beta}$-sitosterol (1), daucosterol (6), monopalmitin (3), pinellic acid (9), uracil (5), adenosine (12), jio-cerebroside (10), aeginetic acid 5-O-${\beta}$-D-quinovoside (8), aeginetoyl ajugol 5''-O-${\beta}$-D-quinovoside (13)]. The chemical structures of these compounds were identified on the basis of spectroscopic methods and comparison with literature values. Among these compounds, paulownin (2), monopalmitin (3), uracil (5), daucosterol (6), ethyl ${\beta}$-D-fructo-furanoside (7), and eleutheroside C (14) were isolated from this plant for the first time.

여자간호사가 인식하는 남자간호사에 대한 이미지 영향요인 (Factors Affecting Female Nurse's Image of Male Nurses)

  • 이은수;권혁수;이양숙
    • 가정∙방문간호학회지
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    • 제24권3호
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    • pp.336-344
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    • 2017
  • Purpose: The purpose of this study was to examine job recognition of female nurses and perceived image of male nurses, and to investigate predictive factors affecting this perceived image. Methods: A survey was conducted between September and October 2015 with 143 female clinical nurses who worked at hospitals. Data were analyzed using the SPSS 21.0 correlation and multiple regression analyses. Results: The findings of this study were as follows : Female nurses recognition had positive correlations with images of male nurses. Social image(r=.41, p<.001), professional image(r=.45, p<.001), and nursing job prospects(r=.49, p<.001) were significantly correlated with perceived image of male nurses. Nursing job prospect(${\beta}=.193$, p=.049), perception that male nurses were suitable for their jobs(${\beta}=.329$, p<.001), mass media experience related to male nurses(${\beta}=.244$, p<.001), social image(${\beta}=.225$, p=.009) and professional image(${\beta}=.191$, p=.021) explained 42.7% of the variance in image of male nurses. Conclusions: The findings of this study suggest that nursing education and research should find concrete ways to improve perceived image of male nurses. It will enhance the quality of nursing service by improving male nurses' communication and collaboration with female nurses.

비다문화 중학생과 다문화 중학생의 우울 관련 요인 비교 (Comparison of Factors influencing Depression between Non-Multicultural and Multicultural Middle School Students)

  • 장형순;박현주
    • 한국학교보건학회지
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    • 제32권1호
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    • pp.10-19
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    • 2019
  • Purpose: The purpose of this study was to compare the factors related to depression between non-multicultural and multicultural middle school students. Methods: In this study, data were collected using structured questionnaires targeting students of 9 middle schools in G Province, Korea. Finally, the data of 304 students were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation, and multiple regression analyses using SPSS 24.0. Results: The multicultural students showed a higher depression score ($47.14{\pm}8.33$) than the counterpart ($44.22{\pm}8.11$) (p<.001). The results of the multiple regression analysis revealed that academic stress (${\beta}=.33$, p<.001), peer attachment (${\beta}=-.13$, p<.02), and body image (${\beta}=.25$, p<.001) were the influencing factors on depression in non-multicultural students. However, in multicultural students, depression was related to peer attachment (${\beta}=-.16$, p=.03) and self-esteem (${\beta}=-.42$, p<.001). Conclusion: To prevent and manage depression in non-multicultural middle school students, it is essential to help them relieve academic stress and build peer relationships and positive body image. For multicultural middle school students, helping them to have high self-esteem and peer attachment would be the first measure to prevent and manage depression.

임상간호사의 완벽주의 성향과 대처유형이 소진에 미치는 영향 (Influence of Perfectionism and Coping Styles on Burnout in Clinical Nurses)

  • 유지혜;최현경
    • 한국직업건강간호학회지
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    • 제28권1호
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    • pp.64-74
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    • 2019
  • Purpose: The purpose of this study was to identify the influencing factors on burnout after analyzing the relationship among clinical nurses' various perfectionism and coping styles. Methods: A descriptive, cross-sectional study was conducted with 200 clinical nurses who had six months or more years of clinical experiences from two general hospitals located in D city. The data were analyzed by t-test, one-way ANOVA, Pearson's correlation coefficients, and stepwise regression analysis using IBM SPSS statistics 23.0 program. Results: The burnout of clinical nurses was positively correlated with socially prescribed perfectionism and negatively correlated with active coping style. Socially prescribed perfectionism was positively correlated with active coping style and passive coping style. Influencing factors on the burnout of clinical nurses were socially prescribed perfectionism (${\beta}=.37$), satisfied work unit (${\beta}=-.64$) and neutral satisfaction of work unit (${\beta}=-.27$), over 40 years of age (${\beta}=-.21$), and active coping style (${\beta}=-.14$). The model consisting of these variables explained 42% of variance of burnout in clinical nurses. Conclusion: Based on the findings of this study developing intervention programs that consider influencing factors such as perfectionism and coping styles is needed to reduce the level of burnout of clinical nurses.

중년기 성인의 혈중 항산화 물질 분석 및 혈중 지질과 신체계측치와의 상관성 (Analysis of Serum Antioxidant Materials Concentration and Their Relation with Blood Lipids and Anthropometric Indices in Middle-Aged Adults in Korea)

  • 이현정;이덕희;김광옥;김유정;이혜성
    • Journal of Nutrition and Health
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    • 제42권5호
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    • pp.464-473
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    • 2009
  • 본 연구에서는 우리나라 건강한 중년성인의 혈청 carotenoids류 (${\alpha}$-carotene, ${\beta}$-carotene, ${\beta}$-cryptoxanthin, lutein, lycopene)와 ${\alpha}$-tocopherol, ${\gamma}$-tocopherol, retinol의 수준을 파악하고 혈중 지질상태 및 신체계측치와의 상관성을 평가해보고자 하였으며 조사 대상자는 40대 이후 건강한 성인 373명 (남자 231명, 여자 142명)이었다. 우리나라 건강한 중년기 성인의 혈청 중에 존재하는 주요 carotenoids는 ${\beta}$-cryptoxanthin, ${\beta}$-carotene, lutein이었고 lycopene, ${\alpha}$-carotene은 더 낮은 농도로 존재하였다. 성별에 따른 비교에서는 ${\alpha}$-carotene, ${\beta}$-carotene, ${\beta}$-cryptoxanthin, lycopene 등의 carotenoids 물질들의 농도는 여자가 남자에 비해 유의하게 높았고, retinol은 남자가 여자에 비해 유의하게 높았으며 lutein과 tocopherol은 성별에 따른 유의차를 보이지 않았다. 혈중 항산화 물질의 농도는 연령이 높아짐에 따라 증가하는 경향을 보였으며 retinol과 ${\alpha}$-tocopherol 영양상태는 남자가 여자에 비해 우수하였다. 혈청 항산화 물질들의 농도와 혈청 및 소변 중의 지질과산화물 농도 사이에는 뚜렷한 상관성을 발견할 수가 없었다. 혈청 carotenoids들은 상호간에 또 ${\alpha}$-tocopherol 사이에 유의적인 양의 상관관계를 보였으며, 반면 lutein을 제외하고는 retinol과는 음의 상관성을 나타내었다. 혈 중 ${\alpha}$-tocopherol과 retinol 사이에는 유의적인 양의 상관성을 보였다. 혈 중 지질과의 상관성 분석에서 측정된 모든 항산화 물질들은 총콜레스테롤과 양의 상관관계를 나타내었다. 반면 중성지질은 carotenoids 물질과는 음의 상관성을 보였고 tocopherol, retinol과는 양의 상관성을 보였다. 혈청 항산화 물질들의 농도와 신체계측치 사이에는 성별에 관계없이 전반적으로 혈청 carotenoids류는 신체계측치들 및 혈압과 음의 상관성을 보였으며, tocopherol들과 retinol 수준은 양의 상관성을 보였다. 이 중 특히 유의적인 상관성을 보인 것은 남성에서 ${\beta}$-carotene과 lutein의 혈압과의 음의 상관성, 여성에서의 ${\alpha}$-carotene, ${\beta}$-carotene, ${\beta}$-cryptoxanthin과 체지방 관련 지표들 (BMI, WHR, 체지방율)과의 음의 관련성이었다. 본 연구 결과 중년 성인의 혈중 항산화 물질들의 농도는 종류에 따라 성별, 연령별로 유의적인 차이를 나타내었으며, 혈중 지질 수준 및 신체 계측치와도 유의적인 관련성을 가지는 것으로 나타났다. 따라서 이러한 상관성의 원인과 의미에 대해서는 향 후 식생활 및 생활습관 등과 관련된 연구를 통해 밝혀져야 할 것이다.

Amino Acid Alterations in the $\beta$- Tubulin of Metarhizium anisopliae That Confer Benomyl Resistance

  • Kim Soon Kee;Shim Hee Jin;Roh Jong Yul;Li Ming Shun;Choi Jae Young;Jin Byung Rae;Boo Kyung Saeng;Je Yeon Ho
    • International Journal of Industrial Entomology and Biomaterials
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    • 제11권1호
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    • pp.37-42
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    • 2005
  • We cloned the $\beta$-tubulin genes from the wild type strain and two benomyl-resistant mutants of Metahizium anisopliae and determined their nucleotide sequences. A $\beta$-tubulin encoding 448-residue protein from wild type M. anisopliae shows strong homology to other $\beta$-tubulins. The coding region is interrupted by four introns. Comparisons of intron position between the M. anisopliae gene and other fungal $\beta$-tubulin genes show considerable positional conservation. The mutations responsible for benomyl resistance were determined in two spontaneous mutants, 8-18 and 8­19. One mutant 8-18 substituted glutamate for aspar­agine at position 33 and lysine for glutamine at position 134. The other mutant 8-19 showed alterations at three positions of $\beta$-tubulin arginine for tryptophan at position 21, lysine for asparagine at position 33, and phenylalanine for leucine at position 240. These data suggest that regions of $\beta$-tubulin containing amino acids 21, 33,134, and 240 interact to form the binding site of benomyl.