• The Plant Pathology Journal
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• 제38권4호
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• pp.366-371
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• 2022

The white soybean cyst nematode Heterodera sojae, isolated from the roots of soybean in Korea, is widespread in most provinces of the country and has the potential to be as harmful to soybean as H. glycines. Determining the virulence phenotypes of H. sojae is essential to devising management strategies that use resistant cultivars. Consequently, virulence phenotypes of 15 H. sojae populations from Korea were determined on seven soybean lines and one susceptible check variety. Two different HS types were found to be present in Korea; the more common HS type 2.5.7, comprising 73.3% of the H. sojae populations and the less common HS type 0, constituting only 26.7% of the tested populations. Considering the high frequency of H. sojae adaptation to soybean indicator lines, the PI 88788 group may not be a possible source of resistance while PI 548402, PI 90763, PI 437654, and PI 89772 can be used as resistance sources for soybean breeding programs aimed at developing H. sojae-resistant soybean cultivars in Korea.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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• pp.186-186
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• 1994

Many agonists have been known to activate the hydrolysis of membrane phospholipids through the bindings with corresponding receptors on the various cells. Diacylglycerol and inositol 1,4,5-trisphosphate(IP3) generated by the action of phosphoinositide-specific phospholipase C (PI-PLC) are well known second messengers for the activation of protein kinase C and the mobilization of Ca2+ in many cells. Three types of PI-PLC isozyme (${\alpha}$,${\gamma}$, and $\delta$) and several subtrpes for each type have been identified from mammalian sources by purification of enzymes and cloning of their cDNAs. Each type PI-PLC isozyme is coupled to different receptors and mediators, for example, ${\beta}$-types are coupled to the seven-transmembrane-receptors via Gq family of G-proteins and ${\beta}$-types directly to the receptor tyrosine kinases. Specific modulators for the signaling pathway through each type of PI-PLC should be very useful as potential potential candidates for lend substances in developing novel drugs. To establish the sensitive and convenient screening systems for searching modulators on PI-PLC mediated signaling, two kinds of approaches have been tried. (1) Establishment of in vitro assay condition for each type of PI-PLC isozyme: Overexpression by using vaccinia virus and purification of each isozyme was carried out for the preparation of large amounts of enaymes. Optimum and sensitive assay condition for the measurements of PI-ELC activities were established. (2) Development of the cell lines in which each type of PI-PLC is permanently overexpressed: A fibroblast cell line (3T3${\gamma}$1-7) in which PI-PLC-${\gamma}$1 was overexpressed by using pZip-neo expression vector was developed and used for the measurement of PDGF-induced IP3 formation. The responses for IP3 formed in 3T3${\gamma}$1-7 cells by the treatment of PDGF is 8 times more sensitive than those in control cells. 3T3${\gamma}$l-7 cell is useful for the screening of the inhibitors on the PDGF-induced cellular responses from large number of samples in a small volume(50 ${\mu}$l) and short time(5-15 min). Using these systems, we screened hundreds of herb-extracts for the inhibition of PDGF-induced IP3 formation and selected several extracts that showed the inhibition as the candidates for isolation and characterization of active substances. The determination of the acting point of selected extracts or fractions in the PDGF signaling pathway has been analyzing.

• 제어로봇시스템학회논문지
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• 제5권6호
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• pp.744-752
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• 1999

In this paper, we studied the response characteristics of $\alpha$, $\beta$ separated type, combined type, PI typed, and feedforward type in 2DOF-PID controller through the simulation and the experiments designed with the multivariable flow control system. The parameters $\alpha$ and $\beta$ give an affect to characteristics of controller in separated type but $\gamma$ does not give an affect to the characteristics of 2-DOF PID. The more $\beta$ increases, the more overshoot decreases and especially, in case of PI type represent clearly. The $\alpha$, $\beta$ separated type has a very small overshoot and its magnitudes in 2-DOF PID onctroller increases in order of $\alpha$, $\beta$ combined type, PI type, feedforward type, conventional type. The response characteristics of simulation are similar to that of experiments but the experimental characteristics in the multivariable flow control system has the delayed response. The time delay of response in experiments depends on 2-DOF parameter $\alpha$, $\beta$, $\gamma$ and the overshoot increase as the $\alpha$, $\beta$, $\gamma$ increase. So, we can have a satisfactory response by tuning D gain.

• 조명전기설비학회논문지
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• 제15권3호
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• pp.57-66
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• 2001

본 논문에서는 전력계통의 안정도를 향상시키기 위하여 동기 발전기와 정지형 무효전력 보상기예 대한 퍼지-PI 제어기를 설계하기 위한 제어 기법을 설명하였다. 정지형 무효전력 보상기는 고정된 용량의 커패시터와 싸이리스터 제어에 의하여 용량이 가변되는 인덕터가 병렬로 연결된 구조를 가지고 있으며, 시스템 전압을 제어할 뿐만 아니라 동기 발전기의 제동을 개선하기 위해 설계되었다. 본 논문에서 제안한 SVC 계통의 퍼지-PI 제어기의 파라미터는 퍼지 추론 기법에 의해 자동 동조되어진다. 퍼지 추론 기법은 일반적인 기법과는 달리 인간의 경험과 전문가의 지식을 제어 규칙으로 제어 동작을 결정하였다. 그리하여 인간의 추론 과정과 매우 유사한 MMGM을 이용하여 PI 이득의 퍼지 추론 기법을 SVC 계통에 적용하여 설명하였다. 제안된 방법의 강인성을 입증하기 위해 중부하시, 정상부하시 및 경부하시에 초기 전력을 변동시킨 경우에 대하여 시스템의 회전자각, 각속도 편차 특성 및 단자전압의 동특성을 고찰하여 기존의 전력시스템안정화장치보다 응답특성이 우수함을 보였다.

• Journal of the Korean Statistical Society
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• 제24권2호
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• pp.313-335
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• 1995

Suppose that we have $k(k \geq 2)$ populations (or systems), say $\pi_1, \cdots, \pi_k$, to be tested. Under the type-II censored testing without replacement we consider the problem of estimating the unknown parameters of interests and the reliability for a given time t for each population. Also we compare the perfomances of the proposed Bayes estimators with another estiamtors under the Jeffrey-type noninformative prior distribution.

• 전기학회논문지
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• 제60권10호
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• pp.1978-1983
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• 2011

BLDC motor is used in a wide variety of industrial and servo applications. Its features and advantages mainly consist in high value of torque/inertia ratio, high efficiency with speed range and high dynamic performance. This paper deals with the speed control of a trapezoidal type brushless DC motor using Fuzzy PI controller. The conventional PI controller has been widely used in industrial applications. If we select a optimal PI control gain, the PI controller shows very good control performance. But it is very difficult to find the optimal PI control gain. Fuzzy control does not need any model of plant and is basically adaptive and gives robust performance for plant parameter variation. Therefore the combinations of conventional PI controller and fuzzy controller seem to be very effective. This paper deals with PI controller with 4-rule based fuzzy controller. The proposed fuzzy PI controller increases the control performance of the conventional PI controller. Simulation and experimental results show that fuzzy PI controller has a good robustness regarding the improper tuned PI controller.

• 생명과학회지
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• 제32권2호
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• pp.86-93
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• 2022

Lupeol은 pentacyclic triterpene의 일종으로 다양한 질병에 약리 효과가 있는 것으로 보고되어 있으나, lupeol이 포도당 흡수에 미치는 영향은 아직 보고된 바 없다. 본 연구에서 3T3-L1 지방세포에서 포도당 흡수에 대한 lupeol의 효과를 조사하였다. 그 결과, Lupeol은 3T3-L1 지방세포에서 GLUT4를 원형질막으로 이동시켜 포도당 흡수를 촉진하였으며, 이는 PI3K/AKT 및 AMPK 경로의 활성화와 관련되어 있었다. PI3K/AKT 경로에서 lupeol은 PI3K를 활성화시키는 insulin receptor substrate 1의 인산화와 AKT의 인산화를 촉진하지만 비정형 단백질 키나아제 C isoforms ζ 및 λ의 인산화는 촉진하지 않았다. 반면, lupeol은 5 'AMP-activated protein kinase의 인산화를 촉진하였고, Lupeol의 의한 AMPK의 활성화는 원형질막-GLUT4의 발현과 세포내 포도당 흡수를 증가시키는 것으로 확인되었다. 3T3-L1 지방세포에서 lupeol에 의한 포도당 흡수 효과는 PI3K 억제제인 wortmannin 및 AMPK 억제제인 Compound C에 의해 억제됨을 통해 확인하였다. 본 연구 결과는 lupeol이 3T3-L1 지방세포에서 PI3K/AKT 및 AMPK 경로를 통해 원형질막 GLUT4의 발현을 자극함으로써 인슐린 감수성을 증가시켜 포도당 흡수를 촉진할 수 있음을 제시하고 있다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2000년도 하계학술대회 논문집 B
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• pp.1162-1164
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• 2000

Stratum Axial Type BLDC Motor has remarkable efficiency owing to outstanding characteristics of speed and torque as well as its small size. In this paper 2-Degree of Freedom PI (TDOF PI) control method is presented in order to improve the efficiency of Stratum Axial Type BLDC Motor and the simulation proves that the separate control for speed characteristic from answering characteristic of load torque particularly allows the construction of superior control system to PI control system. These results are significant in that the improved Stratum Axial Type BLDC Motor enables the production of much smaller, lighter, and noiseless electric home appliances such as air-conditioner and refrigerator.

• Journal of Advanced Marine Engineering and Technology
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• 제32권1호
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• pp.147-152
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• 2008

This paper has been fabricated the two different type of variable attenuators using a characteristics of a 3 dB directional coupler and pin diodes. One was not analyzed using the conventional even-odd modes but used simple two-port techniques. The resulting scattering parameters described operation characteristics for the general case where the terminating impedances are equal and unequal. After analyzing resistor role of the ${\pi}$ type fixed attenuator. this paper used a pin diode instead of a resistor. The variable attenuators were fabricated using pin diodes for current-controlled attenuation on the coupled ports of a 3 dB branch-line coupler and ${\pi}$ type fixed attenuator. The realized variable attenuators have more than 33 dB attenuation ranges at 2.1 GHz. and the input and output reflection coefficients are less than -13 dB. These results could be applied to mobile communication systems. It can be varied gain of the power amplifier according to change a outdoor environmental temperature and improved linearity.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2003년도 제5회 학술대회 논문집 일렉트렛트 및 응용기술연구회
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• pp.53-56
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• 2003

Blending effects for generating a pretilt angle in nematic liquid crystal (NLC) with negative dielectric anisotropy on the blended polyimide (PI) of homeotropic and homogeneous alignment surface were studied. Also, we investigated the EO performances for the advanced VA-$\pi$ cell using this homeotropic blended PI surface. A many decrease of tilt angle on the polymer surface to blend homeotropic PI and homogeneous PI with side chain type was measured, and the tilt angle decreased as blended ratio and rubbing strength increase. The blended effects for generating a pretilt angle were clearly observed, and the many decrease of tilt angle can be achieved by using the blended PI surface. The electro-optical (EO) characteristics using the advanced VA-$\pi$ cell using the homeotropic blended PI surface than that of conventional VA cell can be improved. We suggest that the developed advanced VA-$\pi$ cell on a homeotropic blended PI surface is a promising technique for the achievement of a fast response time, and a high contrast ratio.