• 제목/요약/키워드: "The Hours"

검색결과 19,675건 처리시간 0.043초

5-Fluorouracil이 생쥐의 간에 미치는 세포독성에 대한 Squalene의 영향 (The Effect of Squalene on the Cellular Toxicity of 5-Fluorouracil to the Mouse Liver)

  • 김정상;김재성;박정석;최완수;최영복;김종세
    • Applied Microscopy
    • /
    • 제27권2호
    • /
    • pp.165-175
    • /
    • 1997
  • This paper aims to prove the effects of Squalene (SQ) on the cellular toxicity of 5-FU to the mouse which pretreated with SQ and then treated with 5-FU. The results of the group A (treated with only 5-FU) are as follows. The nucleus was destroyed at 24 hours and 48 hours group, however, somewhat repaired at 72 hours group. The dilated inner cavity and the irregular lamellae of the rough surfaced endoplasmic reticulum (RER) were observed continually until 72 hours group. The inner cavity of the smooth surfaced endoplasmic reticulum (SER) were dilated in all groups. However, the destroyed and the normal membrane were observed simultaneously at 72 hours group. The inner membrane of the mitochondria were almost repaired at 96 hours group. The results of the group B (treated with 5-FU and squalene) are as follows. The nucleus was a little influenced by the toxicity of 5-FU at 24 hours and 48 hours, RER were observed to keep the typical lamella structure of cisternae from 24 to 72 hours group, but inner cavity kept on dilating. In SER, inner cavity were also observed to flatten from 24 to 72 hours group. Mitochnodria were always shown normal. All cell organelles were simillar to those of normal groups at 96 hours. Accordingly, it can be said that the treatment of 50 prevents the cytotoxicity of 5-FU on cell organelles of liver cell and that is concerned with the formation of membrane system of cell organelles.

  • PDF

VDT 작업시간의 관련성 분석 (The relationship analysis in VDT of work hours)

  • 강점덕
    • 대한정형도수물리치료학회지
    • /
    • 제9권1호
    • /
    • pp.19-28
    • /
    • 2003
  • Objectives : This study was to investigate the relationship analysis in VDT(visual display terminal) of work hours. Methods : Questionnaires were completed by 41 women in VDT operations. The information was used to estimate multiple regression for the VDT of work hours related factors association. Results : The prevalence of the VDT of work hours was significantly higher in the shoulder which followed by the neck, the hand and fingers, the arms, the lowback, the back. The VDT of work hours decreased with aging. The VDT of work hours increased with work duration, single, lower among habitual exercise. The desk height, the seat pan height, the posture on the sitting, the elbow angle all did not meet the recommended criteria. Conclusions : Data from this study support a statistically significant association with satisfaction for occupation.

  • PDF

축소모형 실험을 통한 일조창과 태양의 기하학적 위치관계에 따른 실내조도분포 특성 (The Effect of Geometric Relation between the Window and the Sun on the Interior Illuminance Distributions using a Physical Scale Model)

  • 김민성;송규동
    • KIEAE Journal
    • /
    • 제5권3호
    • /
    • pp.33-40
    • /
    • 2005
  • The existing building code regulates the minimum distance between buildings and the minimum required sunshine hours for winter solstice to ensure the right to light. Especially, the minimum sunshine hours have been guaranteed by the constitution after the right for the people to live in a healthy and comfortable environment was established. However, the existing regulation on the sunshine hours only considers the duration of sunshine hours, but ignores the minimum amount of sunlight. Therefore, the calculated sunshine hours are not coincident with the hours occupants actually feel. Therefore, the purpose of this study is to investigate the effect of solar incident angle on interior illuminance distribution, which will be used to propose a new code on the minimum sunshine hours and levels.

강정과 산자류 제조에 관한 실험조리적 연구 (I) -침수시간에 따른 강정과 산자의 질감에 관한 연구- (Experimental Study of Gangjung and Sanja(I) -The Study of Texture of Gangjung and Sanja Prepaed with Soaking Time-)

  • 김태홍
    • 대한가정학회지
    • /
    • 제19권3호
    • /
    • pp.63-68
    • /
    • 1981
  • This study was to determine optimal conditions for preparing Gangjung and Sanja. Texturometer and panel test were employed to evaluated products which were prepared under varying soaking time of glutinous rice. The results are found as follows; Examination of acceptibilities of products by the panel test showed that 48 hours of soaking was the most optimal. In acceptability ratings. the second went to 2 hours, the third 24 hours, the forth 120 hours, the fifth, 72 hours, and the sixth, 96 hours. However, there was no significant difference in acceptability among various products(P>0.05). The cohesiveness and the brittleness of the highest-grade products soaking in 48 hours showed 0.09$cm^{2}$, 1.25cm, respectively by texturometer. In therms of acceptability, the cohesiveness of high-grade products read between 0.06~0.7$cm^{2}$. The brittleness of products examined was in the range of between 0.36 and 1.41cm. No significant difference was found among products prepared under varying soaking time n cohesiveness and brittleness.

  • PDF

근로시간에 따른 근로자들의 직무스트레스 (The Relationship between working Time and Job Stress)

  • 이윤경;정혜선;장원기
    • 한국직업건강간호학회지
    • /
    • 제15권2호
    • /
    • pp.115-125
    • /
    • 2006
  • Purpose: This study analyzed the amount of stress and the different effects according to the working times(hours) of a week in two groups: more than 40 hours a week and less than 40 hours a week. Method: The study was conducted from November 1st 2005 to December 15th 2005. The purpose of the study has already been explained in the experiment objectives. 20 copies of evaluation forms were sent by mail to 50 different health sections of participating work sites. A total of 1,000 copies were sent out and 870 were sent back. Within the forms, sent back 120 copies had insufficient data, so 750 copies of evaluation forms were analyzed. Result: Working stress for under 40 hours of working time showed a total of 46.10 points and 47.18 for over 40 hours of working time. For over 40 hours, job demand and occupational climate was high and under 40 hours showed a high rate of job control. For under 40 hours of working time, the factors that caused stress were female, irregular diet habit, age of 30's, nonmanufacturing, and single. For over 40 hours of working time, the factors that causes stress were age of over 40, when the number of employees is 500~999, high rate of fatigue, when the position of the employee is higher then section chief, and when the work amount is high. Conclusion: The stress rate showed significantly higher in over 40 hours of working time. Therefore, adequate working hour distribution and health promotion programs are needed. The factors that cause stress in both under and over 40 hours of working time differed. Therefore, a distinguished program to control work stress for additional working time is needed.

  • PDF

UVB 조사로 인한 마우스 피부조직의 산화적 손상 (A Study on the Oxidative Damage Induced by UVB Irradiation to Mouse Skin)

  • 이승자;김영철
    • Environmental Analysis Health and Toxicology
    • /
    • 제21권2호
    • /
    • pp.165-172
    • /
    • 2006
  • The backs with a hair cut of 6-week-old healthy ICR male mice were once exposed to a dose of $400mJ/cm^2$ UVB. An acute dermal inflammation was observed, and the inflamed skins were almost completely cured after 6 days of the exposure. At 24 hours after exposure, the epidermal keratinocytes showed a cell-membrane damage with the destruction of intercellular junctions, agglutination of tonofilaments within the cytoplasm and nucleus damage. The activity of XO showed a significant increase (p<0.05) in up to 144 hours. The activities of CAT and SOD showed a significant decrease (p<0.05) in up to 96 hours, but they were not significantly different from the normal value at 144 hours. The GST activity was significantly decreased (p<0.01) in up to 96 hours, not so at 24 hours. However, that was not significantly different from the normal value at 144 hours. There was a significant decrease (p<0.01) in the contents of TBARS at 48 and 96 hours, without any significant difference at 144 hours. While the content of GSH was significantly lower (p<0.05) at 24 hours, that was not significantly different thereafter up to 144 hours from the normal value. Therefore, it is assumed that skin damage with a dose of $400mJ/cm^2$ UVB irradiation might be caused by the oxidative stress which was resulted from the unbalance of oxygen fret radical generating and scavenging enzymes.

보리 유식물 분리엽록체의 광합성 전자전달활성에 미치는 Dimethipin의 영향 (Effects of Dimethipin on the Photosynthetic Electron Transport Activity of Isolated Barley Chloroplasts)

  • 이준상
    • 환경생물
    • /
    • 제23권1호
    • /
    • pp.52-56
    • /
    • 2005
  • 8일간 생장한 보리 유식물에 72시간 동안 dimethipin을 처리하면서 엽록소 함량의 변화와 광합성적 전자전달 활성을 측정하였다. 10/sup -3/M dimethipin을 72시간 처리한 경우 엽록소 함량이 33% 감소하였다. 이에 비해 7일간 암소에서 생장시킨 후 dimethipin을 처리한 보리 유식물은 녹화 48시간에 10/sup -4/M에서 대조구에 비해 43% 엽록소 함량이 감소하였으며, 엽록소 a/b 비율이 증가하였다. 24시간의 dimethipin처리는 PSⅡ+PSⅠ활성에 거의 영향을 미치지 않았다. 10/sup -4/M dimethipin처리는 48시간 배양시 10% 그리고 72시간에는 25%의 PSⅡ+PSⅠ 활성을 억제하였다. Water splitting system을 제외한 PSⅡ+PSⅠ 활성은 10/sup -4/M dimethipin을 48시간 처리할 경우 16% 그리고 72시간에는 27% 억제되었다. 10/sup -4/M dimethipin을 24시간 처리할 경우 PSⅡ활성은 8%, 48시간에서는 13% 그리고 72시간에서는 18% 억제되었다. 10/sup -4/M dimethipin을 24시간 처리할 경우 PSⅠ활성은 4%, 48시간에서는 8% 그리고 72시간에서는 10% 억제되었다. 7일간 암소에서 자란 황백화된 보리 유식물을 녹화시간 6, 12, 24와 48시간에 dimethipin을 처리할 경우 PSⅡ+PSⅠ 활성은 5, 10, 10 그리고 11% 억제되었다. 반면에 water splitting system을 제외한 PSⅡ+PSⅠ 활성은 모든 처리시간에서 그 효과가 없었다. 또한 PSⅡ와 PSⅠ의 활성도 대조구와 큰 차이가 없었다. 이와 같이 dimethipin에 의해 야기된 광합성적 전자전달활성의 억제는 엽록체 합성과정에서의 영향보다는 엽록체의 기능에 영향을 주는 것으로 사료되며, 이러한 엽록체 기능의 감소는 dimethipin에 의해 야기되는 30∼40%의 엽록소 함량감소에 의한 것으로 사료된다.

제 6기 국민건강영양조사 자료(2015)를 활용한 대사증후군 유병과 근로시간에 관한 연구 (A Study on the Relationship Between Metabolic Syndrome and the Number of Work Hours Based on Data from the 6th Korea National Health and Nutrition Examination Survey (2015))

  • 김경윤;신현지;윤정미
    • 한국식생활문화학회지
    • /
    • 제34권4호
    • /
    • pp.486-494
    • /
    • 2019
  • There are an increasing number of reports that job related factors are associated with hypertension, sleep deprivation, obesity and diabetes. This study analyzed the relationship of working type, working hours and the prevalence of metabolic syndrome. The study's subjects were 2,777 employees (1,446 males and 1,331 females) over 19 years old and their data was from the Korea National Health and Nutrition Survey (2015). The type of work was divided into day work and shift work. The working hours were divided into less than 40 hours, 40 to 49 hours, 50 to 59 hours and 60 hours or more per week. As a result of this study, the prevalence of metabolic syndrome was 26.4% of the males and 19.1% of the females. Generally there was no relationship between metabolic syndrome and type of work (day work and shift work). As a result of analysis of working hours and metabolic syndrome, the workers who worked 40-49 hr were associated with a decreased prevalence of metabolic syndrome as compared to that of workers who worked less than 40 hr (odds ratio: 0.47, 95% confidence interval: 0.24-0.95, p<0.05). Further, positive relationships were found between the number of work hours and the prevalence metabolic syndrome for specific females who worked over 40 hr/wk. It can be concluded from the results that it is important to help workers avoid metabolic syndrome through setting appropriate work hours.

연장근로에 따른 아동돌봄 형태와 일 가족 갈등: 초등학생 이하 자녀를 둔 취업모를 중심으로 (Variations in Childcare Style and Work-Family Conflict Related to Extended Working Hours: Focusing on Employed Mothers of Preschoolers or Elementary-School Children)

  • 성혜영
    • 대한가정학회지
    • /
    • 제48권9호
    • /
    • pp.79-87
    • /
    • 2010
  • The purpose of this study was to investigate whether employed mothers' extended working hours have effects on childcare style and work-family conflicts. The data came from the 2007 Korean Longitudinal Survey of Women and Family(KLoWF) of the Korean Women's Development Institute. 475 females with preschoolers or elementary-school children were used in this study. The major findings can be summarized as follows: (1) Weekly average working hours varied by education, salary, and the presence of preschoolers. (2) The time of childcare was significantly shorter in mothers who work more than 50 hours/week (3) Mothers who worked more than 50 hours/week felt significantly high work-family conflict. These analyses pointed to the importance of obeying the law related to working hours as the most important thing to sustain work-family balance. Institutional foundations should be enabled to keep legal working hours.

군용시설물(軍用施設物) 폐수처리(廢水處理)를 위한 고정생물막공법(固定生物膜工法)의 연구(硏究) (A Study on the Aerated Submerged Fixed-Film Bioreactor for Military Installation Wastewater Treatment)

  • 서형석;유성호
    • 상하수도학회지
    • /
    • 제7권1호
    • /
    • pp.37-45
    • /
    • 1993
  • This research was performed to examined the applicability of a fixed-biofilm process for the wastewater treatment of military installations. Utilizing plastic net media, synthetic wastewater-average $BOD_5$ cocentration was $192mg/l$ treated in the three sets of reactors that have 8 hours, 6 hours, and 4 hours of hydraulic retention time. The results of this experiment showed that the biofilm was not detached easily, and the reactor was not closed by excess biomass. The average soluble $BOD_5$ concentrations of effluent were $6.0mg/l$ with 8 hours of retention time, $11.3mg/l$ with 6 hours of retention time, and $19.4mg/l$ with 4 hours of retention time. Especially it was reduced to $5.7mg/l$ in the second stage reactor with 4 hours of retention time. These resulted that the fixed-biofilm process could be adapted for the treatment of military installation wastewater.

  • PDF