Compared to metal-to-metal tribology, polymer tribology presents further complexity as it is more prone to be influenced by operating conditions. Over the past two decades, progress in the field of wear of polymers has led to the establishment of more refined wear mechanisms. The current paper establishes the link between different load parameters and the wear rate of polymers, based on experimental investigations. A pin-on-plate reciprocating tribometer was used to examine the wear behaviour of polyamide sliding against a steel counterface, under constant and fluctuating loads, in dry conditions. In addition, the influence of controlled imperfections in the polymer surface upon its wear rate were examined, under cyclic and steady loading, in order to better understand surface fatigue wear of polymers. The imposed imperfections consisted of vertical artificial deep crack (slit) perpendicular or parallel to the direction of sliding. The study concludes with the followings findings; in general, wear of polymers shows a significant tendency to the type of applied load. Under cyclic loads, polymers show an increase in wear rate compared to those tested under static loads. Such increase was found to increase with the increase in cyclic load frequency. It is also demonstrated that surface cracks results in higher wear rates, particularly under cyclic loads.