For the measurement of biophysical properties related with cardiovascular diseases (CVD), various microfluidic devices were proposed. However, many devices were monitored by optical equipment. Ultrasound measurement to quantify the biophysical properties can provide new insights to understand the cardiovascular diseases. This study aims to check feasibility of microfluidic device for ultrasound image analysis based on 3D printer. To facilitate acoustic transmission, agarose solution is poured around 3D mold connected with holes of the acrylic box. By applying speckle image velocimetry(SIV) technique, flow information in the bifurcated channel was estimated. Considering that ultrasound signal amplitude is determined by red blood cell (RBC) aggregation, RBC aggregation in the bifurcated channel can be estimated through the analysis of ultrasound signal. As examples of microfluidic device which mimic the CVD model, velocity fields in microfluidic devices with stenosis and aneurysm were introduced.

Homogeneous and isotropic turbulence (HIT) with no mean flow is a very useful type of flow for basic turbulence research. However, it is difficult to generate HIT in the lab. In this study, we implemented HIT in a confined box through synthetic jet actuators using sub-woofer speakers. Characteristics of HIT are varied depending on the strength of the jets. We used 2D PIV to measure the velocity field. Turbulence statistics such as homogeneity, isotropy ratio, turbulence kinetic energy, dissipation rate, Taylor microscale, Kolmogorov scale, and velocity correlation coefficient were calculated. Most of the turbulence statistics increased exponentially according to the strength of the jets, and the Taylor Reynolds number reached up to 185.

In the present study, we investigate the flow characteristics of a quadrotor UAV in a hovering mode by measuring multiple two-dimensional velocity fields in the wake. The experiment is conducted at Re = 24,000 in a chamber large enough to neglect the ground effect, where Re is the Reynolds number based on the rotor chord length and the rotor tip speed. The rotational speed of the rotor is determined by an optical tachometer so that the lift force can be balanced with the weight of the UAV. The velocity field measured on the center plane of the rotor shows that the vortices are shedding from the tip of the rotor, inducing large fluctuations in the streamwise velocity along the wake shear layer. The strength of the rotor-tip vortex shedding is asymmetric with respect to the rotor axis due to the interaction between the rotor and the wake centerline of each rotor is inclined to the center of the UAV due to the pressure difference caused by the induced velocity. The wake from each rotor moves closer to each other while traveling in the streamwise direction, and then is merged together inducing large fluctuations in the transverse velocity. Due to the wake merging, on the center plane of the UAV, the velocity increases in the streamwise direction showing two-peak structure in the streamwise velocity contours.

The two-fluid model is widely used for practical applications involving multi-phase flows in chemical reactor, nuclear reactor, desalination systems, boilers, and internal combustion engine. There are several modeling terms in the two-fluid model, which must be determined properly. This study suggests the best models for turbulent vertical bubbly flow.

A needle-free injector is one of the new non-invasive players in impregnating the biological barriers. It is considered as the next phase in drug delivery and therapeutic applications. One of the major fields of application is in skin remodeling procedures. Although many studies were carried out in understanding the principle in the needle-free injection procedure, fewer studies were done with the aim of therapeutic applications. In the present study, we tried to identify key parameters that affect the jet divergence and peak stagnation pressure on the skin surface in a conventional needle-free injector for skin treatment. A summary of the working principle and effect of the key parameters are presented.

In this study, the effect of injection pressure on the column diameter and droplet velocity of liquid jet with the weakly turbulent Rayleigh-like breakup mode is experimentally studied using digital microscopic holography (DMH). The injection nozzle has the diameter of $50{\mu}m$ and injection pressure is varied from 0.1 to 0.4 MPa. When the micro liquid jet is injected into still air, the double-pulsed holograms was recorded on a CCD sensor and numerically reconstructed in order to obtain well focused images. In this study, the liquid column diameter from $50{\mu}m$ orifice nozzle is shown to be changed slightly but the droplet velocity is increased proportionally as the injection pressure is increased.

It is important to develop more efficient and productive casting processes for an automated high precision molten-metal casting system. Detailed analysis of molten-metal flow in the casting process by the numerical approach will help to optimize the control of a ladle. In this study, the smoothed particle hydrodynamics method was applied to analyze casting flow characteristics with different tilting angular speed and initial molten-metal level. The smoothed particle hydrodynamics technique has advantages to easily handle non-linear free surface behavior with the absence of a computational mesh. We found that tilting angular speed has relatively greater effect on the casting flowrate and that the effect of the initial molten-metal level is only minor. Further extensive study will be necessary to find an optimal condition for high efficient casting system.

Ion exchange membrane can transfer only cation or anion in electrically conductive fluids. Recent studies have revealed that such selective ion transport can initiate electroconvective instability, resulting vortical fluid motions on the membrane. This so-called electroconvective vortex (a.k.a. electroconvection (EC)) has been in the spotlight for enhancing an ion flux in electrochemical systems. However, EC under shear flow has not been investigated yet, although most related systems operate under pressure-driven flows. In this study, we present the direct visualization platform of EC under shear flow. On the transparent silicone rubber, microscale channels were fabricated between ion exchange membranes, while allowing microscopic visualization of fluid flow and ion concentration changes on the membranes. By using this platform, not only we visualize the existence of EC under shear flow, its unique characteristics are also identified: i) unidirectional vortex pattern, ii) its advection along the shear flow, and iii) shear-sheltering of EC vortices.