DOI QR코드

DOI QR Code

한국 청소년의 현증 알레르기질환과 정신건강 문제의 연관성: 2022년 한국 청소년건강행태조사 분석

Higher anxiety, stress, and suicidal behaviors in allergic adolescents: A Nationwide Korea Youth Risk Behavior Web-Based Survey 2022

  • 이민정 (서울대학교 의과대학 서울대학교병원 소아청소년과) ;
  • 박지수 (서울대학교 의과대학 서울대학교병원 소아청소년과) ;
  • 서동인 (서울대학교 의과대학 서울대학교병원 소아청소년과)
  • Min Jeong Lee (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Ji Soo Park (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Dong In Suh (Department of Pediatrics, Seoul National University College of Medicine)
  • 투고 : 2024.03.12
  • 심사 : 2024.04.16
  • 발행 : 2024.10.30

초록

Purpose: Allergic diseases are prevalent among adolescents, while mental health issues significantly contribute to their disease burden. This study investigated the relationship between the onset time points of specific allergic diseases and the prevalence of perceived mental health problems in adolescents. Methods: We used data from the 2022 Korea Youth Risk Behavior Web-based Survey (KYRBS) to examine the prevalence of allergic diseases and psychological issues such as stress, anxiety, depression, and suicidal behaviors. Participants were classified into three groups: current (diagnosis within the past year), remote (previous but not current diagnosis), and never (no history of such diseases), where the prevalence of psychological issue was assessed and compared. Results: Of the 51,850 respondents, 1.2% had current asthma, 16.7% allergic rhinitis, and 5.9% atopic dermatitis. Conversely, 94.3%, 64.7%, or 77.9% of the patients had never been diagnosed with these conditions, respectively. High stress was reported by 41.3% of the patients, substantial depression by 12.7% of the patients, and moderate-to-severe anxiety by 28.8% of the patients, with 14.2% of the patients contemplating suicide. Most of the allergic conditions and across the 3 onset time points, there were significant differences in the prevalence of mental health issues (namely, high stress, substantial depression, moderate-to-severe anxiety), as well as suicidal behaviors including suicidal ideation, planning, and attempts, with the highest prevalence in the current group and the lowest in the never group. Conclusion: There may be a significant association between allergic diseases and mental health problems in adolescents. The prevalence of mental issues is the highest in those with current allergic diagnosis, suggesting a need for integrated care strategies.

키워드

참고문헌

  1. Calvo M, Fernando G. Allergic diseases, from the infant to the adolescent. In: Pablo B, Ignacio S, editors. Pediatric Respiratory Diseases. Cham (Switzerland): Springer, 2020:383-92.
  2. Pawankar R. Allergic diseases and asthma: a global public health concern and a call to action. World Allergy Organ J 2014;7:12.
  3. Asher I, Pearce N. Global burden of asthma among children. Int J Tuberc Lung Dis 2014;18:1269-78.
  4. Knibb RC, Alviani C, Garriga Baraut T, Mortz CG, Vazquez-Ortiz M, Angier E, et al. The effectiveness of interventions to improve self-management for adolescents and young adults with allergic conditions: a systematic review. Allergy 2020;75:1881-98.
  5. Sterner T, Uldahl A, Svensson A, Bjork J, Svedman C, Nielsen C, et al. The southern Sweden adolescent allergy-cohort: prevalence of allergic diseases and cross-sectional associations with individual and social factors. J Asthma 2019;56:227-35.
  6. Oh J, An J. Depressive symptoms, emotional aggression, school adjustment, and mobile phone dependency among adolescents with allergic diseases in South Korea. J Pediatr Nurs 2019;47:e24-9.
  7. Korczak DJ, Westwell Roper C, Sassi R. Diagnosis and management of depression in adolescents. CMAJ 2023;195:E739-46.
  8. Ahn DH. Mental disorders in adolescents. J Korean Med Assoc 2009;52:745-57.
  9. Remschmidt H, Belfer M. Mental health care for children and adolescents worldwide: a review. World Psychiatry 2005;4:147-53.
  10. Tzeng NS, Chang HA, Chung CH, Kao YC, Chang CC, Yeh HW, et al. Increased risk of psychiatric disorders in allergic diseases: a nationwide, population-based, cohort study. Front Psychiatry 2018;24:133.
  11. Budu-Aggrey A, Joyce S, Davies NM, Paternoster I, Munafo MR, Brown SJ, et al. Investigating the causal relationship between allergic disease and mental health. Clin Exp Allergy 2021;51:1449-58.
  12. Ferro MA, Van Lieshout RJ, Scott JG, Alati R, Mamun AA, Dingle K. Condition-specific associations of symptoms of depression and anxiety in adolescents and young adults with asthma and food allergy. J Asthma 2016;53:282-8.
  13. Nguyen CM, Koo J, Cordoro KM. Psychodermatologic effects of atopic dermatitis and acne: a review on self-esteem and identity. Pediatr Dermatol 2016;33:129-35.
  14. Dave ND, Xiang L, Rehm KE, Marshall GD Jr. Stress and allergic diseases. Immunol Allergy Clin North Am 2011;31:55-68.
  15. Kim Y, Choi S, Chun C, Park S, Khang YH, Oh K. Data resource profile: the Korea youth risk behavior web-based survey (KYRBS). Int J Epidemiol 2016;45:1076-1076e.
  16. Spitzer RL, Kroenke K, Williams JB, Lowe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 2006;166:1092-7.
  17. Byrd-Bredbenner C, Eck K, Quick V. GAD-7, GAD-2, and GAD-mini: psychometric properties and norms of university students in the United States. Gen Hosp Psychiatry 2021;69:61-6.
  18. Chun YH, Han K, Park YG, Yoon JS, Kim HH, Kim JT, et al. Examining impacts of allergic diseases on psychological problems and tobacco use in Korean adolescents: the 2008-2011 Korean national health and nutrition examination survey. PLoS One 2015;10:e0125172.
  19. Mallol J, Crane J, Von Mutius E, Odhiambo J, Keil U, Stewart A. The international study of asthma and allergies in childhood (ISAAC) phase three: a global synthesis. Allergol Immunopathol (Madr) 2013;41:73-85.
  20. Lee YH, Choi J, Park MR, Kim J, Kim WK, Park YM, et al. Analysis of regional prevalence of allergic diseases in Korean school children. Allergy Asthma Respir Dis 2015;3:62-9.
  21. Statistical reports in cause of death 2022 [Internet]. Daejeon (Korea): Statistics of Korea (KOSTAT); 2022 [cited 2024 Mar 12]. Available from: https://kostat.go.kr/board.es?mid=a10301060200&bid=218&act=view&list_no=427216.
  22. Choi JW, Moon HY, Jeon JA, Park YC. Survey on the mental health of adolescent. Sejong (Korea): National Youth Policy Institute. 2021:10-4.
  23. Park CH. Mental health in adolescents with allergic diseases-using data from the 2020 Korean youth's risk behavior web-based study. J Ind Converg 2022;20:87-96.
  24. Jafferany M. Psychodermatology: a guide to understanding common psychocutaneous disorders. Prim Care Companion J Clin Psychiatry 2007;9:203-13.
  25. Blaiss MS, Hammerby E, Robinson S, Kennedy-Martin T, Buchs S. The burden of allergic rhinitis and allergic rhinoconjunctivitis on adolescents: a literature review. Ann Allergy Asthma Immunol 2018;121:43-52.e3.
  26. Beasley R, Hancox JR. Reducing the burden of asthma: time to set research and clinical priorities. Lancet Respir Med 2020;8:943-4.
  27. Fasseeh AN, Elezbawy B, Korra N, Tannira M, Dalle H, Aderian S, et al. Burden of atopic dermatitis in adults and adolescents: a systematic literature review. Dermatol Ther (Heidelb) 2022;12:2653-68.
  28. Wertz DA, Pollack M, Rodgers K, Bohn RL, Sacco P, Sullivan SD. Impact of asthma control on sleep, attendance at work, normal activities, and disease burden. Ann Allergy Asthma Immunol 2010;105:118-23.
  29. Koinis-Mitchell D, Craig T, Esteban CA, Klein RB. Sleep and allergic disease: a summary of the literature and future directions for research. J Allergy Clin Immunol 2012;130:1275-81.
  30. Voorhees JL, Tarr AJ, Wohleb ES, Godbout JP, Mo X, Sheridan JF, et al. Prolonged restraint stress increases IL-6, reduces IL-10, and causes persistent depressive-like behavior that is reversed by recombinant IL-10. PLoS One 2013;8:e58488.
  31. Trueba AF, Ritz T, Trueba G. The role of the microbiome in the relationship of asthma and affective disorders. Adv Exp Med Biol 2016;874:263-88.
  32. Park JS, Cho YJ, Yun JY, Lee HJ, Yu JH, Yang HJ, et al. Leukotriene receptor antagonists and risk of neuropsychiatric events in children, adolescents and young adults: a self-controlled case series. Eur Respir J 2022;60:2102467.
  33. Yang HJ, Kim YH, Lee B, Kong DY, Kim DK, Kim MA, et al. Unmet primary physicians' needs for allergic rhinitis care in Korea. Allergy Asthma Immunol Res 2017;9:265-71.