Animal Bioscience

  • 제37권6호
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  • Pages.1041-1052
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  • 2024
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  • 2765-0189(pISSN)
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  • 2765-0235(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
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Bacillus subtilis improves antioxidant capacity and optimizes inflammatory state in broilers

  • Yu Zhang (Animal Science and Technology College, Beijing University of Agriculture) ;
  • Junyan Zhou (Animal Science and Technology College, Beijing University of Agriculture) ;
  • Linbao Ji (College of Animal Science and Technology, China Agricultural University) ;
  • Lian Zhang (College of Animal Science and Technology, China Agricultural University) ;
  • Liying Zhao (Animal Science and Technology College, Beijing University of Agriculture) ;
  • Yubing Guo (Animal Science and Technology College, Beijing University of Agriculture) ;
  • Haitao Wei (Animal Science and Technology College, Beijing University of Agriculture) ;
  • Lin Lu (Animal Science and Technology College, Beijing University of Agriculture)
  • 투고 : 2023.08.27
  • 심사 : 2024.01.08
  • 발행 : 2024.06.01
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초록

Objective: Bacillus subtilis, a kind of probiotic with broad-spectrum antibacterial function, was commonly used in livestock and poultry production. Recent research suggested that Bacillus subtilis may have antioxidant properties and improve immune response. This study aimed to verify the probiotic function of Bacillus subtilis in the production of broiler chickens. Methods: A total of 324 (1-day-old) Arbor Acres broilers were selected and randomly divided into three groups: basal diet group (Ctr Group), basal diet + antibiotic growth promoter group (Ctr + AGP) and basal diet + 0.5% Bacillus subtilis preparation group (Ctr + Bac). The experiment lasted for 42 days. Muscle, serum and liver samples were collected at 42 days for determination. Results: The results showed that Bacillus subtilis could decrease malondialdehyde content in the serum and liver (p<0.05) and increase superoxide dismutase 1 mRNA expression (p<0.01) and total superoxide dismutase (p<0.05) in the liver. In addition, compared with AGP supplementation, Bacillus subtilis supplementation increased interleukin-10 (IL-10) and decreased tumor necrosis factor-α and IL-1β level in the serum (p<0.05). At 45 minutes after slaughter Ctr + Bac presented a higher a* value of breast muscle than Ctr Group (p<0.05), while significant change in leg muscle was not identified. Moreover, there was no difference in weight, shear force, cooking loss and drip loss of breast and leg muscle between treatments. Conclusion: Our results demonstrate that Bacillus subtilis in diet can enhance antioxidant capacity and optimize immune response of broilers.

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과제정보

This work was financially supported by the Beijing Innovation Team of the Modern Agricultural Research System BAIC08-2024-SYZ03 and Science and Technology innovation support program of Beijing University of Agriculture (BUA-HHXD2023009).

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