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Design of 3D printed chip for thrombus measurement and feasibility study for smoking effect

혈전 측정용 3D printed chip 설계 및 흡연의 영향 사전 연구

  • Haebeen Kim (School of Mechanical Engineering, PNU) ;
  • Eunseop Yeom (School of Mechanical Engineering, Pusan National University (PNU))
  • Received : 2023.02.24
  • Accepted : 2023.03.18
  • Published : 2023.03.31

Abstract

Thrombogenesis, which is the process of blood clot formation, can be initiated by platelet activation. Excessive formation of blood clot in the bloodstream can lead to thrombosis. Therefore, when dealing with patients with disseminated intravascular coagulation (DIC) or children, it is necessary to use small amounts of blood. Hence, it is important to develop methods for the rapid and accurate measurement of the platelet function using a small amount of blood. In this study, 3D printing technology was utilized to facilitate the production of micro channels. The amount of platelet adhesion in smokers and non-smokers was compared by repeatedly exposing the structure of the channel to adjust the number of blood injections and facilitate thrombosis attachment to simple stenosis structures.

Keywords

Acknowledgement

이 성과는 2018년도 정부(과학기술정보통신부)의 재원으로 한국연구재단의 지원을 받아 수행된 연구임(No. NRF-2018R1A5A2023879).

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