Clinical Nutrition Research

  • 제11권4호
  • /
  • Pages.331-346
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  • 2022
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  • 2287-3732(pISSN)
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  • 2287-3740(eISSN)
한국임상영양학회 (The Korean Society of Clinical Nutrition)
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Obesity, Diabetes Mellitus, and Metabolic Syndrome: Review in the Era of COVID-19

  • Behnaz Abiri (Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences) ;
  • Amirhossein Ramezani Ahmadi (Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences) ;
  • Mahdi Hejazi (Department of Nutrition, School of Public Health, Iran University of Medical Sciences) ;
  • Shirin Amini (Department of Nutrition, Shoushtar Faculty of Medical Sciences)
  • 투고 : 2022.05.19
  • 심사 : 2022.10.16
  • 발행 : 2022.10.31
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초록

Coronavirus disease 2019 (COVID-19), a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now at pandemic levels leading to considerable morbidity and mortality throughout the globe. Patients with obesity, diabetes, and metabolic syndrome (MetS) are mainly susceptible and more probably to get severe side effects when affected by this virus. The pathophysiologic mechanisms for these notions have not been completely known. The pro-inflammatory milieu observed in patients with metabolic disruption could lead to COVID-19-mediated host immune dysregulation, such as immune dysfunction, severe inflammation, microvascular dysfunction, and thrombosis. The present review expresses the current knowledge regarding the influence of obesity, diabetes mellitus, and MetS on COVID-19 infection and severity, and their pathophysiological mechanisms.

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참고문헌

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